Clinical trials: Patients in ICU
Massage, Heart Failure
Effect of Massage Therapy on Fatigue and Sleep Quality in Patients With Heart Failure in Intensive Care Unit
The purpose of this study was to explore the effect of massage therapy on fatigue and sleep quality in patients with heart failure in the intensive care unit.
- Trial name
- NCT05366673
- Testing
- massage
- Where
- Taiwan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Polytrauma
Comparing Trauma Severity Scores Injury Severity Score "ISS", Rapid Emergency Medicine Score "REMS" and Kampala Trauma Score "KTS"
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.Despite improvements in trauma systems worldwide, trauma continues to be one of the leading…
- Trial name
- NCT05544773
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Assiut University
Coronavirus Infections, COVID-19
Outcomes of Patients With COVID-19 in the Intensive Care Unit
The objective of this study is to evaluate the clinical characteristics and outcomes of critically ill patients with COVID-19 admitted to the intensive care unit. A Multicenter Observational Study.
- Conditions
- Coronavirus Infections, COVID-19, Viral Pneumonia Human Coronavirus
- Trial name
- MexCOVID-19 (NCT04336345)
- Where
- 2 sites in Mexico
- Volunteers
- 150 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Acute Respiratory Failure, Intubation
Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU
Tracheal intubation in the intensive care unit (ICU) is associated with high incidence of difficult intubation and complications.
- Conditions
- Acute Respiratory Failure, Intubation, Intubation; Difficult or Failed, Videolaryngoscopy
- Trial name
- INVIBLADE (NCT06322719)
- Testing
- Hyperangulated blade videolaryngoscope, Macintosh blade videolaryngoscope
- Where
- 29 sites in Spain
- Volunteers
- 1,036 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Weaning from Mechanical Ventilation
Impact of Gamma-OH on Sleep in ICU Patients
The Main objective of the trial is to assess sleep quality with Gamma-OH® in patients difficult to wean from mechanical ventilation in the ICU.
- Trial name
- GO-SLEEP (NCT04224246)
- Testing
- Gamma Hydroxybutyrate
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Poitiers University Hospital
Hyperoxia / High FiO₂ Exposure, Uric Acid/Albumin Ratio (UAR)
Association Between Early FiO₂ Exposure and Changes in the Uric Acid/Albumin Ratio in Septic ICU Patients
This prospective, non-interventional study aims to investigate the relationship between early oxygen exposure and oxidative stress in adult intensive care unit (ICU) patients diagnosed with sepsis or septic shock.
- Trial name
- NCT07332637
- Testing
- Oxygen Exposure (Fraction of Inspired Oxygen, FiO₂) - Standard of Care (Observational, No Experimental Intervention)
- Volunteers
- 110 people
- Sponsor
- Istinye University
Shock, Peripheral Venous Catheterization
Pulse Study: Peripheral Use of Low-dose Vasopressors for Safety and Efficacy in the Intensive Care Unit
Using medications to increase blood pressure, called vasopressors, is invaluable in treating patients who have difficulty maintaining stable blood pressure.
- Conditions
- Shock, Peripheral Venous Catheterization, Central Venous Catheterization, Critically Ill Patients Admitted in ICU
- Trial name
- PULSE (NCT06920173)
- Testing
- Experiemental: Peripheral Venous Catheter
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Kingston Health Sciences Centre
Delirium, Sleep Perception
Effect of Daily Interruption of Continuous Sedation on Delirium, Sleep Perception in Intensive Care Unit (ICU) Patients
This is an intervention study whose purpose is to determine whether daily interruption of sedative infusion contributes to the reduction of the occurrence of delirium and improves sleep perception in critically ill patients.
- Trial name
- ICUDelirium (NCT00714194)
- Testing
- Normal continuous sedation, Daily interruption of continuous sedation
- Where
- Puerto Rico
- Volunteers
- 52 people
- Sponsor
- University of California, San Francisco
Brain Injury, Consciousness Disorders
Early Stepping Verticalization in ICU for ABI Patients
Verticalization was reported to improve the level of arousal and awareness in patients with severe acquired brain injury (ABI) and to be safe in ICU.
- Trial name
- NCT02828371
- Testing
- stepping verticalization, conventional mobilization
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Pediatric Surgical Patients
Evaluation of Preoperative Risk Factors in Children
This study aimed to evaluate preoperative risk factors in pediatric patients and to determine their effectiveness in predicting intensive care unit admission within 72 hours.
- Trial name
- NCT05852899
- Where
- Turkey (Türkiye)
- Volunteers
- 326 people
- Sponsor
- Istanbul University - Cerrahpasa
Critical Illness
A Trial of Enteral Colostrum on Intestinal Permeability in Critically Ill Patients
The effects of colostrum on intestinal permeability in critical ill patients has not been investigated. In current trial, intensive care unit patients with enteral feeding will receive either enteral colostrum or maltodextrin as…
- Trial name
- NCT03186716
- Testing
- Colostrum, Maltodextrin
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- National Nutrition and Food Technology Institute
Critically Ill Patients With a Predicted Prolonged ICU Stay
NMES in Critically Ill Patients
Critically ill patients with a predicted prolonged ICU stay will receive neuromuscular electrical stimulation (NMES) of one quadriceps muscle.
- Trial name
- NESCI (NCT02133300)
- Testing
- electrical stimulation
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- KU Leuven
Renal Failure, Bacterial Infections
Study of Ceftazidime-Avibactam Blood Concentrations in Intensive Care Unit Patients With Renal Failure Requiring Continuous Dialysis
The study's primary objective is to determine plasma and dialysis fluid concentrations in patients prescribed ceftazidime-avibactam as the standard treatment for their infection and requiring continuous venovenous…
- Conditions
- Renal Failure, Bacterial Infections, Critical Illness
- Trial name
- NCT03243864
- Testing
- Ceftazidime-avibactam
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Temple University
Delirium
Dexmedetomidine to Lessen Intensive Care Unit (ICU) Agitation
The primary aim of the DahLIA trial is to determine, in patients with ICU-associated delirium and agitation who are otherwise pathophysiologically stable (as defined), the number of ventilator-free hours in the incident ICU…
- Trial name
- DahLIA (NCT01151865)
- Testing
- Dexmedetomidine
- Where
- 7 sites in Australia
- Volunteers
- 96 people
- Sponsor
- Austin Health
Delirium
Assessment of Postoperative Delirium With CAM ICU Score in Patients Treated With Serotoninergic Reuptake (SSRI) Inhibitors and Undergoing Intervention of Heart Surgery on Pump
The study aims to observe the presence of postoperative delirium in patients undergoing elective cardiac surgery, without changing the pharmacological prescriptions of the enrolled patients and the procedures carried out by…
- Trial name
- DeCAMS-ON (NCT05089097)
- Testing
- evaluation of delirium with CAM-ICU Score
- Where
- Italy
- Volunteers
- 152 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
High Bleeding Risk, Hemorrhage
Efficacy of Intermittent Pneumatic Compression (IPC) on Venous Thromboembolism Incidence in Intensive Care Unit (ICU) Patients With High Bleeding Risk
This multicentre open-label randomized parallel-group trial aims to evaluate the association intermittent pneumatic compression + elastick stockings versus elasting stockings alone on symptomatic or asymptomatic venous…
- Trial name
- CIREA1 (NCT00740844)
- Testing
- Intermittent pneumatic compression of the lower limbs
- Where
- 10 sites in France
- Volunteers
- 408 people
- Sponsor
- University Hospital, Brest
Bronchial Aspiration
Prevention of Broncho-aspiration (BA) in Adult Subjects During Their ICU Stay
Patients of age >18 yo, admitted to the ICU through the surgery department from 2AUG2021 to 1AUG2022 will be divided into three groups: 1.
- Trial name
- NCT05284084
- Testing
- Bed Head elevation, H2 blockers and mouth wash, Data collection for comparison
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Marshall University
PHYSICAL ACTIVITY
Relationship of Physical Condition and Functionality in Post-covid Patients
Cross-sectional, correlational cohort study where the variables Aerobic endurance (6-minute walk test), Muscle endurance (Medical research council MRC), Flexibility (Sit-and-reach test), Functionality (WHODAS 2.0), Number of days…
- Trial name
- NCT05422950
- Testing
- Relationship between physical condition and functionality in post-covid patients
- Where
- Colombia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Respiratory Failure, Intensive Care Pediatric
The Effect of Music Therapy on Vital Signs and Heart Rate Variability of Pediatric Patients During the Extubation Process.
The extubation process is critical to the future health outcomes of the pediatric patient because it tests the ability of the respiratory system to function without the support of mechanical ventilation.
- Trial name
- NCT06591533
- Testing
- Music therapy + standard care, Standard Care (in control arm)
- Where
- 2 sites in Colombia
- Volunteers
- 82 people
- Sponsor
- Claudia Aristizábal
Sleep Disturbance
Impact of a Multifaceted Intervention of Environment Control in the ICU to Optimize Quantity and Quality of Sleep
In critically ill patients, sleep and circadian rhythms are markedly disturbed, including sleep deprivation and disruption, as well as altered sleep architecture, and loss of normal oscillations of Melatonin and Cortisol.
- Trial name
- NCT05694052
- Testing
- Multifaceted Intervention of environment control
- Where
- Chile
- Volunteers
- 56 people
- Sponsor
- Pontificia Universidad Catolica de Chile