Clinical trials: Pelvic Prolapse
Sensation of Inadequate Defecation, Rectal Prolapse
Surgical Treatment of Obstructed Defecation Syndrome
Obstructed Defecation is a profoundly disabling condition. Many different surgical procedures has been introduced to treat patients affected by this disease. The most used are STARR and ventral rectopexy.
- Conditions
- Sensation of Inadequate Defecation, Rectal Prolapse, Rectocele
- Trial name
- PRO-REST (NCT01899209)
- Testing
- STARR, Laparoscopic Ventral Rectopexy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Postoperative Urinary Retention
The Role of Sugammadex in Posotoperative Urinary Retention in Patients Undergoing Pelvic Floor Reconstructive Procedures
The Investigator will perform a single-institution randomized double-blinded controlled trial comparing intraoperative Sugammadex vs.
- Trial name
- NCT05664633
- Testing
- Sugammadex
- Sponsor
- West Virginia University
Pelvic Organ Prolapse
Vaginally Assisted Laparoscopic Sacropolpopexy
Introduction and Hypothesis: Vaginally assisted laparoscopic sacrocolpopexy (VALS), which is a combined surgical approach where a vaginal hysterectomy is initially performed, followed by transvaginal placement of synthetic mesh…
- Trial name
- VALS (NCT04332315)
- Testing
- Vaginally assisted laparoscopic sacrocolpopexy
- Volunteers
- 87 people
- Sponsor
- Bezmialem Vakif University
Postmenopausal Period, Vaginal Atrophy
Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser
The aim of study is characteristic of changes in the vaginal wall after treatment of neodymium laser radiation with a wavelength of 1064 nm.
- Conditions
- Postmenopausal Period, Vaginal Atrophy, Vaginal Prolapse
- Trial name
- NCT05335317
- Testing
- Laser Treatment, Topical hormone estriol, Сlinical blood analysis
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- MeLSyTech, Ltd
Pelvic Organ Prolapse, Urinary Tract Infections
Study to Assess Duration of Indwelling Catheter After Sacrocolpopexy
Objectives The objective of this study is to help identify the best practice regarding the use of indwelling catheter after minimally invasive urogynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Urinary Tract Infections, Urinary Retention
- Trial name
- CARESS (NCT02189291)
- Testing
- Immediate catheter removal, Post op day 1 catheter removal
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- Oregon Health and Science University
Vaginal Prolapse
Avaulta Versus Anterior Repair
Summary: Vaginal prolapse is a well-known disease and is observed in approximately 11% of all postmenopausal women and tending to increase with age.
- Trial name
- NCT00627549
- Testing
- Avaulta (surgical procedure using a mesh implant), Conventional surgery (anterior repair)
- Where
- Denmark
- Sponsor
- Zealand University Hospital
Catheter-Associated Urinary Tract Infection
Nitrofurantoin Administration for the Prevention of Short-Term Catheter Associated Urinary Tract Infection After Pelvic Surgery
The specific aim of this randomized double-blind placebo-controlled trial is to evaluate the efficacy of administration of nitrofurantoin prophylaxis after catheter discontinuation for the prevention of catheter-associated…
- Trial name
- NAUTICA (NCT03287089)
- Testing
- Nitrofurantoin 100 MG
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Wake Forest University Health Sciences
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study
The goal of this study is to compare vaginal mesh surgery with abdominal robotic-assisted mesh surgery for the treatment of genital prolapse in women.
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Mesh Reinforcement, Vaginal Apex/Uterine Prolapse
- Trial name
- NCT07359755
- Testing
- Vaginal mesh surgery for apical prolapse, Robotic-assisted abdominal mesh surgery with Upsylon device (Boston Scientific - USA) for vaginal apical prolapse
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- University of Sao Paulo General Hospital
Pelvic Organ Prolapse, Patient Satisfaction
The Impact of a Redesigned Handout for Robotic Sacrocolpopexy on Patient Preoperative Preparedness and Satisfaction
The goal of this clinical trial is to learn if a new preoperative handout for patients undergoing robotic sacrocolpopexy will improve patient sense of preparedness and satisfaction in comparison to the previously used handout.
- Trial name
- NCT06934304
- Testing
- new preoperative handout, old preoperative handout
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Texas Southwestern Medical Center
Vaginal Prolapse
Prospective Observational Prolapse Study
The rationale of the study is to investigate the results of a prolapse treatment in adult women with a vaginal prolapse. The investigators will investigate this by taking questionnaires in women undergoing a surgical prolapse…
- Trial name
- NCT04701047
- Testing
- vaginal pessary, Vaginal prolapse surgery
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Ghent
Pelvic Organ Prolapse
Clinical and Urodynamic Evaluation of Surgical Repair of Pelvic Organ Prolapse Associated With Lower Urinary Tract Symptoms
To assess the urinary symptoms and urodynamic findings concomitant with Pelvic organ prolapse before and after surgical treatment and to define the role of urodynamic study in treatment decision making.
- Trial name
- NCT04793126
- Testing
- Urodynamic study
- Volunteers
- 83 people
- Sponsor
- Ain Shams University
Uterine Prolapse, Bladder Diseases
Pelvic Floor Muscle Training (PFMT) in Treatment and Prevention of POP (POP Study)
Background: The pelvic floor muscles (PFM) are located inside the pelvis, surrounding the urethra, vagina and rectum. They provide structural support for the pelvic organs.
- Conditions
- Uterine Prolapse, Bladder Diseases, Cystocele, Rectocele
- Trial name
- NCT00271297
- Testing
- Pelvic floor muscle training
- Where
- Norway
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Pelvic Organ Prolapse
Postoperative Virtual Clinical Encounters
Postoperative follow up is necessary following any surgical procedure and has been conducted in the same manner since the field of surgery began.
- Trial name
- NCT04138810
- Testing
- VCE, Survey
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Pennsylvania
Pelvic Organ Prolapse, Sexual Dysfunction
The Association of Pelvic Organ Prolapse Severity and Urinary Symptoms and Sexual Function
Women with pelvic organ prolapse often accompany with urinary symptoms or sexual dysfunction, and analyzing the association will be helpful to identify the indication of proper management.
- Conditions
- Pelvic Organ Prolapse, Sexual Dysfunction, Lower Urinary Tract Symptoms
- Trial name
- NCT01776580
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postoperative Urinary Tract Infection, Pelvic Organ Prolapse
Gentamicin Intravesical Efficacy for Infection of Urinary Tract
Urinary tract infection (UTI) is a common problem after surgery for pelvic organ prolapse and stress urinary incontinence. This prospective, randomized, single-masked (subject), two-parallel armed study aims to determine the…
- Conditions
- Postoperative Urinary Tract Infection, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- GIVEIT (NCT04246996)
- Testing
- gentamicin sulfate, Catheter clamping only
- Where
- 2 sites in United States
- Volunteers
- 370 people
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse (POP), Urinary Incontinence , Stress
A Novel Laparoscopic Apical Promontofixation Technique With Simultaneous Perineal Reconstruction for Patients With Symptomatic Pelvic Organ Prolapse
Pelvic organ prolapse in women is a common gynecological condition worldwide, with prevalence reported by different authors ranging from 15% to 50%.
- Conditions
- Pelvic Organ Prolapse (POP), Urinary Incontinence , Stress, Urinary Incontinence (UI), Female Sexual Dysfunction (FSD)
- Trial name
- NCT07271862
- Testing
- Laparoscopic sacrocolpopexy., Laparoscopic apical promontofixation combined with simultaneous vaginal and perineal reconstruction using native tissues.
- Where
- Latvia
- Volunteers
- 60 people
- Sponsor
- Riga East Clinical University Hospital
Nocturia, Pelvic Organ Prolapse
Severe Pelvic Organ Prolapse and Post-Obstructive Diuresis (SOPPO) Pilot Study
In our experience, women with severe pelvic organ prolapse (POP) frequently have bothersome nocturia. The International Continence Society (ICS) defines nocturia as "having to wake at night one or more times to void." Though some…
- Trial name
- SOPPO (NCT02060331)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loyola University
Pelvic Organ Prolapse
Total Laparoscopic Hysterectomy With Sacrocolpopexy Versus Total Laparoscopic Hysterectomy With Lateral Suspension in Patients With Pelvic Organ Prolapse
This prospective randomized surgical trial is designed to compare objective and subjective outcomes of total laparoscopic hysterectomy with sacrocolpopexy versus total laparoscopic hysterectomy with lateral suspension for the…
- Trial name
- NCT03722563
- Testing
- total laparoscopic hysterectomy with sacrocolpopexy, total laparoscopic hysterectomy with lateral suspension
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Antalya Training and Research Hospital
Pelvic Organ Prolapse
Evaluation of the Results of Lateral Suspension Surgeries Performed With the V-NOTES (Vaginal-Natural Orifice Transluminal Endoscopic Surgery) Technique
It was aimed to evaluate the quality of life and sexual function of patients by Pre- and postoperative POP-Q (Pelvic Organ Prolapse Quantification) staging and PISQ-12 (Pelvic Organ Prolapse/Urinary Incontinence Sexual…
- Trial name
- NCT05066737
- Testing
- lateral suspension via V-NOTES surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pelvic Organ Prolapse, Urinary Incontinence
A Study of Robotic Assisted Laparoscopic Sacral Colpopexy Using Alyte Mesh
Robotic approach to sacral colpopexy is a relatively new procedure. The literature is scarce in regard to long term outcomes. This advanced procedure is offered at Morristown Memorial.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Mesh Erosion
- Trial name
- ALYTE (NCT01320644)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System