Clinical trials: Pelvic Prolapse
Rectal Prolapse, Fecal Incontinence
Recurrence and Bowel Function After Laparoscopic Vaginorectopexy, a Modified Anterior Rectopexy
Several pelvic prolapses can render defecation difficulties and they are often treated with different surgical techniques. This study will evaluate a novel variation of a laparoscopic technique used to treat rectal prolapse that…
- Conditions
- Rectal Prolapse, Fecal Incontinence, Defecation Disorder, Enterocele
- Trial name
- NCT06330857
- Testing
- Laparoscopic vaginorectopexy
- Volunteers
- 25 people
- Sponsor
- Sahlgrenska University Hospital
Pelvic Organ Prolapse
Inflammation and Cellular Immunity in Vaginal Tissue in Patients With Pelvic Organ Prolapse
The aim of this study is to investigate the inflammatory and maturation processes of immature myeloid cells (IMC) in the vaginal tissue in women with advanced pelvic organ prolapse (POP) (stage III-IV) and in normal non-POP…
- Trial name
- NCT03748693
- Testing
- Hysterectomy, Colporrhaphy
- Volunteers
- 20 people
- Sponsor
- Hillel Yaffe Medical Center
Vaginal Prolapse
Physiologic Elasticity Changes During Pregnancy and After Labor.
Female pregnant patients in their 2nd trimester will be evaluated for vaginal elasticity using vaginal tactile imaging in addition to elasticity evaluation during the 3rd trimester and 6 weeks postpartum.
- Trial name
- NCT03930290
- Testing
- Vaginal tactile imager
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Rambam Health Care Campus
Pelvic Organ Prolapse, Urinary Incontinence,Stress
Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence
This study evaluates the addition of a laparoscopic Burch colposuspension procedure at the time of laparoscopic sacrocolpopexy to prevent stress urinary incontinence.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence,Stress, Urinary Incontinence, Urge, Bowel Dysfunction
- Trial name
- MICRO (NCT03841513)
- Testing
- Laparoscopic Burch Colposuspension
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Pelvic Organ Prolapse, Urinary Incontinence
Prospective Cohort Study of Robotic Assisted Laparoscopic Sacrocolpopexy Using MPATHY Restorelle Mesh
Robotic approach to sacral colpopexy is a relatively new procedure. The literature is scarce in regard to long term outcome. This advanced procedure is offered at Morristown Memorial.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Mesh Erosion
- Trial name
- MPATHY (NCT01320618)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse
Vaginal Microbiota as a Decisive Factor in Vaginal Prosthetic Surgery
Retrospective analysis of vaginal microbiota in the post-operative course of patient operated for genital prolapse with vaginal mesh with or without mesh related complication
- Trial name
- NCT02890498
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Prolapse; Female
Concomitant Posterior Colporrhaphy on Bowel Functions in Pelvic Organ Prolapse Repair
Compare the changes of preoperative and postoperative posterior colporrhaphy.
- Trial name
- NCT06128291
- Testing
- posterior colporrhaphy
- Where
- Taiwan
- Volunteers
- 283 people
- Sponsor
- National Taiwan University Hospital
Uterine Prolapse
Abdominal Versus Vaginal Hysteropexy
This study will compare the vaginal versus the abdominal approach for the management of uterine prolapse
- Trial name
- NCT03494582
- Testing
- Sacral Hysteropexy, sacrospinous Hysteropexy
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Ain Shams Maternity Hospital
Pelvic Organ Prolapse, Urinary Stress Incontinence
Comparison of the Result of TVT Performed at the Time of Prolapse Surgery or 3 Months After
It is unknown whether it is best to do the TVT( procedure for urinary stress incontinence in women) at the time of prolapse surgery or at a later date.
- Trial name
- NCT00308009
- Testing
- Vaginal Repair for prolapse, TVT procedure, TVT and Prolapse surgery
- Volunteers
- 194 people
- Sponsor
- Ullevaal University Hospital
Constipation by Outlet Obstruction, Pelvic Organ Prolapse
Early Safety of Resection Rectopexy and Sacrocolpopexy
Obstructive defecation syndrome (ODS) defines a disturbed defecation process frequently associated with pelvic organ prolapse (POP) in women.
- Conditions
- Constipation by Outlet Obstruction, Pelvic Organ Prolapse, Urinary Incontinence
- Trial name
- RRPSCPcomb (NCT05910021)
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- Evangelisches Klinikum Köln Weyertal gGmbH
Vaginitis Atropic, Pelvic Organ Prolapse
Vaginal Estrogens Comparative Trial on Pelvic Organ Prolapse Patients
To evaluate the difference of three vaginal estrogens creams comparative with placebo on improvement of hormonal cytology, local and systemic climacteric complaints, as well as its endometrial security.
- Conditions
- Vaginitis Atropic, Pelvic Organ Prolapse, Endometrial Hyperplasia
- Trial name
- NCT03032848
- Testing
- Conjugated Estrogen, Promestriene, Estriol
- Volunteers
- 69 people
- Sponsor
- Universidade Federal do Paraná
Female Sexual Dysfunction
Effect of Pelvic Organ Prolapse Surgeries on Female Sexual Function in Egyptian Women
study on female sexual function after different prolapse surgeries
- Trial name
- NCT03498443
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Pelvic Organ Prolapse, Genital Prolapse
i-Stitch for Bilateral Sacrospinous Ligament Fixation (SSLF)
The purpose of the clinical investigation is to generate clinical data to substantiate the safety and performance of the i-Stitch device for bilateral sacrospinous ligament fixation (SSLF) in pelvic organ prolapse (POP) repair.
- Trial name
- i-StitchSSLF (NCT06805006)
- Testing
- SSLF
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Anterior Vaginal Wall Prolapse, Cystocele
Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis
The purpose of this study is to evaluate the success rate of cystocele repair using polypropylene mesh or porcine dermis compared to that of anterior colporrhaphy in a prospective randomized fashion.
- Conditions
- Anterior Vaginal Wall Prolapse, Cystocele, Pelvic Organ Prolapse
- Trial name
- OARS (NCT01393171)
- Testing
- Polypropylene mesh (Polyform by Boston Scientific), Porcine Dermis (Pelvicol by CRBard), Anterior Colporrhaphy
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse
Follow-up Study After Manchester Operation for Pelvic Organ Prolapse
Native tissue repair for pelvic organ prolapse (POP) is the predominant surgical technique in the investigators department and the Manchester operation the preferred procedure.
- Trial name
- MAP-POP (NCT02246387)
- Testing
- Manchester Operation
- Where
- Norway
- Volunteers
- 209 people
- Sponsor
- Oslo University Hospital
Voiding Dysfunction
Randomized Controlled Trial of Cystocele Plication Risks ("CPR Trial"): A Pilot Study
Up to 50% of patients undergoing pelvic floor repair experience short-term postoperative voiding dysfunction, increasing the length of hospitalization, cost and anxiety among patients.
- Trial name
- CPR (NCT01197248)
- Testing
- Cystocele plication, No Plication
- Volunteers
- 40 people
- Sponsor
- Mount Sinai Hospital, Canada
Pelvic Organ Prolapse
Day Case Laparoscopic Sacrocolpopexy, a New Management
Facing the stakes of hospital beds, this study assessed day case variant technic of laparoscopic sacrocolpopexy with or without robotic assistant.
- Trial name
- NCT03607344
- Testing
- Cohort
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Urodynamic Stress Incontinence in Severe Cystocele Women
Evident, Occult and no Demonstrated USI and UDS Findings in Women With ≥Stage II Cystocele
Prevalence rates of urodynamic urinary incontinence (USI) subtypes and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical…
- Trial name
- NCT03613311
- Testing
- Urodynamic study
- Volunteers
- 480 people
- Sponsor
- National Taiwan University Hospital
Rectocele
Barbed Suture Versus Non-Barbed Suture for Posterior Colporrhaphy
The aim of this randomized clinical trial is to compare barbed suture versus non-barbed suture at the time of posterior repair on postoperative pain scores as measured by a visual analog scale (VAS) at 6 weeks.
- Trial name
- NCT04658784
- Testing
- 2-0 dioxanone, glycolide and trimethylene carbonate, 2-0 polydioxanone
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Wake Forest University Health Sciences
Urodynamic Stress Incontinence, Detrusor Overactivity
USI and/or DO in Women With Cystocele Before and After Cystocele Repair
The changes of lower urinary tract function after cystocele repair are important for perioperative consultation and management. Thus, the aim of this retrospective study was to evaluate the prevalence of urodynamic stress…
- Trial name
- NCT04978714
- Testing
- Cystocele repair
- Where
- Taiwan
- Volunteers
- 483 people
- Sponsor
- National Taiwan University Hospital