Clinical trials: Pelvic Endometriosis
Endometriosis
A Study to Evaluate Safety and Efficacy of Elagolix in Participants With Endometriosis With Associated Moderate to Severe Pain
This is a Phase 3, dose-escalation study designed to evaluate the safety and efficacy of both elagolix alone and elagolix plus estradiol/norethindrone acetate (E2/NETA) over 24 months in the management of endometriosis with…
- Trial name
- NCT03343067
- Testing
- elagolix, estradiol/norethindrone acetate (E2/NETA)
- Where
- 37 sites in United States
- Volunteers
- 11 people
- Sponsor
- AbbVie
Endometriosis, Pelvic Pain
The Effectiveness of Lng IUD for Treatment of the Patient Undergone Conservative Surgery for Pelvic Endometriosis
this study is to determine whether the frequency and severity of pelvic pain or dysmenorrhea are reduced in women with symptomatic endometriosis in whom a Lng IUD is inserted after operative laparoscopy compare with those treated…
- Conditions
- Endometriosis, Pelvic Pain, Dysmenorrhea
- Trial name
- NCT00455845
- Testing
- Levonorgestrel IUD
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Endometriosis, Chronic Pelvic Pain
A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirmed Endometriosis and the Impact on the Disease or Symptom Progression.
This study will describe historic, current, and evolving treatment pathways, treatments, and interventions in women with a suspected or confirmed diagnosis of endometriosis in order to better understand the impact of early…
- Conditions
- Endometriosis, Chronic Pelvic Pain, Dysmenorrhea
- Trial name
- NCT04140175
- Where
- 117 sites in United States
- Volunteers
- 291 people
- Sponsor
- AbbVie
Endometriosis
Safety and Efficacy Study to Evaluate Proellex in the Treatment of Premenopausal Women With Symptomatic Endometriosis
The purpose of this study is to determine whether Proellex is safe and effective for the treatment of symptomatic endometriosis.
- Trial name
- NCT00556075
- Testing
- Proellex 25 mg, Proellex 50 mg
- Where
- 17 sites in United States
- Volunteers
- 67 people
- Sponsor
- Repros Therapeutics Inc.
Novel MRI Technique
Functional Evaluation of Brain Pain Centers in Endometriosis-Associated Chronic Pelvic Pain Exploring the Impact of Central Sensitization Using a Novel MRI Technique
Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterus, affecting about 10% of reproductive-age women.
- Trial name
- NCT06720181
- Testing
- MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Endometriosis, Adenomyosis
Assessing the Mechanisms and Impact of a Novel Cannabinoid Product for Gynecologic Pain
Despite recent increases in both medical and recreational cannabis use in the United States and globally, little research has been conducted to determine the potential applications for womens health.
- Conditions
- Endometriosis, Adenomyosis, Chronic Pelvic Inflammatory Disease
- Trial name
- PAIN-GP (NCT07728695)
- Testing
- Custom-formulated, high-CBD study product
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Staci Gruber, Ph.D.
Pelvic Neoplasms, Endometriosis
Cohort of Patients With Pelvic Gynecological Cancer: Constitution of a Collection of Biological Samples With Radioclinical Characterization
The management of pelvic gynecological cancers (PGC) is based on the determination of extension to guide treatments. The biology of the CGP is constantly evolving and personalized medicine adapted to this biology is currently in…
- Trial name
- PELVIMASS2 (NCT03622983)
- Testing
- collection of sample and data
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Endometriosis, Adenomyosis
Efficacy of Acupuncture on Chronic Pelvic Pain in Women With Endometriosis or Adenomyosis
The purpose of ths study is to determine the efficacy of acupuncture on chronic pelvic pain in women with endometriosis or adenomyosis.
- Conditions
- Endometriosis, Adenomyosis, Pelvic Pain
- Trial name
- NCT01259180
- Testing
- acupuncture treatment
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- East West Neo Medical Center
Endometriosis
Study of Real Clinical Practice to Evaluate the Effects of Oral Dydrogesterone for Treatment of Confirmed Endometriosis
A non-interventional, observational program to assess the effects of dydrogesterone (Duphaston®) 6-months-administration in patients with confirmed endometriosis in a post-marketing setting in the Russian Federation
- Trial name
- NCT03690765
- Testing
- Duphaston® (Dydrogesterone)
- Where
- 21 sites in Russia
- Volunteers
- 350 people
- Sponsor
- Abbott
Deep Endometriosis
Efficacy of Double Contrast-enhanced Ultrasound of Pelvic in Preoperative Evaluation of Deep Endometriosis
Endometriosis occurs in about 10-15% of women of childbearing age and is a major cause of infertility and dysmenorrhea. Deep endometriosis is the most serious manifestation of endometriosis, which often affects the quality of…
- Trial name
- NCT05540821
- Testing
- Hysterosalpingo-contrast sonography and sonoPODography
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Shenzhen Second People's Hospital
Endometriosis, Pelvic Pain
Estradiol-mediated Inflammation and Central Sensitization in the Pathophysiology of Endometriosis-associated Pelvic Pain
The purpose of this study is to better understand how hormone suppression with Relugolix Combination-Therapy (CT) affects pelvic pain, inflammation, and pain sensitivity in women with moderate-to-severe endometriosis associated…
- Trial name
- NCT07100782
- Testing
- Relugolix CT
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Michigan
Endometriosis
A Study to Assess the Effectiveness and Safety of Different Doses of ASP1707 Compared to Placebo for Endometriosis Associated Pelvic Pain
The main objective for this study is to assess the efficacy and dose-response relationship of ASP1707 in reduction of endometriosis associated pelvic pain.
- Trial name
- NCT01767090
- Testing
- ASP1707, Leuprorelin acetate
- Where
- 85 sites in Belgium, Bulgaria and 7 more
- Volunteers
- 912 people
- Sponsor
- Astellas Pharma Europe B.V.
Endometriosis
Relaxin, Matrix Metalloproteinase-2 and Interleukin-6 in Women With Chronic Pelvic Pain
In our study, by evaluating the serum and vaginal-peritoneal fluid levels of Relaxin, Matrix Metalloproteinase-2 and Interleukin-6 in women over 35 years of age with chronic pelvic pain, the investigators aimed to reveal their…
- Trial name
- NCT06628479
- Testing
- interleukin, enzyme, hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Endometriosis
ENDOGYM: A Holistic Approach With Pelvic Floor Physiotherapy and Yoga for Endometriosis Pain Relief
The aim of this study is to evaluate the combined effects of Yoga practice and pelvic floor physiotherapy (PFP) on chronic pelvic pain (CPP) and dyspareunia in endometriosis patients.
- Trial name
- ENDOGYM (NCT07245537)
- Testing
- Yoga, Pelvic Floor Physiotherapy
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Endometriosis
Endometriosis Trial: Study of NBI-56418 in Endometriosis
This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group study with subjects randomized to one of three treatment groups, placebo, 75 mg and 150 mg in a 1:1:1 ratio.
- Trial name
- NCT00109512
- Testing
- NBI-56418 (GnRH antagonist)
- Where
- 15 sites in United States
- Volunteers
- 76 people
- Sponsor
- Abbott
Endometriosis, Pain
Efficacy Study of Atorvastatin in Pelvic Pain Relief in Women With Endometriosis
The purpose of this study is to determine whether atorvastatin (alone or in combination with oral contraceptive) is effective in treatment of pelvic pain and inflammatory response in women with endometriosis.
- Trial name
- EndoStatin (NCT00675779)
- Testing
- oral contraceptive (Mercilon), atorvastatin + oral contraceptive
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Poznan University of Medical Sciences
Pelvis Pain Chronic, Endometriosis of Uterus
Functional Brain Imaging and Psychological Testing in Women With Chronic Pelvic Pain
Functional magnetic resonance imaging in women with chronic pelvic pain using arterial spin labelling, functional connectivity, diffusion tensor imaging and magnetic resonance spectroscopy.
- Trial name
- NCT02160483
- Testing
- Functional magnetic resonance imaging
- Where
- Singapore
- Sponsor
- KK Women's and Children's Hospital
Endometriosis, Chronic Pain
Evaluation of Yoga and Conventional Physical Exercise for Pain and Quality of Life in Women With Endometriosis: A Randomized Clinical Trial
two-arm randomized parallel-group trial comparing an 8-week online yoga program versus a conventional physical exercise program.
- Conditions
- Endometriosis, Chronic Pain, Dysmenorrhea, Dyspareunia
- Trial name
- NCT07424859
- Testing
- YOGA, physical exercise
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Dysmenorrhea
Efficacy and Safety,Long-term Study of Low-dose Oral Contraceptive Pill to Treat Dysmenorrhea.
The purpose of this long-term study is to determine whether combination oral contraceptive pill of Norethindrone \& Ethinyl estradiol is effective in the treatmentof dysmenorrhea associated with endometriosis.
- Trial name
- NCT00212277
- Testing
- Norethindrone,Ethinyl Estradiol
- Sponsor
- Nobelpharma
Endometriosis
Anastrazole Plus GnRH-agonist in the Treatment of Endometriosis Recurrence
The aromatase inhibitor (anastrazole) plus long acting GnRH agonist leuprolide acetate will be tested for the treatment of women with endometriosis recurrence compared with classical GnRH analog treatment.
- Trial name
- NCT01769781
- Testing
- anastrazole, GnRH analog alone
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy