Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP)
Accelerometer Measured Early Recovery After Prolapse Surgery
The AccelERate study will evaluate the physical recovery of patients who have undergone Pelvic Organ Prolapse (POP) surgery. This will be evaluated via a self-reported recovery questionnaire completed daily.
- Conditions
- Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Patient Education
- Trial name
- AccelERate (NCT07218016)
- Testing
- Postoperative Exercise regimen
- Where
- 7 sites in United States
- Volunteers
- 288 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Pelvic Organ Prolapse
Restorelle® Mesh Versus Native Tissue Repair for Prolapse
The purpose of this study is to collect information on the safety and effectiveness of Restorelle Direct Fix mesh and the surgical procedure to implant Restorelle.
- Trial name
- NCT02162615
- Testing
- Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior
- Where
- 49 sites in United States, Australia and 4 more
- Volunteers
- 810 people
- Sponsor
- Coloplast A/S
Nerve Block, Pain, Postoperative
Pudendal Nerve Block in Vaginal Surgery
The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared…
- Conditions
- Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse
- Trial name
- NCT04198714
- Testing
- Pudendal block
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Female Urinary Incontinence and Pelvic Organ Prolapse
Biomolecular Messages Associated With the Differentiation of Human Induced Pluripotent Stem Cells to Skeletal Muscle Progenitor Cells
Female urinary incontinence and pelvic organ prolapse are common diseases especially in aged women that frequently cause urogenital infection, voiding difficulty, urinary retention, pelvic pain, constipation, and coital…
- Trial name
- NCT02836145
- Testing
- Differentiation of hiPSCs to skeletal muscle progenitors
- Volunteers
- 6 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse, Posterior Vaginal Wall Defects
Traditional vs. Graft-augmented Posterior Colporrhaphy
Women who undergo posterior colporrhaphy with graft augmentation will have a lower recurrence of their posterior wall defect than women who undergo a traditional posterior colporrhaphy.
- Trial name
- NCT00581594
- Testing
- Graft-augmented colporrhaphy, Traditional posterior colporrhaphy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Irvine
Intestinal Obstruction, Pelvic Organ Prolapse
Biological Mesh Versus Synthetic Mesh in Interdisciplinary RRP With SCP
The purpose of the pilot study is to demonstrate the safety and efficacy of a biological mesh compared to a standard synthetic mesh for the planned procedure in the above-mentioned clinical picture.
- Conditions
- Intestinal Obstruction, Pelvic Organ Prolapse, Rectal Prolapse
- Trial name
- BioSynIRS (NCT06245577)
- Testing
- Laparoscopic mesh sacropexy (vagina, cervix) combined with resection rectopexy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Evangelisches Klinikum Köln Weyertal gGmbH
Vaginal Vault Prolapse
Study of Cytrix Use in Pelvic Floor Prolapse Treatment
To evaluate safety and effectiveness of using the fetal bovine dermis (Cytrix) in the treatment of pelvic organ prolapse.
- Trial name
- NCT01244165
- Testing
- Cytrix, Other treatments for pelvic organ prolapse
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Pelvic Floor Disorders
Correlation of Anal Acoustic Reflectometry Parameters With Degree of Rectal Intussusception and Prolapse
Anal Acoustic Reflectometry (AAR) is a reliable and reproducible technique that has been studied in our department over the last 6 years.
- Trial name
- NCT02774798
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Manchester University NHS Foundation Trust
Pelvic Organ Prolapse
Physical Therapy Intervention for Pelvic Organ Prolapses
Pelvic floor muscle training (PFMT) and pessaries are first-line non-surgical conservative treatments for pelvic organ prolapse (POP).
- Trial name
- NCT06532292
- Testing
- Biofeedback, HIFEM
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse
SIS Graft and Traditional Repair in Vaginal Wall Prolapse
The objective of this study is to evaluate surgical treatment of anterior vaginal wall prolapse using the sis graft or traditional repair. This a randomized and prospective study.
- Trial name
- NCT00827528
- Testing
- Traditional correction of anterior vaginal wall prolapse, Biologic Graft (SIS)
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Federal University of São Paulo
Rectal Prolapse, Rectocele
Long Term Results of STARR With Contour Transtar
Obstructed defecation syndrome (ODS) is a widespread and disabling syndrome. With this study the investigators want to evaluate the long term results of Stapled Transanal Rectal Resection (STARR) performed with Contour Transtar…
- Conditions
- Rectal Prolapse, Rectocele, Intussusception of Rectum
- Trial name
- LTSTARR (NCT02971332)
- Testing
- Stapled Transanal Rectal Resection
- Volunteers
- 113 people
- Sponsor
- University of Roma La Sapienza
Urinary Incontinence
Effect of Glutamine on Urinary Incontinence
The objective of this study is to determine to effect of additional oral glutamine to Kegel exercises on pelvic floor strength and clinical parameters of urinary incontinence in females with either urinary incontinence (stress…
- Trial name
- NCT03265509
- Testing
- glutamine supplementation, fantomalt supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Pelvic Organ Prolapse
A Multi-center Registry Study: The Follow-up the Complications for Trans-vaginal Mesh Surgery
This is a multi-center, prospective, observational, hospital-based registry of pelvic organ prolapse(POP) patients who having trans-vaginal mesh implantation with 12 month and 36 month follow-up.To investigate the incidence of…
- Trial name
- NCT04025047
- Where
- China
- Volunteers
- 4,147 people
- Sponsor
- Peking Union Medical College Hospital
Urinary Retention, Pelvic Organ Prolapse
Urinary Retention After Removing Urinary Catheter at 24 Hour Versus 48 Hour in Patients With Vaginal Surgery
Comparison incident of urinary retention in patients with vaginal surgery of pelvic organ prolapse, who removed urinary catheter at 24 hours versus 48 hours after surgery
- Trial name
- NCT04954443
- Testing
- Removing urinary catheter
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Pelvic Organ Prolapse
Uphold LITE Post-Market Surveillance Study
The purpose of this study is to compare transvaginal mesh repair to traditional native tissue repair in women surgically treated for anterior and/or apical pelvic organ prolapse.
- Trial name
- Uphold LITE (NCT01917968)
- Testing
- Uphold Lightweight Vaginal Support System, Traditional native tissue repair
- Where
- 28 sites in United States
- Volunteers
- 289 people
- Sponsor
- Boston Scientific Corporation
Rectal Prolapse, Defecation Disorder
Rectal Prolapse With ODS. STARR vs LVR.
The objective of the study will be to evaluate the clinical and functional outcome of patients with obstructed defecation sndrome (ODS) associated to internal rectal prolapse, treated with transanal prolassectomy (STARR) surgery…
- Conditions
- Rectal Prolapse, Defecation Disorder, Rectocele; Female, Surgery
- Trial name
- NCT04892108
- Testing
- STARR (Stapled Trans Anal Rectal Resection), LVR (Laparoscopic Ventral Rectopexy)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University Hospital of Ferrara
Pelvic Organ Prolapse
Evaluation of the Avaulta Procedure for the Correction of Pelvic Organ Prolapse - Results at 1 Year
This study is a 1 year review of all patients who had surgery to correct pelvic organ prolapse (i.e. cystocele, rectocele, enterocele) using the Avaulta synthetic mesh kit.
- Trial name
- NCT00774215
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse
Effects of a Follow-up Based Nursing Care Protocol on Pelvic Organ Prolapse
The goal of this clinical trial is to evaluate the effects of a follow-up-based nursing care protocol-implemented during the perioperative and post-discharge home care processes-on pelvic organ prolapse symptoms, quality of life…
- Trial name
- NCT06631508
- Testing
- Follow-up-based Nursing Care Protocol, Control Group: Routin Care
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Urinary Retention, Urinary Incontinence
Reducing Postoperative Catheterization
After reconstructive pelvic surgery urinary retention occurs in up to 60% of patients requiring an indwelling catheter or self-catheterization (1-5).
- Conditions
- Urinary Retention, Urinary Incontinence, Pelvic Organ Prolapse, Urinary Tract Infections
- Trial name
- NCT03009968
- Testing
- Post-void residual free voiding trial
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pelvic Organ Prolapse, PONV
Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP
The investigators hypothesize that preoperative administration of 8 mg IV dexamethasone will benefit patients' perceived quality of recovery after surgery.
- Trial name
- NCT02073734
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- TriHealth Inc.