Clinical trials: Pediatric Health
Type2 Diabetes, Type 2 Diabetes Mellitus in Obese
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g.
- Conditions
- Type2 Diabetes, Type 2 Diabetes Mellitus in Obese, Dysglycemia, Microvascular Complications
- Trial name
- Metabrain (NCT05277558)
- Testing
- Observational
- Where
- 2 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Type 1, Behavior, Health
Game-based Pediatric Diabetes Education
The goal of this study is to evaluate the impact of a mobile app video game called Digital Vaccine for Type 1 Diabetes (DVx-T1D)™, proposed as a low-risk, non-invasive, digital therapeutic candidate for behavior change in…
- Trial name
- DVx-T1D (NCT06264258)
- Testing
- DVx-T1D™ app
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Asthma in Children
Community Health Equity Accelerator (CHEA) Pediatric Asthma Intervention
The purpose of this pilot is to initiate an academic-community partnership and launch a multi-level intervention that includes an asthma exposure pathway (an online decision support and resource) and a health Promotora program…
- Trial name
- NCT06507943
- Testing
- Promotora Home Visit
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Overweight, Obesity
Connect 4 Health: An Intervention to Improve Childhood Obesity Outcomes
Health care system (HCS)-based interventions have been limited by their inattention to social and environmental barriers that impede improvement in obesity-related behaviors.
- Trial name
- NCT02124460
- Testing
- Health Coaching
- Where
- United States
- Volunteers
- 721 people
- Sponsor
- Massachusetts General Hospital
Anxiety, Pain
An Innovative Tailored Intervention for Improving Children's Postoperative Recovery (WebTIPS)
The goal of this randomized trial is to examine the effectiveness of a tailored Internet-based Preparation Program (WebTIPS) in reducing anxiety and improving the recovery process in children undergoing surgery.
- Conditions
- Anxiety, Pain, Postoperative Behavior
- Trial name
- WebTIPS (NCT03730259)
- Testing
- Web-based Tailored Intervention Preparation for Surgery
- Where
- 2 sites in United States
- Volunteers
- 1,274 people
- Sponsor
- University of California, Irvine
Heart Failure, Cardiotoxicity
The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial
Pediatric, adolescent and young adult cancer survivors (PAYA-CS) are at higher risk of cardiovascular (CV) morbidity and mortality.
- Conditions
- Heart Failure, Cardiotoxicity, Cancer
- Trial name
- HIMALAYAS (NCT05023785)
- Testing
- Cardio-oncology Rehabilitation (CORE)
- Where
- Canada
- Volunteers
- 336 people
- Sponsor
- University Health Network, Toronto
Pediatric Obesity
Exergaming for Health: Impact of a Community-Based Active Video Gaming Curriculum in Pediatric Weight Management
Evaluation of the effectiveness of Exergaming for Health, a community-based multifaceted weight management program in a randomized controlled trial (RCT). Primary objective: to assess impact of the program on BMI z-scores.
- Trial name
- NCT02436330
- Testing
- Exergaming, Didactic health teaching
- Volunteers
- 84 people
- Sponsor
- University of Illinois Chicago
Weight Change, Body, Behavior, Health
Increased Monitoring of Physical Activity and Calories With Technology
Since severe obesity in youth has been steadily increasing. Specialized pediatric obesity clinics provide programs to aid in reducing obesity.
- Conditions
- Weight Change, Body, Behavior, Health, Obesity, Childhood, Parent-Child Relations
- Trial name
- IMPACT (NCT03961061)
- Testing
- Brenner mFIT (standard care), Brenner mFIT (standard care plus mobile health components)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Health Behavior, Child Obesity
BMI Development and Risk of Overweight and Obesity in Children
The goal of this observational study is to investigate differences in attained BMI and the proportion of overweight/obesity at school entrance in children who attended kindergartens actively delivering a community-based health…
- Conditions
- Health Behavior, Child Obesity, Body Weight
- Trial name
- NCT06097208
- Testing
- community-based health promotion and obesity prevention intervention
- Volunteers
- 3,000 people
- Sponsor
- University of Aarhus
Autism Spectrum Disorder, Obesity
Mobile Health Intervention for Children With Autism
This study is a randomized clinical trial conducted in China from January 2023 to July 2025. It aims to test whether a mobile health program delivered via WeChat, with or without additional human support, can help improve body…
- Conditions
- Autism Spectrum Disorder, Obesity, Pediatric Overweight
- Trial name
- WeChat-Autism (NCT07514910)
- Testing
- Standard Lifestyle Recommendations, WeChat-Based Mobile Health Intervention, Coach-Facilitated Tele-Group Sessions
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Hunan Normal University
SARS-CoV-2, Covid19
COVID-19 Child Health Investigation of Latent Disease in Hamburg
The study measures infection rates and the presence of antibodies for SARS-CoV-2 (COVID-19) among in- and outpatients of all pediatric hospitals, as well as volunteers aged 0 to 18 years in Hamburg, Germany.
- Trial name
- C19CHILD (NCT04534608)
- Where
- Germany
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Perioperative, Children
Pediatric Perioperative Satisfaction Questionnaire
The aim of this study is to develop and validate a self-report questionnaire to evalutate the satisfaction of the children after surgery.
- Conditions
- Perioperative, Children, Satisfaction
- Trial name
- NCT04608968
- Where
- 6 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Juvenile Idiopathic Arthritis
Access to Pediatric Rheumatology Centers for JIA Patients: Factors Associated With Time to Access Pediatric Rheumatology Centers
JIA patients, their parents, and the health care professionals experience the complexity of the initial care pathway. The aim of the study is to explore the referral pathway to access pediatric rheumatology centers for JIA…
- Trial name
- AJILITT (NCT05696340)
- Testing
- semi-structured interview
- Where
- 4 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity, Adolescent
PathMate2: The Impact of Health Information System Services on the Effects of Therapy in Overweight Teenagers
Randomised controlled trial in overweight adolescents using a health App.
- Trial name
- PM2 (NCT03270423)
- Testing
- PathMate2, PathMateS
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Ostschweizer Kinderspital
Mental Health Issue, Inflammatory Bowel Diseases
RxWell in Pediatric IBD for Disease Management and Transition Readiness
Evaluate the feasibility and acceptability of adapted coached RxWell for patients ages 16-25. Adapt and beta test the modified RxWell product to include chronic disease management and transition readiness.
- Trial name
- NCT05461014
- Testing
- dCBI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Pittsburgh
Brain Neoplasms
Health Related Quality of Life in Pediatric Central Nervous System (CNS) Tumors: A Feasibility Study Utilizing PROMIS
In this research study the investigators want to learn more about the quality of life before, during and after cancer treatment in patients with central nervous system brain tumors.
- Trial name
- PROMIS-QOL (NCT02603692)
- Testing
- PROMIS-QOL
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte
Pediatric ACEs Screening and Resiliency Study
Stressful and traumatic experiences in childhood (Adverse Childhood Events, or ACEs) have been associated with poor health outcomes that extend into adulthood.
- Conditions
- Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection
- Trial name
- PEARLS (NCT04182906)
- Testing
- Care Coordination, Resiliency Clinic, Usual Care
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Diet Habit, Pollution; Exposure
Children's Health Study Diet and Air Pollution
This study is built upon the existing data in the Children's Health Study to examine the longitudinal association between childhood exposure to air pollutants and changes in diet among adolescents.
- Conditions
- Diet Habit, Pollution; Exposure, Child Obesity
- Trial name
- CHS DIET (NCT03379298)
- Volunteers
- 3,142 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Otitis Media With Effusion, Acute Otitis Media
Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry
This prospective, single-arm, multicenter registry is being conducted to collect real world post-market data from patients aged from 6 months to 17 years of age who are undergoing an in-office ear tube placement procedure…
- Conditions
- Otitis Media With Effusion, Acute Otitis Media, Otitis Media
- Trial name
- NCT05915078
- Testing
- Iontophoresis and tube placement
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- Smith & Nephew, Inc.
Pediatric Obesity
Health & Culture Project: Cultural Factors Underlying Obesity in African-American Adolescents
The overall goal of this study is to examine the relationships between cultural identity and identity-based motivation, physical activity, diet and obesity risk in African-American adolescents.
- Trial name
- HCP (NCT02938663)
- Testing
- Questionnaires and Measurements
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Michigan