Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse
A Large Multi-Center Database of Women Who Have Had and Are Going to Have Surgical Correction of Their Pelvic Organ Prolapse Using the Gynecare Prolift System
retrospective and prospective data collection for a database. Patients will have had or are going to have a repair of their pelvic organ prolapse using the Gynecare mesh Prolift System
- Trial name
- NCT01134003
- Where
- United States
- Sponsor
- The Institute of Pelvic Medicine & Reconstructive Surgery, Allentown, Pennsylvania
Quality of Life, Urinary Incontinence
The Pelvic Floor Function and Sexual Life of the Women After Different Type of Hysterectomy
In this prospective, comparative non-randomized multiple teaching hospitals study, the investigators try to determine the relationship of total hysterectomy and Taiwanese female pelvic floor and sexual function from the view of…
- Conditions
- Quality of Life, Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- HYS-PF-QOL (NCT02841059)
- Testing
- LSH, CLSH, LAVH
- Where
- 4 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Pelvic Organ Prolapse, Postoperative Pain Management
SORE Study: Sitz Baths After Urogynecologic Reconstruction
The purpose of this study is to evaluate the utility of postoperative sitz baths in patient pain perception and recovery following surgical repair of prolapse.
- Conditions
- Pelvic Organ Prolapse, Postoperative Pain Management, Gynecologic Surgeries
- Trial name
- SORE (NCT07215780)
- Testing
- Sitz Bath
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Yale University
Pelvic Organ Prolapse
Guided IMagery and Patient Satisfaction (GIMPS) Following Urogynecological Surgery
We hypothesize that women who use GIM pre-operatively will feel more prepared for surgery, have less anxiety on the day of surgery and have higher satisfaction scores 6 weeks after surgery compared to women who undergo our…
- Trial name
- GIMPS (NCT02165280)
- Testing
- Guided IMagery (GIM)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Loyola University
Pelvic Organ Prolapse
Ischia Spinous Fascia Fixation Procedure Versus Modified Total Pelvic Floor Reconstructive Surgery for Pelvic Organ Prolapse Stage III
Pelvic organ prolapse is a common problem. The primary treatment is surgery. Ischia spinous fascia fixation procedure and modified total pelvic floor reconstructive surgery with mesh are both developed in China for vaginal apex…
- Trial name
- NCT01670682
- Testing
- ischia spinous fascia fixation, Modified Pelvic Floor Reconstruction Surgery with Mesh, polypropylene mesh(Gynemesh)
- Where
- 5 sites in China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
Pelvic Floor Prolapse, Surgery
The Effect of Preemptive Levator Ani Injections on Pain After Pelvic Reconstructive Surgery
Patients undergoing vaginal pelvic reconstructive surgery for pelvic organ prolapse (POP) under general anesthesia will be randomized to receive bilateral trans-vaginal pelvic floor muscle injections with bupivacaine or no…
- Conditions
- Pelvic Floor Prolapse, Surgery, Pain, Postoperative
- Trial name
- NCT04428320
- Testing
- Pelvic floor injection
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- The Cooper Health System
Surgery, Knowledge, Attitudes, Practice
What is the Impact of the Presence of a Support Person on Informed Consent
In practice, the Investigators recommend that patients bring a family member or close friend to their pre-operative appointment to help with patient anxiety, comprehension, and informed decision-making.
- Conditions
- Surgery, Knowledge, Attitudes, Practice, Prolapse, Vaginal, Urinary Incontinence
- Trial name
- NCT03966469
- Testing
- Preoperative support person present, Patient Present Only
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Hartford Hospital
Pelvic Organ Prolapse, Stage II-III
Clinical Performance of GYNECARE PROSIMA* Pelvic Floor Repair System for Symptomatic Pelvic Organ Prolapse
The purpose of this study is to evaluate the safety and effectiveness of the GYNECARE PROSIMA* Pelvic Floor Repair System as a Device in Women with Symptomatic Pelvic Organ Prolapse.
- Trial name
- NCT01396122
- Testing
- Procedure: GYNECARE PROSIMA* Pelvic Floor Repair System
- Where
- 25 sites in China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Hysterectomy
Long-term Outcomes After Laparoscopic Subtotal and Total Hysterectomy
Hysterectomy is one of the most commonly performed gynecologic surgeries in the USA. It is used for many benign conditions such as leiomyoma and abnormal uterine bleeding.
- Trial name
- LAST-1 (NCT05421156)
- Testing
- Subtotal Laparoscopic Hysterectomy, Total Laparoscopic Hysterectomy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Uterine Prolapse
Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse
The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term…
- Trial name
- PREMIER (NCT05063331)
- Testing
- Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP), Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- University Hospitals Cleveland Medical Center
Rectocele, Pelvic Organ Prolapse
Fat Injection for Rectocele Treatment: A Novel Approach
This clinical trial aims to evaluate the effectiveness of autologous fat grafting as a novel treatment for rectocele, a condition characterized by the herniation of rectal tissue into the posterior vaginal wall.
- Conditions
- Rectocele, Pelvic Organ Prolapse, Obstructive Defecation Syndrome
- Trial name
- NCT06604702
- Testing
- Autologous Fat Injection for Rectocele
- Volunteers
- 25 people
- Sponsor
- Cairo University
Vaginal Prolapse
Local Infiltration Analgesia With Ropivacaine in Posterior Vaginal Wall Prolapse:a Randomized, Double-Blind Study
The purpose of this study is to compare systematic local infiltration with ropivacaine or placebo in patients undergoing repair of posterior vaginal wall prolapse.
- Trial name
- NCT00769054
- Testing
- Ropivacaine, Isotonic NaCl
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Pelvic Organ Prolapse
Comparison of Vaginal Axis on MRI in Alternative Apical Prolapse Surgeries to Sacrocolpopexy
Sacrocolpopexy remains the preeminent modality in addressing apical prolapse surgically. Nevertheless, amplified morbidity rates within cohorts characterized by obesity and advanced age constrain the advantages conferred by the…
- Trial name
- NCT06072456
- Testing
- laparoscopic lateral suspension, laparoscopic pectopexy, Sacrospinous ligament fixation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pelvic Organ Prolapse
Randomized,Multicentric Study to Treat Prolapse After Hysterectomy With Amreich Procedure or Total Prolift Procedure
Head to Head comparison of perioperative complications and secondary the impact of operation techniques with or without mesh on patients suffering from pelvic organ prolapse on quality of life.
- Trial name
- NCT00572702
- Testing
- Vaginal fixation Amreich-Richter, Prolift total
- Where
- 5 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- Charles University, Czech Republic
Pelvic Organ Prolapse
A Surgical Simulation Study to Evaluate the Safety of a Device Mechanism as Treatment for Vaginal Apical Prolapse
The purpose of this pilot study is to perform a procedure to evaluate the safety of the placement of a new device (known as the VFIX device).
- Trial name
- NCT00965952
- Where
- 4 sites in Australia
- Volunteers
- 49 people
- Sponsor
- Ethicon, Inc.
Pelvic Organ Prolapse
Pudendal Nerve Block for Postoperative Posterior Repair Pain Relief
Rectocoele or a posterior vaginal prolapse (bulge in the vagina) is a frequent gynaecological condition. It is repaired by repairing and reinforcing the support to the vaginal wall at the back.
- Trial name
- PPPR (NCT02502591)
- Testing
- Pudendal Nerve Block
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Pelvic Organ Prolapse
Interactive Web-Based Tool for Pelvic Organ Prolapse: Impact on Patient Understanding and Provider Counseling
The primary aim is to assess whether an interactive patient/provider counseling process using a web-based tool (iPadTM) will improve patient satisfaction regarding understanding of her bulge symptoms.
- Trial name
- iPad (NCT01864408)
- Testing
- "Usual practice" counseling, Standard "usual practice" clinical counseling with the pelvic organ prolapse web-based tool (iPad).
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Prolapse, Vaginal
Transperineal Ultrasound Evaluation of Vesicourethral Angle and de Novo SUI After Colpocleisis Surgery
This prospective observational study aims to evaluate changes in the vesicourethral angle using transperineal ultrasound before and after colpocleisis surgery, and to assess the relationship of these changes with the development…
- Trial name
- colpocleisis (NCT07071818)
- Testing
- Colpocleisis Group
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pelvic Organ Prolapse
Evaluation of the Results of Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh in the Surgical Treatment of Pelvic Organ Prolapse
Evaluation of the anatomical and functional results of laparoscopic sacrohysteropexy and sacrocolpopexy surgeries performed without using mesh in the surgical treatment of pelvic organ prolapse
- Trial name
- NCT06176521
- Testing
- Laparoscopic Sacrohysteropexy and Sacrocolpopexy Surgeries Performed Without Mesh
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Anterior Vaginal Wall Prolapse, Vaginal Apex/Uterine Prolapse
Demonstrate the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
A prospective, single arm, pre-market, multi-center clinical study to evaluate the safety and performance of the SRS (Lyra Medical) vaginal mesh in POP patients
- Trial name
- NCT02209337
- Testing
- SRS
- Where
- 3 sites in Hungary, Israel
- Volunteers
- 20 people
- Sponsor
- Lyra Medical Ltd.