Clinical trials: Pediatric Trauma
Pediatric Extremity Fracture, Pediatric Extremity Soft Tissue Injury
Peripheral Nerve Blocks in Pediatric Orthopedic Patients
Context: Single shot peripheral nerve blocks have limited duration of action depending on the local anesthetic agent used in the block. But it rarely lasts longer than 12 hrs.
- Trial name
- NCT02236130
- Testing
- Regional block, General Anesthesia, Local Anesthetic Ropivacaine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Elbow Fracture
The Post-Operative Pain Management of Pediatric Supracondylar Elbow Fractures
The goal of this study is to compare different ways of treating pain after surgery. This research study involves subjects who have a supracondylar elbow fracture and need surgery.
- Trial name
- NCT01328782
- Testing
- Oxycodone with Acetaminophen, Bupivacaine 0.25%, Ropivacaine 0.20%
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Colorado, Denver
Acute Respiratory Distress Syndrome, Acute Lung Injury
Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury
Lung units which participate in gas exchange are known as 'recruited' lung. Patients with lung injury suffer from a proportion of units which do not participate in gas exchange (i.e.
- Trial name
- Recruitment (NCT00830284)
- Testing
- Recruitment maneuver
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Boston Children's Hospital
Congenital Heart Defects
Is Levosimendan Superior to Milrinone Regarding Acute Kidney Injury After Cardiac Surgery for Congenital Heart Disease?
The aim of the study is to assess the ability of Levosimendan to reduce the postoperative acute kidney injury in pediatric patients undergoing surgery for congenital heart disease (CHDs).
- Trial name
- MiLe-1 (NCT02232399)
- Testing
- Levosimendan, Milrinone
- Where
- 2 sites in Finland, Sweden
- Volunteers
- 72 people
- Sponsor
- Göteborg University
Burns
Comparison of Mepitel Ag vs Antibiotic Ointment Used With Soft Cast Technique for Treatment of Pediatric Burns
The aim of this study is to compare Mepitel Ag to Triple antibiotic ointment impregnated Adaptic gauze when used with the soft cast technique to assess overall time to healing, yeast infection rate and parents perception of pain…
- Trial name
- NCT02681757
- Testing
- triple antibiotic ointment dressing, Mepitel Ag
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Ankle Sprain
FS-67 in the Treatment of Pediatric Patients With Ankle Sprain
The objective of this study is assess the efficacy and safety of single and multiple applications of the FS-67 patch in the treatment of ankle sprain in pediatric population (ages 13-17).
- Trial name
- NCT01037816
- Testing
- FS-67 Patch
- Where
- 23 sites in United States
- Volunteers
- 252 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Pediatric Obesity
Healthy Eating for My Infant (HEMI)
Infants from underserved and minority backgrounds are at increased risk for obesity and poor feeding and nutrition outcomes, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT04977947
- Testing
- Healthy Eating for My Infant
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Blood Loss, Surgical
Safety and Immunogenicity Study of Recombinant Thrombin (rThrombin) in Pediatric Participants
The objective of this study is to assess the safety and immunogenicity of recombinant thrombin (rThrombin) administered as an aid to hemostasis during burn wound excision and skin grafting in pediatric patients, newborn through…
- Trial name
- NCT00859547
- Testing
- rThrombin, 1000 IU/mL
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- ZymoGenetics
Burns
The Effect of Selenium Supplementation Among Pediatric Patients With Burns
The selenium status of children with major burns is suboptimal which may increase the incidence of infection. Se requirements during critical illness are not known.
- Trial name
- NCT00860379
- Testing
- Selenium1, Selenium2
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Shriners Hospitals for Children
Soft Tissue Injuries
Study of PK and Safety of the LicartTM Topical System in Pediatric and Adult Participants With Minor Soft Tissue Injury
A multi-center, prospective, open-label, controlled study of the pharmacokinetics and safety of the LicartTM topical system in pediatric and adult participants with minor soft tissue injuries.
- Trial name
- NCT05171673
- Testing
- Licart™ (diclofenac epolamine) topical system
- Where
- 11 sites in United States
- Volunteers
- 151 people
- Sponsor
- IBSA Institut Biochimique SA
Acute Pain
A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients
The purpose of this study is to demonstrate the efficacy and safety of Intravenous (IV) acetaminophen plus rescue opioids for the relief of moderate to severe acute pain in neonates and infants (age < 2 years) compared to placebo…
- Trial name
- NCT01635101
- Testing
- IV Acetaminophen, IV Control
- Where
- 22 sites in United States
- Volunteers
- 197 people
- Sponsor
- Mallinckrodt
Surgical Site Infection
Bacterial Contamination: Iodine vs Saline Irrigation in Pediatric Spine Surgery
This study will evaluate the safety of povidone-iodine irrigation in pediatric spinal patients by collecting pre- and post-operative safety labwork.
- Trial name
- NCT02527512
- Testing
- Povidone-Iodine, Normal Saline
- Where
- 2 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Burns, Sedation
Dexmedetomidine Cardiovascular Safety in Pediatric Burn Patients
Dexmedetomidine is a sedative drug approved for adult patients, intubated, in intensive care units. We are studying whether this drug is cardiovascularly safe in pediatric patients who have recently been burned.
- Trial name
- NCT00697788
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Surgical Site Infection, Vancomycin
Pharmacokinetics of Preoperative Vancomycin
A study of plasma and tissue vancomycin pharmacokinetics in pediatric surgical patients.
- Trial name
- NCT03453684
- Testing
- Administration of Vancomycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Deformity, Defect, Congenital
Observational Study on JuniOrtho Plating System for Deformities and Fractures Treatment in Lower Limb
Orthofix Srl put the JPS on the European market (2019) by the mean of a pre-market clinical evaluation made under the Medical Device Directive (MDD) requirements that were based on the analysis of the scientific literature of…
- Conditions
- Deformity, Defect, Congenital, Trauma
- Trial name
- JPS (NCT05245617)
- Testing
- JuniOrtho™ Plating System™
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Orthofix s.r.l.
Neuromuscular Scoliosis
Wound Vac Bandage Comparison After Spinal Fusion
The purpose of this study is to evaluate the effectiveness of incisional vacuum-assisted closure (VAC) therapy in the prevention of infection after posterior spinal fusion for pediatric neuromuscular scoliosis, in comparison to a…
- Trial name
- WV (NCT03000010)
- Testing
- Incisional Wound Vac, Standard Bandage
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Michigan