Clinical trials: Penetrating Injury
Eye Trauma
Treatment of Corneal Wounds Emergencies During the COVID-19 Shutdown: Absorbable 10-0 Vicryl Sutures as a Valuable Strategy.
Vicryl (polyglactin) 10-0 resorbable suture is rarely used, little known to ophthalmologists but may offer therapeutic and practical advantages in eligible cases of corneal trauma, particularly during a COVID-19 pandemic.
- Trial name
- NCT04733846
- Testing
- data collection
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Full-thickness Skin Defects, Degloving Injuries
RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction
A prospective randomized within-subject controlled study to compare the clinical performance of conventional autografting with and without the RECELL system on acute non-burn full-thickness skin defects.
- Conditions
- Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin
- Trial name
- NCT04091672
- Testing
- Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
- Where
- 18 sites in United States
- Volunteers
- 65 people
- Sponsor
- Avita Medical
Blunt Trauma, Penetrating Wound
Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma
Primary Aim: To determine the feasibility and safety of hypotensive resuscitation for the early treatment of patients with traumatic shock compared to standard fluid resuscitation.
- Conditions
- Blunt Trauma, Penetrating Wound, Hemorrhagic Shock
- Trial name
- HypoResus (NCT01411852)
- Testing
- 0.9% Sodium Chloride 250 mL bolus, 0.9% Sodium Chloride 2000 mL bolus
- Where
- 6 sites in United States, Canada
- Volunteers
- 192 people
- Sponsor
- University of Washington
Needlestick Injuries
Sharp Risks in a Time of Crisis: Needle-Stick Injuries in Eastern Sudan Healthcare
Background: Needle-stick injuries (NSIs) expose healthcare providers to serious bloodborne infections such as HBV, HCV, and HIV.
- Trial name
- NCT07143422
- Volunteers
- 272 people
- Sponsor
- National Center for Gastroentestinal and Liver Disease
Wounds and Injuries, War-Related Injuries
Retrospective Morbidity and Mortality Study of Conflict-Related Injuries: Erbil, Iraq
A retrospective morbidity and mortality study, using routinely collected data, investigating the epidemiology of patients with conflict-related injuries presenting to a dedicated trauma hospital in Erbil, Iraq, during the…
- Conditions
- Wounds and Injuries, War-Related Injuries, Gunshot Wound, Blast Injuries
- Trial name
- NCT03358758
- Where
- Sweden
- Volunteers
- 1,832 people
- Sponsor
- Karolinska Institutet
Evaluate Laparoscopic Management in Patients With Penetrating Anterior Abdominal Wall Trauma
Role of Laparoscopy in Penetrating Anterior Abdominal Wall Injuries
The current study is aiming to evaluate the diagnostic and therapeutic role of laparoscopy in patients with penetrating anterior abdominal wall trauma as regard the accuracy of diagnosis and efficacy in management and avoidance…
- Trial name
- NCT05826262
- Testing
- diagnostic laparoscopy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Chronic Pain, Psychological Disorders
Influence of Psychological Status on the Results of Pain Treatment in Patients With Gunshot and Mine-explosive Wounds
82.1% of patients with gunshot and mine-explosive wounds and wounds during hostilities in Ukraine have negative results of pain treatment, which leads to its chronicity.
- Trial name
- IPSRPTPGaM-EW (NCT05478642)
- Testing
- The Hospital Anxiety and Depression Scale.
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Chronic Pain
The Influence of Therapeutic Tactics of Analgesia on the Long-term Results of Pain Treatment in Patients With Gunshot and Mine-explosive Wounds
Considering that in 82.1% of cases it is not possible to achieve a positive result of treatment, the data of our study will play an important role in the treatment of such patients.
- Trial name
- ITTAL-TRPT (NCT05485116)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Myocardial Infarction
Acute Myocardial Infarction by Penetrating Cardiac Trauma
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly…
- Trial name
- NCT01182064
- Where
- Colombia
- Volunteers
- 51 people
- Sponsor
- Universidad de Antioquia
Head Trauma, Craniocerebral Injuries
Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas
The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the a portable near-infrared-based device (portable NIR-based device), the InfraScanner 2000™, to detect…
- Conditions
- Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries
- Trial name
- NCT04505293
- Testing
- InfraScanner 2000™
- Where
- 2 sites in United States, Uganda
- Volunteers
- 672 people
- Sponsor
- Duke University
Penetrating Injury Neck
Tree Branch Penetrating Injury
Penetrating trauma to the neck can result in severe morbidity and mortality. Location of the injury dictates the appropriate clinical management. Challenging traumatic injuries require resourceful treatment options
- Trial name
- NCT05569447
- Testing
- Balloon Tamponade
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- South Texas Health System McAllen
Penetrating Abdominal Trauma
Outcomes After Laparotomy for Penetrating Abdominal Trauma
The purpose of this study is to evaluate outcomes of adult patients hospitalised due to penetrating abdominal trauma at a tertiary trauma hospital in South Africa.
- Trial name
- NCT04536818
- Testing
- Laparotomy
- Where
- South Africa
- Volunteers
- 196 people
- Sponsor
- Karolinska Institutet
Penetrating Trauma Registry and Open Source Data
Penetrating Trauma Registry and Open Source Data
Penetrating injuries comprise roughly 30% of Methodist Health System (MHS) trauma patients. Firearm-related events have become more prevalent in the past few years.
- Trial name
- NCT06136273
- Testing
- Treatment measures and intervention strategies
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Methodist Health System
Hemothorax, Pneumothorax
Negative Pleural Suction for Tube Thoracostomy in Patients With Chest Trauma
The purpose of this study is to determine whether the use of negative pleural suction in tube thoracostomy is more effective than water seal alone for the treatment of pneumothorax and/or hemothorax in patients with chest trauma.
- Conditions
- Hemothorax, Pneumothorax, Hemopneumothorax, Chest Injury Trauma Blunt
- Trial name
- NCT01864577
- Testing
- Negative Pleural Suction at -20 cm H2O, Water seal
- Where
- Colombia
- Volunteers
- 110 people
- Sponsor
- Universidad de Antioquia
Corneal Foreign Body Following Blast Injury
Visual Prognosis in Non-Penetrating Corneal Blast Injuries
The purpose of this study is to assess visual quality of patients with non-penetrating, non-metallic, stable corneal foreign bodies.
- Trial name
- NCT00414219
- Testing
- Visual quality of patients with corneal eye injuries
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Trauma
Penetrating Gunshot Injuries at a Single Johannesburg Centre
A retrospective audit of cardiac penetrating cardiac injuries with specific reference to GSW
- Trial name
- NCT05016986
- Testing
- Standard clinical management
- Where
- 2 sites in South Africa
- Volunteers
- 40 people
- Sponsor
- University of Witwatersrand, South Africa
Open Abdomen, Abdominal Adhesions
Seprafilm in Open Abdomens: a Study of Wound and Adhesion Characteristics in Trauma Damage Control Patients
The goal of this study is to test the effects of Seprafilm adhesion barrier on patients who are undergoing open abdomen damage control management for traumatic injuries when compared to no adhesion barrier use.
- Conditions
- Open Abdomen, Abdominal Adhesions, Trauma, Wounds and Injury
- Trial name
- OASIT (NCT01594385)
- Testing
- Seprafilm
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stan Stawicki
Head Injuries, Penetrating, Head Injuries, Closed
Concordance Between Ultra-low Dose (ULD) and Standard Dose CT Scans in the Search for Traumatic Brain Injury
The aim of this research is to evaluate the diagnostic concordance of ultra low-dose and standard dose reconstructed computed tomography acquisitions using the ADMIRE algorithm to search for intracranial lesions - both…
- Trial name
- ULD-CRANE (NCT04939688)
- Testing
- Conventional dose AND ultra low-dose CT scanning in the search for cranial lesions
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Pancreatic Trauma, Pancreatic Duct Injury
A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes
The goal of this observational study is to compare the presentation, treatment, and outcomes in patients suffering traumatic pancreatic injuries from blunt or penetrating trauma. The questions this study aims to answer are: 1.
- Conditions
- Pancreatic Trauma, Pancreatic Duct Injury, Pancreas Necrosis, Pancreas Cyst
- Trial name
- NCT06227871
- Testing
- Exploratory laparotomy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Kern Medical Center