Clinical trials: Pediatric Migraine
Migraine
Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE
To evaluate the efficacy and safety of zolmitriptan nasal spray (ZNS) in the acute treatment of migraine headache in subjects ages 6 to 11 years. Part 1: Approximately 20 weeks (includes screening and double-blind treatment).
- Trial name
- NCT03275922
- Testing
- ZNS
- Where
- 47 sites in United States
- Volunteers
- 374 people
- Sponsor
- Impax Laboratories, LLC
Acute Treatment of Migraine
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of migraine in children and adolescents (≥ 6 to < 18 years of age).
- Trial name
- NCT04743141
- Testing
- Rimegepant (PF-07899801)
- Where
- 124 sites in United States, Poland and 1 more
- Volunteers
- 600 people
- Sponsor
- Pfizer
Headache Disorders, Primary
Pediatric Headche Assessment Using HIT 6
The study is a prospective cohort study. The study population will include 100 children aged 6-18 years suffering from headaches who visited the Pediatric Neurology Clinic at Bnai Zion Medical Center and completed both the…
- Trial name
- NCT06598813
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Migraine
A Trial to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents
The primary objective of the study is to evaluate the long-term safety and tolerability of subcutaneous fremanezumab in the preventive treatment of migraine in pediatric participants 6 to 17 years of age (inclusive at enrollment…
- Trial name
- NCT04530110
- Testing
- Fremanezumab
- Where
- 70 sites in United States, Canada and 7 more
- Volunteers
- 499 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D LLC
Basilar Migraine
Dose Comparison Study of Topiramate in Pediatric Subjects With Basilar/Hemiplegic Migraine
The objective of this study is to assess the effectiveness and safety of topiramate in the prevention of basilar and hemiplegic migraine in children and adolescents.
- Trial name
- NCT00131443
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Monarch Medical Research
Migraine
Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine
This study will evaluate the efficacy and safety of erenumab in migraine prevention in children (6 to <12 years) and adolescents (12 to <18 years) with chronic migraine.
- Trial name
- OASIS(CM) (NCT03832998)
- Testing
- Erenumab Dose 1, Erenumab Dose 2, Erenumab Dose 3
- Where
- 101 sites in United States, Belgium and 11 more
- Volunteers
- 284 people
- Sponsor
- Amgen
Acute Migraine With or Without Aura in Adolescents
A Study to Evaluate the Safety and Tolerability of Rizatriptan for Long Term Treatment of Acute Migraine in Children and Adolescents (MK-0462-086 AM3)
To provide long term safety data for rizatriptan in children and adolescents. The primary hypothesis of the study is that rizatriptan is well tolerated in the long term treatment of acute migraine in pediatric patients age 12-17…
- Trial name
- NCT01004263
- Testing
- rizatriptan benzoate
- Volunteers
- 674 people
- Sponsor
- Organon and Co
Migraine, Headache Disorders
MIGRAFIT: Evaluating a Group Therapy Program Combining Physical Activity, Progressive Muscle Relaxation and Psychoeducation for Adolescents With Migraine
Background: Migraine is a headache disorder highly prevalent in children and adolescents. It significantly affects academic performance and quality of life.
- Conditions
- Migraine, Headache Disorders, Pediatric Migraine
- Trial name
- NCT07419607
- Testing
- Weekly group training
- Where
- Austria
- Volunteers
- 6 people
- Sponsor
- Medical University Innsbruck
Migraine, Migraine Disorders
The Childhood and Adolescent Migraine Prevention Study
The purpose of this research study is to test two medicines for migraine prevention in children and adolescents.
- Conditions
- Migraine, Migraine Disorders, Headache
- Trial name
- CHAMP (NCT01581281)
- Testing
- Amitriptyline, Topiramate
- Where
- 35 sites in United States
- Volunteers
- 488 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Headache, Headache Disorders
Responding With Evidence and Access for Childhood Headaches
This comparative effectiveness study will clarify current first-line preventive treatment approaches for use by neurologists, psychologists, and primary care providers in the context of real world care, and will demonstrate the…
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT05889624
- Testing
- CBT, Amitriptyline
- Where
- 15 sites in United States
- Volunteers
- 400 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pediatric Migraine, Headache Disorders
Propranolol for Pediatric Migraine: A Prospective Clinical Study
This prospective, controlled clinical trial was conducted to evaluate the effectiveness of propranolol compared with structured behavioral therapy in pediatric patients diagnosed with primary migraine according to ICHD-3…
- Trial name
- NCT07180043
- Testing
- Structured Behavioral Therapy, Propranolol
- Where
- Turkey (Türkiye)
- Volunteers
- 178 people
- Sponsor
- Kayseri University
Migraine in Children, Posttraumatic Headache
A Pilot Study of Intranasal Lidocaine in Acute Management of Pediatric Migraine
Headaches in children are very common and are a source of significant distress for the patient and their family. Migraines are the most common headache disorder in children and are associated with episodic pain and other symptoms…
- Trial name
- NCT03806595
- Testing
- Lidocaine 2% Injectable Solution, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Migraine
Pharmacokinetics & Safety of Cambia® in Migraine With or Without Aura in 12-17 Year Olds
Study Objectives: 1. The primary objective is to characterize the pharmacokinetics of a single oral administration of 50 mg Cambia in pediatric subjects, ages 12-17 years with a diagnosis of episodic migraine with or without…
- Trial name
- NCT02287376
- Testing
- Diclofenac Potassium for Oral Solution
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Depomed
Headache, Headache Disorders
Mind Body Balance for Pediatric Migraine
This study uses a factorial research design to evaluate a nurse delivered mind body intervention using different doses of 3 treatment components to determine the optimized treatment for headache day reduction.
- Conditions
- Headache, Headache Disorders, Headache, Migraine, Migraine
- Trial name
- NCT04715685
- Testing
- 40 minute session, 20 minute session, home practice e-health
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Migraine
AMG 334 20160172 Pediatric Migraine PK Study.
AMG 334 20160172 Pediatric Migraine PK Study.
- Trial name
- NCT03499119
- Testing
- AMG 334 Dose 1, AMG 334 Dose 2, AMG 334 Dose 3
- Where
- 14 sites in United States
- Volunteers
- 53 people
- Sponsor
- Amgen
Migraine Headache
Low-dose Propofol for Pediatric Migraine
Propofol, a general anesthetic, has been suggested to be effective for the treatment of migraine headaches in adults when used in subanesthetic doses (lower doses than those used for anesthesia or sedation).
- Trial name
- NCT01604785
- Testing
- Propofol, Standard Treatment
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Oregon Health and Science University
Migraine in Children, Pain, Neuropathic
Transnasal Sphenopalatine Ganglia Block for Management of Chronic Migraines in Pediatric Patients
Single-center, open-label, pre-post treatment pilot study to evaluate the safety and effectiveness of sphenopalatine ganglia blocks for the treatment of chronic migraine in the pediatric population.
- Trial name
- NCT04466826
- Testing
- Headache Journal, Sphenopalatine Block, Tx360
- Where
- United States
- Sponsor
- Washington University School of Medicine
Migraine in Children, Sphenopalatine Neuralgia
SPG Block for Acute Pediatric Migraine
This is a randomized double blind trial comparing an intranasal sphenopalatine block with 2% lidocaine to intravenous (0.15 mg/kg, max 10mg) prochlorperazine in patients greater than 10 years of age presenting to a pediatric…
- Conditions
- Migraine in Children, Sphenopalatine Neuralgia, Migraine in Adolescence
- Trial name
- NCT03984045
- Testing
- Lidocaine topical, Prochlorperazine Injection
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Newark Beth Israel Medical Center
Drug Resistant Epilepsy, Autism Spectrum Disorder
Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients
The goal of this observational study is to learn about the clinical and nutritional effectiveness of ketogenic diet (KD) in pediatric patients with genetic, neurological or metabolic conditions requiring KD.
- Conditions
- Drug Resistant Epilepsy, Autism Spectrum Disorder, Chronic Migraine, Brain Tumor, Pediatric
- Trial name
- NCT06309251
- Testing
- ketogenic diet (as per clinical practice)
- Where
- 3 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Danone Nutricia SpA Società Benefit
Irritable Bowel Syndrome (IBS), Functional Abdominal Pain
Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents
This protocol matches child subjects with peer mentors of similar age who have learned to function successfully with a chronic pain disorder.
- Conditions
- Irritable Bowel Syndrome (IBS), Functional Abdominal Pain, Fibromyalgia, Complex Regional Pain Syndrome (CRPS)
- Trial name
- NCT01118988
- Testing
- Mentorship
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of California, Los Angeles