Clinical trials: Pelvic Prolapse
Prolapse, Vaginal, Prolapse, Uterine
Impact of Preop Video on Patient Anxiety
To determine whether a pre-operative educational video has an impact on the anxiety of patients undergoing vaginal prolapse surgery
- Conditions
- Prolapse, Vaginal, Prolapse, Uterine, Prolapse; Female
- Trial name
- NCT05633901
- Testing
- Educational Video, Standard Counseling
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
A Comparison Between Vaginal Sacrospinous Ligament Fixation and Laparoscopic Uterosacral Ligament Suspension as a Uterine Preserving Surgery for Pelvic Organ Prolapse
The investigators present a literature review evaluating the current place of sacrospinous hysteropexy in the surgical management of pelvic organ prolapse.
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Hysterectomy
- Trial name
- POP-Q USS USLS (NCT06982157)
- Where
- Israel
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Pelvic Organ Prolapse, Rectocele
Multicenter Ventral Mesh Rectopexy Registry Collaborative
The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal…
- Conditions
- Pelvic Organ Prolapse, Rectocele, Enterocele, Rectal Prolapse
- Trial name
- M2R2 (NCT05918367)
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Genitourinary Syndrome of Menopause (GSM)
Vaginal Platelet-Rich Plasma and Vaginal Histology in Genitourinary Syndrome of Menopause
This study evaluates whether subepithelial injection of autologous platelet-rich plasma (PRP) into the vaginal wall produces histological changes consistent with tissue regeneration in postmenopausal women with genitourinary…
- Trial name
- NCT07905820
- Testing
- Autologous Platelet-Rich Plasma (PRP), 0.9% sodium chloride (normal saline)
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Pelvic Organ Prolapse
SORD-BILL Vs Conventional Options During Sacral Colpopexy for POP
This prospective randomized pilot study is aimed to verify if the operative time of a standard laparoscopic sacral colpopexy associated to subtotal hysterectomy for the treatment of POP could be further reduced using PKS BILL…
- Trial name
- NCT02479685
- Testing
- PKS BILL-PKS PlasmaSORD Versus Conventional surgical techniques
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Catholic University of the Sacred Heart
Pelvic Organ Prolapse
Soft Tissue Graft for Repair of Pelvic Organ Prolapse
The purpose of this Study is to collect information about the performance of the Surgisis® Soft Tissue Graft ("Study Product") for the repair of pelvic organ prolapse in women.
- Trial name
- POP (NCT01827774)
- Testing
- Surgisis® Soft Tissue Graft
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Cook Group Incorporated
Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse
Efficacy of Platelet Rich Plasma on Pelvic Floor Muscle Strength and Recurrence Rate in Pelvic Organ Prolapse Surgery
Pelvic organ prolapse (POP) is a common pelvic floor disorder associated with impaired quality of life and considerable postoperative recurrence following native tissue repair.
- Conditions
- Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Platelet Rich Plasma Injection
- Trial name
- NCT07746739
- Testing
- POP surgery adjunctive PRP
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Andalas University
Pelvic Organ Prolapse
Caregiver Support and Post-operative Convalescence
This is a prospective cohort study designed to investigate the impact of home caregiver support on post-operative convalescence in patients undergoing same day discharge after major urogynecologic surgery.
- Trial name
- NCT04897061
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pelvic Organ Prolapse
Evaluation of Anatomical Results and Sexual Functions After Unilateral and Bilateral Laparoscopic Suture Sacro-hysteropexy Operations
The study was planned as prospective and randomized. For the study, patients will be randomized into two groups as unilateral and bilateral suture sacro-hysteropexy operations.
- Trial name
- NCT06341088
- Testing
- unilateral suture sacro-hysteropexy, bilateral suture sacro-hysteropexy
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Rectal Prolapse
Modified Perineal Linear Stapler Resection for External Rectal Prolapse: a Novel Approach
from December 2016 to July 2019, 36 elderly co-morbid patients with rectal prolapse were involved in this study which is performed in the GIT surgery unit of Zagazig University Hospital.
- Trial name
- NCT04184310
- Testing
- Modified perineal linear stapler resection for external rectal prolapse
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Zagazig University
Pelvic Organ Prolapse
Prospective Randomized Study to Compare Results of Pelvic Organ Prolapse Repair With One Versus Two Vaginal Meshes
The purpose of this study is to compare anatomical differences, quality of life and sexual function and complications rate between apical support with one anterior vaginal mesh versus repair with two separate meshes.
- Trial name
- NCT02536001
- Testing
- One mesh Endofast reliant system, two meshes Endofast reliant system
- Volunteers
- 100 people
- Sponsor
- Ziv Hospital
Sacral Colpopexy, Pelvic Organ Prolapse
Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction
The correction of the pelvic organ protrusion is aimed at restoring the pelvic floor functional status and ultimately improving the patient's quality of life.
- Trial name
- SEXQ (NCT01320631)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Vaginal Delivery, Pelvic Organ Prolapse
EASE: The Materna Prep Pivotal Study
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery.
- Trial name
- NCT03973281
- Testing
- Materna Prep Device, Standard of Care (SOC)
- Where
- 22 sites in United States
- Volunteers
- 420 people
- Sponsor
- Materna Medical
Rectal Prolapse
What Benefit With a New Stapler Device in the Surgical Treatment of Obstructed Defecation?
This randomized study was designed to compare the 2 year clinical and functional results with the STARR procedure using a new curved cutter stapler or the same operation done with 2 traditional circular staplers.
- Trial name
- NCT00810745
- Testing
- starr
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- University of Milan
Prolapse, Vaginal
Women's Knowledge and Attitudes to Use of Mesh in Gynaecological Surgery
This is a questionnaire study that is being performed to ascertain the knowledge and attitudes of women towards use of mesh in gynaecological surgery.
- Trial name
- NCT03527082
- Testing
- Questionnaire
- Volunteers
- 150 people
- Sponsor
- Epsom and St Helier University Hospitals NHS Trust
Cystocele
RUG-WEAVING PLICATION IN CYSTOCELE TREATMENT
In this study was to compare the 2-year results of the Rug Wave plication technique, which it present as a natural tissue repair technique in cystocele, with the conventional technique in terms of both recurrence and patient…
- Trial name
- NCT07336108
- Testing
- rug weaving-like plication technique, group 2:conventional technique cystocele treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Rectocele, Pelvic Organ Prolapse
An Intervention to Improve Prolapse Using Femmeze® (v1)
The main purpose of the feasibility study is to identify the patient experience of Femmeze® which is a device aimed at improving posterior vaginal compartment prolapse (rectocele) for women with obstructive defaecation.
- Trial name
- Femmeze® (NCT02280382)
- Testing
- Femmeze®
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Royal Cornwall Hospitals Trust
Bladder Outlet Obstruction and Detrusor Underactivity in Women With Severe Cystocele
BOO and DU and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele
Prevalence rates of bladder outlet obstruction (BOO) and detrusor underactivity (DU) and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for…
- Trial name
- NCT03613324
- Testing
- Pad test
- Volunteers
- 455 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse
A Randomized Controlled Trail of Uterosacral Ligament Suspension in the Treatment of Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is one of the common benign gynecological disorders in middle-aged and elderly women, which severely affects patients' quality of life and increases the social burden.
- Trial name
- NCT06418438
- Testing
- Laparoscopic uterosacral ligament suspension with hysterectomy, Laparoscopic uterosacral ligament suspension with cervical amputation
- Volunteers
- 314 people
- Sponsor
- Lan Zhu
Pelvic Organ Prolapse
Validation of Transvaginal Tactile Imaging
The purpose of this study is to validate safety and effectiveness in assessment of the female pelvic floor tissue, and, assess the ability of Vaginal Tactile Imager (VTI) to detect early prolapse conditions and characterize the…
- Trial name
- VTI-03 (NCT01491334)
- Where
- 2 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Artann Laboratories