Clinical trials: Pelvis
Tissue Adhesion, Gynecologic Surgery
The Assessment of the Use of Anti-Adhesion Agents to Prevent Pelvic Postoperative Adhesions
The aim of this study is to assess the safety and effectiveness of PROTAHERE Absorbable Adhesion Barrier to prevent pelvic postoperative adhesions.
- Trial name
- NCT04063085
- Testing
- PROTAHERE Absorbable Adhesion Barrier, Hyalobarrier Gel, No treatment
- Where
- Taiwan
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Colonic Inertia, Dyschezia
Investigation of the Effect of Manual Therapy and Pelvic Floor Exercises on Pelvic Floor Muscles
The goal of this clinical trial is to Investigation of the effect of manual therapy and pelvic floor exercises on pelvic floor muscle in women with constipation.
- Conditions
- Colonic Inertia, Dyschezia, Constipation
- Trial name
- NCT06494917
- Testing
- pelvic floor exercises, Pelvic floor exercises and manual therapy techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Endometriosis, Endometriosis-related Pain
Relugolix for Endometriosis Associated Pain
Endometriosis is a chronic, estrogen-dependent condition frequently associated with pelvic pain and reduced quality of life. Relugolix combination therapy (CT), an oral GnRH receptor antagonist-based treatment, has demonstrated…
- Conditions
- Endometriosis, Endometriosis-related Pain, Pelvic Pain Syndrome
- Trial name
- RELAX (NCT07440043)
- Testing
- Patients with a diagnosis of endometriosis receiving treatment with Relugolix CT, according to clinical practice,
- Volunteers
- 33 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Female Infertility, Female Infertility Due to Ovulatory Disorder
Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility
The study will describe the effectiveness of ovarian stimulation in correlation with female infertility causes in a Lebanese population: a comparative study using 5 protocols of ovulation induction (treatment with "A"…
- Conditions
- Female Infertility, Female Infertility Due to Ovulatory Disorder, Premature Ovarian Failure, Polycystic Ovary Syndrome
- Trial name
- CS-EOSP-ICSI (NCT04071574)
- Testing
- Human Chorionic Gonadotropin (hCG), Gonadotropins, GNRH-A Triptorelin
- Where
- Lebanon
- Volunteers
- 200 people
- Sponsor
- Lebanese University
Urinary Incontinence,Stress
Sonographic Evaluation of the Single-incision Needleless (Contasure-needleless®) Mini-sling Placement to Predict Success
Transperineal ultrasonography is gaining importance in preoperative and postoperative evaluation of the patient with urinary incontinence with allowing well detailed information about the anterior compartment.
- Trial name
- NCT03763097
- Testing
- Pelvic floor ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bartin State Hospital
Piriformis Syndrome
Comparative Effects of Stecco-fascial Manipulation and Rolfing Structural Integration in Patients With Piriformis Syndrome
This study aims to compare the effectiveness of Stecco Fascial Manipulation and Rolfing Structural Integration in treating Piriformis syndrome, focusing on special outcomes like pain severity and functional outcomes.
- Trial name
- Piriformis (NCT07322185)
- Testing
- Experimental: GROUP A ( Stecco fascial Manipulation), Experimental: GROUP B (Rolfing Structural Integration)
- Where
- 3 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Danyal Ahmad
Obstetric; Injury Pelvic Floor
Perineal Massage During Labor for the Prevention of Perineal Trauma
The purpose of this study is to evaluate whether perineal massage during labor can help prevent perineal trauma, such as lacerations or episiotomies.
- Trial name
- NCT07099690
- Testing
- Perineal massage
- Where
- Brazil
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Pelvic Organ Prolapse
VESPER: Pelvic Organ Prolapse Study
Patients seen with Stage 1-2 pelvic organ prolapse (POP) who have failed conservative treatments will be offered to participate in a sham controlled RCT of outpatient therapy with the Fotona Smooth Erbium Yag Laser.
- Trial name
- VESPER:POP (NCT03995797)
- Testing
- Laser therapy
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Pelvic Organ Prolapse
A Feasibility Study on the Value of Pelvic Floor Training After Pelvic Organ Prolapse Surgery
The main objective is to assess the feasibility of a randomized controlled trial that investigates the effects of pelvic floor training on recurrence in pelvic organ prolapse surgeries.
- Trial name
- NCT04539782
- Testing
- Physiotherapy intervention
- Where
- Iceland
- Volunteers
- 50 people
- Sponsor
- Landspitali University Hospital
Pelvic Pain
Oral Gabapentin in Management of Chronic Pelvic Pain in Females: A Randomised Placebo-controlled Study.
Aim :The aim of this study is to evaluate the efficacy of oral Gabapentin in the treatment of chronic pelvic pain in females. The study is designed as a randomised, placebo-controlled, clinical trial.32 patients will be enrolled…
- Trial name
- NCT02918760
- Testing
- Gabapentin
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sexuality, Sexual Dysfunction
Improving Female Sexual Wellness
The purpose of this study is to assess the effect of commercially available genital vibrator use on sexual health, female pelvic floor disorders, and overall quality of life among a diverse population of women.
- Conditions
- Sexuality, Sexual Dysfunction, Sexual Desire Disorder, Hypoactive Sexual Desire Disorder
- Trial name
- NCT04824820
- Testing
- Vibrator
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Cedars-Sinai Medical Center
Urothelial Carcinoma
A Phase I/II Trial of AEZS-108 in Urothelial Cancer Patients Who Failed Platinum-chemotherapy
The purpose of this study is to determine the appropriate dose of AEZS-108 to treat patients with a tumor of the urinary system.
- Trial name
- NCT01234519
- Testing
- AEZS-108, AEZS-108 at MTD
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- AEterna Zentaris
Colorectal Cancer
Radiation Therapy on Pelvic Floor Disorders in Women
Investigators propose a retrospective cohort study to examine the impact of radiation therapy on the global pelvic floor function of women who have completed the immediate surveillance period for colorectal cancer
- Trial name
- RadPFD (NCT04623515)
- Testing
- REDCap Questionnaires
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Prostate Cancer
Radiotherapy of the Prostate and the Pelvic Lymph Nodes After Neoadjuvant Antihormonal Treatment
For patients with prostate cancer and a high risk of lymph node involvement or confirmed pelvic lymph node metastases, radiotherapy of the whole pelvis is a treatment option.
- Trial name
- PLATIN (NCT01903408)
- Testing
- Intensity-modulated radiotherapy of the pelvic lymph nodes using SIB
- Where
- Germany
- Volunteers
- 199 people
- Sponsor
- Heidelberg University
Pelvic Organ Prolapse
Gabapentin Reduces Opioid Use Postoperatively ("GROUP Study")
Gabapentin is a medication used primarily to treat seizures and pain. Studies have shown that this medication can help reduce pain after surgery, including hysterectomy, where the uterus or "womb" is removed.
- Trial name
- GROUP (NCT02999724)
- Testing
- Gabapentin
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Mount Sinai Hospital, Canada
Interstitial Cystitis, Pelvic Pain
Intravesical Liposomes for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS)
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a poorly understood chronic disorder of unknown etiology consisting of irritative bladder symptoms and pelvic pain that dramatically affects quality of life.
- Trial name
- NCT01731470
- Testing
- Liposomes
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Kenneth Peters, MD
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Interstitial Cystitis, Bladder Pain Syndrome
Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work.
- Conditions
- Chronic Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Cystitis, Interstitial
- Trial name
- NCT06299683
- Testing
- Psychosocial Treatment, Pelvic Floor Physical Therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Vanderbilt University Medical Center
Prolapse; Female
Barbed-suture Efficiency Study for Sacrocolpopexy
Minimally invasive sacrocolpopexy (SCP) performed laparoscopically or with robotic assistance is associated with improved patient-centered outcomes such as faster recovery times, less pain, less bleeding, and shorter hospital…
- Trial name
- BEST (NCT05760794)
- Testing
- Non-barbed delayed absorbable suture, Barbed delayed absorbable suture
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Wake Forest University Health Sciences
Ovarian Neoplasm
Prediction of Ovarian Malignancy in the Presence of Sonographic Pelvic Mass
The objective of the study is to create a test that will discriminate between malignant and benign ovarian mass that was diagnosed by ultrasound.
- Trial name
- NCT01477788
- Where
- Israel
- Sponsor
- HaEmek Medical Center, Israel