Clinical trials: Pediatric Heart Transplant
Heart Transplantation
Pediatric Heart Transplantation: Transitioning to Adult Care
The purpose of this pilot trial, Transitioning to Adult Care (TRANSIT), is to develop and test an intervention (i.e., a standardized, tailored transition program focused on enhancing adherence) to improve outcomes for emerging…
- Trial name
- TRANSIT (NCT02090257)
- Testing
- TRANSIT
- Where
- 6 sites in United States
- Volunteers
- 88 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Congenital Disorders
Pulmonary Resistance in Fontan Who Have Undergone Heart Transplantation
Clinical evidence reveals that some patients who undergo cardiac transplantation exhibit problems with pulmonary vascular resistance as well.
- Trial name
- NCT00268047
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Children's Healthcare of Atlanta
Heart Transplant Infection Prevention
Safety and Efficacy of Measles, Mumps, Rubella Vaccination in Pediatric Heart Transplantation Patients
The study is an interventional, non-randomized assessment of safety and efficacy of live Measles, Mumps and Rubella (MMR) vaccine in subjects aged 12-months to 17 years who have undergone heart transplantation.
- Trial name
- NCT07195032
- Testing
- Commercial measles, mumps, and rubella (MMR) vaccine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Mercy Hospital Kansas City
Ventricular Dysfunction, Ventricular Dysfunction, Left
Registry to Monitor Berlin Heart EXCOR® Pediatric VAD as a Bridge to Cardiac Transplantation.
The purpose of this post market surveillance is to continue monitoring the safety and effectiveness of the Berlin Heart EXCOR® Pediatric.
- Conditions
- Ventricular Dysfunction, Ventricular Dysfunction, Left, Ventricular Dysfunction, Right
- Trial name
- NCT03701997
- Testing
- EXCOR Pediatric
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Berlin Heart, Inc
Vascular; Change, Dietary Modification
On-Line Intervention to Lower Cardiovascular Risk in Pediatric Heart Transplant Patients
Pediatric heart transplant patients have a high-risk cardiovascular profile affecting their long-term outcomes and survival. Currently, no effective cardiovascular preventative care is provided for this pediatric population, in…
- Conditions
- Vascular; Change, Dietary Modification, Physical Activity, Health Behavior
- Trial name
- NCT02519946
- Testing
- On-Line Diet and Exercise Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Stanford University
Kidney Transplantation, Liver Transplantation
Quality of Life in Pediatric Transplant Recipients
Adherence to medical regimens refers to what degree a patient chooses to follow the advice given by his/her healthcare provider.
- Conditions
- Kidney Transplantation, Liver Transplantation, Heart Transplantation, Lung Transplantation
- Trial name
- NCT00209196
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Emory University
Heart Transplant Infection, Kidney Transplant Infection
CMV T Cell Immunity in Pediatric Solid Organ Transplant Recipients
CMV infection and disease remain a significant clinical challenge for pediatric solid organ transplant (SOT) recipients. Current prevention strategies are limited to prophylaxis in which antiviral medication is administered for a…
- Conditions
- Heart Transplant Infection, Kidney Transplant Infection, Liver Transplant Infection, CMV
- Trial name
- NCT03924219
- Testing
- CMV T cell Immunity Assay
- Where
- 12 sites in United States
- Volunteers
- 161 people
- Sponsor
- Vanderbilt University Medical Center
Congenital Heart Disease
Partial Heart Transplantation
The purpose of this study is to determine if a partial heart transplantation in patients with congenital heart disease is safe and feasible.
- Trial name
- NCT06055556
- Testing
- Partial Heart Transplantation, Freshly procured valve
- Where
- United States
- Sponsor
- Duke University
Dermatitis
Atopic Dermatitis-Like Skin Disease in Pediatric Heart Transplant Patients
The skin disease found in pediatric heart transplant patients represents an atopic dermatitis-like rash that is refractory to systemic immunomodulation.
- Trial name
- NCT00176956
- Testing
- Skin Biopsy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hordinsky, Maria K., MD
Transplant Coronary Artery Disease
Coronary Artery Study in Pediatric Heart Transplantation
Transplant coronary artery disease (TCAD) is a significant cause of morbidity and mortality in pediatric heart transplantation (PHT).
- Trial name
- CAS-POHT (NCT01546870)
- Where
- United States
- Sponsor
- Arkansas Children's Hospital Research Institute
Kidney Transplantation, Liver Transplantation
Quality of Life in Pediatric Transplant Patients
The goal of this study is to compare parent and child perceptions of wellness and vulnerability in children who have undergone solid organ transplant.
- Conditions
- Kidney Transplantation, Liver Transplantation, Heart Transplantation
- Trial name
- NCT00678002
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Medical College of Wisconsin
Cardiac Transplantation
Outcomes in Pediatric Heart Transplant Recipients Receiving Cellcept
The survival of children who have received heart transplants has greatly improved over the last ten years. One reason for this is better control over rejection.
- Trial name
- NCT00166153
- Testing
- Mycophenolate Mofetil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Pediatric Heart Transplantation, Immunosuppression
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
The TEAMMATE Trial will enroll 210 pediatric heart transplant patients from 25 centers at 6 months post-transplant and follow each patient for 2.5 years.
- Conditions
- Pediatric Heart Transplantation, Immunosuppression, Chronic Kidney Diseases, Cardiac Allograft Vasculopathy
- Trial name
- TEAMMATE (NCT03386539)
- Testing
- Everolimus, Tacrolimus, Mycophenolate Mofetil
- Where
- 25 sites in United States
- Volunteers
- 211 people
- Sponsor
- Boston Children's Hospital
Sinus Bradycardia, Atrioventricular Block
Analysis of Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart
Heart transplants save the lives of nearly 500 children in heart failure per year. Columbia is one of the largest pediatric heart transplant centers in the world, averaging 25 transplants per year, and providing ongoing care to…
- Trial name
- NCT02462941
- Testing
- Adenosine, Cardiac catheterization
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Columbia University