Clinical trials: Patients with Multiple Sclerosis
Bladder Dysfunction, Multiple Sclerosis
Efficacy of Clean Intermittent Catheterization (CIC) in Multiple Sclerosis (MS) Patients With Bladder Dysfunction
The aims of this prospective, randomized study are: To assess the effect of clean intermittent catheterization (CIC) To investigate if MS patients will have symptom reduction (urgency, frequency, nocturia and incontinence) when…
- Trial name
- NCT00913510
- Testing
- CIC using LoFric Primo, Anticholinergic medication
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 24 people
- Sponsor
- Wellspect HealthCare
Demyelinating Diseases of the Central Nervous System (DDC)
Demyelinating Diseases of the Central Nervous System Registry for Patients With Traditional Chinese Medicine (DATE-TCM)
Demyelinating Diseases of the Central Nervous System Registry for Patients with Traditional Chinese Medicine (DATE-TCM) is an observational study aiming to better define the multidimensional (epidemiologic, demographic and…
- Trial name
- NCT05415579
- Testing
- Traditional Chinese medicine (TCM)
- Volunteers
- 2,000 people
- Sponsor
- Dongzhimen Hospital, Beijing
Relapsing Multiple Sclerosis
Transition to Peginterferon Beta-1a (BIIB017) From Subcutaneous Interferon Therapy
The primary objective of the study is to evaluate, in participants with RMS, safety and tolerability (as defined by the frequency of adverse events [AEs] of flu-like symptoms [FLS; chills, pyrexia, myalgia, and asthenia]…
- Trial name
- Frequency (NCT02234869)
- Testing
- Interferon Beta, BIIB017 (Peginterferon beta-1a)
- Sponsor
- Biogen
Multiple Sclerosis
Pharmacodynamic Study to Better Understand the Therapeutic Response and Immunomodulatory Effects of Avonex in Multiple Sclerosis (MS) Patients and Healthy Volunteers
This study will look at differences in bioanalytical measures among different groups of MS patients and Healthy Volunteers, when administered interferon beta-1a.
- Trial name
- NCT00913666
- Testing
- Interferon beta-1a (Avonex)
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Biogen
Multiple Sclerosis
Safety and Tolerability of Fingolimod in Patients With Relapsing-remitting Multiple Sclerosis
This 4 month, open-label study will evaluate the safety and tolerability of fingolimod 0.5 mg in patients with relapsing-remitting multiple sclerosis (RRMS) and generate additional data in Multiple Sclerosis (MS) patient…
- Trial name
- NCT01497262
- Testing
- Fingolimod
- Where
- 29 sites in Argentina, Brazil and 6 more
- Volunteers
- 162 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis
Motivation of Patients Diagnosed With Multiple Sclerosis to Become Citizen Researchers
The study will based on qualitative methods investigate motivational factors among patients diagnosed with multiple sclerosis for registering nutrition, environmental factors, stress provoking factors and physical activity…
- Trial name
- NCT02760082
- Testing
- Qualitative evaluation
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- University of Copenhagen
Multiple Sclerosis
The Effect of Hybrid Telerehabilitation-Based Structured Exercise Programs in Patients With Multiple Sclerosis
The aim of our study is to compare the effects of hybrid telerehabilitation (TR)-based exercise program applied in patients with MS, only TR-based exercise program and only clinical-based exercise program on walking speed…
- Trial name
- NCT06293079
- Testing
- Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Biruni University
Multiple Sclerosis
Physical Telerehabilitation in Multiple Sclerosis
The study aims to evaluate the efficacy of the MS HAT (Multiple Sclerosis Home Automated Telemanagement) System as an adjunct to the current standard of medical care for patients with MS (PwMS).
- Trial name
- NCT03230903
- Testing
- Home telerehabilitation, Usual Care
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Columbia University
Multiple Sclerosis
Clinical Factors Associated With Position Sense in Patients With Multiple Sclerosis
Sensory impairment is an important problem for patients with Multiple Sclerosis (MS). Although there is no complete loss of sensation in patients, 80% of patients have a significant sensory impairment.
- Trial name
- NCT04548297
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Gazi University
Multiple Sclerosis
Effects of Immersive Virtual Reality on Balance, Mobility, and Fatigue in Patients With Multiple Sclerosis
Gait disorder, imbalance, and fatigue are the most frequently reported complaints in Multiple Sclerosis (MS), a chronic neurodegenerative disease.
- Trial name
- NCT03501342
- Testing
- Virtual reality group, Dynamic Balance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Gazi University
Multiple Sclerosis, Spasticity
Classification of Upper and Lower Limb Spasticity Patterns and Their Impact on Quality of Life in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic neurological disease frequently associated with spasticity, which may lead to functional limitations and reduced quality of life.
- Conditions
- Multiple Sclerosis, Spasticity, Spasticity With Multiple Sclerosis
- Trial name
- NCT07466823
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Marmara University
Relapsing-remitting Multiple Sclerosis
Efficacy and Safety of BCD-063 and Copaxone-Teva in Patients With Relapsing-Remitting Multiple Sclerosis
The objective of the clinical study of the medicinal product for medical use: to compare efficacy and safety of the generic drug BCD-063 and Copaxone®-Teva in patients with relapsing-remitting multiple sclerosis.
- Trial name
- NCT02753088
- Testing
- BCD-063, Copaxone-Teva
- Volunteers
- 158 people
- Sponsor
- Biocad
Secondary Progressive Multiple Sclerosis
Open-Label Study to Evaluate the Efficacy of ECP in Secondary Progressive Multiple Sclerosis
In this research study, the investigators will determine whether a procedure called Extracorporeal Photopheresis (ECP) is helpful in preventing progression of disability in people with SPMS when compared to monthly corticosteroid…
- Trial name
- MSECP (NCT02296346)
- Testing
- SoluMedrol, Extracorporeal Photopheresis
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Utah
Aromatherapy, Randomized Controlled Trial
Aromatherapy With Lavender Essential Oil in Patients With Multiple Sclerosis
The study was conducted with patients with Multiple Sclerosis (MS) who applied to the Neurology Outpatient Clinic of Atatürk University Research Hospital, met the inclusion criteria and agreed to participate in the study.
- Conditions
- Aromatherapy, Randomized Controlled Trial, Multiple Sclerosis
- Trial name
- NCT05929638
- Testing
- lavender oil
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Multiple Sclerosis
Clinical Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Ponesimod in Patients With Relapsing-remitting Multiple Sclerosis
This study is an extension to the study AC-058B201 and will investigate the long-term safety, tolerability and efficacy of ponesimod in patients with relapsing-remitting multiple sclerosis.
- Trial name
- NCT01093326
- Testing
- Ponesimod 10 mg, Ponesimod 20 mg, Ponesimod 40 mg
- Where
- 71 sites in United States, Austria and 18 more
- Volunteers
- 353 people
- Sponsor
- Actelion
Multiple Sclerosis
Physical Disability in Patients Treated With Betaferon
To gather Observation data about physical disability progression, safety and adherence during the use of Betaferon in daily practice.
- Trial name
- NCT00873340
- Testing
- Interferon-1beta (Betaseron, BAY86-5046)
- Where
- Colombia
- Volunteers
- 83 people
- Sponsor
- Bayer
Amyotrophic Lateral Sclerosis (ALS), Parkinson Disease (PD)
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
This is a Phase 1/2 study to evaluate the safety and tolerability of 18F-OP-801 in subjects with ALS, AD, MS, PD and age-matched HVs.
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Parkinson Disease (PD), Alzheimer Disease (AD), Multiple Sclerosis (MS)
- Trial name
- NCT05395624
- Testing
- 18F-OP-801
- Where
- 3 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ashvattha Therapeutics, Inc.
Multiple Sclerosis
Exploratory Study to Investigate the Reparative and Regenerative Potential of Alemtuzumab in Relapsing-Remitting Multiple Sclerosis Patients Participating in the CARE MS I and MS II Studies
The primary goal of this study will be to explore the reparative and regenerative potential of alemtuzumab in RRMS patients who are participating in the CARE MS I and CARE MS II studies using conventional and non-conventional MRI…
- Trial name
- NCT01020370
- Sponsor
- Wayne State University
Multiple Sclerosis
Fecal Microbiota Transplantation After Autologous HSCT in Patients With Multiple Sclerosis
The hypothesis of the study is that according to modern data, the pathogenesis of multiple sclerosis is inextricably linked to the patient's microbiota.
- Trial name
- NCT04203017
- Testing
- allogeneic fecal microbiota
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Autoimmune Diseases, Non-small Cell Lung Cancer
Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease
The purpose of this study is to explore the safety, tolerability and activity of Nivolumab, a PD-1 inhibitor, in cohorts of patients with autoimmune disease.
- Conditions
- Autoimmune Diseases, Non-small Cell Lung Cancer, Rheumatoid Arthritis, Psoriasis
- Trial name
- NCT03656627
- Testing
- Nivolumab
- Where
- 9 sites in United States
- Volunteers
- 7 people
- Sponsor
- Alliance Foundation Trials, LLC.
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