Clinical trials: Patients with Multiple Sclerosis
Multiple Sclerosis
Effectiveness of the EXOPULSE Mollii Ⓡ Suit in Patients With Multiple Sclerosis
Abstract: Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with unknown etiology, causing a variety of symptoms including impaired balance, coordination, and…
- Trial name
- NCT06384729
- Testing
- EXOPULSE Mollii Ⓡ
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Universidad Europea de Madrid
Multiple Sclerosis, Vitamin D Deficiency
Safety and Immunologic Effect of Low Dose Versus High Dose Vitamin D3 in Multiple Sclerosis
The purpose of this study is to determine the safety and the immunologic effects of supplementation with low-dose and high-dose cholecalciferol (vitamin D3) in patients with multiple sclerosis.
- Trial name
- NCT01024777
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Muscle Spasticity, Multiple Sclerosis
Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients
The purpose of this study is to determine if Xeomin® will prove effective for significantly improving lower extremity spasticity and will be well tolerated by the majority of MS patients.
- Trial name
- NCT01968902
- Testing
- incabotulinumtoxinA
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Multiple Sclerosis Center of Northeastern New York
Multiple Sclerosis
Improving Memory in Patients With Multiple Sclerosis
People with multiple sclerosis (MS) suffer from cognitive and other brain problems. This study will examine the effectiveness of the drug donepezil and of sugar water for enhancing memory in individuals with MS.
- Trial name
- NCT00062972
- Testing
- donepezil, glucose
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Multiple Sclerosis
Tolerability of Rebif® (Interferon-beta 1-A) Therapy in Korean Patients With Multiple Sclerosis
This is an observational study to assess the tolerability of Rebif treatment in Korean multiple sclerosis (MS) subjects.
- Trial name
- NCT01074346
- Testing
- Interferon-β-1a
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Relapsing Remitting Multiple Sclerosis
ATX-MS-1467 in Patients With Relapsing Forms of Multiple Sclerosis
Phase 1 study to assess the safety and biological activity of ATX-MS-1467 in patients with relapsing forms of multiple sclerosis.
- Trial name
- NCT01097668
- Testing
- ATX-MS-1467
- Where
- 16 sites in Russia, United Kingdom
- Volunteers
- 43 people
- Sponsor
- Apitope Technology (Bristol) Ltd.
Multiple Sclerosis, West Nile Virus
Investigating Visuo-spatial Abilities and Psychological Effects in West Nile and Multiple Sclerosis Patients with a Focus on a Possible Rehabilitation Protocol
The study aims to investigate visuospatial abilities and psychological outcomes in patients with multiple scleroris (MS) and patients with West Nile virus infection (vWN).
- Trial name
- Visuomind (NCT06640660)
- Testing
- Mindlenses Professional, Conventional rehabilitation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Multiple Sclerosis, Social Cognition
Evaluation and Neural Basis of Communication in Patients With Multiple Sclerosis
Multiple sclerosis (MS) progressively leads to an increasing level of disability. That's why individuals faced with this chronic disease whose progression is unpredictable have to mobilize all their available resources.
- Conditions
- Multiple Sclerosis, Social Cognition, Neuropsychology, Psychological Therory
- Trial name
- COGNISEP (NCT02652013)
- Testing
- cognitive evaluation
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Pôle Saint Hélier
Multiple Sclerosis
The Reliability and Validity of the Functional Reach Test in Patients With Multiple Sclerosis
Loss of limits of stability ability is one of the major components of balance dysfunction in MS. The functional reach test is quick and clinically available tool for assessing limits of stability but reliability and validity of…
- Trial name
- NCT04185688
- Testing
- Functional Reach Test
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Gazi University
Multiple Sclerosis, Performance Enhancement
Effects of DHA in Patients With Multiple Sclerosis
This clinical trial will investigate the effects of combining therapeutic exercise with DHA supplementation in 100 patients with multiple sclerosis using a randomized controlled design.
- Conditions
- Multiple Sclerosis, Performance Enhancement, Supplemental Nutrition Assistance Program Education, Strength Outcomes
- Trial name
- DHAME (NCT07346703)
- Testing
- Docosahexaenoic Acid (DHA) Dietary Supplement, Sunflower Oil
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Multiple Sclerosis, Intermittent Fasting
Intermittent Fasting and Mediterranean Diet in Patient With Multiple Sclerosis
When the literature was reviewed, there is no study in which the effects of intermittent fasting and Mediterranean diet on quality of life, sleep, circadian rhythm and appetite hormones leptin and ghrelin levels in MS patients…
- Trial name
- NCT06546033
- Testing
- application of different types of diet
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Nigde Omer Halisdemir University
Multiple Sclerosis, Secondary Progressive, Multiple Sclerosis, Primary Progressive
Efficacy and Safety of Masitinib in the Treatment of Progressive Multiple Sclerosis
The purpose of this study is to compare the safety and efficacy of masitinib 6 mg/kg/day versus placebo in the treatment of patients with primary progressive multiple sclerosis or relapse-free secondary progressive multiple…
- Conditions
- Multiple Sclerosis, Secondary Progressive, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Relapse Free
- Trial name
- NCT01433497
- Testing
- Masitinib
- Where
- 8 sites in Bulgaria, France and 5 more
- Volunteers
- 656 people
- Sponsor
- AB Science
Multiple Sclerosis, Quality of Life
Territorial Implementation and Evaluation of a Multiple Sclerosis Expert Patient Program
Introduction: Multiple sclerosis (MS) affects about 50,000 people in Spain, so it is essential to implement health interventions that meet their needs and demands.
- Conditions
- Multiple Sclerosis, Quality of Life, Patient Empowerment, Patient Activation
- Trial name
- NCT04988880
- Testing
- Multiple Sclerosis Expert Patient Program of Catalonia
- Where
- 6 sites in Spain
- Volunteers
- 152 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Multiple Sclerosis
Avonex Safety and Tolerability in Chinese Subjects With Relapsing Multiple Sclerosis (MS)
The study is designed to determine the effect of weekly intramuscular (IM) administration of 30 mcg Avonex (interferon beta 1a) on safety parameters and gadolinium (Gd) enhanced and T2-weighted cranial magnetic resonance imaging…
- Trial name
- Avonex China (NCT01181115)
- Testing
- Avonex
- Where
- 10 sites in China
- Volunteers
- 60 people
- Sponsor
- Biogen
Multiple Sclerosis
Aerobic Exercise and Flu-like Symptoms Following Interferon Beta 1a Injections in Patients With Multiple Sclerosis?
The purpose of the present study is to test the hypothesis that aerobic training can reduce flu-like symptoms following interferon beta 1a injections in patients with Multiple Sclerosis.
- Trial name
- NCT02236624
- Testing
- Aerobic exercise
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Multiple Sclerosis, Ataxia
Investigation of the Effects of Local Vibration Applied to Different Regions and Spinal Stabilization Exercises
The aim of this study is to investigate the effects of local vibration application applied to different regions on postural control in addition to spinal stabilization training in ataxic multiple sclerosis (MS) patients.
- Trial name
- NCT05885282
- Testing
- paraspinal vibration, gastrosoleus muscle complex vibration, Control Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Sclerosis, Multiple, MS (Multiple Sclerosis)
EXOPULSE Mollii Suit, Motor Function & Multiple Sclerosis (EXOSEP 2)
The goal of this clinical trial is to demonstrate the improvement of motor functions related symptoms in patients with MS and spasticity using Exopulse Mollii suit stimulation in Multiple Sclerosis patients with spasticity.
- Conditions
- Sclerosis, Multiple, MS (Multiple Sclerosis), Spasticity, Muscle, Spastic
- Trial name
- NCT05857280
- Testing
- EXOPULSE Mollii Suit Stimulation
- Where
- United Arab Emirates
- Volunteers
- 36 people
- Sponsor
- Sheikh Shakhbout Medical City
Pulmonary Fibrosis Secondary to Systemic Sclerosis
QAX576 in Patients With Pulmonary Fibrosis Secondary to Systemic Sclerosis
This study will evaluate the safety, tolerability, and mechanism of action of multiple doses of QAX576 in patients with pulmonary fibrosis secondary to systemic sclerosis
- Trial name
- NCT00581997
- Testing
- QAX576
- Volunteers
- 8 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis (MS), Relapsing Remitting Multiple Sclerosis
Assessment of ANK-700 in Patients With Relapsing Remitting Multiple Sclerosis
A safety study of ANK-700 in patients with relapsing remitting multiple sclerosis. The study has two parts: Part A - first in human study in which patients receive a single dose of ANK-700 Part B - patients will receive three…
- Trial name
- MoveS-it (NCT04602390)
- Testing
- ANK-700
- Where
- 15 sites in United States
- Volunteers
- 34 people
- Sponsor
- Anokion SA
Renal Angiomyolipoma
A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)
The purpose of this prospective study is to assess the safety and efficacy of everolimus in Taiwanese patients with renal angiomyolipoma (AML) associated with tuberous sclerosis complex (TSC) .
- Trial name
- NCT05252585
- Testing
- Everolimus
- Where
- 4 sites in Taiwan
- Volunteers
- 4 people
- Sponsor
- Novartis Pharmaceuticals
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