Clinical trials: Pelvic Diseases
Prostatitis, Chronic Pain Syndrome
Botox for Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
The objective of this study is to evaluate the safety and efficacy of intraprostatic injection of Botox for the treatment of men diagnosed with chronic nonbacterial prostatitis/chronic pelvic pain syndrome (CP/CPPS).
- Trial name
- NCT00529386
- Testing
- Botox
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Queen's University
Endometriosis
Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups
The goal of this clinical trial is to learn if a wearable brain stimulation device called NettleEndo can reduce chronic pelvic pain and improve wellbeing in women with endometriosis.
- Trial name
- RELIEF (NCT06974773)
- Testing
- NettleEndo
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Samphire Group, Inc.
Endometritis, Cesarean Section; Infection
Two-drug Antibiotic Prophylaxis in Scheduled Cesarean Deliveries
Cesarean deliveries are the most common surgical procedure performed in the United States. A significant decrease in cesarean delivery associated maternal morbidity has been achieved with preoperative prophylactic single-dose…
- Conditions
- Endometritis, Cesarean Section; Infection, Wound Infection
- Trial name
- NCT03960970
- Testing
- Azithromycin 500 mg, Mefoxin 2g
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- RWJ Barnabas Health at Jersey City Medical Center
Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse (POP)
Effectiveness of Perineorrhaphy in Pelvic Organ Prolapse Surgery
This is an observational registry-based study of long-term outcome after vaginal native tissue repair for pelvic organ prolapse designed to emulate a pragmatic open-label two-arm trial for which patients, in whom perineorrhaphy…
- Trial name
- PINPOPS (NCT07006129)
- Testing
- Perineorrhaphy, No perineorrhaphy
- Where
- Sweden
- Volunteers
- 40,646 people
- Sponsor
- Lund University
Menopause, Perimenopausal Disorder
Pelvic Floor Symptoms Across Menopausel Stages
The menopausal transition is associated with substantial hormonal alterations that may adversely affect lower urinary tract function, bowel function, and sexual health.
- Trial name
- NCT07690137
- Testing
- Assessment for Lower Urinary Tract Symptoms, Assessment for Bowel Symptoms, Constipation Severity Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Bezmialem Vakif University
Cervical Cancer
Para Aortic Lymphadenectomy : Always ?
Cervical cancer affects more than 3000 new cases per year in France. The treatment of stage IB3 to IVA cervical cancer is based on concomitant radio-chemotherapy.
- Trial name
- PALA (NCT04392895)
- Testing
- Para Aortic Lymphadenectomy (PAL) by laparoscopy
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Montpellier
Chronic Prostatitis, Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Effects of Proxelan Somministration in Patients With Chronic Prostatitis
The purpose of the study is to determinate the antinflammatory effects of the Proxelan on a cohort of patients affected by prostatitis'like symptoms and clinical evidence of abacterical prostatistis, trough a significative…
- Conditions
- Chronic Prostatitis, Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Premature Ejaculation
- Trial name
- NCT03629769
- Testing
- Proxelan
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pisa
Lower Urinary Tract Symptoms
Connective Tissue Manipulation on Pelvic Floor Muscle Functions in Children
Lower urinary tract dysfunction (LUTD) is a disease group with subgroups that make up 40% of the patients were admitted to the pediatric urology clinic.
- Trial name
- NCT05824429
- Testing
- Urotherapy, Diaphragmatic Breathing Exercises, PFM Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yeditepe University
Sexual Function
Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy
This is a single center, double-blind, randomized controlled trial evaluating the change in sexual function in women undergoing vaginal repair for pelvic organ prolapse.
- Trial name
- FaVR (NCT01779739)
- Testing
- Perineorrhaphy
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Pelvic Organ Prolapse, Prolapse
A New POP (Pelvic Organ Prolapse) Scoring System: Validity and Reliability
There is a strong need for a better, simplified and informative applicable classification system that should be used to speak a common descriptive language among health care providers that treat POP.
- Conditions
- Pelvic Organ Prolapse, Prolapse, Prolapse, Vaginal, Prolapse Uterus
- Trial name
- NCT06520722
- Testing
- Prolapse scoring system
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Rectocele, Enterocele
A Study Evaluating the Clinical Outcome of a Modified d'Hoore Technique for Laparoscopic Ventral Mesh Rectopexy
The purpose of this observational study is to evaluate the clinical outcome of a modified d'Hoore technique for laparoscopic ventral mesh rectopexy in patients with primary rectal prolapse, rectocele and/or enterocele.The goal of…
- Conditions
- Rectocele, Enterocele, Rectal Prolapse
- Trial name
- POP-01 (NCT04564677)
- Testing
- Ifabond (Péters surgical)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Duomed
Radiation Disease
Pelvic Radiation Disease in Childhood Cancer Survivors
This study aims to characterise the impact of radiotherapy on physical symptoms and quality of life in childhood and young adult cancer survivors.
- Trial name
- NCT05533541
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Urinary Tract Infection, Pelvic Organ Prolapse
L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection.
This study will include women who will undergo pelvic reconstructive surgery and/or anti-incontinence sling procedures. Patients will be randomized to the combination of L-methionine, Hibiscus Sabdariffa and Boswellia Leaf…
- Conditions
- Urinary Tract Infection, Pelvic Organ Prolapse, Urinary Incontinence
- Trial name
- NCT02216253
- Testing
- L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS San Raffaele
Cerebral Palsy, Spastic Diplegia
Pelvic Alignment in Relation to Standing Balance and Selective Motor Control in Children With Spastic Diplegia
This study will be conducted to identify the relation between pelvic alignment and standing balance and also the relation between pelvic alignment and selective motor control in children with spastic diplegic cerebral palsy.
- Trial name
- NCT05014451
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hyperlordosis
Graston Technique vs Dynamic Oscillation Stretching Technique For High Heel Users And Its Impact On Body Posture
In high heel users, most of the previous work has focused on the lower limb. However, we did not find any study that specifically targeted the lumbar region.
- Trial name
- NCT07138924
- Testing
- Graston Technique, Dynamic Oscillatory Stretch Technique
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Chronic Pelvic Pain Syndrome (CPPS)
Kinesiophobia, Physical Activity, Sleep, and Quality of Life in Women With Chronic Pelvic Pain
The study will include women who present to the Obstetrics and Gynecology outpatient clinic of Kırşehir Ahi Evran Training and Research Hospital with complaints of pelvic pain and are diagnosed with PCAS after a detailed…
- Trial name
- NCT07833280
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Endometriosis, Mobility Limitation
ENDOMETRIOSIS - MRI
Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes…
- Conditions
- Endometriosis, Mobility Limitation, Magnetic Resonance Imaging, Diagnosis
- Trial name
- ENDO-MRI (NCT05779462)
- Testing
- Dynamic MRI Sequence
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Cystocele, Pelvic Organ Prolapse
Safety and Efficacy of Non-ablative Er:YAG Laser Therapy for the Treatment of Pelvic Organ Prolapse and Coexisting Stress Urinary Incontinence: A Retrospective Case Series.
The objective of the study is to retrospectively collect the data on patients who underwent pelvic organ prolapse treatment using a non-ablative Er:YAG laser with SMOOTH mode and to conduct an objective evaluation of safety and…
- Conditions
- Cystocele, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- NCT04417413
- Testing
- Fotona ProlapLase
- Where
- Serbia
- Volunteers
- 41 people
- Sponsor
- Aleksandra Novakov Mikic
Amenorrhea, Dysmenorrhea
Ethinyl Estradiol and Cyproterone Acetate in Irregular Menstruation
This is a Phase IV, randomized, double-blind, comparative study of the use of two preparations of ethinyl estradiol and cyproterone acetate in the treatment of menstrual irregularities of hyper-androgenic origin.
- Conditions
- Amenorrhea, Dysmenorrhea, Menstruation Disturbances, Hyperandrogenism
- Trial name
- NCT01103518
- Testing
- Ethinyl Estradiol + Cyproterone acetate
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Fundação Educacional Serra dos Órgãos
Stress Urinary Incontinence, Urinary Incontinence
Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence
This is a multicentered, double-blind, randomized controlled, surgical trial of 358 women with inadequate symptom relief of stress urinary incontinence (SUI) or stress predominant mixed urinary incontinence (MUI) after…
- Conditions
- Stress Urinary Incontinence, Urinary Incontinence, Mixed Urinary Incontinence
- Trial name
- BASIS (NCT06480227)
- Testing
- Solyx Single-incision Sling, Bulkamid Transurethral Bulking Agent
- Where
- 7 sites in United States
- Volunteers
- 358 people
- Sponsor
- NICHD Pelvic Floor Disorders Network