Clinical trials: Pelvic Neoplasms
Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm
Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients
This early phase I trial studies how well heated intra-peritoneal chemotherapy with doxorubicin and cisplatin work for the treatment of abdominal or pelvic tumors that can be removed by surgery (resectable), does not respond to…
- Conditions
- Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm, Recurrent Colon Carcinoma, Recurrent Desmoplastic Small Round Cell Tumor
- Trial name
- TOASTIT (NCT04213794)
- Testing
- Cisplatin, Cytoreductive Surgery, Doxorubicin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Tumor
TRU-Cut Biopsy in Tumor cHaracterisation
Tru-cut biopsy (TCB) is a minimally invasive method to get an adequate sample from the lesion in order to tailor the appropriate management avoiding unnecessary surgery.
- Trial name
- TRUTH (NCT06816160)
- Testing
- tru-cut biopsy
- Where
- Czechia
- Volunteers
- 250 people
- Sponsor
- General University Hospital, Prague
Surgery--Complications, Pelvic Cancer
Reconstruction in Extended MArgin Cancer Surgery
Advanced pelvic cancers are uncommon, with treatment being challenging. Around 4000 patients every year need treatment in the UK. Cancers can involve multiple organs and often need radiotherapy and chemotherapy before surgery.
- Conditions
- Surgery--Complications, Pelvic Cancer, Abdominal Cancer, Quality of Life
- Trial name
- REMACS (NCT05219058)
- Testing
- Biological mesh reconstruction, Myocutaneous flap reconstruction, Primary closure reconstruction
- Where
- 18 sites in United Kingdom
- Volunteers
- 236 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Radiotherapy Induced Diarrhea, Acute Radiation Enteritis
Efficacy and Safety of Adjunctive Use of Rifaximin In Preventing Radiotherapy-induced Diarrhea in Cancer Patients
Preclinical data indicate that rifaximin could be repurposed as a novel strategy for preventing and reducing the severity of gastrointestinal damage, particularly diarrhea, that results from pelvic irradiation.
- Conditions
- Radiotherapy Induced Diarrhea, Acute Radiation Enteritis, Prostate Cancer, Cervical Adenocarcinoma
- Trial name
- NCT06783153
- Testing
- Rifaximin 550 MG, Standard Care Chemoradiation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Cancer Liver, Cancer Brain
Optimization of MRI for Radiation Therapy
Currently, appropriate patients undergo MRI imaging with immobilization and sequences optimized for diagnostic radiology purposes.
- Conditions
- Cancer Liver, Cancer Brain, Cancer Head &Neck, Cancer Pelvis
- Trial name
- NCT02045381
- Testing
- MRI Group
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Michigan Rogel Cancer Center
Malignancy, Metastasis
Same-session MR-only Simulation and Treatment With MRI-guided Adaptive Palliative RadioTherapy
This proposed study is unique in that patients will not undergo computed tomography (CT) simulation at any point during their treatment course and will instead have same-session magnetic resonance (MR)-only simulation and…
- Conditions
- Malignancy, Metastasis, Hemoptysis, Gastrointestinal Bleeding
- Trial name
- MAP-RT (NCT03824366)
- Testing
- Volumetric MR imaging, Radiation therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Total Exenteration, Anterior or Posterior Pelvic Exenteration
Quality of Life in Patients Undergoing Total Pelvic Exenteration
The purpose of this study is to learn more about the personal experiences of patients who are treated with pelvic exenteration surgery.
- Conditions
- Total Exenteration, Anterior or Posterior Pelvic Exenteration, Gynecologic Malignancies, Colorectal Malignancies
- Trial name
- NCT00597805
- Testing
- questionnaires/interviews
- Where
- 8 sites in United States
- Volunteers
- 94 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Pelvic Ring Tumor Lesions
Restoring Mobility: Roles of Percutaneous Consolidation for Pelvic Ring Bone Lesions
Evaluate early functional outcomes following percutaneous screw fixation or cementoplasty for pelvic ring tumor lesions.
- Trial name
- NCT06155890
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Urogynaecological Problem, Pelvic Floor Dysfunction, Cancer
Treatments for Urogynaecological Problems and Patient Selfreports
The research aims to assess the relationship between treatments for a range of urogynaecological problems (pelvic floor dysfunction, cancers) and patient reported values, psychological states, and quality of life.
- Trial name
- NCT02549157
- Testing
- Pelvic Floor Muscle Training
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Swansea University
Ureter Cancer, Renal Pelvic Carcinoma
Postoperative Adjuvant Immunotherapy Combined with Radiotherapy Versus Surgery Alone in Locally Advanced UTUC
This is a prospective cohort study to analyse the safety and efficacy of postoperative adjuvant radiotherapy combined with immunotherapy versus surgery alone group of UTUC patients with T3-4 stages or lymph nodes metastasis(N+)…
- Conditions
- Ureter Cancer, Renal Pelvic Carcinoma, Advanced Urothelial Carcinoma
- Trial name
- NCT06598761
- Testing
- Immunotherapy+radiotherapy, surveillance alone
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Prostate Cancer, Urinary Incontinence
Physical Therapy for Men Undergoing Prostatectomy
The purpose of this study is to determine if pelvic floor muscle training with a physical therapist before and after surgery will improve health-related quality of life following robot-assisted radical prostatectomy.
- Conditions
- Prostate Cancer, Urinary Incontinence, Pelvic Floor Physical Therapy
- Trial name
- NCT02558946
- Testing
- Pelvic Floor Muscle Physical Therapy, Control Group
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Indiana University
Oligometastatic Disease, Ureter Cancer
Radiotherapy Combined with Systemic Therapy Versus Systemic Therapy for Oligometastatic UTUCs
This study was a prospective, open-label, phase II randomised controlled clinical study, enrolling patients with primary oligometastatic uroepithelial carcinoma, oligometastasis was defined as ≤3 organs, and the number of…
- Conditions
- Oligometastatic Disease, Ureter Cancer, Renal Pelvic Carcinoma
- Trial name
- NCT06652022
- Testing
- Systematic therapy combined with radiotherapy, Systematic drug treatment
- Where
- 2 sites in China
- Volunteers
- 102 people
- Sponsor
- Peking University First Hospital
Abdominal Malignancy, Pelvic Malignancy
Intraoperative Radiation Therapy for Locally Advanced or Recurrent Abdomino-pelvic Solid Tumors With the CivaSheet
This study is a pilot study of the CivaSheet, a new type of intraoperative radiation therapy (IORT) device that offers several advantages over existing techniques of performing IORT.
- Trial name
- NCT02902107
- Testing
- CivaSheet, Brachytherapy, surgical resection
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Radiotherapy Side Effect, Pelvic Cancer
AI as an Aid for Weekly Symptom Intake in Radiotherapy
The study investigates the use of artificial intelligence (AI) and large language models (LLMs) to enhance the efficiency and accuracy of weekly treatment consultations (OTVs) in radiotherapy.
- Conditions
- Radiotherapy Side Effect, Pelvic Cancer, Patient
- Trial name
- NCT06525181
- Testing
- Generative Artificial Intelligence, Standard weekly symptom intake
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- jaide
Pelvic Cancer, Abdominal Cancer
Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries.
The investigators hypothesize that effect of addition of dexmedetomidine or ketamine by IV infusion to lidocaine infusion may be more beneficial than lidocaine infusion alone on proinflammatory cytokines (IL-1, IL-6 and TNFα)…
- Conditions
- Pelvic Cancer, Abdominal Cancer, Surgery, Proinflammatory Cytokines
- Trial name
- NCT06631625
- Testing
- Lidocaine Intravenous Infusion, Lidocaine and ketamine, lidocaine and dexmedetomidine infusion
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University
Sarcoma, Thoracic Cancer
Palliative Lattice Stereotactic Body Radiotherapy (SBRT) for Patients With Sarcoma, Thoracic, Abdominal, and Pelvic Cancers
This is a study evaluating the safety and efficacy of Lattice SBRT for patients with large tumors (≥ 4.5 cm) planning to undergo palliative radiotherapy.
- Conditions
- Sarcoma, Thoracic Cancer, Abdominal Cancer, Pelvic Cancer
- Trial name
- NCT04553471
- Testing
- Stereotactic body radiotherapy, Research blood draw
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Abdominal Cancer, Pelvic Cancer
Radiotherapy Treatments for Neoplasms in the Abdominal-pelvic Region
Evaluation of clinical and dosimetric aspects, tolerance, and effectiveness of abdominal-pelvic region radiotherapy treatments in patients undergoing radiotherapy for primary or secondary neoplasms localized in the…
- Trial name
- NCT06335238
- Where
- Italy
- Volunteers
- 7,700 people
- Sponsor
- European Institute of Oncology
Prevention, LARS - Low Anterior Resection Syndrome
Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)
The main aim of this randomized study will be to determine the effectiveness of pelvic floor exercises on the incidence or severity of LAR syndrome in patients after mini-invasive rectal resection.
- Conditions
- Prevention, LARS - Low Anterior Resection Syndrome, Pelvic Floor Disorders, Rectal Cancer
- Trial name
- CH1 (NCT06519006)
- Testing
- Pelvic floor exercise
- Where
- Slovakia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- F. D. Roosevelt University Hospital
Pelvic Cancer, Ovarian Cancer
Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses.
In a transvaginal tru-cut biopsy, guided by ultrasound, a needle is inserted through the vaginal wall into a pelvic lesion and a few pieces of tissue are obtained for examination.
- Conditions
- Pelvic Cancer, Ovarian Cancer, Cervical Cancer, Uterus Cancer
- Trial name
- NCT05610501
- Testing
- Ultrasound guided tru-cut biopsy
- Where
- 4 sites in Belgium, Czechia and 2 more
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Accuracy of Coplanar Template Assisted Seed Implantation for Abdominal and Pelvic Cancer
Accuracy of Coplanar Template Assisted Seed Implantation for Abdominal and Pelvic Cancer
In recent years, template guidance has been applied and developed in the field of puncture related operations, such as template-assisted radioactive seed implantation.
- Trial name
- NCT05483452
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Peking University Third Hospital