Clinical trials: Pediatric Population
Fabry Disease
A Study of Two Fabrazyme (Agalsidase Beta) Dosing Regimens in Treatment-naïve, Male Pediatric Patients Without Severe Symptoms
The purpose of this study was to determine whether 2 alternative dosing regimens of Fabrazyme (Agalsidase beta) (1.0 mg/kg every 4 weeks or 0.5 mg/kg every 2 weeks) were effective in treatment-naïve pediatric participants without…
- Trial name
- FIELD (NCT00701415)
- Testing
- Agalsidase beta
- Where
- 12 sites in United States, Argentina and 7 more
- Volunteers
- 31 people
- Sponsor
- Genzyme, a Sanofi Company
Epilepsy, Mental Retardation
Use of Sustained Release Antiepileptic Medication (Depakote® ER) for Pediatric Epilepsy in a Mental Retardation/Developmental Disorder Population
This study is being done to see if children with learning problems can learn how to swallow pills without chewing them. The reason this is important is that if a person has seizures, medications must be taken every day.
- Conditions
- Epilepsy, Mental Retardation, Developmental Disabilities
- Trial name
- NCT00207935
- Testing
- Swallow instruction
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's National Research Institute
Pain, Postoperative, Developmental Dislocation of Hip
Efficacy and Safety of Quadratus Lumborum Block Versus Pericapsular Nerve Group Block in Pediatric Hip Surgery
Surgical procedure including hip joint surgery is extremely painful and associated with considerable postoperative pain in children despite the use of systemic opioids.
- Trial name
- TQL (NCT05349656)
- Testing
- TQL block, PENG block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Pain, Procedural
Oral Morphine Versus Ketamine in Pain Management
The study will mainly focus on procedural pain management using oral morphine versus rectal ketamine during paediatric burn and wound dressing at Mbarara Regional Referral Hospital.
- Trial name
- NCT05163366
- Testing
- GROUP A, GROUP B
- Where
- 2 sites in Uganda
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Caregiver Burden
Eye Movement Desensitization and Reprocessing Group Treatment for Caregivers of Pediatric Brain Tumor Patients
Caregivers of pediatric brain tumor survivors may develop high levels of psychological distress, mostly depression and anxiety, with effects comparable to those of a traumatic event.
- Trial name
- NCT06339814
- Testing
- Eye Movement Desensitization and Reprocessing Integrative Group Treatment Protocol, Treatment As Usual
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- IRCCS Eugenio Medea
Healthy, Obese
Reference Values of Aerobic Fitness in the Contemporary Paediatric Population
In most pediatric medical conditions, tremendous progress in pediatrics has significantly improved the overall prognosis and transferred the mortality from childhood to adulthood.
- Trial name
- SAIN&NORMES (NCT04876209)
- Where
- France
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Bipolar Depression
Pediatric Bipolar Depression
The purpose of this study is to determine if quetiapine fumarate extended-release (quetiapine XR or SEROQUEL® XR) 150 to 300 mg/day taken by itself is effective and safe in treating children or adolescents aged 10 to 17 with…
- Trial name
- NCT00811473
- Testing
- Quetiapine XR
- Where
- 48 sites in United States, Colombia and 5 more
- Volunteers
- 193 people
- Sponsor
- AstraZeneca
Encephalitis
Safety and Immunogenicity of the Japanese Encephalitis Vaccine IC51 (IXIARO®) in a Pediatric Population
The primary objective is to assess the systemic and local safety profile of purified inactivated Japanese Encephalitis Virus (JEV) vaccine IC51 administered in two doses in a 28 days interval up to Month 7 after the first IC51…
- Trial name
- NCT01041573
- Testing
- IC51 Japanese Encephalitis, Havrix®720, Prevnar
- Where
- 2 sites in Philippines
- Volunteers
- 1,869 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
Narcolepsy
Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy
Primary Objectives: The primary objectives of the study are to determine the effectiveness of PROVIGIL treatment, compared to placebo treatment, in children and adolescents with excessive sleepiness (ES) associated with…
- Trial name
- NCT00107796
- Testing
- Modafinil
- Where
- 73 sites in United States, Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cephalon
Overactive Bladder (OAB), Pharmacokinetics of Mirabegron
A Study to Evaluate Mirabegron in Pediatric Participants From 5 to Less Than 18 Years of Age With Overactive Bladder (OAB)
The purpose of this study was to evaluate the efficacy of mirabegron in children (5 to < 12 years of age) with OAB. This study will also evaluated the safety and tolerability of mirabegron in pediatric participants with OAB and…
- Trial name
- Dolphin (NCT04641975)
- Testing
- Mirabegron
- Where
- 15 sites in Belgium, France and 8 more
- Volunteers
- 26 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Fractures in Children
Dating of Child Fractures : Chronological Repers From the Radiological Evolution of a Series of Femur Fractures
Although several studies have studied the predictive nature of non-accidental trauma of the different types of fractures and in particular on the femur, the physiological and radiological particularities of the child make it…
- Trial name
- DFE (NCT05625152)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Dental Caries
Knowledge, Attitude, And Practice In A Group Of Egyptian Dentists Towards Preventive Measures In Pediatric Dentistry: A Cross-Sectional Study
The study will include general dental practitioners or dental specialists from Police Academy Hospital and pediatric dentists from Pediatric dentistry department at Faculty of Dentistry Cairo University.
- Trial name
- NCT03556865
- Testing
- A self administered questionnaire
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hemianopia, Brain Tumor
Visual Rehabilitation in Children With Homonymous Hemianopia: a Pilot Study on Virtual-reality Stimulation
There are currently no visual rehabilitation strategies for children presenting visual field defects consecutive to a brain tumor or its treatment.
- Conditions
- Hemianopia, Brain Tumor, Children, Only
- Trial name
- HH-IVR (NCT05065268)
- Testing
- Immersive Virtual-Reality Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- The Hospital for Sick Children
Pediatric Cancer
A Hypnosis-based Group Intervention to Improve Quality of Life in Children With Cancer and Their Parents.
Background: A lot of children with cancer suffer from emotional distress, fatigue and relational difficulties. Their parents are also impacted by the disease: their responsibilities increase and they can feel more distressed and…
- Trial name
- NCT03435042
- Testing
- Self care + Hypnosis group
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Liege
Ocular Redness, Eye Irritation
An Investigation of FID 123320 for the Reduction of Ocular Redness in Pediatric and Adult Populations
The purpose of this study is to assess the safety and efficacy of FID 123320 Ophthalmic Solution compared to Vehicle for relieving redness of the eye due to minor eye irritations in pediatric and adult populations.
- Trial name
- NCT06538662
- Testing
- FID 123320 Ophthalmic Solution, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 283 people
- Sponsor
- Alcon Research
Gastroesophageal Reflux Disease (GERD), Erosive Esophagitis
Esomeprazole for Treatment of GERD in Pediatric Patients
To look at the safety and improvement in symptoms of a once a day dosing of esomeprazole in children 1 to 11 years old with inflammation of their esophagus or food pipe ("esophagitis") caused by gastroesophageal reflux disease…
- Conditions
- Gastroesophageal Reflux Disease (GERD), Erosive Esophagitis, Non-erosive Esophagitis
- Trial name
- NCT00228527
- Testing
- Esomeprazole (Nexium)
- Where
- 36 sites in United States, Belgium and 2 more
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Nursing Caries, Palliative Care
Trend Analysis of the Service of Pediatric Palliative Care
Palliative care has received considerable attention in Taiwan in recent years. The relevant research has been widely conducted for palliative care in adult population.
- Conditions
- Nursing Caries, Palliative Care, Pediatric Population, Pediatric Cancer
- Trial name
- NCT03925831
- Where
- Taiwan
- Volunteers
- 5,000 people
- Sponsor
- National Taiwan University Hospital
Colonoscopy
A Safety and Efficacy Evaluation of 3 Bowel Preparations in the Pediatric Population
This randomized, parallel, multi-center, single-blind study is designed to compare the safety and efficacy of 3 bowel preparations in pediatric subjects scheduled to undergo a colonoscopy for a routinely accepted indication.
- Trial name
- NCT00425594
- Testing
- HalfLytely and Bisacodyl Tablets - Formulation 1, HalfLytely and Bisacodyl Tablets - Formulation 2, NuLYTELY
- Where
- 26 sites in United States
- Volunteers
- 150 people
- Sponsor
- Braintree Laboratories
Wounds and Injuries
Evaluation of Emergency Suturing With Absorbable Versus Non-absorbable Suture Material in a Pediatric Population
The investigators recruit patients admitted to the Pediatric Emergency Department of the Geneva's University Hospital with open wounds needing suture.
- Trial name
- NCT02777346
- Testing
- Absorbable, Non absorbable
- Where
- Switzerland
- Volunteers
- 550 people
- Sponsor
- Pediatric Clinical Research Platform
Childhood Obesity
Community-based Program to Treat Childhood Obesity
This study will evaluate the effectiveness of a comprehensive community based program on reducing excess weight in children and teens. This study will recruit 150 participants between the ages of 6-12 and 13-17.
- Trial name
- NCT01374646
- Testing
- JOIN Intervention
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- UnitedHealth Group