Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse, Quality of Life
Quality of Life After Conservative and Surgical Treatment of Pelvic Organ Prolapse
This is an observational study that gives baseline and follow-up information, that does not directly influence the allocation of patients to various treatment Options (conservative and surgical therapy of Pelvic Organ Prolapse)…
- Conditions
- Pelvic Organ Prolapse, Quality of Life, Incontinence
- Trial name
- LOLIPOP (NCT04110821)
- Where
- Switzerland
- Volunteers
- 134 people
- Sponsor
- University Hospital, Basel, Switzerland
Cystocele, Uterine Prolapse
Anterior Pelvic Prolapse Reconstruction With TiLOOP® PRO A Polypropylene Mesh
The purpose of this study is to determine the influence of anterior pelvic prolapse reconstruction with a titanized polypropylene mesh on patients quality of life.
- Trial name
- NCT02690220
- Testing
- TiLOOP® PRO Plus A
- Where
- 5 sites in Germany
- Volunteers
- 54 people
- Sponsor
- pfm medical gmbh
Rectal Prolapse, Procidentia
An International Double Cohort Study to Compare Laparoscopic Ventral Rectopexy With Laparoscopic Resection Rectopexy
Background: Rectal prolapse (RP) is the descent of the upper rectum and is a common problem in the western world. Surgery is the only definite treatment and is preferably performed minimally invasive.
- Trial name
- LaProS (NCT01595412)
- Testing
- Laparoscopic Resection Rectopexy, Laparoscopic Ventral Rectopexy
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse
Superiority of Perineoplasty as Concomitant Surgical Procedure During Pelvic Organ Prolapse Repair
The goal of this study is to evaluate whether adding perineoplasty is, in comparison to performing vaginal prolapse surgery without adding perineoplasty, superior with respect to efficacy and cost-effectiveness and non-inferior…
- Trial name
- SUPPORT (NCT05713422)
- Where
- 2 sites in Netherlands
- Volunteers
- 305 people
- Sponsor
- Marjolein Spiering
Pelvic Organ Prolapse
Veritas Collagen Matrix Cystocele Repair Study - Postmarketing
The purpose of this study is to evaluate the Veritas Collagen Matrix in treating female patients with documented occurence of Pelvic Organ Prolapse as evidenced by a cystocele.
- Trial name
- NCT00860912
- Testing
- Collagen Matrix
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse
Unilateral Versus Bilateral High Uterosacral Ligament Suspension Following vNOTES Hysterectomy for Apical Pelvic Organ Prolapse: A Prospective Study
This study aims to compare unilateral and bilateral high uterosacral ligament suspension techniques performed following vaginal hysterectomy in patients with pelvic organ prolapse.
- Trial name
- HUSLS (NCT07552337)
- Testing
- High Uterosacral Ligament Suspension
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Post Operative Pain Control, Narcotic Use
Sprix for Postoperative Pain Control Following Gynecologic Surgery
The ongoing opioid epidemic has altered both how physicians prescribe narcotics and patients' perceptions of those prescriptions.
- Conditions
- Post Operative Pain Control, Narcotic Use, Pelvic Organ Prolapse, Urinary Incontinence , Stress
- Trial name
- NCT04444830
- Testing
- Sprix
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Sexual Function Disturbances, Pelvic Organ Prolapse
Pelvic Floor Disorders Among Sexual Minoritized Women
The investigators aim to perform cognitive interviews to assess how pelvic floor disorders impact sexual functioning in women who have sex with women (WSW).
- Conditions
- Sexual Function Disturbances, Pelvic Organ Prolapse, Urinary Incontinence, Fecal Incontinence
- Trial name
- PRIDE (NCT05072158)
- Testing
- None, this is an observational study
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of New Mexico
Anesthesia, Local, Prolapse
Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy
The purpose of this study is to assess whether the transversus abdominis plane block (Tap block) is different than the oral postoperative pain medications in controlling pain after robotic sacrocolpopexy.
- Conditions
- Anesthesia, Local, Prolapse, Prolapse; Female, Prolapse, Vaginal
- Trial name
- SACROTAP (NCT04440475)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- ProMedica Health System
Vaginal Prolapse
The Use of Avaulta for Anterior Repair
Summary: Vaginal prolapse is a well-known disease and is observed in approximately 11% of all postmenopausal women and tending to increase with age.
- Trial name
- NCT00918099
- Testing
- Avaulta mesh, Anterior repair
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Zealand University Hospital
Pelvic Organ Prolapse
Uterosacral Ligament Suspension Clip
This study seeks to gain a more thorough understanding of the postoperative location of the sutures placed during uterosacral ligament suspension.
- Trial name
- USLS (NCT02700997)
- Testing
- Vascular Clip
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- TriHealth Inc.
Vaginal Prolapse, Uterine Prolapse
Efficacy Study of Vaginal Mesh for Anterior Prolapse
The primary aim of this double-blind, randomized clinical trial (RCT) is to test the hypothesis that the addition of a standardized technique of interpositional synthetic polypropylene mesh placement improves the one-year outcome…
- Conditions
- Vaginal Prolapse, Uterine Prolapse, Cystocele, Pelvic Organ Prolapse
- Trial name
- VAMP-A (NCT00557882)
- Testing
- synthetic polypropylene mesh
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Medstar Health Research Institute
Pelvic Organ Prolapse Vaginal Surgery, Platelet Rich Plasma Injection
The Effects of Platelet Rich Plasma Adjuvant to Type I/III Collagen Ratio, Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Pelvic Organ Prolapse Repair
The goal of this clinical trial is to analyze the effect of Platelet Rich Plasma (PRP) Adjuvant To Type I/III Colagen Ratio, MMP-2 and MMP-9 in Pelvic Organ Prolapse Repair.
- Trial name
- POP PRP MMP (NCT07150442)
- Testing
- POP surgery and PRP injection
- Where
- Indonesia
- Volunteers
- 34 people
- Sponsor
- Andalas University
Pelvic Organ Prolapse, Urinary Incontinence
Pelvic Floor Muscle Training Programme in Pregnant Nepalese Women- a Feasibility Study
To our knowledge, no studies in Nepal have reported the feasibility of performing the pelvic floor muscle training in Nepalese women.
- Trial name
- PFMT (NCT03349736)
- Testing
- Pelvic Floor Muscle Training
- Where
- Nepal
- Volunteers
- 253 people
- Sponsor
- Kathmandu University School of Medical Sciences
Pelvic Prolapse Conditions
Barriers and Enablers to Accessing Medical Care for Urinary Incontinence and Prolapse in GLobal Majority Women
This project aims to explore barriers to treatment seeking for symptoms of prolapse and urinary incontinence in women from ethnic minority/global majority background.
- Trial name
- BEAM UP & GLOW (NCT07310121)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Prolapse, Vaginal Vault
Transvaginal Mesh vs. Laparoscopic Colposacropexy- Study
The main objective of the study is to compare subjective efficacy of trans vaginal mesh and laparoscopic colposakropexy (CSP) in women with an apical prolapse.
- Trial name
- TVM vs LCSP (NCT04478747)
- Testing
- TVM, Colposacropexy
- Where
- Finland
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Pelvic Organ Prolapse, Perioperative/Postoperative Complications
Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery
This study will recruit women scheduled to undergo vaginal apical suspension surgery (either uterosacral ligament suspension or sacrospinous ligament fixation) with or without other prolapse or anti-incontinence procedures.
- Trial name
- NCT05658887
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Joseph Kowalski
Pelvic Floor Dysfunctions
Central Sensitization Inventory and Symptoms of Pelvic Floor Dysfunctions
The goal of this observational study is to assess the values of Central Sensitization Inventory in women in a gynecology outpatient clinic.
- Trial name
- NCT07154576
- Where
- Poland
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Pelvic Organ Prolapse
Gabapentin Reduces Opioid Use Postoperatively ("GROUP Study")
Gabapentin is a medication used primarily to treat seizures and pain. Studies have shown that this medication can help reduce pain after surgery, including hysterectomy, where the uterus or "womb" is removed.
- Trial name
- GROUP (NCT02999724)
- Testing
- Gabapentin
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Mount Sinai Hospital, Canada
Pelvic Organ Prolapse, Surgery
Predictors of Recovery Expectancy
The purpose of this study is to identify factors that influence a person's expectations regarding recovery from pelvic organ prolapse surgery.
- Trial name
- NCT04274491
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Indiana University