Clinical trials: Penile Diseases
Penile Hypospadias
Does Graft Improves the Outcome TIP Repair for Primary Distal Hypospadias?
Hypospadias is a common congenital anomalies in male children affecting 1 in 200-300 male births, the penis urethral opening is found ventrally, penile curvature and a lack of foreskin (1).
- Trial name
- NCT05528276
- Testing
- Repair surgery
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Assiut University
Hypospadias and Epispadias
Comparison of Pudendal Nerve Block and Caudal Block for Hypospadias in Young Children
The purpose of this randomized blinded prospective study is to compare the analgesic efficacy and duration of a Pudendal Nerve Block (PNB) to a Caudal Block (CB) for pediatric patients, ages 6 months to 2 years, undergoing…
- Trial name
- NCT03145415
- Testing
- Caudal block, Bilateral Pudendal block
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Hypospadias
Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair
The primary objective of this study is to determine the efficacy of administering a course of postoperative oral steroids in pediatric patients undergoing proximal hypospadias repair as prevention against complications.
- Trial name
- NCT02162810
- Testing
- Prednisolone
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Francis Schneck
Postoperative Pain
Pudendal vs Caudal Block for Pediatric Penile Surgery
The study will compare recovery profile in children receiving pudendal blocks vs caudal analgesia for ambulatory circumcision or hypospadias repair in children between 6 months and 2 years.
- Trial name
- NCT04840654
- Testing
- Caudal Block, Pudendal Block
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Chicago
Peyronie's Disease
Study of AA4500 in the Treatment of Peyronie's Disease
This study is a Phase 3, double-blind, randomized, placebo-controlled study of the safety and efficacy of AA4500 0.58 mg in subjects with Peyronie's disease. Approximately 300 (200 AA4500 and 100 placebo) men will be randomized.
- Trial name
- NCT01221623
- Testing
- AA4500
- Where
- 34 sites in United States, Australia
- Volunteers
- 418 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Male Sexual Dysfunction, Spinal Cord Injury
Predictive Factors for Male Sexual Dysfunction After Traumatic Spinal Cord Injury
Objective: To analyze the association between sexual function of men with spinal cord injury with possible predictive factors for dysfunction.
- Trial name
- NCT02860689
- Testing
- using questionnaires - International Index Erectile Function
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade Federal de Pernambuco
Penile Cancer
A PHASE II, RANDOMIZED STUDY TO ASSESS MAINTENANCE THERAPY WITH CEMIPLIMAB VERSUS BEST SUPPORTIVE CARE AFTER 1ST LINE PLATINUM-BASED CHEMOTHERAPY IN ADVANCED/RECURRENT PENILE CANCER
This is a phase II, randomized study which will enroll participants given 4 to 6 cycles of first-line platinum-based chemotherapy treatment for advanced penile SCC not amenable by curative surgical treatment (stages III-IV as per…
- Trial name
- BRAVA PENILE (NCT07101822)
- Testing
- Cemiplimab
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Hospital Israelita Albert Einstein
Priapism
ManAgement of pRiapiSm and Its Impact on Outcomes
Priapism is a urological emergency that is defined as a prolonged penile erection lasting more than 4 h, remaining despite orgasm and in the absence of sexual stimulation.
- Trial name
- MARS (NCT04932902)
- Where
- 5 sites in Italy, Portugal
- Volunteers
- 200 people
- Sponsor
- Policlinic Hospital "G. Rodolico"
Hypogonadism, Erectile Dysfunction
Testosterone for Penile Rehabilitation After Radical Prostatectomy
The purpose of this study is to determine the effectiveness of testosterone replacement therapy (TRT) in men following surgery to remove the prostate in improving erectile function.
- Trial name
- NCT00848497
- Testing
- Testim®, Viagra®
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mohit Khera
Penile Cancer
The Role of Functional Magnetic Resonance Imaging in Preoperative Assessment of Primary Penile Carcinoma
The proposed project is intended as a prospective study that includes 60 patients with newly diagnosed penile squamous cell carcinoma (SCC) referred to Oslo University Hospital (OUH), Radiumhospitalet, for surgery, primarily…
- Trial name
- NCT05447273
- Testing
- Multi-parametric, functional magnetic resonance imaging (MRI)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Erectile Dysfunction, Hyperbaric Oxygen Therapy
HBOT Application in Erectile Dysfunction
Recent studies have shown that hyperbaric oxygen therapy (HBOT) can induce angiogenesis and improve impaired organ function. HBOT was also recently suggested as a possible therapy for ED due to surgical injuries.
- Trial name
- HBOTED (NCT02619383)
- Testing
- Hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 37 people
- Sponsor
- Assaf-Harofeh Medical Center
Erectile Dysfunction
Evaluation of the Coloplast Titan® IPP for Maintaining Penile Length While Treating Erectile Dysfunction (ED)
This study is designed to assess the effectiveness of the Coloplast Titan® Inflatable Penile Prosthesis (IPP) at maintaining or increasing penile length after implantation of the device.
- Trial name
- NCT00731666
- Testing
- Inflatable Penile Prosthesis
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Coloplast A/S