Clinical trials: Percutaneous Coronary Intervention Patients
Acute Coronary Syndrome, Percutaneous Coronary Intervention
Bivalirudin in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention.
The study is an investigator-sponsored, prospective, multicenter, randomized, open-label study designed to compare efficacy and safety between bivalirudin and heparin in elderly patients with acute coronary syndrome undergoing…
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Aging, Anticoagulants and Bleeding Disorders
- Trial name
- NCT04046029
- Testing
- Bivalirudin, Heparin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Stable Coronary Syndrome, Percutaneous Coronary Intervention
A Novel Strategy For Personalized Long-Term Dual Antiplatelet Therapy (RAPID EXTEND PILOT STUDY)
In patients with heart attacks, the current standard of care is to restore blood flow through percutaneous coronary intervention (PCI). This is done using stents (metal meshes) that opens up blockages.
- Conditions
- Stable Coronary Syndrome, Percutaneous Coronary Intervention, Antiplatelet Therapy, Ticagrelor
- Trial name
- NCT03224923
- Testing
- Ticagrelor 60mg, Clopidogrel 75mg, Aspirin 81 mg
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Ottawa Heart Institute Research Corporation
ST Segment Elevation Myocardial Infarction, Elective Percutaneous Coronary Intervention
Prevention of Coronary Slow Flow or No-Reflow During EPCI in Patients With Acute STEMI
Elective percutaneous coronary intervention (EPCI) is the common treatment of ST segment elevation myocardial infarction (STEMI).Slow flow / no-reflow phenomenon following EPCI in STEMI patients has been a serious and common…
- Trial name
- NOSLOWFLOW-Ⅱ (NCT03406832)
- Testing
- Nitroprusside Sodium, Tirofiban Hydrochloride, Heparinized saline
- Where
- 28 sites in China
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Erythrocyte Transfusion, Percutaneous Coronary Intervention
The Long-term Clinical Outcomes and Patterns of Transfusion in PCI Patients: Retrospective Cohort Study
A nationwide retrospective cohort study. To investigate the long-term patterns of transfusion and clinical outcomes of patients undergoing PCI.
- Conditions
- Erythrocyte Transfusion, Percutaneous Coronary Intervention, Revascularization
- Trial name
- TFPCI (NCT03776266)
- Testing
- No intervention is required due to retrospective observational study
- Where
- South Korea
- Volunteers
- 48,786 people
- Sponsor
- Samsung Medical Center
STEMI, Percutaneous Coronary Intervention
Bivalirudin in Elderly Patients With Acute ST-segment Elevation Myocardial Infarction
The study is an investigator-sponsored, prospective, multicenter, randomized, open-label study designed to compare efficacy and safety between bivalirudin and heparin in elderly patients with acute ST-segment elevation myocardial…
- Conditions
- STEMI, Percutaneous Coronary Intervention, Aged
- Trial name
- BEST (NCT03882775)
- Testing
- Bivalirudin, Heparin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Coronary Artery Disease, Percutaneous Coronary Intervention
Clinical and Genetic Characteristics of Coronary Artery Disease in Chinese Young Adults
The aim of this study is to identify genetic loci,or gene variations contributing to the development of coronary artery disease (CAD) in Chinese young adults.
- Trial name
- GRAND (NCT02496858)
- Where
- 38 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Percutaneous Coronary Intervention
The Safety and Efficacy of DIOR Balloon in Coronary Bifurcation Lesions
To evaluate the safety and effectiveness of paclitaxel-eluting coronary artery balloon dilation catheter (DIOR) in revascularization of coronary bifurcation lesions compared with paclitaxel-eluting balloon (Bingo), and to provide…
- Trial name
- BEYOND-II (NCT03820622)
- Testing
- Paclitaxel-Eluting Coronary Balloon Dilation Catheter (DIOR), Paclitaxel-Eluting Balloon (Bingo)
- Where
- 13 sites in China
- Volunteers
- 220 people
- Sponsor
- CCRF Inc., Beijing, China
Acute Coronary Syndrome, Percutaneous Coronary Intervention
Registry of Coronary Artery Ill Patients With Platelet Test Results
ONASSIST is a registry of coronary ill patients who have had a functional test measuring anti-platelet effect and/or a genetic profile of response to anti-platelet drugs.
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Myocardial Infarction
- Trial name
- ONASSIST (NCT02762162)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Action, France
CHD - Coronary Heart Disease, Percutaneous Coronary Intervention
Optical Coherence Tomography Guided Percutaneous Coronary Intervention for Drug-eluting In-stent Restenosis
This study is a prospective, registry trial aimed to compare the clinical and angiographic outcomes of OCT-guided and angiography-guided PCI in patients with coronary DES-ISR.
- Conditions
- CHD - Coronary Heart Disease, Percutaneous Coronary Intervention, In-stent Restenosis
- Trial name
- NCT03809754
- Testing
- Percutaneous Coronary Intervention under OCT, Percutaneous Coronary Intervention under Angiography
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Chinese PLA General Hospital
Percutaneous Coronary Intervention
Randomized Controlled Trials of Electro-acupuncture Effects on Perioperative Anxiety in Patients Treated With PCI
Randomized Controlled Trials of Electro-acupuncture Effects on Perioperative Anxiety in Patients Treated with PCI
- Trial name
- NCT03789344
- Testing
- acupuncture, Psychotherapy, blank control
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Huan Wang, MD
Erythrocyte Transfusion, Percutaneous Coronary Intervention
Bare Metal Stents and Drug Eluting Stents in Patients Who Underwent Blood Transfusion
Retrospective cohort study of Korean National Healthcare Insurance Database. To investigate clinical outcomes of bare metal stents versus drug eluting stents in patients who underwent periprocedural red blood cell transfusion.
- Conditions
- Erythrocyte Transfusion, Percutaneous Coronary Intervention, Revascularization
- Trial name
- TFPCI2 (NCT03788148)
- Testing
- Stent, red blood cell transfusion
- Where
- South Korea
- Volunteers
- 28,322 people
- Sponsor
- Samsung Medical Center
Platelet Aggregation Inhibitors, Hydroxymethylglutaryl-coa Reductase Inhibitors
The Compliance of DAPT and Statins on Clinical Outcomes in Percutaneous Coronary Intervention Patients
A nationwide retrospective cohort study. To investigate the real world medication compliance and the relation with clinical outcomes.
- Conditions
- Platelet Aggregation Inhibitors, Hydroxymethylglutaryl-coa Reductase Inhibitors, Compliance, Medication, Adherence, Medication
- Trial name
- CPPCI (NCT03785509)
- Testing
- DAPT, Statin
- Where
- South Korea
- Volunteers
- 47,291 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome, Percutaneous Coronary Intervention
Effectiveness of Artificial Intelligent Based mHealth System to Reduce ACS Patients Bleeding Events After PCI
The present study was designed to observe the effectiveness of artificial intelligent based mHealth system(Chronic disease management system) to reduce bleeding events in ACS patients undergoing PCI.
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Bleeding
- Trial name
- NCT03738930
- Testing
- AI based mHealth system
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Chinese PLA General Hospital
Acute Coronary Syndrome, Percutaneous Coronary Intervention
A Pharmacodynamic Study of a Personalized Strategy for P2Y12 Inhibition Versus Ticagrelor in Reducing Ischemic and Bleeding Risk
In patients with heart attacks, the treatment of choice is to restore blood flow with percutaneous coronary intervention (PCI) (use of stents (metal meshes) to open blockages).
- Trial name
- RAPID MANAGE (NCT02044146)
- Testing
- Ticagrelor, Prasugrel, Clopidogrel
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Percutaneous Coronary Intervention
Contemporary Clinical Treatment and Long-term Outcomes in Patient With Coronary Chronic Total Occlusion
In order to know more about contemporary clinical treatment ,epidemiological characteristics, and long-term outcomes in patients with Coronary Chronic Total Occlusion（CTO）in China, the study through collecting and effective…
- Trial name
- PCI (NCT03614559)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Myocardial Infarction, Percutaneous Coronary Intervention
Effects of Intracoronary Prourokinase on the Coronary Flow During Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction
The purpose of this study is to determine whether intracoronary selective thrombolysis are more effective than tirofiban on the coronary flow during primary percutaneous coronary intervention for the acute myocardial infarction.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Thrombolytic Therapy
- Trial name
- ERUPTION (NCT02131220)
- Testing
- Prourokinase, Tirofiban, normal saline
- Where
- China
- Volunteers
- 362 people
- Sponsor
- Fudan University
Atrial Fibrillation, Percutaneous Coronary Intervention
Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)
The main objective of this study is to compare a Dual Antithrombotic Therapy (DAT) regimen of 110mg dabigatran etexilate b.i.d. plus clopidogrel or ticagrelor (110mg dabigatran etexilate (DE) DAT) and 150mg dabigatran etexilate…
- Trial name
- NCT02164864
- Testing
- Dabigatran Etexilate 110mg, Warfarin 3mg, Aspirin
- Where
- 421 sites in United States, Argentina and 39 more
- Volunteers
- 2,725 people
- Sponsor
- Boehringer Ingelheim
Myocardial Infarction, Percutaneous Coronary Intervention
Text Message Intervention to Improve Cardiac Rehab Participation
Cardiac rehabilitation (CR) is strongly recommended for patients with coronary heart disease. However, patient enrollment and completion of cardiac rehabilitation is low.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery, Heart Valve Repair or Replacement
- Trial name
- NCT03346278
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Washington
Percutaneous Coronary Intervention
Comparison of Anticoagulation for All-comers Undergoing Percutaneous Coronary Revascularization Trial
The purpose of this trial is to determine whether bivalirudin is non-inferior to unfractionated heparin in patients with stable angina, unstable angina, or non-ST segment elevation myocardial infarction undergoing percutaneous…
- Trial name
- CALIFORNIA (NCT02448550)
- Testing
- Bivalirudin, Unfractionated heparin
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Kaiser Permanente
Percutaneous Coronary Intervention
Exploring the Volume-Outcome Relationship for PCI Procedures Undertaken in a UK Context: A NICOR Study
The relationship between annual procedural volume and patient outcome remains a debated issue in the field of interventional medicine.
- Trial name
- NCT02184949
- Testing
- Percutaneous Coronary Intervention, Primary Percutaneous Coronary Intervention
- Where
- United Kingdom
- Volunteers
- 427,467 people
- Sponsor
- University College, London