Clinical trials: Percutaneous Coronary Intervention (PCI)
ST Elevation Myocardial Infarction
Trial Comparing Radial and Femoral Approach in Primary Percutaneous Coronary Intervention (PCI)
Percutaneous coronary interventions (PCIs) from the femoral approach have more bleeding complications related to access site in comparison to the radial approach in patients with acute coronary syndrome (ACS).
- Trial name
- STEMI-RADIAL (NCT01136187)
- Testing
- Access site in primary PCI
- Where
- 4 sites in Czechia
- Volunteers
- 707 people
- Sponsor
- Charles University, Czech Republic
Coronary Arteriosclerosis
Effects of Celecoxib After Percutaneous Coronary Intervention
Several studies including ours have reported that celecoxib improves endothelium-dependent vasodilation and reduces inflammation and neointimal hyperplasia.
- Trial name
- NCT00292721
- Testing
- Celecoxib
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- Seoul National University Hospital
Percutaneous Coronary Intervention, Myocardial Revascularization
Clinical Study of Chinese Herbal Compound Qidan Xiaoke Granules in Patients After Coronary Revascularization
1. Evaluate the efficacy and safety of Qidan Xiaohe granules in patients after coronary revascularization surgery; 2. Develop a traditional Chinese medicine rehabilitation treatment plan and evaluation system for the use of Qidan…
- Conditions
- Percutaneous Coronary Intervention, Myocardial Revascularization, Coronary Artery Disease
- Trial name
- NCT07616544
- Testing
- Qidan Xiaoke Granules + Standard Medical Therapy
- Volunteers
- 164 people
- Sponsor
- Liu Qiang
Acute Coronary Syndrome, ST Elevation Myocardial Infarction
A Trial of Routine Aspiration Thrombectomy With Percutaneous Coronary Intervention (PCI) Versus PCI Alone in Patients With ST-Segment Elevation Myocardial Infarction (STEMI) Undergoing Primary PCI
This is an international, randomized, controlled, parallel group study in which patients with ST-Segment Elevation Myocardial Infarction (STEMI) will be allocated to one of the following: Manual aspiration thrombectomy with…
- Conditions
- Acute Coronary Syndrome, ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
- Trial name
- TOTAL (NCT01149044)
- Testing
- Percutaneous Coronary Intervention with or without manual aspiration thrombectomy
- Where
- 87 sites in United States, Australia and 18 more
- Volunteers
- 10,732 people
- Sponsor
- Population Health Research Institute
Chronic Total Occlusion, Occlusion
Impact of CTO PCI (Chronic Total Occlusion Percutaneous Intervention) on Regular Physical Activity
Heart disease is a leading cause of death in the US. . Heart blood vessel chronic total occlusions are 100% blockages of the heart vessels. These patients often suffer from chest pain, shortness of breath, and depression.
- Trial name
- NCT05440084
- Testing
- Chronic total occlusion percutaneous coronary intervention
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Minneapolis Heart Institute Foundation
Coronary Artery Disease, Percutaneous Coronary Intervention
The xDAPT External Validation Study
Dual antiplatelet therapy (DAPT) is routinely recommended after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation to prevent thrombotic complications.
- Trial name
- xDAPT (NCT06736626)
- Testing
- Percutaneous coronary intervention
- Where
- United States
- Volunteers
- 30,000 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Coronary Artery Disease, Percutaneous Coronary Intervention
Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.
Patients who undergo percutaneous coronary intervention (PCI) are commonly treated with antiplatelet therapy to prevent stent thrombosis and recurrence of events.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndromes, Antiplatelet Therapy
- Trial name
- HI-TECH 2 (NCT07582835)
- Testing
- Clopidogrel, Ticagrelor, Prasugrel
- Where
- Switzerland
- Volunteers
- 355 people
- Sponsor
- Cardiocentro Ticino
Percutaneous Coronary Intervention
Radial Artery Patency and Bleeding, Efficacy, Adverse evenT Trial
The objectives of this study are to demonstrate the safety and efficacy of the new 6Fr sheath (Glidesheath slender; Terumo, Tokyo,Japan ; GSS) compared with the contemporary 5Fr sheath (Hydrophilic coating sheath from Terumo…
- Trial name
- RAPandBEAT (NCT02269449)
- Testing
- 6Fr Glidesheath Slender sheath, 5Fr sheath, Hemostasis with TR band
- Volunteers
- 1,900 people
- Sponsor
- NPO International TRI Network
Percutaneous Coronary Intervention
Comparative Registry of the PROmus™, ENdeavor™ and CYpher™ Drug Eluting Stents
The purpose of this study is to collect real-life data of the Promus™ stent, the Cypher™ stent and the Endeavor™ stent in routine clinical practice, and compare outcomes.
- Trial name
- ProEnCy (NCT00930878)
- Testing
- Cardiac Stenting
- Where
- Germany
- Volunteers
- 1,934 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease (CAD), Percutaneous Coronary Intervention (PCI)
Minicrush Versus Culotte Stenting in Complex Coronary Bifurcation Lesions:The Multicenter T-REX II Registry
Percutaneous coronary intervention (PCI) of complex coronary bifurcation lesions frequently requires an upfront two-stent strategy.
- Conditions
- Coronary Artery Disease (CAD), Percutaneous Coronary Intervention (PCI), Bifurcation Coronary Artery Disease
- Trial name
- NCT07849335
- Testing
- Percutaneous Coronary Intervention with Minicrush
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- San Luigi Gonzaga Hospital
Coronary Artery Disease, Percutaneous Coronary Intervention
Different Doses of Colchicine on hsCRP
Colchicine reduced atherothrombotic cardiovascular events in the COLCOT and LoDoCo2 studies. US Food and Drug Administration approved colchicine as the first anti-inflammatory drug for cardiovascular diseases on June, 2023.
- Trial name
- NCT06078904
- Testing
- Colchicine 0.5 MG, Colchicine 0.375 MG, Colchicine 0.25 MG
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Primary Percutaneous Coronary Intervention
Prolonged Enoxaparin In Primary Percutaneous Coronary Intervention; A Pilot Pharmacodynamic Study
Heart attacks are caused by a clot blocking one or more of the heart arteries (coronary arteries). When complete blockage of one of the arteries occurs, emergency treatment to unblock the affected artery and rescue the heart…
- Trial name
- PENNY PCI (NCT03146858)
- Testing
- Enoxaparin
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Treatment in Calcified Coronary Disease
Shockwave Lithoplasty Compared to Cutting Balloon Treatment in Calcified Coronary Disease - A Randomized Controlled Trial
The Short-Cut trial is a prospective, investigator-initiated, multicenter, randomized controlled trial that is designed to compare the efficacy of cutting balloon angioplasty vs.
- Trial name
- Short-Cut (NCT06089135)
- Testing
- Intravascular Lithotripsy, Cutting Balloon
- Where
- 22 sites in United States
- Volunteers
- 413 people
- Sponsor
- Baim Institute for Clinical Research
ST Elevation Myocardial Infarction
Single Catheter Primary Percutaneous Coronary Intervention Method in Patients With ST Elevation Myocardial Infarction
The goal of this clinical trial is to test reducing procedure time of percutaneous coronary intervention (PCI) in ST elevation myocardial infarction by single catheter PCI (SC-PCI) method.
- Trial name
- SPEEDYPCI (NCT05604976)
- Testing
- Percutaneous coronary intervention
- Where
- Japan
- Volunteers
- 430 people
- Sponsor
- Tokai University
Coronary Artery Disease
The Dual Antiplatelet Therapy Study (DAPT Study)
The DAPT Study is a double blind randomized controlled trial intended to determine the appropriate duration for dual antiplatelet therapy (the combination of aspirin and a second anti-clotting medication) as well as the safety…
- Trial name
- NCT00977938
- Testing
- Clopidogrel & Aspirin, Prasugrel & Aspirin
- Where
- 256 sites in United States, Australia and 8 more
- Volunteers
- 25,682 people
- Sponsor
- Baim Institute for Clinical Research
Percutaneous Coronary Intervention, Anxiety
The Effect of Listening to Music and Stress Ball Application on Patients' Anxiety Level and Hemodynamic Parameters During PCI
In this study, it was aimed to determine the effects of listening to music and applying a stress ball on patients' anxiety level and hemodynamic parameters during percutaneous coronary intervention (PCI).
- Conditions
- Percutaneous Coronary Intervention, Anxiety, Hemodynamics
- Trial name
- NCT05514574
- Testing
- Music, Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Keriman Yildiz
Coronary Artery Disease
NAVIGATE GRX Study
The objective of the present study is to detail the results of robotic-assisted PCI using technIQ automated movements in real-world clinical practice.
- Trial name
- NCT04883008
- Testing
- CorPath GRX with technIQ automated movements enabled (technIQ ON), CorPath GRX with technIQ automated movements disabled (technIQ OFF).
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Myocardial Infarction
A Clinical Evaluation of Everolimus Eluting Coronary Stents in the Treatment of Patients With ST-segment Elevation Myocardial Infarction: EXAMINATION Study
This study is a prospective, randomized controlled, single blind, two-arm, multi center clinical evaluation. A total of 1500 patients will be enrolled in the study.
- Trial name
- NCT00828087
- Testing
- Everolimus Eluting Coronary Stent System, cobalt chromium balloon expandable stent ( non drug eluting stent Arm)
- Where
- 11 sites in Italy, Netherlands and 1 more
- Volunteers
- 1,504 people
- Sponsor
- Spanish Society of Cardiology
ST Elevation Myocardial Infarction, Arrhythmia Ventricular
Different Reperfusion Timing and Ventricular Arrhythmias in STEMI Patients
The aim of this study was to investigate the association between different reperfusion timing and ventricular arrhythmias (VAs) to provide evidence for clinical decision-making for patients with ST-segment elevation myocardial…
- Trial name
- NCT04660474
- Where
- China
- Volunteers
- 517 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Radiation Exposure
Randomized Comparison of Radiation Exposure to Operators in Coronary Intervention Between Right Radial and Left DRA
The purpose of this study is to show that the radiation exposure of the left distal radial artery approach is superior to the conventional right radial artery approach in terms of less radiation exposure.
- Trial name
- DOSE (NCT05702060)
- Testing
- Radial Artery Puncture Method for Coronary Angiography and Intervention
- Where
- 3 sites in South Korea
- Volunteers
- 1,010 people
- Sponsor
- Yonsei University