Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse (POP)
Efficacy and Safety of Laparoscopic Lateral Suspension and Transvaginal Sacrospinous Ligament Fixation in Patients With Pelvic Organ Prolapse
This study is a single-center, non-blinded, non-inferiority randomized controlled trial, planning to recruit 86 patients with Stage III or higher pelvic organ prolapse who are unresponsive to conservative treatment and are…
- Trial name
- NCT06903988
- Testing
- laparoscopic lateral suspension, Transvaginal sacrospinous ligament fixation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Peking University People's Hospital
Pelvic Organ Prolapse, Gynecologic Cancers
Electronic Catheter Stethoscope
This is an observational, exploratory study designed to collect (record) and analyze normal and abnormal sound data from the human bladder during surgery using a novel sensor-based catheter system (Electronic Catheter…
- Conditions
- Pelvic Organ Prolapse, Gynecologic Cancers, Uterine Leiomyomata, Adenomyosis
- Trial name
- NCT01463462
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of South Florida
Pelvic Organ Prolapse
Same Day Discharge After Minimally-invasive Sacrocolpopexy
This is a prospective cohort study evaluating safety, cost and patient satisfaction with SDD for patients undergoing minimally invasive sacrocolpopexy for pelvic organ prolapse.
- Trial name
- NCT03730103
- Testing
- Same day discharge
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse
Postoperative Opioid Consumption After Urogyneocologic Surgery
The purpose of this randomized controlled trial is to evaluate whether preoperative opioid education will reduce postoperative opioid consumption after urogynecologic surgeries.
- Trial name
- NCT03586219
- Testing
- Opioid-specific educational patient pamphlets
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- University of California, Irvine
Pelvic Organ Prolapse
EVeRLAST 2-Year Follow-Up
This is a 2-year follow-up study from EVeRLAST which objective was to determine whether expedited resumption of postoperative activity levels is non-inferior to standard activity restrictions with respect to short-term anatomic…
- Trial name
- NCT05542836
- Testing
- Expedited postoperative activity instructions, Standard postoperative activity restructions
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Duke University
Pelvic Organ Prolapse
Use of Pre-Emptive Pudendal Nerve Block for Pelvic Reconstructive Surgery
The purpose of this study is to determine the effectiveness of perineal pain control via injection of a local anesthetic to numb the pudendal nerve. The medication which is commonly used for this block is called marcaine.
- Trial name
- NCT02409498
- Testing
- pudendal block, no pudendal block
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pelvic Organ Prolapse
Prolapse and Pregnancy Assessment
Pelvic organ prolapse (POP) is one of the most common indications for gynaecological surgery. In 1997, more than 225000 inpatient surgical procedures for POP were undertaken in USA (22.7 per 10000 women) at an estimated cost of…
- Trial name
- PAPA (NCT01321762)
- Where
- United Kingdom
- Volunteers
- 403 people
- Sponsor
- Croydon University Hospital
Pelvic Organ Prolapse, Patient Preparedness
Patient Preparedness for Pelvic Organ Prolapse Surgery
Patient preparedness has been associated with increased patient satisfaction, decreased postoperative pain and decreased postoperative narcotic use; however, little is known regarding the optimal way to prepare patients prior to…
- Trial name
- PREOP (NCT03836365)
- Testing
- Preoperative counseling office visit, Preoperative counseling phone call
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Pittsburgh
Prolapse, Urinary Incontinence
Long-term Effectiveness of Abdominal Sacrocolpopexy for the Treatment of Pelvic Organ Prolapse
The Colpopexy and Urinary Reduction Effort (CARE) trial is a research study designed to evaluate whether the addition of a second surgical procedure in addition to a procedure for female pelvic organ prolapse (POP) affects the…
- Trial name
- E-CARE (NCT00099372)
- Where
- 8 sites in United States
- Volunteers
- 215 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Vaginal Vault Prolapse, Enterocele
Sacrocolpopexy Versus Vaginal Mesh Procedure for Pelvic Prolapse
Pelvic prolapse is one of the most frequent pathology in Gynecology. Recurrency of the prolapse after primary surgery is relatively high, 15-30%.
- Conditions
- Vaginal Vault Prolapse, Enterocele, Uterine Prolapse, Cystocele
- Trial name
- NCT01097200
- Testing
- Elevate mesh, Sacrocolpopexy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Francisco Carmona
Pelvic Organ Prolapse
Abdominal Sacral Hysteropexy Versus Vaginal Sacrospinous Hysteropexy
The aim of the current study is to compare abdominal sacral cervicopexy with vaginal sacrospinous cervicopexy in women with apical prolapse in terms of operative time, procedures safety and efficacy.
- Trial name
- NCT04850365
- Testing
- Hysteropexy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Prolapse
Use of Non-ablative Vaginal Erbium YAG Laser for the Treatment of Prolapse
This is a single center, investigator initiated study, sponsored by the UZ Leuven, Leuven, Belgium; comparing laser treatment to pelvic floor exercises (PFE).
- Trial name
- VELPOP (NCT04523298)
- Testing
- Non-ablative vaginal Erbium YAG laser treatment, Pelvic floor exercises (PFE)
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cystocele
Nerve Access Tool Study
The purpose of this study is to assess the ability of the nerve access tool to facilitate nerve stimulation lead placement.
- Trial name
- NCT00942474
- Testing
- Facilitate nerve stimulation lead placement with the nerve access tool
- Sponsor
- MedtronicNeuro
Pelvic Organ Prolapse Recurrence
The Efficacy of Laparoscopic Sacrocolpopexy in the Treatment of Pelvic Organ Prolapse in Women With or Without Avulsion of the Levator Ani Muscle
Based on a prospective study, to evaluate how pre-operative pelvic floor status - the presence of injury to the musculus levator ani - may influence the results of laparoscopic sacrocolpopexy.
- Trial name
- NCT03049020
- Testing
- laparoscopic sacrocolpopexy
- Where
- 2 sites in Czechia
- Volunteers
- 120 people
- Sponsor
- Charles University, Czech Republic
Pelvic Organ Prolapse, Urinary Incontinence
Intelligent Diagnosis and Treatment System for Pelvic Floor Dysfunction in Elderly Women
The aim of this study is to propose an intelligent diagnosis and treatment system for for pelvic floor dysfunction in elderly women.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Diagnosis
- Trial name
- NCT06372340
- Testing
- Personalized pelvic floor rehabilitation program generated by the intelligent diagnosis and treatment system., Standard pelvic floor muscle training(PFMT) program
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Cystocele, Pelvic Organ Prolapse
Safety and Efficacy of Non-ablative Er:YAG Laser Therapy for the Treatment of Pelvic Organ Prolapse and Coexisting Stress Urinary Incontinence: A Retrospective Case Series.
The objective of the study is to retrospectively collect the data on patients who underwent pelvic organ prolapse treatment using a non-ablative Er:YAG laser with SMOOTH mode and to conduct an objective evaluation of safety and…
- Conditions
- Cystocele, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- NCT04417413
- Testing
- Fotona ProlapLase
- Where
- Serbia
- Volunteers
- 41 people
- Sponsor
- Aleksandra Novakov Mikic
Pelvic Organ Prolapse
Feasibility Study of the Reia Vaginal Pessary
The purpose of this study is to obtain preliminary data on the effectiveness, safety, function, comfort, and patient satisfaction with a novel vaginal pessary design for the use in women who suffer from symptoms of pelvic organ…
- Trial name
- NCT04508335
- Testing
- Reia Vaginal Pessary
- Where
- 7 sites in United States
- Volunteers
- 78 people
- Sponsor
- Reia, LLC
Pelvic Organ Prolapse
Comparisons of Clinical Outcomes Between Novel Tailored Transvaginal Mesh Surgery and Vaginal Native Tissue Repair Surgery for Pelvic Organ Prolapse
The issue of whether utilizing the mesh in the surgical treatment of pelvic organ prolapse remained undetermined.Thus, the aim of this study is to analyze clinical outcome of women who underwent pelvic organ prolapse surgeries…
- Trial name
- NCT02465710
- Testing
- Pelvic organ prolapse surgery without mesh, Pelvic organ prolapse surgery with mesh
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University Hospital
Pelvic Floor Prolapse
Anterior Prolift Versus Posterior Prolift for Pelvic Floor Prolapse
Women who had surgery for pelvic floor prolapse underwent surgery by anterior Prolift or Posterior prolift at least a year after the surgery.
- Trial name
- NCT01392417
- Where
- 2 sites in Israel
- Volunteers
- 140 people
- Sponsor
- Western Galilee Hospital-Nahariya
Pelvic Organ Prolapse, Stress Urinary Incontinence
Lidocaine for Pessary Check Pain Reduction
The primary objective of this study is to estimate the effect of lidocaine jelly on patient pain at the time of office pessary removal.
- Trial name
- NCT05493735
- Testing
- Lidocaine Hcl 2% Jelly
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida