Clinical trials: Perception of Disease, open to volunteers
Angelman Syndrome
Use of Eye Tracking to Study Social Perception Abnormalities in Children With Angelman Syndrome
Angelman syndrome (AS) is a rare neurogenetic disorder that affects approximately 1 in 15,000 children - approximately 500,000 people worldwide.
- Trial name
- EYEANGEL (NCT06737718)
- Testing
- Eye tracking, Data collection from patients' medical files, questionnaires
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain Management, Abortion
Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement
The purpose of this study is to improve pain management for participantswho need osmotic dilators for cervical preparation the day before their second trimester abortion procedure.
- Conditions
- Pain Management, Abortion, Second Trimester Abortion, Dilation and Evacuation
- Trial name
- PCB-KinD (NCT07487246)
- Testing
- Ketorolac, oral ibuprofen, Lidocaine HCl 1%
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Rush University Medical Center
Major Depressive Disorder
Neural Correlates of Stress and Perceived Control in Adolescent Depression
Lack of perceived control, particularly during stress, has been critically implicated in major depressive disorder (MDD) and anhedonic symptoms, especially among female adolescents; yet the neural underpinnings of perceived…
- Trial name
- NCT04788524
- Testing
- Computer Task Manipulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Hearing Loss, Cognitive Impairment, Mild
ENACT Program on Auditory Perception and Function, Cognitive Function and Health-related Quality of Life
Although previous studies indicated that tackling hearing loss may have a secondary benefit in improving cognitive function and delaying the onset of dementia, a more integrated care approach to optimize both hearing and…
- Trial name
- NCT06955494
- Testing
- Empowerment Network for Auditory-Cognitive Training (ENACT) Program, Usual Care
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- The University of Hong Kong
Schizophrenia, Schizoaffecitve Disorder
Digital Therapeutics for Social Cognitive Function in Schizophrenia Spectrum Disorder
The purpose of this study is to evaluate the safety and preliminary effectiveness of a smartphone-based digital therapeutic application (AffectUs) for improving social cognition, particularly emotion processing and social cue…
- Trial name
- NCT07755605
- Testing
- Digital therapeutic (AffectUs), Psychoeducational materials
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Blood Pressure Management, Blood Pressure Monitoring, Ambulatory
Impact of Resistance Training Intensity on Blood Pressure
The goal of the clinical trial is to understand the effect of two resistance training protocols employing different loading intensities (% of 1 repetition maximum; 1-RM), but with standardized effort intensity (2 repetitions in…
- Conditions
- Blood Pressure Management, Blood Pressure Monitoring, Ambulatory, Blood Pressure, High, Blood Pressure
- Trial name
- HEART (NCT06845514)
- Testing
- Condition LL-RE, Control, Condition HL-RE
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Stroke, Visual Impairment
Effectiveness of AV-stimulation in Immersive VR to Improve Visual Perception and Driving Performance
The goal of this clinical trial is to evaluate the effectiveness of an immersive virtual-reality (IVR) based stimulation program, in improving visual perception for people who have lost their driver's license due to perceptual or…
- Conditions
- Stroke, Visual Impairment, Low Vision, Virtual Reality
- Trial name
- Re:DriVR (NCT05703360)
- Testing
- Audiovisual Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University Health Network, Toronto
Malocclusion
Evaluation of the Perceived Experience of Patients Treated With Aligners With Two Different Timings
The primary aim of the study is to compare the perception of pain and discomfort with two different protocols of attachments' placement during clear aligner therapy: the conventional protocol (CP), when attachments' placement is…
- Trial name
- ALLIN-1 (NCT06536335)
- Testing
- Biomax Nuvola aligners
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Alzheimer Disease, Caregivers of Alzheimer's Disease or Memory Problem Patients
Psychological Counseling Program for Alzheimer's Patients' Caregivers
Purpose: To investigate the effects of a psychological counseling program (PsychoCP) applied to caregivers of Alzheimer's patients on perceived stress, psychological well-being and care burden.
- Conditions
- Alzheimer Disease, Caregivers of Alzheimer's Disease or Memory Problem Patients, Perceived Stress, Well-Being (Psychological Flourishing)
- Trial name
- PsychoCP (NCT06755476)
- Testing
- Psychological Counseling Program
- Volunteers
- 80 people
- Sponsor
- Aydan Akkurt Yalçıntürk
Pain and Anxiety in Children With MIH
Preemptive Analgesia for Pain and Anxiety Control in Children With MIH
This randomized, triple-blinded clinical trial aims to evaluate the effect of preemptive analgesia using ibuprofen on pain perception and anxiety during restorative treatment of first permanent molars in children diagnosed with…
- Trial name
- NCT07374354
- Testing
- ibuprofen 100mg/ml oral suspension syrup
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- October University for Modern Sciences and Arts
Diabetes Mellitus, Diabetic Foot Ulcer (DFU)
Risk Perception Intervention for High-Risk Diabetic Foot
This study aims to evaluate the effect of health education based on information framing effects on foot ulcer risk perception in patients at high risk of diabetic foot.
- Conditions
- Diabetes Mellitus, Diabetic Foot Ulcer (DFU), Risk Perception, Peripheral Neuropathy With Type 2 Diabetes
- Trial name
- NCT07581262
- Testing
- Gain-Framed, Loss-Framed, Routine Care
- Volunteers
- 90 people
- Sponsor
- The Third Affiliated Hospital of Soochow University
Neuromotor Dysphagia After Acute Stroke
The Cooling Sensation Safe Deglution Study
Dysphagia is a common complication in patients who have suffered a cerebrovascular accident (CVA), with an incidence ranging from 29% to 81%.
- Trial name
- NCT06936501
- Testing
- Traditional flavor ONS (vanilla or strawberry, by choice), Refreshing and stimulating flavor ONS (mango-peppermint or lemon-mint, by choice)
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Autism, Autism Spectrum Disorder
The Impact of Sensory Integration on Attention in Autism
The study aims to examine how the mode of presentation of visual and auditory stimuli-separate or simultaneous-affects accuracy and reaction time in visual-auditory association in participants with Autism Spectrum Condition (ASC)…
- Trial name
- NCT06872229
- Testing
- Autism Spectum Conditions - intervention, Typical Development - intervention
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Healthcare-associated Infections, Quality Culture and Leadership in Intensive Care
Perceptions of Leadership in Quality Culture for Infection Prevention Among Intensive Care Nurses and Unit-Based Assessment of Antimicrobial Resistance Indicators in Intensive Care Units
This study aims to examine intensive care nurses' perceptions of leadership in quality culture for infection prevention and to investigate antimicrobial resistance indicators at the intensive care unit level.
- Conditions
- Healthcare-associated Infections, Quality Culture and Leadership in Intensive Care, Infection Prevention and Control
- Trial name
- NCT07782372
- Volunteers
- 127 people
- Sponsor
- Yeliz Sapulu Alakan
Cardiovascular Disease
Awareness of Risk Factors and Perception of Cardiovascular Risk in Secondary Prevention Among Women and Men
The present research project aims to assess, through a survey, awareness of general and sex/gender-specific cardiovascular risk factors, as well as the perception of the risk of developing further cardiovascular diseases, among…
- Trial name
- CORPS-CV (NCT07521436)
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Hemophilia
Feasibility and Safety of Blood-Flow-Restriction Training in Patients With Hemophilia
In the course of a cross-over study design, 12 patients with hemophilic arthropathy will perform a training load on the knee extensor muscles.
- Trial name
- NCT07259356
- Testing
- Control, BFR Exercise (50% of the LOP) while Leg Press Exercise (4 Sets, All out)
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- University Hospital, Bonn
Hair Thinning
Evaluating the Combined Use of Supplement and Serum in Promoting Hair Growth in Women With Self-perceived Thinning Hair
The goal of this clinical trial is to test how safe and effective it is to improve hair growth using an active gummy and serum combination treatment when compared to an inactive treatment combination in women with self-perceived…
- Trial name
- NCT07041489
- Testing
- Active Comparator- Xtressé™ Supplement and Serum
- Where
- 2 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical and Cosmetic Research
Cleft Lip and Palate, Speech Disorders in Children
High and Low Intensity Speech Intervention in Children With a Cleft Palate: Perceptions of Children, Their Caregivers and Speech-language Pathologists
A cleft (lip and) palate (CP±L) is the most common congenital abnormality of the face and skull with a significant social impact, affecting speech, hearing, feeding, oral behavior, dentition and satisfaction with appearance.
- Trial name
- NCT06895395
- Testing
- High intensive combined phonetic-phonological intervention, Low intensive combined phonetic-phonological intervention
- Where
- Belgium
- Volunteers
- 175 people
- Sponsor
- University Ghent
Asthma
Asthma Symptom Perception Study
Asthma affects 8% of the United States population ages >60 years and causes considerable harm: older adults are 4 times more likely to die from asthma and have twice the risk of hospitalization.
- Trial name
- ASP RCT (NCT06612294)
- Testing
- PEF Interventional Session, Control Sessions, Control Booster
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Bone Neoplasms, Soft Tissue Neoplasms
Stress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer
This prospective observational study will follow adults who are scheduled for a clinically indicated biopsy because of a suspected solid tumor involving bone or soft tissue.
- Conditions
- Bone Neoplasms, Soft Tissue Neoplasms, Anxiety, Stress, Psychological
- Trial name
- BIOPSY-STRESS (NCT07727434)
- Testing
- Routine Diagnostic and Treatment Pathway
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University