Clinical trials: Patients With Prostate Cancer, open to volunteers
Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy
A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery
A single arm prospective pilot trial evaluating the 1-year erectile recovery outcomes and the safety of patients undergoing a somatic to autonomic nerve grafting procedure for restoration of erectile function in patients who have…
- Trial name
- PRP NG PRO M (NCT07188064)
- Testing
- Post radical prostatectomy nerve restoration procedure (PRP-NR)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Prostate Cancer (Adenocarcinoma), Vitamin D on Tumor Response and Inflammatory Markers
Comparative Analysis of Immunological Responses to Vitamin D Replacement Therapy in Black and West African Men Diagnosed With Prostate Cancer: Elucidating Differential Effects on Immune Function Between Patients With Localized Disease and Those With Metastatic Progression
This study is testing whether fixing vitamin D deficiency in Black/West African men with prostate cancer can strengthen their immune system, improve quality of life, and even slow cancer progression compared to those who remain…
- Trial name
- iCCaRE (NCT07598032)
- Testing
- vitamin D 25(OH)D
- Where
- Nigeria
- Volunteers
- 200 people
- Sponsor
- University of Ilorin Teaching Hospital
Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma
Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
This phase I/II trial tests the safety and effectiveness of cell therapy (STEAP1 CART) with enzalutamide in treating patients with prostate cancer that continues to grow despite surgical or medical treatments to block androgen…
- Conditions
- Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8
- Trial name
- NCT06236139
- Testing
- Anti-STEAP1 CAR T-cells, Biopsy Procedure, Biospecimen Collection
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Fred Hutchinson Cancer Center
Prostate Adenocarcinoma, Stage II Prostate Cancer AJCC v8
Hormone Therapy (Apalutamide) and Image-guided Stereotactic Body Radiation Therapy for the Treatment of Patients With Prostate Cancer, HEATWAVE Trial
This phase II trial evaluates apalutamide in combination with image-guided stereotactic body radiation therapy (SBRT) for the treatment of patients with prostate cancer.
- Conditions
- Prostate Adenocarcinoma, Stage II Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8
- Trial name
- HEATWAVE (NCT06067269)
- Testing
- Apalutamide, Biospecimen Collection, Computed Tomography
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Jonsson Comprehensive Cancer Center
mCRPC
AXT-1003 Combination With Enzalutamide in Participants With mCRPC
The purpose of this study is to evaluate the efficacy, and safety of AXT-1003 combined with Enzalutamide in subjects with advanced prostate cancer.
- Trial name
- NCT07897071
- Testing
- AXT-1003, Enzalutamide
- Where
- 4 sites in China
- Volunteers
- 105 people
- Sponsor
- Axter Therapeutics (Beijing) Co., Ltd
Prostate Cancer, Prostate Adenocarcinoma
Two-Fraction Ultrahypofractionated Radiotherapy With Focal Boost for Intermediate Risk, Localized Prostate Cancer
The goal of this clinical trial is to assess the non-inferiority irradiating low and intermediate risk, localized prostate cancer in two fractions of radiotherapy, compared to five fractions of radiotherapy which is the standard…
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Localized Prostate Carcinoma
- Trial name
- TURBO (NCT06518226)
- Testing
- Ultrahypofractionated MRgRT in 2 fractions, Standard of care: MRgRT in 5 fractions
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- UMC Utrecht
Prostate Cancer
Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer
This study assess the Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients with Newly-Diagnosed High-Risk or Very-High-Risk Prostate Cancer
- Trial name
- NCT06122584
- Testing
- [18F]PSMA-1007
- Where
- 19 sites in France, Germany and 4 more
- Volunteers
- 434 people
- Sponsor
- ABX advanced biochemical compounds GmbH
Prostate Cancer, Breast Cancer
Collection of Blood From Patients With Cancer
This study will collect blood from patients with cancer to study the level of cells which decrease the immune response (suppressor cells) before and after chemotherapy.
- Conditions
- Prostate Cancer, Breast Cancer, Colon Cancer, Lung Cancer
- Trial name
- NCT00034216
- Where
- United States
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer, Prostate Cancer Patients Treated by Radiotherapy
Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer
This study is for adult men with previously untreated high risk, very high risk, or pelvic lymph node positive prostate cancer. The purpose of this study is to evaluate the safety and effectiveness of the combination of two…
- Trial name
- NCT07325721
- Testing
- Hypofractionated radiation with a microboost
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Medical University of South Carolina
Prostate Cancer
Immediate Curative vs Conservative Treatment in Older Men With M0, High-risk Prostate Cancer
It is currently unclear if immediate curative treatment (radiotherapy or surgery) of high-risk prostate cancer without metastasis in older men (>=75 years) generates the same survival benefits as in younger patients or if the…
- Trial name
- GrandP/SPCG19 (NCT05448547)
- Testing
- Radiotherapy or surgery, initial observation, Hormone therapy
- Where
- 26 sites in Denmark, Finland and 2 more
- Volunteers
- 980 people, healthy volunteers welcome
- Sponsor
- Sven Löffeler
Prostate Cancer
Propranolol Combined With Novel Endocrine Therapy and Androgen Deprivation Therapy (ADT) for Neoadjuvant Treatment in High-Risk Prostate Cancer Patients: A Multicenter, Single-Arm Clinical Study
Propranolol, a non-selective adrenergic beta-receptor blocker, is conventionally used to treat arrhythmias. However, recent studies have demonstrated its therapeutic efficacy in breast cancer, prostate cancer, neonatal…
- Trial name
- NCT07311915
- Testing
- Propranolol combined with novel endocrine therapy and androgen deprivation therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhongda Hospital
Metastatic Castration-resistant Prostate Cancer
Phase II Trial of Zanzalitinib in Patients With Metastatic Castration Resistant Prostate Cancer
This research study is for people with metastatic castrate-resistant prostate cancer (mCRPC). Zanzalintinib is a new drug that shows activity in mCRPC with soft tissue or visceral metastases who have progressed on prior…
- Trial name
- NCT07608718
- Testing
- Zanzalintinib
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Pedro Barata, MD, MSc
Castration Sensitive Prostate Cancer
A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
The goal of this clinical trial is to assess the feasibility of adding a combination of metformin and turmeric as part of a nutritional intervention regimen to the current standard of care, namely, intermittent Androgen…
- Trial name
- NCT06044025
- Testing
- Metformin, Turmeric
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Arkansas