Clinical trials: Pelvic Prolapse
Rectal Prolapse
Anterior Versus Posterior Laparoscopic Mesh Rectopexy For Rectal Prolapse; a Randomized Controlled Trial.
Aim of this work is to compare results between Laparoscopic Anterior Mesh Rectopexy and Laparoscopic Posterior Mesh Rectopexy for patients with rectal prolapse by assessment of operative time, intraoperative blood loss …
- Trial name
- NCT03026738
- Testing
- Laparoscopic anterior mesh rectopexy, Laparoscopic posterior mesh rectopexy, polypropylene mesh
- Volunteers
- 30 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse, Stress Urinary Incontinence
Impact of Decision Aids in Urogynecology
To evaluate how patient knowledge and confidence in decision making can be impacted by shared decision making in common urogynecology conditions.
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Overactive Bladder
- Trial name
- NCT04369404
- Testing
- Pelvic organ prolapse decision aid, Stress urinary incontinence decision aid, Overactive bladder decision aid
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Massachusetts General Hospital
Pelvic Organ Prolapse
How Low Can You Go
This is a randomized controlled trial to determine if lower intraabdominal operating pressure reduces post-operative pain in patients scheduled to undergo laparoscopic uterosacral suspension surgery of the uterus or vaginal vault.
- Trial name
- NCT07786337
- Testing
- Standard insufflation, Low insufflation
- Volunteers
- 164 people
- Sponsor
- University of Calgary
Urogenital Prolapse
LAparoscopic Preventive PRErectal Mesh
Urogenital prolapse is a frequent and invalidating pathology in women, involving the anterior vaginal wall and the uterus in most cases. Posterior vaginal wall prolapse is present in only 50% of cases.
- Trial name
- LAPREM (NCT03766048)
- Testing
- Single-Anterior-Mesh, SAM, Double-Mesh, DM
- Where
- 9 sites in France
- Volunteers
- 834 people
- Sponsor
- University Hospital, Lille
Vaginal Prolapse
Treatment Outcomes of Vaginal Prolapse Repair
Chart review conducted on all patients having had Prolift surgery since 2005 by Dr. Lary Sirls, Dr. Predeep Nagaraju and Dr. Kenneth Peters at William Beaumont Hospital.
- Trial name
- NCT00679276
- Testing
- Prolift
- Volunteers
- 291 people
- Sponsor
- Corewell Health East
Pelvic Organ Prolapse
Preoperative Oestrogen in Postmenopausal Women With Pelvic Organ Prolapse
Introduction With increasing age the incidence of pelvic organ prolapse (POP) rises and will increase substantially in the future according to forecasting studies.
- Trial name
- NCT03779633
- Testing
- Linoladiol Estradiol
- Where
- 2 sites in Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Pelvic Organ Prolapse
Outcomes Following Vaginal Prolapse Repair and Mid Urethral Sling Trial
Pelvic organ prolapse is common among women with a prevalence that has been estimated to be as high as 30%. Prolapse may be corrected by surgery using either a vaginal or abdominal incision.
- Trial name
- OPUS (NCT00460434)
- Testing
- TVT
- Where
- 8 sites in United States
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- NICHD Pelvic Floor Disorders Network
Pelvic Organ Prolapse
Questionnaire of Lower Urinary Tract Symptoms Among Women Before and After Surgical Correction of Uterine Prolapse
. The study will include patients who underwent Pelvic reconstructive surgery for advanced pelvic organ prolapse (POP-Q ≥ 3). Data regarding preoperative evaluation, surgical procedure, and post-operative management will be…
- Trial name
- NCT06260436
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pelvic Organ Prolapse
Laparoscopic Sacrocolpexy Versus Lateral Suspension
Surgical treatment of genital prolapse can be performed by laparoscopic surgery or by vaginal surgery, with or without using meshes.
- Trial name
- SUSPENSION (NCT03582852)
- Testing
- Surgical treatment of genital prolapse
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cystocele, Cystocele, Midline
Continuous Stitches Versus Simple Interrupted Stitches for Anterior Colporrhaphy
The anterior vaginal wall is the segment most commonly affected by prolapse. Traditionally, anterior vaginal wall prolapse is repaired via anterior colporrhaphy (native tissue repair), which is known to have a high recurrence…
- Conditions
- Cystocele, Cystocele, Midline, Vaginal Prolapse, Prolaps Bladder
- Trial name
- NCT05449054
- Testing
- Anterior colporrhaphy
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- Medical University of Vienna
Prolapse Uterovaginal, Prolapse Bladder
Laparoscopic Central and Anterior Compartment Prolapse Surgery: A Meshless Sacrocolpopexy Technique
Mesh is widely applied in the abdominal approach to pelvic organ prolapse surgery, and sacrocolpopexy-sacrohysteropexy is the gold standard application, particularly for central compartment abnormalities.
- Conditions
- Prolapse Uterovaginal, Prolapse Bladder, Laparoscopy
- Trial name
- NCT05558852
- Testing
- Laparoscopic Meshless Sacrocolpopexy Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Diverticulum, Colon, Colorectal Neoplasms
A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing device in routine clinical practice at 4-6 centers.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- NCT01880918
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- novoGI
Pelvic Organ Prolapse, Stage III and IV High Grade Pelvic Organ Prolapse
Efficacy/Safety of Urogynecology Synthetic Mesh Surgery
This is a retrospective cohort study, aiming at analyzing the efficacy and safety of mesh surgery in pelvic organ prolapse. The synthetic mesh for pelvic organ prolapse include transvaginal mesh or laparotomy, laparoscope, or…
- Trial name
- NCT05682989
- Testing
- Urodynamic investigations before and after a mesh surgery protocol., Urodynamic investigations before and after a robotic-assisted sacrocolpopexy protocol., Urodynamic investigations before and after a hysterectomy with trans-vaginal mesh repair
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Mackay Medical College
Urinary Incontinence, Cystocele
Enhanced Recovery Protocol in Urogynecologic Surgery
Enhanced recovery after surgery (ERAS) has been shown to improve postoperative outcomes in a variety of surgical conditions. However, data regarding its role in urogynecologic surgery is limited.
- Conditions
- Urinary Incontinence, Cystocele, Rectocele, Pelvic Organ Prolapse
- Trial name
- NCT04175782
- Testing
- Enhanced recovery after surgery (ERAS) protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pelvic Organ Prolapse
Factors Affecting Perioperative Outcomes
The specific aim of this study is to determine if pre-existing depression and anxiety affect perioperative outcomes measures patients undergoing surgery for pelvic organ prolapse.
- Trial name
- NCT01530191
- Where
- United States
- Sponsor
- University of Oklahoma
Pelvic Organ Prolapse
Comparison of Postoperative Outcomes of Laparoscopic Lateral Suspension and V-NOTES Lateral Suspension With the Salman Ketenci Gencer Technique
Comparison of Early Postoperative Outcomes of Patients Undergoing Laparoscopic Lateral Suspension and V-NOTES Lateral Suspension with the Salman Ketenci Gencer Technique
- Trial name
- NCT06802497
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pelvic Organ Prolapse
Post-operative Cognitive Function Following Pelvic Floor Surgery
The aim of this study is to assess cognitive function before and after surgery for pelvic organ prolapse using sensitive tests of various neurocognitive domains.
- Trial name
- NCT04554550
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Pennsylvania
Pelvic Organ Prolapse
Physical Therapy on Pelvic Organ Prolapse
OBJECTIVE: To evaluate the effectiveness of an individualized pelvic floor physiotherapy programme combined with lifestyle education compared with lifestyle education alone in women with stage I or II pelvic organ prolapse (POP).
- Trial name
- PT-POP (NCT03244397)
- Testing
- Physical therapy + educational strategy, Educational strategy
- Where
- 2 sites in Spain
- Volunteers
- 120 people
- Sponsor
- University of Alcala
Pelvic Organ Prolapse
Difference in Pain, Quality of Life Following Vaginal Hysterectomy With Vaginal Reconstruction Versus Robotic Colpopexy?
The purpose of this study is to to determine if there is a difference in patient related outcomes of pain and quality of life following vaginal hysterectomy with vaginal prolapse repair compared to robotic-assisted repair.
- Trial name
- NCT02049996
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Leiomyoma, Incontinence
Uterine Artery Embolization and Pelvic Floor Symptoms
The objective of this study is to determine whether women who are already receiving treatment for their fibroids (ie. UAE) demonstrate improvement in urinary symptoms and sexual dysfunction as well.
- Conditions
- Leiomyoma, Incontinence, Prolapse
- Trial name
- NCT00827645
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center