Clinical trials: Penile Hypospadias
Postoperative Analgesia, S-ketamine
Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias
Caudal analgesia with ropivacaine is commonly used in sub-umbilical pediatric surgery. However, increasing the dosage of ropivacaine has not been found to prolong the action significantly while complications will be serious.
- Conditions
- Postoperative Analgesia, S-ketamine, Pediatrics, Caudal Block
- Trial name
- NCT05922605
- Testing
- S-ketamine & Ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Tao Zhang
Hypospadias Repair
TIP Repair of Distal Penile Hypospadias Using Rapidly Absorbable Braided Vs Slowly Absorbable Monofilament Sutures
Objective: To study the effect of tubularizing the urethral plate in DPH in children using 2 different absorbable suture materials, rapidly absorbable, braided 6/0 Vicryl and slowly absorbable monofilament 6/0 Polydioxanone, on…
- Trial name
- NCT06413901
- Testing
- TIP
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Cairo University
Hypospadias
Local Oestrogen Versus Placebo as Preoperative Treatment in Patients With Severe Hypospadias: Effects on Post-operative Complications
Hypospadias is a congenital abnormality of the penis that is caused by incomplete development of the anterior urethra. This pathology is one of the most common genital anomalies in paediatric urology .The incidence is reported to…
- Trial name
- HYPOSPADES (NCT01370798)
- Testing
- promestriene, Urethroplasty, Wrist X ray
- Where
- 4 sites in France
- Volunteers
- 244 people
- Sponsor
- Hospices Civils de Lyon
Tonsillar Hypertrophy, Adenoid Hypertrophy
Interactive Perioperative Teaching Platform (IPTP)
The proposed study will assess whether an interactive perioperative teaching platform (IPTP) provided to families of patients undergoing ambulatory pediatric surgery will reduce families' anxiety, and improve satisfaction and…
- Conditions
- Tonsillar Hypertrophy, Adenoid Hypertrophy, Cryptorchidism, Hypospadias
- Trial name
- NCT03677453
- Testing
- Interactive Perioperative Teaching Platform
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Vidya Raman
Hypospadias, Undescended Testis
Visual Guidelines and Tutoring in Pediatric Urological Surgery
The aim of this study is checking impact of visual guidelines (picture book) and tutoring in pediatric urologic surgery
- Conditions
- Hypospadias, Undescended Testis, Hydrocele, Ureteropelvic Junction Stenosis
- Trial name
- NCT02040389
- Testing
- Picture book, Standard preoperative education
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Shaare Zedek Medical Center
Hypospadias
Modified Second Layer Repair for Distal Penile Hypospadias
to evaluate a modification to snodgrass technique in second layer closure of distal penile hypospadias
- Trial name
- NCT05253456
- Testing
- Derma -Dartos Flap for second layer closure
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Ain Shams University
Perioperative Bleeding During Recurrent Hypospadias Repair
Evaluating the Efficacy and Safety of Tranexamic Acid in Reducing Perioperative Bleeding During Recurrent Hypospadias Repair.
This study aims to fill that gap by evaluating the efficacy and safety of intravenous TXA in children undergoing redo hypospadias surgery, potentially establishing a new standard of care
- Trial name
- NCT07778992
- Testing
- single intravenous (IV) bolus dose of tranexamic acid (TXA) at 15 mg/kg (maximum dose 1000 mg), Control (Normal saline)
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Aswan University Hospital
Hypospadias
The Role of "Hypospadias Objective Scoring Evaluation" (HOSE) and Uroflowmetry in Evaluation of Successful Hypospadias Repair
Hypospadias is a common anomaly of the male genitalia affecting 0.4-8.2 of 1000 live male babies and varies considerably in severity.
- Trial name
- NCT05032222
- Testing
- Uroflowmetry
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Mohammad Alaa Ezzat
Hypospadias, Caudal Block
Ultrasound Guided Sacral Erector Spinae Plane Block Versus Ultrasound Guided Caudal Block in Pediatric Undergoing Hypospadias Surgery
Randomized, parallel-group, assessor-blinded clinical trial at Tanta University Hospitals comparing ultrasound-guided sacral erector spinae plane block (sESPB) versus ultrasound-guided caudal epidural block for postoperative…
- Conditions
- Hypospadias, Caudal Block, Erector Spinae Plane Block, Pain, Postoperative
- Trial name
- NCT07099560
- Testing
- Ultrasound-guided sacral erector spinae plane block (sESPB), Ultrasound-guided caudal epidural block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Hypospadias
Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair
The primary objective of this study is to determine the efficacy of administering a course of postoperative oral steroids in pediatric patients undergoing proximal hypospadias repair as prevention against complications.
- Trial name
- NCT02162810
- Testing
- Prednisolone
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Francis Schneck
Caudal Block
Methylprednisolone Versus Dexamethasone in Pediatric Caudal Block
This randomized, double-blind, controlled bi-center study was designed to compare the postoperative analgesic efficacy of dexamethasone and methylprednisolone in caudal block for children undergoing hypospadias surgical repair…
- Trial name
- NCT05717374
- Testing
- caudal block using dexamethasone, caudal block using methylprednisolone
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Hypospadias, Distal Penile Hypospadias (Disorder)
Effect of Adding Byar's Flap to Double Dartos Coverage in TIP Urethroplasty for Distal Hypospadias: A Randomized Trial
This randomized controlled trial evaluates the effect of adding Byar's flap in combination with double dartos flap coverage during tubularized incised plate (TIP) urethroplasty in children with distal hypospadias.
- Trial name
- DD-TIP-BF (NCT07525570)
- Testing
- Double Dartos Flap Coverage, Byar's Flap + Double Dartos Flap
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Javaid Afridi
Hypospadias
Isoamyl 2-Cyanoacrylate in the Urethro-cutaneous Fistula Repair
cyanoacrylate has an impact that may aid in the successful repair of urethra-cutaneous fistula (UCF) that occur after hypospadias surgical repair
- Trial name
- NCT04876976
- Testing
- Cyanoacrylate, Isobutyl, Classic surgical repair
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Hypospadias
Efficacy of Fibrin Sealant in Hypospadias Surgery
The aim of the study was to evaluate if application of a fibrin sealant over the urethroplasty suture line for waterproofing instead of a dartos vascularized pedicled flap to reduce complications and improve the outcome in…
- Trial name
- NCT05666206
- Testing
- fibrin sealant in hypospadias
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Postoperative Pain
Effect of Caudal Nalbuphine on Postoperative Analgesia in Children
Nalbuphine as an adjuvant to bupivacaine caudal anesthesia for postoperative analgesia in children undergoing Hypospadias repair. 2 groups, 30 patients each
- Trial name
- NCT02618876
- Testing
- Nalbuphine plus Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypospadias
Effect of Caudal and Penile Block on Hypospadias Repair Complications
Hypospadias is one of the most common genitourinary (GU) malformations, seen in approximately 1 of 250 male live births. Common methods of local anesthesia administration for hypospadias surgery include caudal and dorsal penile…
- Trial name
- NCT02851290
- Testing
- Caudal block anesthesia, Dorsal penile nerve block anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Baylor College of Medicine
Hypospadias, Postoperative Pain
Caudal Epidural Block and DPNB in Hypospadias
Hypospadias, seen in every 200-300 births, is one of the most common congenital anomalies of the penis and is defined as the urethral meatus being located in the ventral part of the penis instead of its normal place.
- Trial name
- NCT04215874
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Regional Anesthesia, Hypospadias
Ultrasound-guided PNB and DPNB for Pediatric Distal Hypospadias Surgery
Hypospadias repair is a urological surgical operation that is very painful in the postoperative period and requires long-term analgesia.
- Trial name
- NCT04668183
- Testing
- Pudendal nerve block group, Dorsal penile nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Postoperative Pain
Perfusion Index in Assessment of Postoperative Pain in Children.
The aim of this study will be to examine the validity of perfusion index in predicting pain and evaluation of its severity in the postoperative period.
- Trial name
- NCT06245239
- Testing
- perfusion index
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Assiut University