Clinical trials: Pelvic Neoplasms
Urinary Irritative/Incontinence Problems, Bowel Problems
Rehabilitation After Radiotherapy for Prostate Cancer
This project will test and evaluate a rehabilitation programme, which will empower the mens health and give them resources to face at new everyday life.
- Conditions
- Urinary Irritative/Incontinence Problems, Bowel Problems, Sexual Problems, Hormonal Problems
- Trial name
- RePCa (NCT01272648)
- Testing
- RePCa A
- Where
- Denmark
- Volunteers
- 161 people
- Sponsor
- Odense University Hospital
Pelvic Floor Disorder, Female Pelvic Floor Dysfunction
Late Side-effects After Cervical Cancer Treatment - Prevention and Treatment
Late side-effects following gynecological cancer are predominantly symptoms from the pelvic region originating from the bowels, urinary tract, lymphatic system, genitals and musculoskeletal system.
- Conditions
- Pelvic Floor Disorder, Female Pelvic Floor Dysfunction, Female Sexual Dysfunction, Female Urinary Incontinence
- Trial name
- NCT06786091
- Testing
- Pelvic floor muscle training rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 25 people
- Sponsor
- St. Olavs Hospital
Early Stage Ovarian Tumors, Peritoneal Carcinosis
PONDER: Pelvic Peritonectomy in Early Stage Ovarian Tumors
Early-stage ovarian tumors represent approximately 30% of all newly diagnosed ovarian cancers. Current international guidelines recommend random peritoneal biopsies for surgical staging, but the diagnostic yield of these biopsies…
- Trial name
- PONDER (NCT07271914)
- Testing
- systematic surgical approach to wider peritoneal biopsies according with dissection of retroperitoneal spaces, nerve-sparing approach, Histopathologic Analysis
- Where
- Italy
- Volunteers
- 390 people
- Sponsor
- Ospedale Santa Croce-Carle Cuneo
Perinatal Solid Tumors of the Thoraco-abdomino-pelvic Region
Perinatal Thoraco-abdomino-pelvic Tumors Study
Congenital tumors are a rare diagnosis in the fetus and newborn. They differ from those of children and adults in terms of the nature, location and evolution of the tumor.
- Trial name
- CONTRAST (NCT06365268)
- Testing
- Collection of data from the patient's medical file
- Where
- 5 sites in France
- Volunteers
- 152 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gynecologic Cancer, Pelvic Floor Disorders
Pelvic Floor Dysfunction and Aerobic Training in Gynecological Cancer
The incidence of gynecological cancer and the related death rates in the world are increasing every year. Unfortunately, pelvic floor disorders (PFDs) such as pelvic pain, dyspareunia, vaginal stenosis, and urinary incontinence…
- Conditions
- Gynecologic Cancer, Pelvic Floor Disorders, Aerobic Exercise
- Trial name
- NCT06406322
- Testing
- PFMT, Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Atılım University
Adnexal Mass
New Biomarkers Evaluating Ovarian Cancer
The purpose of this study is to evaluate new biomarkers for patients presenting to a physician for surgery to remove a mass in their pelvis and to continue to evaluate these types of patients using the ROMA algorithm for…
- Trial name
- NCT01466049
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- Fujirebio Diagnostics, Inc.
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Radiation Therapy Plus Cisplatin and Gemcitabine in Treating Patients With Cervical Cancer
This phase I trial is studying the side effects and best dose of gemcitabine when given together with radiation therapy and cisplatin in treating patients with cervical cancer that has not spread beyond the pelvis.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Small Cell Carcinoma, Cervical Squamous Cell Carcinoma
- Trial name
- NCT00068549
- Testing
- Gemcitabine Hydrochloride, Cisplatin, Radiation Therapy
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Gynecologic Oncology Group
Prostate Cancer
Radiation Therapy and Hormone Therapy in Treating Patients With Prostate Cancer
RATIONALE: Radiation therapy uses high energy x-rays to damage tumor cells. Hormone therapy combined with radiation therapy may be a more effective treatment for prostate cancer.
- Trial name
- NCT00769548
- Testing
- flutamide, goserelin acetate, low-LET photon therapy
- Volunteers
- 1,322 people
- Sponsor
- Radiation Therapy Oncology Group
Cervical Cancer
Radical Versus Simple Hysterectomy and Pelvic Node Dissection With Low-risk Early Stage Cervical Cancer
The reason this study is being done is to see if a simple hysterectomy is as good as a radical hysterectomy in preventing cancer of the cervix from returning, and whether, because less tissue surrounding the uterus is removed…
- Trial name
- SHAPE (NCT01658930)
- Testing
- Radical Hysterectomy + pelvic lymph node dissection, Simple hysterectomy + pelvic lymph node dissection
- Where
- 87 sites in Austria, Belgium and 9 more
- Volunteers
- 700 people
- Sponsor
- Canadian Cancer Trials Group
Prostate Cancer
Pelvic Health and Physical Therapy to Improve Lives of Prostate Cancer Patients Undergoing Prostatectomy
Patients will be randomized into standard of care or receiving pre and post operative physical therapy intervention following prostatectomy.
- Trial name
- NCT04027270
- Testing
- Physical Therapy
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Squamous Cell Carcinoma of Cervix
A Randomised Controlled Trial Between Two Different HDR Brachytherapy Schedule in Locally Advanced Carcinoma of Uterine Cervix
The purpose of this study is to compare two different brachytherapy treatment option in locally advanced carcinoma of uterine cervix.
- Trial name
- NCT02765919
- Testing
- HDR Brachytherapy of 9 Gy in 2 fractions, HDR Brachytherapy of 7 Gy in 3 fractions
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Abdominal Cancer
Tracked Ultrasound for Patient Registration in Surgical Navigation During Abdominal Cancer Surgery
The goal of this observational pilot study is to evaluate the feasibility and accuracy of tracked ultrasound registration on patients undergoing abdominal cancer navigation surgery.
- Trial name
- NCT05637359
- Testing
- Tracked ultrasound measurement
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- The Netherlands Cancer Institute
Uterine Cancer, Cervical Cancer
Intensity Modulated Radiotherapy (IMRT) for the Pelvis Post-Hysterectomy
The goal of this clinical research study is to use CT scans to find any changes in position of the vagina and pelvic lymph node areas during the course of IMRT radiation therapy.
- Conditions
- Uterine Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- NCT00508703
- Testing
- Intensity Modulated Radiotherapy (IMRT), CT Scan
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- M.D. Anderson Cancer Center
Cervical Cancer
A Study of Camrelizumab Combined With Concurrent Chemoradiation in Patients With Cervical Cancer
In this single-arm study, patient with cervical cancer who had recurrence of the pelvic wall after surgery ± Abdominal aortic lymph node metastasis will be included to evaluate the efficacy and safety of camrelizumab combined…
- Trial name
- NCT04974827
- Testing
- Camrelizumab, Cisplatin or Carboplatin
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Hunan Cancer Hospital
Efficacy of Adding Lidocaine 10% to Phenol in Superior Hypogastric Plexus Neurolysis
Efficacy of Adding Lidocaine 10% to Phenol in Ultrasound Guided Superior Hypogastric Plexus Neurolysis in The Management of Pelvic Cancer Pain
The superior hypogastric plexus (SHP) is a complex nervous collection located at the lumbosacral region below the level of the aortic bifurcation at the level of the lower third of the fifth lumbar vertebral body and upper third…
- Trial name
- NCT05145972
- Testing
- Ultrasound Guided Superior Hypogastric Plexus
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall, Infiltrating Renal Pelvis and Ureter Urothelial Carcinoma
Testing the Addition of an Anti-Cancer Immunotherapy Drug, Avelumab, to Gemcitabine and Carboplatin Chemotherapy Prior to Surgery in Muscle Invasive Urinary Tract Cancer vs. Surgery Alone in Patients Who Are Not Able to Receive Cisplatin Therapy (SWOG GAP TRIAL)
This phase II trial studies the effect of avelumab, gemcitabine and carboplatin before surgery compared with surgery alone in treating patients with muscle invasive bladder or upper urinary tract cancer who are not able to…
- Conditions
- Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall, Infiltrating Renal Pelvis and Ureter Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8
- Trial name
- NCT04871529
- Testing
- Therapeutic Conventional Surgery, Avelumab, Gemcitabine Hydrochloride
- Where
- 92 sites in United States
- Volunteers
- 6 people
- Sponsor
- SWOG Cancer Research Network
Pelvic Floor Disorders
Evaluation of the Subjectively Perceived Pelvic Floor Function in Patients With Gynecological Tumors and Breast Cancer Under Systemic Tumor Therapy Using a Validated Questionnaire
The multimodal therapy of gynecological malignancies and breast cancer often leads to an impairment of the pelvic floor function. This has a major impact on the quality of life of cancer patients.
- Trial name
- NCT04655066
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- St. Josefs-Hospital Wiesbaden GmbH
Cancer of Rectum, Lymph Node Disease
Fluorescence Targeted Pelvic Lymph Node Mapping
This study aims to assess the lymphatic drainage of rectal tumours by using ICG as a fluorescent non-specific marker. As a feasibility study, it will also assess its technique and timing along with its ability to assist in…
- Trial name
- NCT03204994
- Testing
- Indocyanine Green
- Where
- United Kingdom
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
BRCA1 Mutation, BRCA2 Mutation
Radical Fimbriectomy for Young BRCA Mutation Carriers
Some BRCA-mutated women are reluctant to undergo laparoscopic bilateral salpingo-oophorectomy. The goal of the bilateral laparoscopic radical fimbriectomy the investigators suggest, is to suppress the tubal source of possible…
- Conditions
- BRCA1 Mutation, BRCA2 Mutation, Hereditary Breast and Ovarian Cancer
- Trial name
- FIMBRIECTOMIE (NCT01608074)
- Testing
- Radical fimbriectomy, Histopathology SEE-FIM
- Where
- 14 sites in France
- Volunteers
- 123 people
- Sponsor
- Centre Oscar Lambret
Cervical Cancer, Lymphocyst
A Trial Comparing Observation With Radiation on Pelvic Lymphocysts After Radical Hysterectomy of Cervical Cancer
Cervical cancer of early stage is treated mainly by radical resection and (or) radiotherapy. And pelvic lymphocyst is one of the most common adverse events of radical resection.
- Conditions
- Cervical Cancer, Lymphocyst, Radiation Therapy
- Trial name
- NCT03071289
- Testing
- Radiation Method B, Cisplatin, Radiation Method A
- Where
- 8 sites in China
- Volunteers
- 540 people
- Sponsor
- Sun Yat-sen University