Clinical trials: Pelvic Prolapse
Urinary Incontinence, Stress, Uterine Prolapse
Colpopexy and Urinary Reduction Efforts (CARE) Protocol
Pelvic organ prolapse occurs when the muscles holding pelvic organs (e.g., the uterus or bladder) weaken and the organs fall or slide down into the vagina. Pelvic organ prolapse can be corrected with surgery.
- Conditions
- Urinary Incontinence, Stress, Uterine Prolapse, Vaginal Prolapse
- Trial name
- CARE (NCT00065845)
- Testing
- Burch urethropexy at time of sacrocolpopexy
- Where
- 7 sites in United States
- Volunteers
- 322 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Prolapse Pelvic, Hysterectomy
Vaginal Natural Orifice Transluminal Endoscopic (vNOTE) Hysterectomy With Uterosacral Suspension
As the adoption of Vaginal natural orifice transluminal endoscopic surgery (vNOTES) expands, attention is shifting from feasibility studies to the refinement of surgical steps that optimize long-term pelvic health.
- Trial name
- VENUS (NCT07413861)
- Testing
- Uterosacral suspension, Hysterectomy by vNOTES approach
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Anterior Vaginal Wall Prolapse With/Without Apical/Uterine Descent
Multicenter, Prospective, Non-randomized, Single-arm, Interventional Study for the Evaluation of the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
A prospective, single arm, multi-center clinical study to evaluate the safety and performance of the SRS (Lyra Medical) vaginal mesh in POP patients
- Trial name
- NCT03195361
- Testing
- SRS - Self Retaining Support system
- Where
- 3 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Lyra Medical Ltd.
Rectal Prolapse, Fecal Incontinence
Clinical Outcomes of Rectopexy for Rectal Prolapse
This study evaluates the clinical outcomes of patients who underwent rectopexy for rectal prolapse, ODS or FI. Rectopexy is a surgical procedure used to restore and fix the rectum in its normal position.
- Conditions
- Rectal Prolapse, Fecal Incontinence, Rectopexy, Obstructive Defecation Syndrome
- Trial name
- NCT07848308
- Testing
- anterior mesh rectopexy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- Lukas Marti
Pelvic Organ Prolapse, Prolapse
Early Feasibility Study of the Reia Vaginal Pessary
This is an early feasibility open-label non-randomized trial to obtain preliminary information about the function and effectiveness of a novel vaginal pessary for the use in women who suffer from symptoms of pelvic organ prolapse…
- Trial name
- NCT04275089
- Testing
- Reia Vaginal Pessary
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Reia, LLC
Benign Uterine Disease
Total Versus Subtotal Abdominal Hysterectomy
319 Women undergoing hysterectomy for benign (not cancer) indications were randomly allocated to 2 types of surgery (Total (TAH) and Subtotal (SAH)) abdominal hysterectomy 15 years ago.
- Trial name
- NCT01880710
- Testing
- Subtotal hysterectomy, Total Hysterectomy
- Where
- Denmark
- Volunteers
- 319 people
- Sponsor
- Nykøbing Falster County Hospital
Pelvic Organ Prolapse
Composite Outcomes of Mesh vs Suture Techniques for Prolapse Repair: A Randomized Controlled Multicentre Trial
This is a Canadian, multi-centre, double-blind randomized controlled trial of an innovative vaginal surgery technique for correction of pelvic organ prolapse (POP) in women.
- Trial name
- COMET (NCT02965313)
- Testing
- SSLS Procedure, BSSVF-M Procedure
- Where
- Canada
- Volunteers
- 358 people
- Sponsor
- University of British Columbia
Rectal Prolapse
Continuous Locked Non-barbed Suture for Mesh Fixation During Laparoscopic Ventral Rectopexy for Severe Rectal Prolapse
This prospective randomized pilot study is aimed to verify if the operative time of a standard laparoscopic ventral rectopexy for the treatment of severe rectal prolapse could be further reduced using a continuous locked suture…
- Trial name
- NCT05254860
- Testing
- LPS Ventral Rectopexy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico