Clinical trials: Perceptual Disorders, open to volunteers
Analgesia, Vastus Lateralis Nerve Block
Analgesic Efficacy of Blocking Nerve to Vastus Lateralis Muscle Versus Lateral Femoral Cutaneous Nerve After Knee Surgeries
This study aims to compare the analgesic efficacy and functional outcomes of blocking the nerve to the vastus lateralis (NVL) muscle versus the lateral femoral cutaneous nerve (LFCN).
- Conditions
- Analgesia, Vastus Lateralis Nerve Block, Lateral Femoral Cutaneous Nerve Block, Knee Surgeries
- Trial name
- NCT06809842
- Testing
- Vastus lateralis nerve block, Lateral femoral cutaneous nerve block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Kafrelsheikh University
Schizophrenia, Hallucinations
HD-tDCS for Hallucinations
One in three patients with schizophrenia experiences hallucinations that are refractory to conventional pharmacotherapy. For refractory auditory hallucinations, transcranial direct current stimulation -tDCS- has been proposed as…
- Trial name
- TARGET (NCT06208176)
- Testing
- High-definition transcranial direct current (HD-tDCS), active condition
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Hôpital le Vinatier
Intensive Care Medicine, Respiratory Distress Syndrome (RDS)
Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol
Sedation (painkillers and sedative drugs) treats pain, reduces suffering, and helps patients in the intensive care unit (ICU) receiving extracorporeal membrane oxygenation (ECMO) remain comfortable.
- Conditions
- Intensive Care Medicine, Respiratory Distress Syndrome (RDS), Sedation and Analgesia, ExtraCorporeal Membrane Oxygenation (ECMO)
- Trial name
- ECMO-SED (NCT07032987)
- Testing
- Not an intervention study
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Non-steroidal Anti-inflammatory Drugs, Pleurodesis
Non-steroidal Anti-inflammatory Drugs in Pleurodesis
Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended in a multimodal pain management to reduce pain intensity and to spare opioid use.
- Conditions
- Non-steroidal Anti-inflammatory Drugs, Pleurodesis, Pneumothorax, Pain Management
- Trial name
- KETOTHORAX (NCT06731647)
- Testing
- pleurodesis procedures, KETOPROFEN(RP19583)
- Where
- France
- Volunteers
- 358 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hip Fractures (ICD-10 72.01-72.2), Post Operative Analgesia
Suzetrigine (Journavx) as Multimodal Therapy for Pain Management in Adults Undergoing Surgery for Hip Fracture
The goal of this clinical trial is to learn whether suzetrigine (Journavx®), when added to standard multimodal pain management, can reduce opioid use while providing adequate pain control in adults undergoing surgery for an acute…
- Trial name
- STRIDE-HIP (NCT07905404)
- Testing
- Suzetrigine (Journavx)
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Beth Israel Deaconess Medical Center
Adhesive Capsulitis of the Shoulder, Frozen Shoulder
Evaluation and Treatment of Adhesive Capsulitis Using Non-invasive Neurostimulation Devices
The goal of this randomized controlled trial is to compare the integrity of somatosensory processing with transcranial magnetique stimulation (TMS) and corticospinal excitability of the affected shoulder in individuals with…
- Trial name
- NCT06795932
- Testing
- Tendon Vibration, Exercices
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Chicoutimi
Spinal Fusion, Adolescent Idiopathic Scoliosis
Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients…
- Trial name
- NCT06067893
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nichole Doyle
Pain Management, Perioperative Analgesia
From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
To compare the effectiveness of continuous regional anaesthesia with standard pain management strategies for the treatment of acute pain in patients with war-related lower limb trauma.
- Conditions
- Pain Management, Perioperative Analgesia, War-Related Injuries
- Trial name
- CRA-WAR-LIMB S (NCT07474506)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Parkinson's Disease
Speech Learning and Speech Production in Parkinson's Disease
Parkinson's disease, a common movement disorder that results from a breakdown in the brain, often leads to challenges with talking, but less is known about the relationship between difficulties with talking and difficulties with…
- Trial name
- NCT07403539
- Testing
- Intensity learning, Intensity discrimination, Rate learning
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- State University of New York at Buffalo
Fibromyalgia, Musculoskeletal Pain
Light Bulb Stimuli to Reduce Chronic Pain
This pilot randomized, double-blind, crossover clinical trial will evaluate the feasibility and preliminary efficacy of chromatic (colored) light exposure for reducing pain severity and pain sensitivity in adults with…
- Trial name
- Light Bulb (NCT07825792)
- Testing
- S-Cone Stimulating Chromatic Light, Equal-Energy White Light
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Analgesia, Post Operative Pain
Clinical Utility of the Numerical Verbal Scale (NVS) and the Pain and Functional Activity Scale (PFAS) in the Management of Rescue Analgesia in Acute Postoperative Pain. Randomized Study.
Adequate postoperative pain management, along with mobilization and early oral nutrition, is the foundation for optimal recovery after surgery.
- Conditions
- Analgesia, Post Operative Pain, Acute Pain, Functional; Anesthesia
- Trial name
- EVN/EDAF (NCT07310953)
- Testing
- Group A: Rescue analgesia if NVS>4, Group B: Rescue analgesia if NVSm > 4 + FAS C
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Pain, Postoperative, Heart Surgery
Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)
This randomized, prospective, single-blinded study aims to compare the efficacy of ultrasound-guided serratus anterior plane (SAP) block combined with serratus-intercostal interfascial plane (SIP) block versus local wound…
- Conditions
- Pain, Postoperative, Heart Surgery, Analgesia
- Trial name
- NCT06968065
- Testing
- Ultrasound-guided serratus anterior plane block and serratus-intercostal interfascial plane block with bupivacaine, Local wound infiltration with bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- İstanbul Yeni Yüzyıl Üniversitesi
Analgesia, Post Operative Pain
The Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section
We aim to investigate the value of vitamin B (B1, B6, B9, B12) on post-cesarean section analgesia in addition to the standard opioid-sparing multimodal regimen to achieve more robust analgesia with minimal side effects.
- Conditions
- Analgesia, Post Operative Pain, Cesarean Section
- Trial name
- NCT06446830
- Testing
- multimodal analgesia and vitamin B, standard multimodal analgesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Chronic Pain, Chronic Pain Syndrome
Shiatsu for Chronic Non-Inflammatory Pain in Children and Adolescents
The goal of this clinical trial is to learn if adding Shiatsu therapy to standard treatment can improve quality of life in children and adolescents with chronic pain that is not caused by inflammation.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain and Comorbid Emotional Problems, Chronic Pain, Psychogenic
- Trial name
- ShiQoL (NCT06929598)
- Testing
- Shiatsu Therapy
- Where
- 2 sites in Israel
- Volunteers
- 40 people
- Sponsor
- Tel Aviv University
Pain Management
Evaluation of Paro, a Therapeutic Assistance Robot in Analgesic Management During the Placement of a Peripheral Intravenous Line in Infants and Children.
Peripheral intravenous catheterization is one of the most frequently performed procedures in pediatric emergency departments and hospital units.
- Trial name
- PARO (NCT07299006)
- Testing
- Experimental group: Standard multimodal pain management strategy supplemented with the PARO therapeutic robot., Non-pharmacological and standard pharmacological interventions.
- Where
- 5 sites in France
- Volunteers
- 120 people
- Sponsor
- Fondation Lenval
Pain Management
Stress Ball Application on Anxiety and Pain During Pap Smear Test
A negative pelvic examination experience may deter women from returning for follow-up tests, thus reducing the intended benefit of gynecological screening.
- Trial name
- NCT06682052
- Testing
- anti-stress ball
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hitit University
Advanced Cancer, Pain
Integrated Smartphone Technology to Alleviate Malignant Pain (I-STAMP) Testing
The purpose of the study is to evaluate if the smartphone app, I-STAMP (Integrated Smartphone Technology to Alleviate Malignant Pain), helps participants with cancer pain manage symptoms and keep track of medications.
- Trial name
- NCT06117709
- Testing
- I-STAMP
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Dana-Farber Cancer Institute
PARKINSON DISEASE (Disorder)
The Role of Priors in Hallucinatory Perception in Parkinson's Disease
The goal of this observational study is to better understand the mechanisms of hallucinations in patients with Parkinson's disease.
- Trial name
- LEAP-PARK (NCT07427498)
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Limb Pain, Phantom, Residual Limbs Pain
Pain and Disability Outcomes in Post Amputation Patients
The objective of this study is to evaluate efficacy of varied medical and procedural therapies used to treat pain after surgical amputation of a limb.
- Conditions
- Limb Pain, Phantom, Residual Limbs Pain, Disability Physical
- Trial name
- NCT05716321
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Milton S. Hershey Medical Center
Pain, Postoperative
Quadratus Lumborum Block for Total Hip Arthroplasty
The quadratus lumborum (QL) block is a fascial plane block that has been described to provide analgesia from T7-L3 dermatomes. The investigators aim to evaluate the efficacy of QL blocks in patients undergoing primary total hip…
- Trial name
- NCT05247255
- Testing
- Active Comparator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles