Clinical trials: Pelvic MRI
Urinary Incontinence
Functional Assessment and Muscle Evaluation Through Exercise Trial
The purpose of this study is to decrease rates of urinary incontinence in older women by building strength in the pelvic and lower body muscle through exercise and rehabilitation.
- Trial name
- FAME (NCT03166150)
- Testing
- Multi-modal rehabilitation program, Pelvic Floor Physical therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Howard University
Inflammatory Bowel Disease, Neoplastic Pathology
Assessment of MRI Tractography for Pelvic Floor Sphincter Analysis
Urinary and faecal incontinences generally come from a dysfunction of the pelvic floor muscles, and more particularly the sphincters. Among other causes, they may be related to accidental trauma, obstetric or iatrogenic.
- Trial name
- TractoCA (NCT03881436)
- Testing
- MRI with DTI sequence
- Where
- France
- Volunteers
- 23 people
- Sponsor
- IHU Strasbourg
Locally Advanced Rectal Cancer
SMART TNT for the Conservative Management of Locally Advanced Rectal Cancer
The purpose of this research study is to find out how safe and effective is treating patients with locally advanced rectal cancer (LARC) with chemotherapy first and then follow with radiation therapy to a higher dose than what is…
- Trial name
- SMART TNT (NCT05412082)
- Testing
- Intensity-modulated radiation therapy, 5-fluorouracil, Leucovorin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Miami
Uterine Neoplasms, Cervix Neoplasms
Combidex USPIO - Ultra-small Superparamagnetic Iron Oxide
The purpose of this study is to test whether or not a new contrast agent called Combidex, a contrast agent formulated from ultra-small superparamagnetic iron oxide (USPIO) improves the ability of Magnetic Resonance Imaging (MRI)…
- Conditions
- Uterine Neoplasms, Cervix Neoplasms, Bladder Neoplasms, Prostatic Neoplasms
- Trial name
- NCT00188695
- Testing
- MRI contrast agent Combidex (ferumoxtran-10)
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- University Health Network, Toronto
Healthy Volunteers
Assessment of Magnetic Resonance Imaging Neurography and Tractography for Preoperative Mapping of Pelvic Nerves
This project aims at assessing two MRI acquisition methods, neurography and tractography, for the visualization of pelvic nerves.
- Trial name
- Neuro-Tracto (NCT02582346)
- Testing
- MRI acquisition - no contrast agent
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IHU Strasbourg
Dysmenorrhea, Menstrual Pain
Vaginal Sildenafil for Primary Dysmenorrhea
This open-label, non-randomized mechanistic study will evaluate whether a single 100 mg vaginal sildenafil citrate suppository reduces uterine hypercontractility during menstruation in adults with moderate-to-severe dysmenorrhea.
- Conditions
- Dysmenorrhea, Menstrual Pain, Endometriosis, Uterine Fibroid
- Trial name
- SILDYS (NCT07508358)
- Testing
- Sildenafil citrate vaginal suppository
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kevin Hellman
Symptomatic Uterine Leiomyomas, Fibroids
The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids.
The primary goal of this study is to compare the safety and effectiveness of two standard fibroid treatments: MRI guided ultrasound surgery (MRgFUS) and uterine artery embolization (UAE).
- Conditions
- Symptomatic Uterine Leiomyomas, Fibroids, Uterine Fibroids, Myomas
- Trial name
- NCT00995878
- Testing
- Focused ultrasound (MRgFUS), Uterine artery embolization (UAE)
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Mayo Clinic
Endometriosis
Pelvic Endometriosis: Correlation of US and MRI With Laparoscopic Findings
Endometriosis is classically defined as the presence of endometrial glands and stroma outside the uterine cavity and its musculature. The definition of deep endometriosis is based on anatomic assumptions that may prove erroneous.
- Trial name
- NCT03860909
- Volunteers
- 30 people
- Sponsor
- Assiut University