Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse, Posterior Vaginal Wall Prolapse
Laparoscopic Fascial Duplication Plus Sacral Colpopexy in Posterior Vaginal Prolapse
A Randomized Clinical Trial on Laparoscopic Fascial posterior vaginal duplication with absorbable sutures plus sacral colpopexy mesh placement VS sacral colpopexy isolated for vaginal posterior prolapse
- Trial name
- NCT05252637
- Testing
- Laparoscopic Fascial Posterior Vagina Duplication
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico
Urinary Incontinence, Overactive Bladder
Pain-perception During Outpatient cystoscopy-a Prospective Controlled Study
At an academic tertiary referral center, patients with pelvic floor dysfunction, scheduled for outpatient cystoscopy or urodynamic testing will be asked to participate in the study.
- Conditions
- Urinary Incontinence, Overactive Bladder, Pelvic Organ Prolapse, Recurrent Urinary Tract Infections
- Trial name
- NCT01663181
- Where
- Austria
- Volunteers
- 109 people
- Sponsor
- Medical University of Vienna
Urinary Incontinence, Pelvic Organ Prolapse
Evaluation of the Benefits of Enhanced Recovery After Surgery (ERAS) Protocol in Pelvic Prolapse
ERAS protocols have been shown to improve recovery in terms of reduced pain, shortened time to ambulation and length of hospital stay.
- Trial name
- NCT04008654
- Testing
- ERAS Protocol, Conventional care
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pelvic Organ Prolapse (POP), Genital Prolapse
Safety and Performance of a Pelvic Floor Mesh Implant (LatGYNious)
The purpose of the clinical investigation is to verify that the investigational device (LatGYNious) is appropriate to significantly improve the pelvic organ prolapse in patients.
- Conditions
- Pelvic Organ Prolapse (POP), Genital Prolapse, Uterus Prolapse, Laparoscopic Surgery
- Trial name
- NCT07066761
- Testing
- Laparoscopic lateral suspension with surgical mesh (LatGYNious)
- Where
- 5 sites in Austria, Germany
- Volunteers
- 85 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Urogenital Prolapse
Is Preoperative Urodynamics Essential for Women With Pelvic Organ Prolapse
urodynamic investigation when added in the diagnostic work-up of women with lower urinary tract dysfunction with POP is debatable.
- Trial name
- urodynaemics (NCT04980196)
- Testing
- urodynaemic studies
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Pelvic Organ Prolapse, Abnormal Uterine Bleeding
Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery
This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Mesh Augmentation, Laparoscopic Surgery
- Trial name
- MIGS-ART (NCT06050161)
- Testing
- Articulating laparoscopic instrument, Conventional laparoscopic instrument, Robotic surgical instrument
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kern Medical Center
Uterine Prolapse, Cystocele
Prophylactic Antibiotic Treatment During Vaginal Repair
Prolapse of the uterus, bladder and rectum is a common condition in multiparous and/or elderly women. The number of operations for vaginal repair is increasing in Denmark, but there is no consensus or evidence found about the…
- Conditions
- Uterine Prolapse, Cystocele, Rectocele, Enterocele
- Trial name
- NCT00162604
- Testing
- Cefuroxime
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Hvidovre University Hospital
Pelvic Organ Prolapse
Outcomes and Patient Satisfaction After Colpocleisis for Pelvic Organ Prolapse
The purpose of this study is to evaluate the long-term success rate of the colpocleisis procedure and its effect on quality of life in women who have this surgery.
- Trial name
- NCT00714155
- Testing
- Questionnaires, Physical Examination
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Pelvic Organ Prolapse
Predictors of Post Operative Morbidity in Older Women With Pelvic Organ Prolapse
The Investigators hypothesize that functional status scores in elderly women undergoing surgery for pelvic organ prolapse will be lower at 6 weeks post-operatively but will have returned to baseline at 12 weeks post-operatively.
- Trial name
- NCT01967446
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Quality of Recovery, Same Day Surgery
Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?
To the investigators knowledge there are no studies in the literature evaluating the effect of Dexamethasone administration on patients undergoing outpatient vaginal prolapse surgeries.
- Conditions
- Quality of Recovery, Same Day Surgery, Nausea and Vomiting, Postoperative, Vaginal Prolapse
- Trial name
- NCT03338400
- Testing
- Dexamethasone, Normal saline
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- The Cleveland Clinic
Uterine Prolapse
Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy
This research protocol is a randomized controlled trial. It is being done to compare and find out the relative differences between the materials, (Pelivisoft) "natural organic mesh" to poly propylene mesh (Pelvitex) "manmade…
- Trial name
- NCT00564083
- Testing
- sacral colpopexy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Vaginal Vault Prolapse, Pelvic Floor Prolapse
Vaginal Vault Prolapse Surgical Treatment
Since apical support is the mainstay of vaginal cuff restoration, sacrocolpopexy is still accepted as the gold standard technique in vaginal vault prolapse (VVP).
- Trial name
- VVPST (NCT06792331)
- Testing
- vNOTES high uterosacral ligament suspension, Laparoscopic lateral suspension
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Pelvic Organ Prolapse
Apical Support During Hysterectomy for Pelvic Organ Prolapse
This is a retrospective chart review using TriHealth Electronic Privacy Identification Center (EPIC) to determine whether gynecologic surgeons at a large community hospital are already meeting the recently recommended best…
- Trial name
- NCT03379246
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse, Uterine Prolapse
Does a High BMI Affect Supervised Pelvic Floor Muscle Training for Improving Symptoms in Women With Various Stages of Pelvic Organ Prolapse?
The trial design is a quasi-experimental cohort trial that includes women referred for pelvic organ prolapse specific physiotherapy.
- Conditions
- Pelvic Organ Prolapse, Uterine Prolapse, Anterior Wall; Prolapse, Vaginal, Posterior Wall; Prolapse, Vaginal
- Trial name
- NCT04009694
- Testing
- Pelvic Floor Muscle training
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salford
Pelvic Organ Prolapse
Prospective Long-term Evaluation of the Efficacy and Safety of Calistar S for Transvaginal Pelvic Organ Prolapse Repair
Prospective long-term evaluation of the performance and safety of Calistar S for transvaginal pelvic organ prolapse repair in women with anterior POP with or without apical vaginal involvement
- Trial name
- CASPO (NCT03821142)
- Testing
- Transvaginal mesh for anterior pelvic organ prolapse repair
- Where
- 6 sites in Germany
- Volunteers
- 180 people
- Sponsor
- Promedon
Pelvic Organ Prolapse
Effect of Electroacupuncture on Symptoms of Female Pelvic Organ Prolapse(Level II - III)
The purpose of the study is to assess the efficacy and safety of electroacupuncture among women with pelvic organ prolapse(Level II - III), compared with sham electroacupuncture.
- Trial name
- EAPOP (NCT04589715)
- Testing
- electroacupuncture
- Volunteers
- 160 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Pelvic Organ Prolapse (POP)
Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial
Pelvic organ prolapse is common among women with a prevalence that has been estimated to be as high as 30%. Pelvic organ prolapse often involves a combination of support defects involving the anterior, posterior and/or apical…
- Trial name
- OPTIMAL (NCT00597935)
- Testing
- SSLF, ULS, PMT
- Where
- 9 sites in United States
- Volunteers
- 374 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Urinary Retention, Pelvic Organ Prolapse
Urinary Catheter Self-Discontinuation After Urogynecology Surgery
The goal of this randomized clinical trial is to determine if removal of transurethral urinary catheters by patients at home is as safe as catheter removal in the office following urogynecologic surgery.
- Conditions
- Urinary Retention, Pelvic Organ Prolapse, Stress Urinary Incontinence, Catheter Related Complication
- Trial name
- CATH (NCT05860634)
- Testing
- Catheter self-discontinuation
- Where
- 4 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Pelvic Floor Disorders, Sexual Dysfunction
A Multi Center Study to Validate a Condition-specific Measure of Sexual Health in Women With Pelvic Floor Disorders
Study Aims: 1. To validate a new measure of sexual function and activity in women with PFDs; 2. To establish the responsiveness to change of the new measure.
- Conditions
- Pelvic Floor Disorders, Sexual Dysfunction, Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT00952406
- Testing
- Survey
- Where
- 14 sites in United States, United Kingdom
- Volunteers
- 877 people
- Sponsor
- International Urogynecological Society
Pelvic Organ Prolapse
A Novel Approach to Posterior Mesh Fixation in Laparoscopic Sacral Colpopexy
This randomized controlled study is designed to test the non inferiority of no attachment of posterior mesh compared to fixation of posterior mesh to the vagina in laparoscopic sacral colpopexy in terms of anatomical correction…
- Trial name
- NCT04358978
- Testing
- laparoscopic sacral colpopexy with posterior mesh no attachment, laparoscopic sacral colpopexy with posterior mesh attachment
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Catholic University of the Sacred Heart