Clinical trials: Pelvic Endometriosis
Endometriosis
Safety and Efficacy Study to Evaluate Proellex in the Treatment of Premenopausal Women With Symptomatic Endometriosis
The purpose of this study is to determine whether Proellex is safe and effective for the treatment of symptomatic endometriosis.
- Trial name
- NCT00556075
- Testing
- Proellex 25 mg, Proellex 50 mg
- Where
- 17 sites in United States
- Volunteers
- 67 people
- Sponsor
- Repros Therapeutics Inc.
Endometriosis
A Study to Evaluate the Safety and Effectiveness of Three Asoprisnil Doses in the Treatment of Women With Endometriosis
The objective of this study is to determine the safety and effectiveness of three doses of asoprisnil, compared to placebo, in the treatment of women with endometriosis.
- Trial name
- NCT00160446
- Testing
- Asoprisnil
- Volunteers
- 130 people
- Sponsor
- Abbott
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Dysmenorrhea, Pelvic Pain
Continuous Versus Cyclic Oral Contraceptives for Endometriosis
To evaluate the efficacy of oral contraceptives in a continuous fashion versus the usual cyclic fashion in the recurrence of endometriosis related symptoms and endometriomas following fertility-sparing surgery.
- Conditions
- Dysmenorrhea, Pelvic Pain, Dyspareunia, Endometrioma
- Trial name
- NCT02237131
- Testing
- Oral contraceptives cyclic, Oral contraceptives continuous
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Athens
Endometriosis
Evaluation of DR-2001 for the Management of Endometriosis-Related Pelvic Pain
This is a 3-arm, multicenter, double-blind, randomized, placebo-controlled study to evaluate the efficacy of DR-2001 in endometriosis-related symptoms, primarily nonmenstrual pelvic pain, over a 12-week treatment period.
- Trial name
- NCT00117481
- Testing
- DR-2001a, DR-2001b
- Where
- 41 sites in United States
- Volunteers
- 90 people
- Sponsor
- Duramed Research
Endometriosis
MY-ENDO -- Mind Your ENDOmetriosis: a Digital Mindfulness- and Acceptance-based Endometriosis Self-management Program
The purpose of the study is to assess the effect of a digital mindfulness- and acceptance-based psychological intervention on quality of life, work ability, pain experience and physical and mental health in participants…
- Trial name
- NCT06211231
- Testing
- Digitally delivered mindfulness- and acceptance-based psychological intervention
- Where
- 2 sites in Denmark
- Volunteers
- 255 people
- Sponsor
- University of Aarhus
Pelvic Pain, Endometriosis
Endometriosis Pain
Aim 1. To determine the factors contributing to pain in patients with chronic pelvic pain with and without endometriosis Aim 2. To determine the changes following endometriosis lesion removal surgery in pain and sex hormone…
- Trial name
- NCT06101303
- Testing
- Psychophysical assessment, Psychophysical assessments of experimental pain, Blood, urine and saliva samples
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Washington University School of Medicine
Endometriosis, Chronic Pelvic Pain Syndrome
Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study
The goal of this randomized controlled trial is to investigate the effect of esketamine versus placebo on the NRS score for chronic pelvic pain.
- Trial name
- EASYlight (NCT06161805)
- Testing
- Esketamine hydrochloride
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Reinier de Graaf Groep
Endometriosis, Pelvic Pain
Use of TENS Unit in the Management of Endometriosis Pain
The purpose of this study is see if Transcutaneous Electrical Nerve Stimulator (TENS) units help decrease endometriosis flare pain.
- Trial name
- NCT05348005
- Testing
- Ovira Transcutaneous Electrical Nerve Stimulation Unit
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Endometriosis, Pelvic Pain
Machine Learning for Early Diagnosis of Endometriosis(MLEndo)
The project aims to create a large prospective data bank using the Lucy medical mobile application and collect and analyze patient profiles and structured clinical data with artificial intelligence.
- Conditions
- Endometriosis, Pelvic Pain, Infertility, Female
- Trial name
- MLEndo (NCT06147687)
- Testing
- Self reported data collection
- Where
- 2 sites in Hungary
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Deep Endometriosis
Efficacy of Double Contrast-enhanced Ultrasound of Pelvic in Preoperative Evaluation of Deep Endometriosis
Endometriosis occurs in about 10-15% of women of childbearing age and is a major cause of infertility and dysmenorrhea. Deep endometriosis is the most serious manifestation of endometriosis, which often affects the quality of…
- Trial name
- NCT05540821
- Testing
- Hysterosalpingo-contrast sonography and sonoPODography
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Shenzhen Second People's Hospital
Endometriosis
Study Evaluating the Safety and Efficacy of Proellex® in the Treatment of Endometriosis-extension Study
ZPE-201 Extension of treatment
- Trial name
- NCT00958412
- Testing
- Proellex®
- Where
- 8 sites in United States
- Volunteers
- 18 people
- Sponsor
- Repros Therapeutics Inc.
Dysmenorrhea, Menstrual Pain
Vaginal Sildenafil for Primary Dysmenorrhea
This open-label, non-randomized mechanistic study will evaluate whether a single 100 mg vaginal sildenafil citrate suppository reduces uterine hypercontractility during menstruation in adults with moderate-to-severe dysmenorrhea.
- Conditions
- Dysmenorrhea, Menstrual Pain, Endometriosis, Uterine Fibroid
- Trial name
- SILDYS (NCT07508358)
- Testing
- Sildenafil citrate vaginal suppository
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kevin Hellman
Chronic Pain, Pelvic Pain
Virtual Reality During Ultrasound Examination of Women With Endometriosis
To evaluate the effectiveness of VR as a distraction technique in the management of acute pain and anxiety during ultrasound exam in patients with endometriosis in the outpatient setting.
- Conditions
- Chronic Pain, Pelvic Pain, Endometriosis
- Trial name
- NCT04711408
- Testing
- SootheVR: AppliedVR, Los Angeles, California a head-mounted displa
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Endometriosis, Chronic Pelvic Pain
Pelvic Floor Muscle Function and Endometriosis-Related Pelvic Pain
Our study aims to investigate the associations between endometriosis-related pelvic pain and pelvic floor muscle strength, endurance, and relaxation ability, as well as quality of life, physical activity, and the presence of…
- Conditions
- Endometriosis, Chronic Pelvic Pain, Pelvic Pain Associated With Endometriosis or Adenomyosis
- Trial name
- NCT07713108
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Woman, Pelvic Pain
The Effect of Emotional Freedom Techniques on Pelvic Pain
Pelvic pain caused by endometriosis is a common symptom and reduces women's quality of life. EFT is a method that can be preferred in pelvic pain due to its ease of use and low cost. Raising women's awareness for EFT
- Trial name
- NCT06429254
- Testing
- Experimental group
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Endometriosis, Chronic Pelvic Pain
A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirmed Endometriosis and the Impact on the Disease or Symptom Progression.
This study will describe historic, current, and evolving treatment pathways, treatments, and interventions in women with a suspected or confirmed diagnosis of endometriosis in order to better understand the impact of early…
- Conditions
- Endometriosis, Chronic Pelvic Pain, Dysmenorrhea
- Trial name
- NCT04140175
- Where
- 117 sites in United States
- Volunteers
- 291 people
- Sponsor
- AbbVie
Endometriosis
Endometriosis Pelvic Pain Interdisciplinary Cohort Data Registry
The purpose of this data registry is to prospectively collect data from patients referred to an interdisciplinary clinic for pelvic pain and endometriosis to investigate long-term patient outcomes, prognosis, predictors, causes…
- Trial name
- EPPIC (NCT02911090)
- Testing
- Data Registry
- Where
- Canada
- Volunteers
- 5,000 people
- Sponsor
- BC Women's Hospital & Health Centre
Chronic Pelvic Pain, Endometriosis
Research on the Impact of Chronic Pelvic Pain on Endometriosis
Chronic pelvic pain (CPP) is a common disease with multiple systems and multiple causes. In recent years, the incidence rate of CPP in women has gradually increased.
- Trial name
- NCT06584760
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Endometriosis
Efficacy of Injectable Contraceptive and Oral Contraceptive Administered After Surgical Treatment of Endometriosis With Pain
Patients with endometriosis-associated pain have conservative surgery performed to remove all visible lesions. Then, patients are randomized into two groups.
- Trial name
- NCT01056042
- Testing
- intramuscular depot medroxyprogesterone acetate, ethinyl estradiol 30 micrograms, gestodene 75 micrograms
- Where
- Thailand
- Volunteers
- 112 people
- Sponsor
- Prince of Songkla University