Clinical trials: Pediatric Population
Pulmonary Function Testing
Validation of the STS Device for Pulmonary Function Test in Pediatric Population
This prospective, single-arm, self-controlled validation study aims to evaluate the accuracy and safety of the Spirometry Test System (STS) handheld device in measuring pulmonary parameters in pediatric subjects aged 7-17 years.
- Trial name
- NCT07430709
- Testing
- Spirometry Test System (STS)
- Volunteers
- 160 people
- Sponsor
- Technopulm
Asthma Bronchiale
Evaluation of Alterations in the Gut Microbiota in Pediatric Bronchial Asthma
Asthma constitutes a major chronic noncommunicable disease, globally it affects about 300 million people and the incidence has been steadily increasing in recent decades; it affects about 10% of children and is the leading…
- Trial name
- MicroAsm (NCT06842836)
- Testing
- Study intervention
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Obesity
Competency Based Approaches for Community Health 2
One-size-fits-all approaches have failed to demonstrate sustained effects on childhood obesity, especially among low-income minority families, who experience constantly changing barriers to engaging in health behavior.
- Trial name
- COACH (NCT04971044)
- Testing
- COACH, School Readiness Intervention
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Migraine, Headache Disorders
High-Intensity Interval Training and Progressive Muscle Relaxation as a Movement-Based Group Intervention for the Non-Pharmacological Prevention of Adolescent Migraine
Background: The prevalence of migraine during adolescence is 7.7%, affecting 9.7% of girls and 6.0% of boys. Despite its high prevalence, treatment options remain limited.
- Conditions
- Migraine, Headache Disorders, Pediatric Migraine
- Trial name
- MigraFit (NCT07850622)
- Testing
- Weekly group training
- Where
- Austria
- Volunteers
- 27 people
- Sponsor
- Medical University Innsbruck
Gastrointestinal Cancer, Colorectal Cancer
GastroIntestinal Cancer in Children and Adolescents
The goal of this observational population-based cohort study is to investigate the clinical characteristics and outcomes of children and adolescents with primary gastrointestinal malignancies registered in the publicly available…
- Conditions
- Gastrointestinal Cancer, Colorectal Cancer, Gastric Cancer, Hepatoblastoma
- Trial name
- GICCA (NCT05693519)
- Where
- 2 sites in Netherlands
- Volunteers
- 2,500 people
- Sponsor
- Paul G. Kemps, MD
Bariatric Surgery Candidate, Obesity, Morbid
Adolescents Bariatric Surgery Cohort Survey
Obesity affects 3%-4% of the pediatric population and leads to cardiac mortality during adult life. Bariatric surgery is the best treatment for weight loss and preventing obesity associated comorbidities in adults, but its…
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Obesity, Adolescent
- Trial name
- BariAdo (NCT04766801)
- Testing
- Laparoscopic adjustable gastric banding
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Obstructive Sleep Apnea of Child
Cytokine Persistence as a Marker of Inflammation in the at Risk, Low Socioeconomic Status Pediatric Population
The investigators wish to study the role of persistent markers of inflammation in executive function in young children during critical periods of synaptogenesis (ages 2-3).
- Trial name
- NCT03134300
- Testing
- Cytokine from blood
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
type1diabetes, Pediatrics
AI for Glycemic Events Detection Via ECG in a Pediatric Population
Paediatric Type 1 Diabetes (T1D) patients are at greater risk for developing severe hypo and hyperglycaemic events due to poor glycaemic control and incorrect Insulin administration.
- Trial name
- NCT05278143
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Malaria, Vivax
An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older
The aim of this study is to collect efficacy and safety data to support the registration of tafenoquine in India.
- Trial name
- NCT06666491
- Testing
- Tafenoquine, Primaquine, Chloroquine
- Where
- 5 sites in India
- Volunteers
- 324 people
- Sponsor
- GlaxoSmithKline
Tinea Corporis
Pediatric Subjects With Tinea Corporis
The study is being done to see how well the study cream works when applied once a day to affected area of child (where they have ringworm).
- Trial name
- NCT02227290
- Testing
- Naftin Cream
- Where
- 19 sites in United States, Dominican Republic and 3 more
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Electrocardiography Education
ECG TRAİNİNG METHODS FOR PEDİATRİC RESİDENTS
This randomized controlled study evaluated the effectiveness of two electrocardiography (ECG) training methods among pediatric residents.
- Trial name
- NCT07837635
- Testing
- Conference-Based ECG Training, Small-Group Case-Based ECG Training
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Tick-borne Encephalitis
Prevalence of Tick-borne Encephalitis in the Pediatric Population Treated at the HUS and Characterization of Confirmed Pediatric Cases
Tick-borne encephalitis (TBE) is a zoonosis mainly transmitted to humans by the bite of ticks of the genus Ixodes and, to a lesser extent, by the consumption of contaminated and unpasteurized dairy products.
- Trial name
- TBE-KID (NCT05607394)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Diabetes Mellitus, Type 2
Finding a Safe and Effective Dose of Linagliptin in Pediatric Patients With Type 2 Diabetes
The main objective of this study is to identify the dose of linagliptin in paediatric patients. Other efficacy objectives include the comparison of the lowering effect of linagliptin low dose, high dose and placebo on the fasting…
- Trial name
- NCT01342484
- Testing
- BI1356 low dose, BI1356 high dose
- Where
- 25 sites in United States, Canada and 7 more
- Volunteers
- 40 people
- Sponsor
- Boehringer Ingelheim
Stress
Evaluation Of Stress Levels Of Pediatric Dentist Performing Dental Treatment In The Operating Room
This study will measure the stress levels of pediatric dentists performing dental treatments under deep sedation and general anesthesia.
- Trial name
- NCT07541508
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hematologic Malignancies, Nonmalignant Diseases
Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation
Fludarabine is a chemotherapy drug used extensively in bone marrow transplantation. The goal of this study is to determine what causes some children to have different drug concentrations of fludarabine in their bodies and if drug…
- Conditions
- Hematologic Malignancies, Nonmalignant Diseases, Immunodeficiencies, Hemoglobinopathies
- Trial name
- HCT (NCT01316549)
- Testing
- Fludarabine
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Francisco
Generalized Anxiety Disorder, Separation Anxiety Disorder
Transdisciplinary Studies of CBT for Anxiety in Youth: Child Anxiety Treatment Study
The purpose of this study is to investigate neurobehavioral, affective, and social processes that may influence and predict treatment response in pediatric anxiety disorders.
- Conditions
- Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
- Trial name
- CATS (NCT00774150)
- Testing
- Cognitive Behavioral Therapy, Client Centered Therapy
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Eosinophilic Esophagitis
Prospective Database for Eosinophilic Esophagitis (EoE) of Pediatric Population
Eosinophilic Esophagitis (EoE) is a chronic, immune-mediated allergic inflammatory disorder that is being diagnosed with increased frequency.
- Trial name
- EoE (NCT05176249)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Post Operative Pain After Pediatric Hip Surgery
Comparison of Ultrasound Guided Caudal Block and Ultrasound Guided Pericapsular Nerve Group Block for Pediatric Hip Surgery
Surgical repair of the hip can be extremely painful and is associated with considerable postoperative pain in children despite the use of systemic opioids.
- Trial name
- NCT04336085
- Testing
- caudal block, pericapsular nerve group block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Plasmodium Falciparum Infection
Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria
Primary objective: To assess the Day 28 efficacy defined as the percentage of patients with no parasitic recrudescence, of 3 treatment groups - 3 dose levels of ferroquine associated with artesunate - for a 3-day treatment.
- Trial name
- FARM (NCT00988507)
- Testing
- Ferroquine (SSR97193), artesunate
- Where
- 10 sites in Benin, Burkina Faso and 4 more
- Volunteers
- 440 people
- Sponsor
- Sanofi
Stage II Childhood Hodgkin Lymphoma, Stage III Childhood Hodgkin Lymphoma
Adcetris (Brentuximab Vedotin), Combination Chemotherapy, and Radiation Therapy in Treating Younger Patients With Stage IIB, IIIB and IV Hodgkin Lymphoma
This pilot phase II trial studies how well giving brentuximab vedotin, combination chemotherapy, and radiation therapy works in treating younger patients with stage IIB, IIIB or IV Hodgkin lymphoma.
- Conditions
- Stage II Childhood Hodgkin Lymphoma, Stage III Childhood Hodgkin Lymphoma, Stage IV Childhood Hodgkin Lymphoma
- Trial name
- NCT01920932
- Testing
- brentuximab vedotin, etoposide, prednisone
- Where
- 6 sites in United States
- Volunteers
- 77 people
- Sponsor
- St. Jude Children's Research Hospital