Clinical trials: Penile Hypospadias
Disorder of Sex Development, Intersex Conditions
Decision Support for Parents Receiving Information About Child's Rare Disease
The birth of a child with a disorder of sex development (DSD) is stressful for parents and members of the healthcare team. The "right" decisions about gender assignment (is it a boy? a girl?) and the best course of action (e.g.…
- Conditions
- Disorder of Sex Development, Intersex Conditions, Congenital Adrenal Hyperplasia, Hypospadias
- Trial name
- DSD DST (NCT01875640)
- Where
- 4 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hypospadias
Influence of Pesticide Exposure on the Occurrence of Hypospadias in Newborns in Picardie
We want to see if there is a relationship between exposure to pesticides and the occurrence of hypospade in Picard newborn .
- Trial name
- HYPOMECO (NCT02805491)
- Testing
- meconium, self questionnaires to parents
- Where
- 11 sites in France
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hypospadias, Hypospadias and Epispadias and Other Penile Anomalies
Efficacy of Amniotic Membranes in Complex Genitourinary Reconstruction
Urinary fistulas are unfortunately one of the most common post operative complications in hypospadias repairs and bladder neck transections on pediatric and adult populations, an estimated 20%, resulting in multiple repeat…
- Conditions
- Hypospadias, Hypospadias and Epispadias and Other Penile Anomalies, Fistula, Fistula, Urinary
- Trial name
- NCT03685955
- Testing
- Amniotic membranes
- Sponsor
- Johns Hopkins University
Elective Penile Surgeries, Hypospadias
Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery
Caudal block is often performed to relieve postoperative pain in pediatric urological surgery. Recently, pudendal block is also used in penile surgery and it has advantage because of less side effects such as transient weakness…
- Conditions
- Elective Penile Surgeries, Hypospadias, Urethral Fistula or Stricture After Hypospadias Repair, Penile Curvature
- Trial name
- NCT02848157
- Testing
- Dexmedetomidine, plain ropivacaine, Ropivacaine
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Hypospadias
Randomized Trial Of Urethroplasty With Stent Versus Without Stent For Hypospadias
Hypospadias is a birth condition in which the urine opening is on the underside of the penis. Surgery (urethroplasty) is the standard treatment.
- Trial name
- UCFStentRCT (NCT07243457)
- Testing
- Stent urethroplasty, Stentless urethroplasty
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Completed
Preputial Graft Urethroplasty in Primary Repair of Hypospadias
Introduction: Hypospadias repair is debated. There has been no perfect procedure until this moment. A graft is sometimes needed to fundamentally strengthen the narrow urethral plate.
- Trial name
- Hypospadias (NCT05660564)
- Testing
- DIGU Dorsal inlay preputial graft urethroplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sarah Magdy Abdelmohsen
Hypospadias
Clinical Trial to Assess the Safety and Efficacy of Investigational Product in Patients Due to Hypospadias Treatment Failure
The purpose of this trial is to assess the safety and efficacy of Holour in patients suffering from hypospadias treatment failure.
- Trial name
- HOLOUR (NCT05093166)
- Testing
- "Ex vivo" expanded autologous human oral epithelium containing stem cells
- Where
- Italy
- Volunteers
- 1 people
- Sponsor
- Holostem s.r.l.
Hypospadias
Long Term Outcome of Hypospadias Repair
Hypospadias is a common congenital abnormality of the penis which affects approximately 1 boy in 250. The opening of the urethra is located on the undersurface of the penis rather than the tip,the foreskin is deficient and there…
- Trial name
- NCT02103712
- Testing
- Qualitative
- Where
- United Kingdom
- Volunteers
- 170 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Hypospadia, Phimosis
Intelligence Changes Following Minor Surgery
Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted.
- Conditions
- Hypospadia, Phimosis, Inguinal Hernia
- Trial name
- NCT01483313
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- RenJi Hospital
Complication of Anesthesia
Effect of Caudal vs. Penile Block on the Incidence of Hypospadias Complications
Hypospadias is one of the most common congenital malformations in male babies, affecting approximately 1 in every 200-300 live male births.
- Trial name
- NCT06667947
- Testing
- caudal block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Hypospadias
Foreskin Graft Tubularized Incised Plate Urethroplasty vs Tubularized Incised Plate for Primary Hypospadias (FGTIP-TIP)
The purpose of this study is to determine the efficacy and safety of tubularized incised plate urethroplasty versus foreskin graft tubularized incised plate urethroplasty in primary hypospadias.
- Trial name
- FGTIP-TIP (NCT02497963)
- Testing
- Foreskin Graft-Tubularized Incised Plate, Tubularized Incised Plate
- Volunteers
- 68 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Hypospadias, Caudal Block
Effect of Caudal Block on Urethrocutaneous Fistula After Distal Hypospadias Repair
Hypospadias is one of the most common congenital urogenital anomalies in males, occurring in approximately 1 in every 200-300 male births.
- Conditions
- Hypospadias, Caudal Block, Pediatric Anesthesia
- Trial name
- NCT07675798
- Testing
- Caudal Block, General Anesthesia without Caudal Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
164 Boys for Hypospadias Surgery Under General Anesthesia With Caudal Block
Caudal Dexmedetomidine Analgesia in Pediatrics .
Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia. This prospective double blinded randomized comparative study is designed to evaluate the analgesic…
- Trial name
- NCT03791879
- Testing
- Caudal dexamedatomidine analgesia
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Hypospadias
Comparison of Analgesic Efficacy of Sacral Erector Spinae Plane Block and Caudal Epidural Block in Pediatric Patients Undergoing Hypospadias Surgery
The goal of this observational study is to learn about effects of block strategies (sacral erector spinae plane block - ESP, caudal block) on perioperative pain in pediatric patients undergoing hypospadias surgery.
- Trial name
- NCT07286786
- Testing
- Caudal Block Anesthesia, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Disorders of Sex Development, Hypospadias
Genetics of Differences of Sex Development and Hypospadias
This study seeks to identify genetic causes of conditions that affect the gonads and genitals, and to study the impact on families of receiving genetic results.
- Trial name
- NCT03102554
- Testing
- Return of Genetic Results
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Boston Children's Hospital
Hypospadias
Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair
From September 2014 to March 2015, 57 consecutive patients with hypospadias who are candidate for surgery will be enrolled in this randomized clinical trial.
- Trial name
- NCT02752308
- Testing
- Bupivacaine, General anesthesia, Dilute epinephrine injection
- Volunteers
- 60 people
- Sponsor
- Isfahan University of Medical Sciences
Hypospadias
Prophylactic Antibiotics or Placebo After Hypospadias Repair
The primary purpose of this study is to determine if routine use of prophylactic (preventive) antibiotics after repair of mid-to-distal hypospadias is beneficial.
- Trial name
- PROPHY (NCT02096159)
- Testing
- trimethoprim-sulfamethoxazole
- Where
- 2 sites in United States, Canada
- Volunteers
- 93 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Hypospadias, Hypospadias, Coronal
Penile Ischemia for Hypospadias Repair and The Patients and Surgeons Reported Outcomes
Although haemostasis aimed to maintain bloodless surgical field for better exposure for the surgeon, cosmetic impact, and decreased breakdown of repair, there is no trials regarding the impact of haemostasis techniques on surgeon…
- Conditions
- Hypospadias, Hypospadias, Coronal, Hypospadia, Repair, Tourniquet
- Trial name
- NCT04239066
- Testing
- Tourniquet, Non-tourniquet
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Hypospadias
PREDICT-H Study: Prospective Research on Essential Determinants Influencing Complication Trends in Hypospadias - a Landmark Prospective Multicenter Cohort Study Aimed at Improving Outcome Prediction in Hypospadias Surgery
Hypospadias is a common congenital anomaly with complex anatomy that influences surgical outcomes. Despite numerous surgical techniques, a lack of standardized preoperative assessment protocols and consensus on anatomical risk…
- Trial name
- PREDICT-H (NCT07017842)
- Where
- Qatar
- Volunteers
- 1,300 people
- Sponsor
- Sidra Medicine
Endocrinology, Disorders of Sexual Development
Retrospective Analysis of the Neonatal Management of Patients with an Antenatal Diagnosis of Genital Development Variation At the Hospital of Lyon
Variations in genital development (VDG) account for 0.5% to 1% of births. Advances in ultrasound techniques, as well as in prenatal diagnosis techniques, particularly in genetics, have led to improvements in the prenatal…
- Conditions
- Endocrinology, Disorders of Sexual Development, Prenatal Diagnosis, Psychology
- Trial name
- PECAN-VDG (NCT06687252)
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Hospices Civils de Lyon