Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse
Robotic Assisted Sacral Colpopexy : A Prospective Study Assessing Outcomes With Learning Curves
The investigators scientific aims are to determine the benefits associated with the use of robotic assisted laparoscopic sacrocolpopexy surgery on women with prolapse, to define how the benefits impact the patient, physician and…
- Trial name
- NCT01535833
- Testing
- Device- Robotic sacral colpopexy
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Anterior Pelvic Organ Prolapse
Trial of Small Intestine Submucosa (SIS) Mesh for Anterior Repair: A Pilot Study
Prolapse occurs when pelvic organs drop down and cause a bulging of the tissues. An "anterior wall prolapse" occurs when the front of the vagina loses its support, and the bladder drops down and rotates into the vaginal opening.
- Trial name
- Anterior SIS (NCT00955448)
- Testing
- SIS mesh (Cook Medical), Anterior prolapse repair
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- University of Calgary
Pelvic Organ Prolapse
FINPOP 2015: Incidence, Methods, Complications and Quality of Life of Pelvic Organ Prolapse Operations in Finland 2015
The aim of this study is to investigate the safety and effectivity of pelvic organ prolapse (POP) surgery. In this multi center study the population consists of POP operations done in Finland year 2015.The study is prospective…
- Trial name
- NCT02716506
- Testing
- POP surgery
- Where
- Finland
- Volunteers
- 3,515 people, healthy volunteers welcome
- Sponsor
- Society for Gynecological Surgery in Finland
Uterine Prolapse, Vault Prolapse
Laparoscopic Sacral Colpopexy Versus Modified Total Pelvic Floor Reconstructive Surgery for Apical Prolapse Stage III-IV
Pelvic Organ prolapse (a feeling of bulge in the vagina) may cause some distressing symptoms such as loss of control of the bowel or bladder, and may also cause problems with patient's sex life. The primary treatment is surgery.
- Trial name
- NCT01762384
- Testing
- LSC, modified PFRS, "Gynemesh"
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Rectal Prolapse
Comparison of Cow Milk and 15% Hypertonic Saline in the Treatment of Rectal Prolapse in Children
To see the outcome of results of Cow Milk \& Hypertonic Saline in the treatment of Rectal Prolapse in Children
- Trial name
- NCT06174584
- Testing
- Hypertonic saline, Cow Milk
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Vaginal Prolapse
A Randomised, Controlled Study of Bimesh, Pelvicol for Vaginal Wall Prolapse
Anterior vaginal wall prolapse is a common problem. Until now many different surgical techniques have been evaluated but so far recurrence is often still observed.
- Trial name
- NCT00442247
- Testing
- Pelvicol
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Urinary Incontinence, Stress, Mixed Incontinence
Treatment for Stress and Mixed Urinary Incontinence and Vaginal Vault Prolapse
The primary objective of this study is to further evaluate the safety and effectiveness of the use of a sling device in women for stress and mixed urinary incontinence as well as vaginal vault prolapse.
- Conditions
- Urinary Incontinence, Stress, Mixed Incontinence, Vaginal Vault Prolapse
- Trial name
- NCT00223106
- Testing
- Vaginal Sling
- Where
- United States
- Volunteers
- 467 people
- Sponsor
- Medtronic - MITG
Pelvic Organ Prolapse, Urinary Incontinence
Pelvic Organ Prolapse Repair With or Without Concomitant Burch Colposuspension in Patients With Urinary Incontinence
To evaluate the impact of Burch colposuspension (BC), as an anti-incontinence measure, in patients with urinary incontinence (UI) undergoing abdominal surgery for pelvic organ prolapse (POP) repair
- Trial name
- NCT00576004
- Testing
- Pelvic organ prolapse repair and Burch colposuspension
- Where
- Italy
- Volunteers
- 67 people
- Sponsor
- University Of Perugia
Pelvic Organ Prolapse
Vaginal Vault Native Tissue Suspension
Vaginal vault suspension at time of abdominal hysterectomy using Mackenrodt and uterosacral ligaments.
- Trial name
- NCT07517965
- Testing
- Mackenrodt uterosacral double ligaments suspension
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Assiut University
Sexual Function
Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy
This is a single center, double-blind, randomized controlled trial evaluating the change in sexual function in women undergoing vaginal repair for pelvic organ prolapse.
- Trial name
- FaVR (NCT01779739)
- Testing
- Perineorrhaphy
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Pelvic Organ Prolapse
PEssary Plus Physiotherapy for Pelvic Organ Prolapse (PEPPY)
1. To determine the feasibility of conducting a randomised controlled trial (RCT) of the effectiveness of a PFMT intervention in conjunction with vaginal pessary management versus vaginal pessary management alone for women with…
- Trial name
- PEPPY (NCT01136889)
- Testing
- PFMT
- Where
- 4 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Glasgow Caledonian University
Obstructed Defecation, Pelvic Organ Prolapse
Prospective Randomized Controlled Trial of Obstructed Defecation Surgery
Obstructive defecatory syndrome (ODS) or inability to completely empty bowel is characterized by a combination of straining, incomplete evacuation, and the use of digital manipulation with bowel movement.
- Trial name
- PROD (NCT05747027)
- Testing
- Laparoscopic abdominal ventral rectopexy, Transvaginal sacrospinous rectopexy
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Endeavor Health
Colon Cleansing
Will Cleaning the Bowel With an Enema Before Vaginal Prolapse Surgery Prevent Complications?
Traditionally, many gynecologic surgeons have asked patients to perform a cleansing enema the night before a vaginal surgery done to repair pelvic organ prolapse (dropped bladder, dropped uterus).
- Trial name
- NCT00981539
- Testing
- enema
- Where
- 2 sites in United States
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Illinois Urogynecology, Ltd.
Prolapse, Vaginal, Paravaginal Cystocele
Short-term Outcomes of Laparoscopic Repair of Paravaginal Defects
this study designed To evaluate the efficacy and outcomes of laparoscopic approach for repair of paravaginal defects associated with anterior vaginal wall prolapse.
- Trial name
- NCT03962075
- Testing
- laparoscopic paravaginal repair
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Pelvic Organ Prolapse
RCT for Transvaginal Self-cut Mesh vs Mesh-kit for Severe POP
Pelvic organ prolapse(POP) is a common health problem and has significant negative effects on woman's quality of life. Transvaginal mesh procedure is a durable reconstructive surgery, but the mesh kits are expensive for…
- Trial name
- NCT03849157
- Testing
- pelvic floor reconstructive surgery
- Where
- 11 sites in China
- Volunteers
- 312 people
- Sponsor
- Peking Union Medical College Hospital
Pelvic Organ Prolapse, Pelvic Floor Prolapse
Laparoscopic Lateral Suspension With Mesh & Sacrocervicopexy for the Treatment of Uterine Prolapse
This study is aimed to compare the efficiency of two uterus-preserving laparoscopic methods to treat uterine prolapse in a randomized controlled trial.
- Trial name
- NCT03421457
- Testing
- Uterus-preserving laparoscopic lateral suspension with mesh, Uterus-preserving laparoscopic sacrocervicopexy with mesh
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Obstructive Defecation Syndrome, Chronic Constipation
Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructed Defecation Syndrome
Obstructed defecation syndrome (ODS) is a common problem in women. Rectal prolapse and rectocoele are frequently identified in patients with ODS.
- Conditions
- Obstructive Defecation Syndrome, Chronic Constipation, Rectal Prolapse
- Trial name
- NCT03060330
- Testing
- Modified Laparoscopic Ventral Mesh Rectopexy, Modified Laparoscopic Ventral Mesh Rectopexy Combined with Stapled Trans-anal Rectal Resection
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Renmin Hospital of Wuhan University
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery
Suzetrigine is a selective NaV1.8 inhibitor that provides peripheral analgesia without opioid-related CNS effects. This single-center stepped-wedge randomized clinical trial evaluates whether a suzetrigine-based postoperative…
- Conditions
- Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
- Trial name
- NCT07600697
- Testing
- Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Pelvic Organ Prolapse
Timing of Pessary Care
This is a prospective trial to investigate optimal timing of care for vaginal pessaries. A vaginal pessary is a silicone device that is placed in the vagina to support the pelvic organs of a woman who has pelvic organ prolapse.
- Trial name
- NCT02371083
- Testing
- Extended timing of pessary care
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Hartford Hospital
Voiding Dysfunction After Pelvic Organ Prolapse Surgery
Post-operative Voiding Dysfunction: the Preferred Method for Catheterization
This study is divided into two parts. The first part is a prospective observational study of patients undergoing pelvic organ prolapse (POP) surgery.
- Trial name
- NCT01597544
- Testing
- CISC instruction pre-operatively
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Unity Health Toronto