Clinical trials: Pelvic Neoplasms
Urothelial Carcinoma of the Renal Pelvis and Ureter, Transitional Cell Cancer of the Renal Pelvis and Ureter
Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma
The goal of this prospective clinical trial is to investigate the safety and efficacy of ST-02 (mucoadhesive gemcitabine suspension for pyelocaliceal instillation) to treat Upper Tract Urothelial Carcinoma (UTUC) in participants…
- Trial name
- NCT06124976
- Testing
- ST-02
- Where
- 8 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Peter Black
Carcinoma, Transitional Cell, Urinary Bladder Neoplasms
A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer
This is a study that will test how an experimental drug (enfortumab vedotin) affects patients with cancer of the urinary system (urothelial cancer).
- Conditions
- Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Urologic Neoplasms, Renal Pelvis Neoplasms
- Trial name
- EV-201 (NCT03219333)
- Testing
- Enfortumab vedotin
- Where
- 81 sites in United States, France and 6 more
- Volunteers
- 219 people
- Sponsor
- Astellas Pharma Inc
Dysmenorrhea Primary, Dysmenorrhea
Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25
85 percent of women of reproductive age experience consistent period cramps/menstrual pain, and 60% indicate that they do not use painkillers to relieve menstrual symptoms; there is a need for natural and non-medicative…
- Conditions
- Dysmenorrhea Primary, Dysmenorrhea, Menstrual Discomfort, Menstrual Problem
- Trial name
- NUTRITION; GYN (NCT06227676)
- Testing
- Cramp Bites by Aunt Flo's Kitchen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cornell University
Colorectal Cancer
Concurrent Chemoradiation Versus Wide Pelvic Lymphadenectomy for Advanced Rectal Cancer
Based on the neurophysiology, it is well known that sympathetic nerves control the ejaculatory function and bladder neck closure. In contrast, the parasympathetic nerves control penile erection and bladder wall contraction.
- Trial name
- NCT00154752
- Testing
- CCRT, Pelvic lymphadenoectomy.
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Advanced Prostate Cancer
SRAM study_Postate Cancer
This is a phase 2 randomized study for High risk localized prostate cancer (T3 to T4 disease and/or PSA > 20 and/or Gleason score ≥ 8) without evidence of distant and nodal metastasis.
- Trial name
- NCT03938649
- Testing
- Conventional IMRT, SBRT
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- CCTU
Pelvic Neoplasms, Endometriosis
Cohort of Patients With Pelvic Gynecological Cancer: Constitution of a Collection of Biological Samples With Radioclinical Characterization
The management of pelvic gynecological cancers (PGC) is based on the determination of extension to guide treatments. The biology of the CGP is constantly evolving and personalized medicine adapted to this biology is currently in…
- Trial name
- PELVIMASS2 (NCT03622983)
- Testing
- collection of sample and data
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Head and Neck Cancer, Breast Cancer
Evaluation of Improved Onboard Patient Imaging
The primary objective of radiation therapy is to deliver a therapeutic dose of radiation precisely to the target while minimizing exposure to healthy surrounding tissues.
- Conditions
- Head and Neck Cancer, Breast Cancer, Upper Gastrointestinal Cancer, Lung Cancer
- Trial name
- NCT06187103
- Testing
- HyperSight Imaging
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Varian, a Siemens Healthineers Company
Prostate Cancer
Study to Assess [177Lu]Lu-PSMA-R2 (AAA602) and [225Ac]Ac-PSMA-R2 (AAA802) in Participants With PSMA-positive HRLPC
The purpose of this trial is to learn more about the effects of AAA602 and AAA802 in men with prostate-specific membrane antigen (PSMA) positive high-risk localized prostate cancer (HRLPC) before surgery to remove the prostate…
- Trial name
- NeoPSMA (NCT06881823)
- Testing
- AAA602, AAA802, Gallium (68Ga) gozetotide
- Sponsor
- Novartis Pharmaceuticals
Malignant Female Reproductive System Neoplasm
Pelvic Floor Rehabilitation for Gynecological Cancer Patients
As cancer treatment improves, the cancer survivor's quality of life and level of function have gained increasing importance. Pelvic floor function is directly affected by gynecological cancer and treatment, and pelvic floor…
- Trial name
- NCT01871688
- Testing
- pelvic floor rehabilitation program with neuromodulation
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma
Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer
This randomized phase III trial studies pelvic radiation therapy to see how well it works compared with vaginal implant radiation therapy, paclitaxel, and carboplatin in treating patients with high-risk stage I or stage II…
- Conditions
- Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Fatigue, Neurotoxicity Syndrome
- Trial name
- NCT00807768
- Testing
- 3-Dimensional Conformal Radiation Therapy, Carboplatin, Intensity-Modulated Radiation Therapy
- Where
- 540 sites in United States, South Korea
- Volunteers
- 601 people
- Sponsor
- Gynecologic Oncology Group
Metastatic or Recurrent Lesions in the Spine, Metastatic or Recurrent Lesions in the Pelvis
Image-Guided Navigation for High Dose Rate Temporary Interstitial Brachytherapy in the Palliative Management of Previously Treated Tumors of the Spine and Pelvis
The purpose of this study is to see if using a form of imaging during surgery helps the doctors to guide the placement of radiation catheters more accurately.
- Trial name
- NCT01757717
- Testing
- Ir-192 high dose rate (HDR)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pathologic Fracture
Performance and Safety of the Innofix® Screw (IF25)
The purpose of this clinical investigation is to collect data about the safety and the performances of the InnoFix® screw : Clinical performances (Pain reduction due to the fracture treatment, maintenance of the stabilizaton of…
- Trial name
- IF25 (NCT06800417)
- Testing
- Percutaneous fixation by internal cemented screw (InnoFix®)
- Volunteers
- 34 people
- Sponsor
- Innoprod Medical
Cervical Cancer, Postoperative Pain
Laparoscopic vs Abdominal Radical Hysterectomy In Patients With Early Cervical Cancer
The purpose of this study is to determine whether laparoscopic radical hysterectomy for early cervical cancer will has decreased postoperative pain intensity compared to abdominal radical hysterectomy with similar postoperative…
- Trial name
- NCT01258413
- Testing
- Laparoscopic Radical Hysterectomy + pelvic lymphadenectomy, Abdominal radical hysterectomy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
High-risk Prostate Cancer, Prostate Cancer
Ga-68-PSMA-11 in High-risk Prostate Cancer
This will be an open-label, single-arm, rater-blinded, multicenter, diagnostic phase 1/2 study to assess safety and diagnostic performance of Ga-68-PSMA-11 positron emission tomography / computer tomography (PET/CT) imaging to…
- Conditions
- High-risk Prostate Cancer, Prostate Cancer, Prostate Cancer Metastatic, Lymphnode Metastasis
- Trial name
- NCT03362359
- Testing
- Ga-68-PSMA-11
- Where
- 8 sites in Austria, Germany
- Volunteers
- 173 people
- Sponsor
- German Cancer Research Center
Locally Advanced Rectal Cancer
Assess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC（AK104-IIT-13）
This study is a single-arm, open-label, multicenter clinical study to evaluate the efficacy and safety of preoperative short-course radiotherapy combined with AK104 and chemotherapy + TME surgery in patients with advanced rectal…
- Trial name
- AK104-IIT-13 (NCT05794750)
- Testing
- AK104 injection, TME surgery, Capecitabine
- Volunteers
- 50 people
- Sponsor
- JIN JING
Uterine Cervical Neoplasms, Laparoscopic Surgical Procedures
2D Versus 3D Radical Laparoscopic Hysterectomy for Cervical Cancer: a Prospective Randomized Trial
The aim of this prospective randomized pilot study is to verify if the operative time of a Radical abdominal hysterectomy (LRH) with pelvic lymphadenectomy for early stage cervical cancer (FIGO stages IA2-IB1-IIA<2cm) and for…
- Trial name
- NCT02320578
- Testing
- 3D Laparoscopy, Standard Laparoscopy
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Catholic University of the Sacred Heart
Cervical Cancer, Endometrial Cancer
Pelvic Fractures and Radiation Therapy for Cervical Cancer
The goal of this study is to estimate how often pelvic fractures occur in women treated with radiation therapy for either newly diagnosed or recurrent cervical, endometrial, or vaginal cancer.
- Conditions
- Cervical Cancer, Endometrial Cancer, Vaginal Cancer
- Trial name
- NCT00800644
- Testing
- CT or MRI + Blood Test
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- M.D. Anderson Cancer Center
Abdominal Tumor, Pelvic Tumor
Daily Adjustment of the Radiation Dose in MRI-guided Stereotactic Radiotherapy for Tumors in the Abdominal and Pelvic Regions
SBRT delivers high-dose radiation to precisely defined target volumes and is an effective locally ablative treatment option for both primary tumours and oligometastases in various settings, including lesions in the abdomen or…
- Trial name
- ACTION (NCT07687147)
- Testing
- SBRT with adaptive fractionation, Standard of Care (SOC)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Incontinence, Prostate Cancer
Urology Database to Evaluate Clinical Information and Improve Patient Care.
The purpose of initiating the Urology Database is to evaluate the outcomes of urology procedures and medical management to enhance the care and treatment of urology patients.
- Conditions
- Incontinence, Prostate Cancer, Interstitial Cystitis, Urinary Retention
- Trial name
- NCT00376298
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Kenneth Peters, MD
Cervical Cancer
Hypofractionated Whole Pelvic Chemoradiotherapy With iRex Optimization in Cervical Cancer
This study is a randomized controlled trial designed to compare hypofractionated whole pelvic radiotherapy with conventional radiotherapy in patients with cervical cancer undergoing concurrent chemoradiotherapy.
- Trial name
- HYPOCx-iRex (NCT07605507)
- Testing
- Hypofractionated Radiotherapy, Conventional Radiotherapy, Concurrent chemotherapy once a week
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Siriraj Hospital