Clinical trials: Pelvic Prolapse
Rectal Prolapse, Pelvic Organ Prolapse
Value of Robotic Rectopexy for the Treatment of Complex Pelvic Floor Dysfunction
The purpose of this randomized double blind controlled study is to assess the value of robotics for the treatment of complex pelvic floor dysfunction.
- Trial name
- NCT01346436
- Testing
- Minimally invasive rectopexy
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Nicolas C. Buchs
Rectal Prolapse
Frailty Increase Rectal Prolapse Recurrence
evaluate recurrent RP in relation to frailty
- Trial name
- NCT07230275
- Testing
- LVMR for RP, PSR for RP
- Volunteers
- 342 people
- Sponsor
- Zagazig University
Pelvic Organ Prolapse, Female Urogenital Diseases
Pelvic Organs Prolapse Treatment Using Neodymium Laser
The aim of this prospective study is investigation of efficiency and safety of medical device "Magic Max" ("Magic Gyno" from August 2024) for preoperative treatment of pelvic organs prolapse I-II degree of severity.
- Trial name
- NCT05000957
- Testing
- Laser Treatment, Blood analysis, Сlinical urine test
- Where
- Russia
- Volunteers
- 129 people
- Sponsor
- MeLSyTech, Ltd
Pelvic Organ Prolapse, Constipation
Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy
Compare changes in bowel function before, 6 months and one year after Robotic-assisted laparoscopic sacral colpopexy. Compare objective anatomic outcomes before, 6 months and one year after Robotic-assisted laparoscopic sacral…
- Conditions
- Pelvic Organ Prolapse, Constipation, Bowel Dysfunction, Irritable Bowel Syndrome
- Trial name
- NCT01618292
- Testing
- Robotic sacral colpopexy
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Atlantic Health System
Urinary Retention, Pelvic Organ Prolapse
Early Versus Late Voiding Trials After Prolapse Repair
The primary aim of this study is to determine if normal bladder function (the ability to empty the bladder during spontaneous urination) after surgical repair of pelvic organ prolapse returns faster in patients who have a…
- Trial name
- NCT02739256
- Testing
- Retrograde voiding trial
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Pittsburgh
Pelvic Organ Prolapse
Comprehensive Nursing Care Protocol for Women With Pelvic Organ Prolapse and Urinary Incontinence: A Global Perspective
Pelvic organ prolapse is the descent of pelvic structures into the vagina due to ligament or muscular weakness. Pelvic organ prolapse (POP) is subcategorized according to the compartment of descent.
- Trial name
- Nurse Protocol (NCT06639217)
- Testing
- a comprehensive nursing care protocol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
Rectal Prolapse
Recurrence of Dyschezia in Rectal Prolapse, Rectocele and Elytrocele
Prolapse of the rectum is a pathology that preferentially affects older women with a significant impact on quality of life. A very large number of therapeutic approaches can be proposed (functional treatment, surgical techniques…
- Trial name
- PEXITY (NCT04627610)
- Testing
- Rectal prolapse, rectocele and elytrocele
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Grenoble
Pelvic Organ Prolapse, Pelvic Floor Disorders
Pelvic Floor Exercise Before Surgery in Women With Pelvic Organ Prolapse
The lifetime risk for a woman to undergo surgery for either vaginal prolapse or urinary incontinence is high. There are many different surgical techniques for treatment of prolapse, but there is a lack of knowledge about factors…
- Trial name
- CONTRAPOP (NCT03064750)
- Testing
- pelvic floor exercises, Waiting list
- Where
- Norway
- Volunteers
- 151 people
- Sponsor
- St. Olavs Hospital
Uterine Prolapse, Urine Incontinence
The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.
Determination of fibrin clot properties along with thrombin generation in women after urigynecological surgery.
- Trial name
- NCT07295782
- Testing
- determination of fibrin clot properties
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Pelvic Floor Disorders, Vaginal Atrophy
Effect of Laser Therapy on Vaginal Tissue
Pelvic floor disorders, including prolapse, incontinence, and vulvovaginal atrophy decrease the quality of life of every fourth woman.
- Trial name
- NCT05898191
- Testing
- vaginal laser treatment
- Where
- Czechia
- Volunteers
- 15 people
- Sponsor
- Institute for the Care of Mother and Child, Prague, Czech Republic
Cystocele
UGYTEX® Mesh Versus Subvesical Plication in the Surgical Treatment of Bladder Prolapse
The main purpose of this study is to evaluate the long-term (5-8 years) functional prolapse recurrence rate of the 147 patients enrolled, randomized and analyzed in the study PRO-CURE I.
- Trial name
- PRO-CURE II (NCT02255994)
- Testing
- UGYTEX, No mesh.
- Where
- 12 sites in France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
SMAD2, SMAD3
SMAD2, SMAD3 AND TGF-β GENE EXPRESSION IN URGE URINARY INCONTINENCE
Urge urinary incontinence (UUI) is a common health problem. Changes in collagen metabolism in pelvic support organs, such as uterosacral ligaments (USLs), might be responsible for the complex pathophysiology of UUI.
- Conditions
- SMAD2, SMAD3, TGF-β, Pelvic Organ Prolapse
- Trial name
- NCT04525105
- Testing
- SMAD2
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Muğla Sıtkı Koçman University
Internal Hemorrhoid, Rectal Prolapse
Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse
This clinical trial aims to evaluate the efficacy and safety of long needle and short needle in the treatment of internal hemorrhoids and rectal prolapse through CAES (Cap-assisted endoscopic sclerotherapy).
- Trial name
- NCT03917056
- Testing
- Cap-assisted endoscopic sclerotherapy using long needle, Cap-assisted endoscopic sclerotherapy using short needle
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Pelvic Organ Prolapse
The Influence of Using Vascularized Vaginal Flap on the Efficacy of Mesh-augmented Sacrospinous Hysteropexy
This is a prospective randomized controlled trial designed to compare the effectiveness and safety of two methods of pelvic floor reconstruction in patients with pelvic organ prolapse (POP): sacrospinous hysteropexy (SSHP) with…
- Trial name
- NCT06494982
- Testing
- Sacrospinous hysteropexy with the synthetic mesh, vaginal flap and anterior colporrhaphy, Sacrospinous hysteropexy with the synthetic mesh and anterior colporrhaphy
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Saint Petersburg State University, Russia
Pelvic Organ Prolapse, Urinary Incontinence
Continence After Vaginal Prolapse Surgery
Urinary incontinence after surgical correction of pelvic organ prolapse (POP) could occur. This is a condition that decreases both patients' satisfaction and quality of life.
- Trial name
- NCT05312047
- Testing
- Pelvic organ prolapse surgery
- Where
- 14 sites in Spain
- Volunteers
- 609 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pelvic Organ Prolapse, Urinary Incontinence
Mesh Debate Awareness Among Non-urogynecologists. A Practical Survey Study.
This study evaluates the awareness of mesh discussions in urogynecology among non-urogynecologists. A web-based questionnaire will be sent to four groups. Group-1 is King's College Hospital doctors.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Complication of Surgical Procedure
- Trial name
- Mesh_Survey (NCT04010162)
- Testing
- Mesh debate awareness survey
- Where
- Turkey (Türkiye)
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Uludag University
Cystocele
Lower Urinary Tract Symptoms Screening Questionnaire
The purpose of this study is to determine the validity of a screening tool which has been designed to detect the presence or absence of lower urinary tract symptoms in the general female population.
- Trial name
- LUTS-2 (NCT01616810)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Pelvic Organ Prolapse
Comparison of the Efficacy of Sacrocolpopexy, the Amreich-Richter Procedure and Transvaginal Mesh
Pelvic organ prolapse, POP, is a common health problem affecting up to 40% of women. Very little is known about the factors associated with surgical failure.
- Trial name
- SAME (NCT03053479)
- Testing
- Laparoscopic sacrocolpopexy, Transvaginal mesh procedure, Amreich-Richter procedure
- Where
- 7 sites in Czechia, Slovakia
- Volunteers
- 462 people
- Sponsor
- Charles University, Czech Republic
Pelvic Organ Prolapse, Cystocele
Effectiveness Prolift+M Versus Conventional Vaginal Prolapse Surgery
Pelvic organ prolapse is highly prevalent in the female population. The recurrence rate of pelvic organ prolapse after surgical treatment is high.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Rectocele, Uterine Prolapse
- Trial name
- VROUW2 (NCT02231099)
- Testing
- Prolift + M, conventional vaginal prolapse surgery
- Where
- 5 sites in Netherlands
- Volunteers
- 176 people
- Sponsor
- Radboud University Medical Center
Pelvic Organ Prolapse, Urinary Incontinence
Pelvic Organ Prolapse Repair Plus Mini-Sling Versus Pelvic Organ Prolapse Repair Alone
The investigators have performed colposacropexy in women with uterovaginal prolapse for many years with satisfactory results. This study was designed to compare whether, in the treatment of patients with uro-genital prolapse and…
- Trial name
- NCT01384084
- Testing
- POP repair plus mini-sling, POP repair
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University Of Perugia