Clinical trials: Pediatric Critical Illness
Iatrogenic Anaemia
The Influence of Blood Sampling Technique on the Total Amount of Blood Collected for Laboratory Testing Critically Ill Pediatric Patients
The aim of this prospective randomized study is to evaluate blood loss caused by laboratory blood draws in patients in the paediatric ICU (Intensive Care Unit) of a tertiary hospital among two groups of patients with established…
- Trial name
- PEDPBM (NCT06376747)
- Testing
- In line sampling, Standard blood sampling technique
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Critical Illness Polyneuropathy
Evaluation of Pediatric Critical Illness Neuropathy/Myopathy in Pediatric Intensive Care Unit
Intensive Care Unit Acquired Weakness(ICUAW) encompasses a spectrum of disorders characterized by generalized weakness developing after the onset of critical illness.
- Trial name
- NCT02763709
- Where
- India
- Volunteers
- 97 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pediatric, Critical Illness
Sleep After Pediatric Critical Illness
This study tests a pilot educational sleep intervention for children after critical care hospitalization.
- Conditions
- Pediatric, Critical Illness, Sleep Disturbance
- Trial name
- NCT05879640
- Testing
- Sleep education
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Oregon Health and Science University
Critical Illness
Lorazepam Sedation for Critically Ill Children
This clinical trial is being performed under the Best Pharmaceuticals for Children Act, signed into law in 2002 in order to improve pediatric labeling for off-patent drugs.
- Trial name
- NCT00109395
- Testing
- Lorazepam, Midazolam, Lorazepam CI
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- The Emmes Company, LLC
Anesthesia, Surgery
A Review of "Anesthesia Stat!" in the Pediatric Operating Room
The objective of this study is to look at critical events in the pediatric operating room in a retrospective and now prospective fashion to determine if there are any trends such as age, presence of URI, type of surgery, type of…
- Conditions
- Anesthesia, Surgery, Critical Illness, Critical Incident
- Trial name
- NCT03152513
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Wake Forest University Health Sciences
Metabolism and Nutrition Disorder
Prospective Evaluation of the Incidence of PICS
Advances in modern medicine and critical care interventions have greatly impacted survival of critically ill patients, but these interventions are not without consequences.
- Trial name
- ProsPICS (NCT03584399)
- Testing
- PICS in critically ill pediatric population
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Emergencies, Cardiopulmonary Arrest
Simulation Trial of Telemedical Support for Paramedics
In the United States, the current standard of prehospital (i.e. outside of hospitals) emergency care for children with life-threatening illnesses in the community includes remote physician support for paramedics providing…
- Conditions
- Emergencies, Cardiopulmonary Arrest, Acute Respiratory Failure, Status Epilepticus
- Trial name
- R01 (NCT06441760)
- Testing
- Video teleconsultation, Audio support
- Where
- 9 sites in United States
- Volunteers
- 420 people
- Sponsor
- Boston Medical Center
Critical Illness, Multiple Organ Dysfunction Syndrome
pSOFA Score in Predicting Mortality in Pediatric Intensive Care
This prospective observational cohort study aims to evaluate the predictive performance of the Pediatric Sequential Organ Failure Assessment (pSOFA) score for mortality and selected clinical outcomes among critically ill children…
- Trial name
- NCT07858487
- Volunteers
- 121 people
- Sponsor
- Assiut University
Family Members of: Newborns Extremely Premature, Family Members of: New Pediatric Oncology Patients
Impact of Serious Pediatric Illness on Parent and Sibling Health
To estimate the impact of having a child with serious illness (SI) on the health and healthcare of other members of the child's family.
- Conditions
- Family Members of: Newborns Extremely Premature, Family Members of: New Pediatric Oncology Patients, Family Members of: Critical Congenital Heart Defect Patients, Family Members of: Children Severe Neurological Impairment
- Trial name
- NCT03971344
- Where
- United States
- Volunteers
- 161,000 people
- Sponsor
- Children's Hospital of Philadelphia
Critical Illness, Neurologic Disorder
The "What Is Important to Us" Communication Intervention Pilot Clinical Trial
The objective of this study is to conduct a pilot randomized controlled trial (RCT) of a photo-narrative communication intervention developed by our study team with patients/parents of children with severe neurological impairment…
- Trial name
- NCT06208332
- Testing
- "What Is Important to Us" Communication Intervention
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Seattle Children's Hospital
Pediatric, Critical Illness
Examining Health Literacy in Biorepository Consents
Previous research has shown that most parents would allow their child's leftover blood to be included in a de-identified biorepository using opt-out consent in an outpatient setting.
- Conditions
- Pediatric, Critical Illness, Consent
- Trial name
- NCT04953169
- Testing
- Biobank Video, Non-Video
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Delirium
Quetiapine Treatment for Pediatric Delirium
This is a prospective, double-blind, randomized controlled trial to begin determining the efficacy of quetiapine as a treatment for pediatric delirium in patients admitted to the pediatric intensive care unit (PICU)
- Trial name
- NCT03572257
- Testing
- Quetiapine
- Where
- United States
- Sponsor
- Medical College of Wisconsin
Sepsis, Critical Illness
Methionine Metabolism in Enterally Fed Pediatric Sepsis
Critically ill children have abnormal utilization of nutrients such as glucose, lipids and protein. Protein synthesis is increased mainly in the form of immune and signaling proteins, while muscle and structural protein synthesis…
- Trial name
- NCT01889264
- Testing
- Observational
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Critical Illness, Pediatric Intensive Care Unit
COPM-Based Goal Setting Strategies in the PICU
COPM-Based Goal Setting Strategies in the PICU
- Trial name
- NCT07128446
- Testing
- Standard physical and occupational therapy
- Where
- 2 sites in South Korea
- Volunteers
- 5 people
- Sponsor
- Samsung Medical Center
Critical Illness
Enhancing Parent/Caregiver Engagement in the Pediatric Intensive Care Unit (PICU): A PICU Journal
Admission to the pediatric intensive care unit (PICU) is well-recognized to be extremely distressing and stressful for the patient and family.
- Trial name
- PICUJournal (NCT06117345)
- Testing
- PICU Journal
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Vanderbilt University Medical Center
Critical Illness, Dysbiosis
Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children
This study evaluates the effects of either Pediasure or Nourish formulas on the gastrointestinal microbiome in critically-ill children. Patients will be randomized to received either Pediasure or Nourish.
- Conditions
- Critical Illness, Dysbiosis, Pediatric ALL
- Trial name
- NCT03414775
- Testing
- Nourish, Pediasure
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pittsburgh
Pediatric Critical Illness, Anxiety
Interactive Digital Art-Based Relaxation Program
This randomized controlled trial aims to evaluate the effects of an Interactive Digital Art-Based Relaxation Program on physiological parameters, anxiety levels, and emotional distress in children aged 7-12 years receiving care…
- Trial name
- NCT07388485
- Testing
- Interactive Digital Art-Based Relaxation Program
- Volunteers
- 60 people
- Sponsor
- Gazi University
Arterial Hypotension, Shock
Cerebral Circulation in Critically Ill Children
The principal purpose of this study is to describe the changes in cerebral circulation (assessed by transcranial ultrasound) and oxygenation (assessed by Near InfraRed spectroscopy, NIRS) during resuscitation for hemodynamic…
- Conditions
- Arterial Hypotension, Shock, Cerebral Lesion
- Trial name
- CIRCU-REAPED (NCT03731104)
- Testing
- Near InfraRed Spectroscopy assessment, Transcranial Doppler Ultrasound assessment, Cardiac output assessment
- Where
- 3 sites in France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Gastrointestinal Injury, Gastrointestinal Failure
Acute Gastrointestinal Injury in Pediatrics
Critically Ill children may develop acute gastrointestinal injury secondary to severe inflammation.
- Conditions
- Acute Gastrointestinal Injury, Gastrointestinal Failure, Critical Illness
- Trial name
- AGI (NCT05315245)
- Testing
- AGI
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Universitas Indonesia
Communication, Critical Illness
Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit
This study aims to improve communication between medical teams, patients, and families in the pediatric cardiac intensive care unit.
- Trial name
- NCT03749330
- Testing
- CICU Team And Loved Ones Communicating (CICU TALC)
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Children's Hospital of Philadelphia