Clinical trials: Penile Diseases
Paget Disease, Extramammary, Rhabdomyosarcoma
Multi-cohort, Single-arm Phase II Study of Albumin-paclitaxel, Ifosfamide, and Cisplatin in the Treatment of Rare Advanced Tumors
The goal of this clinical trial is to learn if albumin-paclitaxel, ifosfamide and cisplatin (Nab-TIP) works to treat advanced rare tumors including PAGET's disease of scrotum with infiltrating sweat gland carcinoma （cohort 1）…
- Conditions
- Paget Disease, Extramammary, Rhabdomyosarcoma, Testicular Cancer, Penile Cancer
- Trial name
- NCT06684327
- Testing
- Albumin-paclitaxel Injection
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Adenocarcinoma, Adenocystic Carcinoma
The Registry of Oncology Outcomes Associated With Testing and Treatment
This study is to collect and validate regulatory-grade real-world data (RWD) in oncology using the novel, Master Observational Trial construct. This data can be then used in real-world evidence (RWE) generation.
- Conditions
- Adenocarcinoma, Adenocystic Carcinoma, Anal Cancer, Appendix Cancer
- Trial name
- ROOT (NCT04028479)
- Testing
- Biomarker Testing (L), Systemic Treatment (T), Patient Reported Outcomes (P)
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Taproot Health
Peyronie Disease
Peyronie Disease Questionnaire (PDQ): Turkish Validation
The purpose of the present study is to translate into the Turkish and a perform a validation of the Turkish version of a PDQ and to ensure the use of Turkish validation of the PDQ in clinical use and studies.
- Trial name
- Turkish PDQ (NCT06621420)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Peyronie Disease
Pelvic CT with Agatston Calcium Score for Peyronie Disease
The purpose of this study is to find out how including a CT exam of the penis can help urologists make treatment decisions for patients with calcified Peyronie's disease.
- Trial name
- NCT05480683
- Testing
- CT exam
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Peyronie Disease
French Translation and Validation of the PEYronie's Disease QUESTionnaire
This study is a prospective cohort dedicated to peyronie's disease. The aim is to validate the french translation of the peyronie's disease questionnaire. The primary endpoint is the response rate to the questionnaire.
- Trial name
- FRAPEYQUEST (NCT05768867)
- Testing
- FRAnçaise du PEYronie's Disease QUESTionnaire
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Penile Induration, Penile Diseases
Stem Cell Treatment of Peyronie´s Disease.
Purpose of the project is to investigate if a single injection of autologous stromal vascular fraction into and around plaque is a safe and suitable treatment.
- Trial name
- NCT04771442
- Testing
- Stromal vascular fraction
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Peyronie Disease, Penile Diseases
Safety and Efficacy of Low-intensity Shockwave Therapy for Peyronie's Disease
Investigation of the effect of Low-intensity extracorporeal shockwave therapy (ESWT) for Peyronie's disease (PD) via a single blind, sham-controlled, randomized clinical trial.
- Trial name
- ONDELA (NCT04821115)
- Testing
- Low intensity choc waves therapy (active applicator)
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Hopital Foch
Peyronies Disease
Fractionated Carbon Dioxide Laser Therapy for Treatment of Peyronie's Disease
This is a pilot study that evaluates the use of Fractional Carbon Dioxide Laser Therapy in the treatment of Peyronie's Disease. Study participants will be assigned to receive Fractional Carbon Dioxide Laser Therapy at 10-15%…
- Trial name
- NCT04326465
- Testing
- Fractional Carbon Dioxide Laser Therapy at 10-15% Laser Density Coverage
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Peyronie Disease
Non-ablative Radiofrequency and Low Intensity Shock Wave Therapy in Fibrotic Plaque in Men With Peyronie's Disease
The goal of this one arm clinical trial is to evaluate the safety and describe the clinical response of non-ablative radiofrequency treatment associated with shockwave therapy in men with Peyronie's disease.
- Trial name
- NCT06303661
- Testing
- Non-ablative Radiofrequency, Low-intensity Shock Wave Therapy
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Centro de Atenção ao Assoalho Pélvico
Peyronie's Disease
Real-World Data Study to Understand Effectiveness of Treatments in Peyronie's Disease
This is an observational study, meaning participants will not receive any investigational treatment as part of this study. Researchers will collect real-world data (RWD) to gain a more in-depth knowledge of the treatment of…
- Trial name
- CURVE-PD (NCT05873595)
- Where
- 7 sites in United States
- Volunteers
- 29 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie's Disease
H-22411: BOTOX® for Peyronie's Disease
Peyronie's disease is a condition in which a plaque, or hard lump, forms on the penis. It causes hardened tissue, pain, and an abnormal bending in the penis. These symptoms are more severe during an erection.
- Trial name
- NCT00812838
- Testing
- 100 units of Botulinum Toxin Type A, Preservative free normal saline, 100 units Botulinum Toxin A
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mohit Khera
Peyronie Disease, Penile Curvature
Focused Shock Wave Therapy Outcomes in Peyronie's Disease and Erectile Dysfunction
The purpose of this research is to determine the pure or additional effects of penile shockwave therapy with low intensity linear shock wave machine for penile curvature (and/or erectile dysfunction) vs patients' undergoing other…
- Conditions
- Peyronie Disease, Penile Curvature, Erectile Dysfunction
- Trial name
- NCT05646602
- Testing
- Collagenase Clostridium Histolyticum, Duolith SD1 T-TOP
- Where
- United States
- Sponsor
- Mayo Clinic
Peyronie's Disease, Hyaluronic Acid
Intralesional Hyaluronic Acid and Verapamil Injection in Peyronie's Disease
The aim of the present study is to investigate whether intralesional injections of Hyaluronic acid in the acute phase could reduce the progression of Peyronie's disease thanks to its interference with inflammatory and…
- Conditions
- Peyronie's Disease, Hyaluronic Acid, Verapamil
- Trial name
- NCT05855070
- Testing
- Intralesional treatment with Hyaluronic acid, Intralesional treatment with Verapamil
- Volunteers
- 42 people
- Sponsor
- Benha University
Diabetes Mellitus, Type 2, Penile Diseases
Penile Length Restoration in Men With Diabetes Mellitus, Type II
The objective of the current study is to evaluate the efficacy of a novel penile traction device in restoring lost penile length in men with type 2 diabetes.
- Trial name
- NCT03756688
- Testing
- RestoreX PTT - 6 months, RestoreX PTT - 3 months
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Mayo Clinic
Hydrocele, Spermatocele
Evaluating Patient Tolerability and Success for Penile and Scrotal Urologic Procedures Under Conscious Sedation: A Prospective Study
The goal of this observational study is to evaluate patient reported outcomes and tolerability of scrotal and penile urologic procedures under the administration of minimal conscious sedation.
- Conditions
- Hydrocele, Spermatocele, Varicocele, Epididymal Cyst
- Trial name
- NCT05617261
- Testing
- Conscious sedation
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Manitoba
Peyronie Disease
Novel Nanofat Regenerative Surgical Technique for Peyronies' Disease Treatment
Peyronies' disease (PD) is an acquired connective tissue disorder characterized with the growth of fibrous and/or calcified plaques in the tunica albuginea of the penis.
- Trial name
- IPPNANOFAT (NCT05316714)
- Testing
- Nanofat grafing
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Roma La Sapienza
Prostate Cancer, Penile Diseases
Penile Length Maintenance Post-Prostatectomy
The objective of the current study is to evaluate the efficacy of a novel, class I (ie. lowest risk, clinical studies not required) medical penile traction device in preventing loss of penile length in men undergoing…
- Trial name
- NCT03500419
- Testing
- RestoreX, No treatment
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Mayo Clinic
Peyronie Disease
Treatment Response to Xiaflex for Men With Peyronie's Disease
The purpose of this research study is to develop a database of patients with Peyronie's disease who are treated at the University of Miami.
- Trial name
- NCT03774264
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
Skin Diseases, Penile Diseases
Rare Benign Lesion of Peins
PEKMB was first named and described by Lortat-Jacob \& Civatte in 1961 and by Bart \& Kopf later. This rare condition is mostly reported in elderly males. The keratotic scales is usually micaceous and resembles psoriasis.
- Trial name
- NCT04725292
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Assiut University
Peyronie's Disease (PD)
Xiaflex® Plus Testosterone Treatment Pilot Study Protocol
In this open-label, six-month, pilot study of men with Peyronie's disease there will be one subject group consisting of 20 subjects. All subjects will receive Xiaflex® plus testosterone (T) treatment (Aveed®).
- Trial name
- NCT03815331
- Testing
- Xiaflex®, Aveed
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Men's Health Boston