Clinical trials: Pelvic Neoplasms
Cervical Cancer
Weekly IV Topotecan and Cisplatin With Radiation in Cervical Carcinoma
There will be approximately 14,000 new patients with invasive cervical cancer diagnosed in the United States in 2003 with about 4,000 deaths from this disease.
- Trial name
- NCT00257816
- Testing
- Topotecan, Cisplatin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, Irvine
Prostate Cancer
Evaluating the Impact of Prostate Only Versus Pelvic Radiation for N+ Prostate Cancer.
At least 40% of the patients with prostate cancer (PC) present with positive lymph nodes (N1). The optimal treatment strategy for these patients remains controversial.
- Trial name
- PROPER (NCT02745587)
- Testing
- radiotherapy
- Where
- Belgium
- Volunteers
- 69 people
- Sponsor
- University Hospital, Ghent
Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma
Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer
This randomized phase III trial is studying cisplatin, radiation therapy, and tirapazamine to see how well they work compared to cisplatin and radiation therapy in treating patients with cervical cancer.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma, Cervical Squamous Cell Carcinoma, Stage IB Cervical Cancer
- Trial name
- NCT00262821
- Testing
- cisplatin, tirapazamine
- Where
- 282 sites in United States, Canada
- Volunteers
- 402 people
- Sponsor
- National Cancer Institute (NCI)
Polycystic Ovarian Syndrome
Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome.
The study will be a non-blinded randomized controlled trial, consisting of two groups. Non-probability Convenience sampling will be used to recruit participants who will meet the inclusion criteria.
- Trial name
- NCT07645014
- Testing
- Neurodynamic stretches, myofascial pain release technique Interventions:
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Prostate Cancer Metastatic, Prostate Cancer
Dutch National Randomized Study: PSMA-PET/CT As a Triage Tool for Pelvic Lymph Node Dissection in Prostatectomy Patients
To determine if the use of Prostate-Specific Membrane Antigen Positron Emission Computer Tomography (PSMA PET/CT) as a selection tool for performing extended lymph node dissection (ePLND) for prostate cancer (PCa) in the primary…
- Conditions
- Prostate Cancer Metastatic, Prostate Cancer, Lymph Node Metastases
- Trial name
- PSMA-SELECT (NCT05000827)
- Testing
- PSMA-PET/CT, Nomogram
- Where
- Netherlands
- Volunteers
- 706 people
- Sponsor
- Canisius-Wilhelmina Hospital
Pelvic Mass
Tranexamic Acid in Reducing Blood Loss in Patients With Pelvic Tumors Undergoing Hemipelvectomy Surgery
This early phase I trial studies how well tranexamic acid works in reducing the loss of blood in patients with pelvic tumors undergoing hemipelvectomy surgery.
- Trial name
- NCT03128866
- Testing
- Hemipelvectomy, Tranexamic Acid
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Palliative Care
Radiotherapy in Palliation of Advanced Pelvic Cancer
The study wants to define the safety and efficacy of a short-course radiation therapy in patients with symptomatic advanced pelvic cancer.
- Trial name
- NCT03947268
- Testing
- Short course radiotherapy
- Volunteers
- 25 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
R115777 in Treating Patients With Advanced Bladder Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of R115777 in treating patients who have advanced bladder…
- Trial name
- NCT00006376
- Testing
- chemotherapy, tipifarnib
- Where
- 2 sites in United States
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Sexual Dysfunction, Pelvic Floor Disorders
Improving Women's Function After Pelvic Radiation
The purpose of the study is to develop and test an intervention combining physical therapy (PT) and coping skills training to improve women's sexual function after pelvic radiation.
- Conditions
- Sexual Dysfunction, Pelvic Floor Disorders, Gynecologic Cancer
- Trial name
- NCT04544735
- Testing
- Integrated Physical Therapy and Coping Skills Training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Rectal Cancer
Pelvic Drain After Rectal Resection for Mid-low Rectal Cancer
This RCT aims at assessing the effects of a pelvic drain after total mesorectal excision for mid-low rectal cancer on the rates of pelvic sepsis and anastomotic leaks.
- Trial name
- GECO1 (NCT04573621)
- Testing
- Pelvic drain, No pelvic drain is placed
- Where
- Spain
- Volunteers
- 518 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pelvic Cancer, Abdominal Cancer
Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries.
The investigators hypothesize that effect of addition of dexmedetomidine or ketamine by IV infusion to lidocaine infusion may be more beneficial than lidocaine infusion alone on proinflammatory cytokines (IL-1, IL-6 and TNFα)…
- Conditions
- Pelvic Cancer, Abdominal Cancer, Surgery, Proinflammatory Cytokines
- Trial name
- NCT06631625
- Testing
- Lidocaine Intravenous Infusion, Lidocaine and ketamine, lidocaine and dexmedetomidine infusion
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University
Prostate Cancer
Safety Study of a Shorter (Hypofractionated) Radiotherapy for the Prostate Bed With or Without the Pelvic Lymph Nodes
This trial investigates safety and feasibility of a hypofractionated radiotherapy (i.e. with higher daily doses and shorter total treatment time compared to standard fractionation) of the prostate bed with or without the pelvic…
- Trial name
- PRIAMOS (NCT01620710)
- Testing
- hypofractionated helical IMRT
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Heidelberg University
Prostate Cancer
Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer
This is a single-arm phase II prospective trials that is recruiting 100 participants. The study population that is being investigated are patients with localized high-risk or node-positive prostate cancer.
- Trial name
- MOB-RT (NCT05313815)
- Testing
- Moderate hypofractionated boost to the prostate with pelvic RT (external beam radiotherapy)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer, Cervix Cancer
Medico-economic Evaluation of IMRT by Hi Art, RapidArc, VMAT Therapy in Prostate, Cervix and Anal Canal Cancers
The aim of the study is a medico-economic evaluation to estimate a cost differential between three modalities of Intensity-Modulated Radiation Therapy for cancers of the prostate, cervix and anal canal with pelvic lymph node…
- Conditions
- Prostate Cancer, Cervix Cancer, Anal Canal Cancers
- Trial name
- RCMI-PELVIS (NCT01325961)
- Testing
- IMRT using Rapid Arc - prostate cancer, IMRT using Rapid Arc - Anal canal cancer, IMRT using Rapid Arc - Cervix cancer
- Where
- 15 sites in France
- Volunteers
- 215 people
- Sponsor
- Institut Cancerologie de l'Ouest
Ovarian Cancer
Pelvic and Aortic-cava Lymphadenectomy Randomized for Ovarian Cancer
It is a multicenter randomized trial of superior cleaning compared the absence of dissection in stage III patients with optimal surgical resection without retroperitoneal lymph node palpable.
- Trial name
- CARACO (NCT01218490)
- Testing
- ovarian cancer surgery
- Where
- 19 sites in France
- Volunteers
- 450 people
- Sponsor
- Institut Cancerologie de l'Ouest
Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter, Recurrent Bladder Cancer
Phase II Trial Of PS-341 (Bortezomib) In Patients With Previously Treated Advanced Urothelial Tract Transitional Cell Carcinoma
Bortezomib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. This phase II trial is studying how well bortezomib works in treating patients with advanced transitional cell carcinoma of…
- Conditions
- Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter, Recurrent Bladder Cancer, Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter, Recurrent Urethral Cancer
- Trial name
- NCT00072150
- Testing
- bortezomib
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute (NCI)
Urinary Incontinence
Improving Urinary Continence and Quality of Life in Prostate Cancer Patients
This intervention program combines biofeedback PFME with a telephone or support group intervention to treat persistent urinary incontinence (UI).
- Trial name
- NCT01365182
- Testing
- BF+SUPPORT, BF+PHONE
- Volunteers
- 279 people
- Sponsor
- Case Western Reserve University
Pelvic Tumor
SGO Society of Gynecologic Oncologists Data Outcomes Project
SGO Society of Gynecologic Oncologists Data Outcomes Project.
- Trial name
- NCT00320996
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of New Mexico
Pelvis Tumors
IMRT Followed by CyberKnife Boost Focused on the Gross Residual Pelvic Tumor Volume
The present register has been designed to confirm the hypothesis that while using high quality Intensity Modulated Radiation Techniques (IMRT) and a reduced external beam stereotactic boost component it would be possible to…
- Trial name
- Boost_Pelvis (NCT03206385)
- Testing
- Radiation treatment, CK Boost Pelvis
- Where
- Luxembourg
- Volunteers
- 120 people
- Sponsor
- Centre Francois Baclesse, Luxembourg
Recurrent Bladder Urothelial Carcinoma, Recurrent Renal Pelvis Urothelial Carcinoma
Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial Cancer
This phase II trial studies how well erlotinib hydrochloride works in Treating participants with muscle invasive urothelial cancer or urothelial cancer that has come back.
- Conditions
- Recurrent Bladder Urothelial Carcinoma, Recurrent Renal Pelvis Urothelial Carcinoma, Recurrent Ureter Urothelial Carcinoma, Recurrent Urethral Urothelial Carcinoma
- Trial name
- NCT00749892
- Testing
- Erlotinib Hydrochloride
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- M.D. Anderson Cancer Center