Clinical trials: Perceived Pain
Any Condition Requiring Vulvar Biopsy
Pain Perception During Vulvar Biopsy
The purpose of this study is to compare pain control during vulvar biopsy following either (1) application of EMLA (a eutectic mixture of local anesthetics lidocaine 2.5% and prilocaine 2.5%) cream or (2) injection of 1%…
- Trial name
- NCT03654417
- Testing
- EMLA, Lidocaine
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Duke University
Pain
The Neurobiology of Expectancy and Pain Perception
This study will use using fMRI (functional Magnetic Resonance Imaging) to elucidate how contextual learning/expectation relieves or aggravates pain experience in the same cohort of subjects and the same study session.
- Trial name
- NCT01575106
- Testing
- Heat pain applied using TSA or CHEPS
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Orthopedic Disorder
Parental Perceptions on Prescription Opioid Use
This study involves an anonymous survey given to parents regarding their perceptions on prescription opioid use for pain control in children undergoing orthopedic surgery.
- Trial name
- NCT05344118
- Testing
- Survey
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Nationwide Children's Hospital
Idiopathic Parkinson's Disease
Observational Study With Neupro® to Evaluate the Patient´s Perception of Pain Associated With Parkinson´s Disease
The primary objective of this study is to evaluate the perception of pain associated with Parkinson´s Disease in patients who receive Neupro® for the first time.
- Trial name
- NEUPAD (NCT01606670)
- Where
- 27 sites in Austria, Germany
- Volunteers
- 93 people
- Sponsor
- UCB Pharma GmbH
Chronic Pain, Osteoarthritis
Effects of tDCS and tUS on Pain Perception in OA of the Knee
The purpose of this study is to investigate the effects of transcranial direct current stimulation (tDCS) in conjunction with transcranial ultrasound (TUS) on pain perception and functional limitations in people with…
- Trial name
- NCT02723929
- Testing
- active low-intensity transcranial electrical stimulation/active transcranial ultrasound
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Spaulding Rehabilitation Hospital
Pain, Hypogonadism
Effects of Testosterone Replacement on Pain Sensitivity and Pain Perception
Naturally occurring opiates (endorphins) decrease testosterone levels by inhibiting the synthesis of gonadotropin releasing hormone (GnRH) and also inhibiting testosterone synthesis by the testes.
- Trial name
- TAP (NCT00351819)
- Testing
- AndroGel
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Boston University
Postoperative Pain
Postoperative Environment on Pain Following Pelvic Reconstructive Surgery
This study is to determine if patients following prolapse repair including vaginal vault suspension have decreased pain measured via a visual analog scale (VAS) on postoperative day one and just prior to discharge when exposed to…
- Trial name
- NCT03379753
- Testing
- music and positive images
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- TriHealth Inc.
Pain, Acute, Anesthesia, Local
Variable Perception of Cutaneous Stimulation
Perception of cutaneous sensory stimulation shows a large range of variability across multiple populations. Understanding this variability is critical to medical practice as interpretation of discomfort and pain is critical to…
- Conditions
- Pain, Acute, Anesthesia, Local, Dermatology/Skin - Other
- Trial name
- NCT03467685
- Testing
- Vibratory Anesthetic Device (VAD)
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pain
Pain Perception With Tenaculum Placement
Randomized controlled trial that compares methods of tenaculum placement during intrauterine device insertion and their effect on pain.
- Trial name
- NCT02969421
- Testing
- Cough method for placement of tenaculum, Slow Tenaculum Placement of tenaculum
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Duke University
Infant, Newborn, Infant, Premature
Effect of a Vibratory Stimulus on Mitigating Nociception-specific Responses to Skin Puncture in Neonates
The assessment and treatment of pain in neonates remains a challenge. In an effort to improve the quality of care while limiting opioid-related adverse effects, this study aims to determine the efficacy of a non-pharmacological…
- Conditions
- Infant, Newborn, Infant, Premature, Pain Perception, Pain Measurement
- Trial name
- NCT04050384
- Testing
- Baby GentleStick
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Lance M Relland, MD, PhD
Acute Pain
Vasopressin and Pain Perception in the Brain
The feeling of pain is not just a sensory experience, but is also influenced by emotions, beliefs and expectations, making pain a highly subjective experience.
- Trial name
- NCT03446456
- Testing
- Arginine vasopressin, Saline, Observational learning
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Mandibular Anterior Crowding, Piezocision
Efficiency of Piezotome-Corticision Assisted Orthodontics
The aim of this study is to evaluate the hypothesis that a piezotome-corticision procedure will have a transient acceleratory effect on the rate of tooth alignment and the overall treatment time.
- Conditions
- Mandibular Anterior Crowding, Piezocision, Pain Perception
- Trial name
- NCT02026258
- Testing
- Piezotome-Corticision, Orthodontics
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- UConn Health
Pain
The Effect of Liposomal Lidocaine on Perceived Pain in Children During Percutaneous Interosseous Pin Removal in the Outpatient Setting
The removal of smooth, percutaneous pins (Perc Pins), which are used for fracture fixation, occurs once adequate bone healing has taken place.
- Trial name
- NCT01542125
- Testing
- Liposomal Lidocaine
- Volunteers
- 281 people
- Sponsor
- University of Alberta
Fibromyalgia
Investigation of AVACEN Thermal Exchange System for Fibromyalgia Pain
Hypothesis: Daily use of the AVACEN Thermal Exchange System for 4 weeks will show improved Fibromyalgia pain and functioning markers, as assessed by biomarkers and clinical and psychological assessment.
- Trial name
- AVACEN: TES (NCT01619579)
- Testing
- AVACEN Thermal Exchange System
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Avacen, Inc.
Anxiety, Pain
Virtual Reality Decreases Child Anxiety and Pain as Well as Caregiver Anxiety and Pain Perception During Orthopaedic Clinic Office Procedures
The purpose of this study is to demonstrate that the use of a virtual reality experience can decrease child and caregiver anxiety and pain for simple orthopaedic office procedures.
- Trial name
- NCT05708586
- Testing
- Control, Virtual Reality (VR)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Michigan
Pain, Surgery
The Impact of SCN9A Gene Polymorphism on Individual Pain Perception in the General Population
This study was conducted to explore whether the non-synonymous single-nucleotide polymorphisms in SCN9A gene can predict individual basal pain perception and postoperative pain intensity in the general population undergoing upper…
- Trial name
- NCT01507493
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xianwei Zhang
Pain
Effects of Transcranial Direct Current Stimulation on Pain Perception
The purpose of this study is to determine whether a new medical technology can temporarily alter pain perception. The new technology is called Transcranial direct current stimulation (tDCS).
- Trial name
- tDCS-CBT (NCT01860950)
- Testing
- anodal tDCS, cathodal tDCS
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pregnancy
Local Anesthesia and Pain Perception During an Amniocentesis
This study is been designed to answer the question of whether local anesthesia (1% lidocaine) decreases the perception of pain associated with amniocentesis in a randomized double blind placebo controlled manner.
- Trial name
- NCT00583011
- Testing
- Local Anesthesia
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Anxiety, Pain, Procedural
Lavender Aromatherapy to Decrease Anxiety/Pain Perception During Office Hysteroscopy
Office hysteroscopy is an invaluable practice to treat a myriad of gynecological processes. However, a limiting factor is the perceived pain and anxiety.
- Trial name
- NCT06316934
- Testing
- Lavandula angustifolia, Aura Cacia
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pain, Surgery
The Possible Correlations Between the Genes Related to Pain Sensation and the Pain Sensitivity in the General Population
Objective: This study was conducted to explore the possible correlation between some gene related to pain sensation and individual basal pain perception and postoperative pain intensity in the general population.
- Trial name
- NCT01950078
- Where
- China
- Volunteers
- 1,533 people, healthy volunteers welcome
- Sponsor
- Xianwei Zhang