Clinical trials: Pediatric Overweight, open to volunteers
Host and Microbiome, Pregnancy Outcomes
Human Genes and Microbiota in Early Life
The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life…
- Conditions
- Host and Microbiome, Pregnancy Outcomes, Pregnancy Complications, Neurodevelopmental Disorders
- Trial name
- HuGME (NCT06926166)
- Testing
- No intervention
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Type 1 Diabetes, T1D
DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions
This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a family-centered digital health intervention designed to support adolescents and young adults with…
- Conditions
- Type 1 Diabetes, T1D, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus
- Trial name
- DASH-Obesity (NCT07638345)
- Testing
- Adhera Caring Digital Program-Obesity (ACDP-O)
- Where
- Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Adhera Health, Inc.
Obesity, Adolescent, Weight Change, Body
Multi-Modal Digital Interventions for Adolescent Weight Management
The goal of this randomized controlled trial is to evaluate the effectiveness of a multi-modal digital intervention, based on the Theory of Planned Behavior (TPB), in promoting healthy weight control behaviors among overweight…
- Conditions
- Obesity, Adolescent, Weight Change, Body, Weight Stigma
- Trial name
- M2DI-AWM (NCT06920862)
- Testing
- Multi-Modal Digital Intervention
- Where
- 2 sites in Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Childhood Obesity
The Dose Trial: Dose Intensity of Behavioral Interventions for Childhood Obesity
The research team is recruiting 900 children between the ages 5-17 with obesity from Tennessee and Louisiana. The team is assigning children and their caregivers by chance to one of five groups.
- Trial name
- NCT06654323
- Testing
- Intensive Behavioral Lifestyle Modification
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- Vanderbilt University Medical Center
Overweight, Childhood, Obesity in Children
The Bloom Study - a Safe and Healthy Start in Life
The aim of the Bloom Study is to promote healthy weight development among infants through a home-based health promoting intervention implemented in the Danish setting of community health nurses.
- Trial name
- NCT06705400
- Testing
- Multi-behavioural
- Where
- Denmark
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Gliosis, Child Obesity
Building Research for Intervention Development in Gliosis and Eating Habits
The goal of this study is to 1) use magnetic resonance imaging (MRI) to evaluate the effect of nutritious foods on inflammation in the human hypothalamus of children and 2) assess the feasibility and acceptability of nutritious…
- Conditions
- Gliosis, Child Obesity, Eating
- Trial name
- BRIDGE (NCT06870578)
- Testing
- Diet modification
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Washington
Obesity-associated Asthma
Metformin Treatment for Children With Obesity-associated Asthma
The goal of this clinical trial is to learn if metformin can improve asthma control in overweight and obese children with mild, moderate, or severe asthma.
- Trial name
- MOACT (NCT07622290)
- Testing
- Metfomin
- Where
- Qatar
- Volunteers
- 182 people
- Sponsor
- Prof Ibrahim Janahi
Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity
Non-Invasive Diagnostic Panel for MASLD in Children With Obesity
This prospective, single-center, two-group observational study evaluates a non-invasive multi-parameter diagnostic panel for metabolic dysfunction-associated steatotic liver disease (MASLD) in children with obesity.
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Pediatric Obesity, Insulin Resistance Syndrome
- Trial name
- PedMASLD-Pilot (NCT07731360)
- Testing
- Non-Invasive Multi-Parameter Diagnostic Panel
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Kayseri City Hospital
Prevention of Childhood Obesity, Community Health Education
EFFECT OF A ONLINE NUTRITION EDUCATION PROGRAM IN PRESCHOOLER'S FAMILIES ON THEIR ADHERENCE TO THE MEDITERRANEAN DIET
Questions: What's the effect of an online nutritional educational program in preschoolers families on the adherence to the mediterranean diet? What's the effect of this program on the BMI at 3 years follow-up? Study Description A…
- Trial name
- ELIKUME (NCT06828367)
- Testing
- Online family educational intervention and cooking workshop
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fundacion Miguel Servet
Pediatric Obesity, Training Effectiveness
Effects of HIIT and Concurrent HITT/Plyometric Training on Muscle-tendon Structure, Function and Metabolism in Pediatric Population With Obesity at Different Biological Maturation States (HIIT-PRO Kids).
The randomized controlled trial will compare the effects of a High-intensity interval training (HIIT) protocol versus a HIIT plus plyometric training in the muscle-tendon structure function and metabolism of the pediatric…
- Trial name
- HIIT-PRO-kids (NCT06727500)
- Testing
- HIIT plus plyometric training, HIIT
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad Nacional Andres Bello
Child Obesity
More Outside Your Door: a Diet/physical Activity Intervention to Decrease Risk of Obesity in Alaska Native Preschoolers
The preschool age is a crucial period of growth and an optimal time to begin to establish healthy eating and physical activity habits leading to better food and activity choices into adulthood, thereby minimizing risk for…
- Trial name
- MOYD (NCT06303544)
- Testing
- Wedge 1
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Alaska Native Tribal Health Consortium
Pediatric Fractures, Hypovitaminosis D
Bone Outcomes, Obesity, Sunlight, and Trauma in Children
Prospective case-control study of children (3-15 years) after low-energy trauma. We compare serum bone metabolic markers (25OHD, PTH, ALP, calcium, phosphate), BMI/percentile, and dietary calcium intake between fracture and…
- Conditions
- Pediatric Fractures, Hypovitaminosis D, Obesity and Overweight
- Trial name
- BOOST (NCT07143552)
- Where
- 2 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Adolescence Obesity
Phase Ib Study of Efsubaglutide Alfa Injection in Obese Adolescents
This is a Phase Ib, randomized, double-blind, placebo-controlled clinical study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Efsubaglutide Alfa Injection following multiple-dose…
- Trial name
- NCT07693426
- Testing
- Efsubaglutide Alfa 5 mg QW, Efsubaglutide Alfa 10 mg QW, Efsubaglutide Alfa 20 mg QW
- Where
- 5 sites in China
- Volunteers
- 36 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
Obesity, Childhood
Monthly Boluses Versus Daily Doses for Correcting Blood Vitamin D Deficit in Obese Children and Adolescents
Childhood obesity is one of the most serious public health challenges of the 21st century, with an increasing prevalence over time in developed countries.
- Trial name
- OBEVIDOS (NCT03516968)
- Testing
- Monthly bolus of cholecalciferol per os, Daily dose of cholecalciferol per os
- Where
- 4 sites in France
- Volunteers
- 68 people
- Sponsor
- Hospices Civils de Lyon
Childhood Overweight and Obesity Immersive Physical Activity
Immersive Physical Activity Program for Overweight Schoolchildren
Childhood overweight and obesity are major public health concerns associated with increased cardiometabolic risk and reduced quality of life.
- Trial name
- PEESO (NCT07681856)
- Testing
- RVI_Experimental_Immersive Virtual Reality Exergame Program, RVI_ControGroup_Immersive Virtual Reality Exergame Program
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Vigo
Pediatric Obesity
Developmental Trajectories of Reinforcer Pathology and Childhood Obesity
The goal of this observational study is to understand how children's food preferences, physical activity, and decision-making change over time and how these behaviors relate to body weight and overall health.
- Trial name
- TRACK (NCT07229508)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Childhood Obesity
Phentermine's Impact on Treatment in Teens
PhITT is a Phase IIb, multicenter, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of phentermine (16 mg daily) in adolescents aged 12 to <18 years with obesity.
- Trial name
- PhITT (NCT07282340)
- Testing
- Phentermine
- Where
- 8 sites in United States
- Volunteers
- 240 people
- Sponsor
- Russell McCulloh, MD
Binge Eating Disorder, Binge Eating
Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents
The main purpose is to investigate the effectiveness of a 10-week multicomponent camp intervention to reduce BE behavior in children and adolescents and explore in a randomized controlled setting if a parent-based…
- Conditions
- Binge Eating Disorder, Binge Eating, Loss of Control Eating, Overweight , Obesity
- Trial name
- STOB (NCT07301541)
- Testing
- A 10-week multicomponent camp intervention for children, A BED intervention for parents
- Where
- 2 sites in Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Overweight, Childhood, Obesity, Childhood
Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline
The goal of this study is to evaluate the effectiveness of CHAMPION ("Comparative-effectiveness of a Healthy lifestyle and Asthma Management Program, In-person vs ONline"), a primary care-based intervention to address childhood…
- Conditions
- Overweight, Childhood, Obesity, Childhood, Asthma in Children
- Trial name
- CHAMPION (NCT06432790)
- Testing
- CHAMPION
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Obesity, Childhood
Effects of Auricular Acupressure Versus Intermittent Dietary Restriction in Children With Gastric Heat and Dampness Obstruction
This is a three-month randomized controlled trial to investigate the effects of auricular acupressure versus Intermittent carbohydrate restriction on cardiometabolic risk in obese children with gastric heat and dampness…
- Trial name
- NCT05847478
- Testing
- Auricular acupressure of traditional Chinese Medicine, Intermittent low carbohydrate diet, Health education
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Children's Hospital of Fudan University