Clinical trials: Pediatric Chronic Pain
Pain
Pharmacogenetic Morphine Spine Study
The purpose of this research study is to identify factors and genes (the DNA material that determines the makeup of the human body) that may be associated with how children cope with pain and respond to pain medication.
- Trial name
- NCT01839461
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Amplified Musculoskeletal Pain Syndrome (AMPS)
Efficacy and Safety of Nerivio for the Management of Amplified Musculoskeletal Pain Syndrome in Pediatric Patients
The goal of this trial is to learn how the Nerivio® device works to treat Amplified Musculoskeletal Pain Syndrome (AMPS) in children ages 8-18. Nerivio® is a wearable device that activates specific nerves in the upper arm.
- Trial name
- Nerivio (NCT07249931)
- Testing
- Nerivio(R) Device, Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Health
Gastrointestinal Disorders, Functional
Web-based Management of Pediatric Functional Abdominal Pain
Functional abdominal pain (FAP), a pediatric pain condition without significant organic pathology, is a precursor to chronic pain and high healthcare utilization in young adulthood.
- Trial name
- NCT02327377
- Testing
- Online Cognitive Behavior Therapy, Online Education
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Pain, Chronic Pain Syndrome
Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents
The goal of this clinical trial is to learn if adding Shiatsu therapy to standard treatment can improve quality of life in children and adolescents with chronic pain that is not caused by inflammation.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain and Comorbid Emotional Problems, Chronic Pain, Psychogenic
- Trial name
- ShiQoL (NCT06929598)
- Testing
- Shiatsu Therapy
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Tel Aviv University
Pediatric Chronic Pain
Pediatric Pain Rehabilitation Program
The purpose of this study is to describe the demographic, medical, and psychological/behavioral characteristics of children and adolescent patients admitted to the Cleveland Clinic Children's Hospital's Pain Rehabilitation…
- Trial name
- NCT01340261
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 975 people
- Sponsor
- The Cleveland Clinic
Pain, Chronic, Pain
SPRINT: Signature for Pain Recovery IN Teens
To identify biological and phenotypic prognostic markers of recovery vs. persistence of pain and functional disability in adolescents with chronic musculoskeletal pain.
- Conditions
- Pain, Chronic, Pain, Joint Pain, Musculoskeletal Pain
- Trial name
- SPRINT (NCT04285112)
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University
Chronic Pain
Effectiveness, Safety, and Tolerability Study of Oxymorphone Immediate Release (IR) Oral Liquid in Opioid Tolerant Pediatric Subjects
The purpose of this study is to evaluate the effectiveness, tolerability, and safety of oxymorphone immediate release (IR) oral liquid as an analgesic in pediatric subjects having severe to moderate chronic pain.
- Trial name
- NCT01206907
- Testing
- oxymorphone IR
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Primary Headache Disorder
Feasibility of a Developmentally-tailored Mobile App for Tracking Mood and Pain in Children With Migraine
This study aims to inform the continued development of a mobile app intended to support the treatment of CYP with migraine. After extensive public and patient involvement, Happyr Health has developed a mobile app that allows…
- Trial name
- NCT05337930
- Testing
- Happyr App
- Where
- United Kingdom
- Sponsor
- Happyr Ltd
Chronic Pain
Ketamine in Chronic Kid's (KiCK) Pain
This study is designed to select the most tolerable dose of oral ketamine for children with chronic pain. Children will be given either placebo or one of three dosages of oral ketamine for 2 weeks.
- Trial name
- KiCK Pain (NCT01755169)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Medical University of South Carolina
Chronic Pain, Pediatric Disorder
PET/MRI in the Diagnosis of Pediatric Chronic Pain
[18F]FTC-146 is a sigma-1 receptor detector and is an experimental radiotracer. Several studies have implicated involvement of sigma-1 receptors in generation and perpetuation of chronic pain conditions, while others are…
- Conditions
- Chronic Pain, Pediatric Disorder, Neuropathic Pain, Nociceptive Pain
- Trial name
- NCT04435821
- Testing
- [18F]FTC-146
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Obesity, Adolescent, Pain, Chronic
Pain and Weight Treatment: Development and Trial of PAW
Pediatric weight management efficacy is impacted by failure to complete treatment protocols and, for those that do complete treatment, a return to unhealthy behaviors.
- Conditions
- Obesity, Adolescent, Pain, Chronic, CBT
- Trial name
- PAW (NCT04046562)
- Testing
- PAW, Pain Education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Connecticut Children's Medical Center
Chronic Pain
A Study to Assess the Safety and Effectiveness of Durogesic (Fentanyl Transdermal Patch) in the Treatment of Children With Chronic Pain Requiring Long-term Narcotic Pain Relief Therapy
The purpose of this study is to assess the effectiveness and safety of Durogesic® (a transdermal patch delivering the narcotic pain-reliever fentanyl) in the treatment of children with chronic pain requiring long-term narcotic…
- Trial name
- NCT00271453
- Testing
- Durogesic® (fentanyl transdermal drug delivery system)
- Volunteers
- 41 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Endoscopy in Chronic Abdominal Pain
Diagnostic Yeild of Esophagogastrodudenoscopy in Pediatric Chronic Abdominal Pain
Evaluate the diagnostic yeild of esophagogastrodudenoscopy in children with chronic abdominal pain
- Trial name
- NCT07154940
- Volunteers
- 100 people
- Sponsor
- Assiut University
Chronic Pain, Postoperative Pain
Epidemiological Study of Post-operative Chronic Pediatric Pain.
This study aims to estimate prevalence and determine risk factors for chronic pain at 3 months post-operative in pediatric surgery.
- Trial name
- PEDIACHRO (NCT04068350)
- Testing
- Pain questionnaire
- Volunteers
- 582 people
- Sponsor
- University Hospital, Bordeaux
Pediatric Chronic Neuropathic Pain
Gabapentin and Oxcarbazepine for Chronic Neuropathic Pain in Children and Adolescents: A Clinical Effectiveness Study
Given the widespread use of anticonvulsants in the pediatric chronic pain population and the absence of scientific data supporting their use, the investigators propose a randomized, double blind, two group parallel design in…
- Trial name
- NCT02219373
- Testing
- Gabapentin, Oxcarbazepine
- Where
- United States
- Sponsor
- Boston Children's Hospital
Amplified Musculoskeletal Pain Syndrome, Reflex Sympathetic Dystrophy
Audio-Visual Relaxation Technology for Pediatric Amplified Musculoskeletal Pain Syndrome
A pilot randomized controlled trial to assess feasibility, acceptability and generate outcome domains for a future RCT testing the efficacy of immersive virtual reality on pain intensity in pediatric amplified musculoskeletal…
- Conditions
- Amplified Musculoskeletal Pain Syndrome, Reflex Sympathetic Dystrophy, Complex Regional Pain Syndromes
- Trial name
- NCT03762213
- Testing
- Oculus GO VR HMD, application Happy Place (© Mimerse), iPad, application Happy Place (© Mimerse)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center
Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
Do Biomarkers Predict Response to a Pediatric Chronic Pain Symptom Management Program?
The purpose of this study is find out if we can use simple tests (biomarkers) to tell us if a specific child would benefit most from CBT or from the low FODMAPs diet.
- Conditions
- Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders, Functional Bowel Disorder
- Trial name
- NCT03823742
- Testing
- Cognitive Behavioral Therapy, Low FODMAP Diet
- Where
- 2 sites in United States
- Volunteers
- 163 people
- Sponsor
- Baylor College of Medicine
Pediatric Gastrointestinal Disorders, Chronic Abdominal Pain in Children
Role and Diagnostic Yield of Upper Endoscopy in Children With Chronic Abdominal Pain
Chronic abdominal pain is a common problem in children and may be caused by functional or organic gastrointestinal disorders. While many children have no identifiable structural disease, some may have conditions that can be…
- Conditions
- Pediatric Gastrointestinal Disorders, Chronic Abdominal Pain in Children, Upper Endoscopy
- Trial name
- UGI-CAP (NCT07372976)
- Testing
- Upper Gastrointestinal Endoscopy
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Assiut University
Chronic Abdominal Pain, Chronic Diarrhea
Evaluation of Fecal Calprotectin Screening and a Gastroenterology Questionnaire for Triaging Children With Chronic Abdominal Pain and/or Diarrhea Referred to a Pediatric Gastroenterology Service
Triaging new pediatric gastroenterology consultations is challenging as both inflammatory and non-inflammatory gastrointestinal (GI) diseases can present with non-specific chronic abdominal pain and/or diarrhea.
- Trial name
- NCT01866774
- Testing
- Fecal calprotectin level
- Where
- 2 sites in Canada
- Volunteers
- 15 people
- Sponsor
- Queen's University
Chronic Pain
Ready for Change: Enhancing Motivational Engagement Prior to IIPT
This is a randomized, motivational-interviewing-based intervention to improve readiness-to-change, or willingness to engage in a self-management approach to chronic pain, for patients referred to our intensive interdisciplinary…
- Trial name
- PREPaRe (NCT04093921)
- Testing
- MET-based therapy, Standard Care
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Boston Children's Hospital