Clinical trials: Percutaneous Coronary Intervention Patients
Myocardial Infarction Complicated With Cardiogenic Shock
Adjunctive Mild Hypothermia Therapy to Primary Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction Complicated With Shock: A Feasibility Study
The purpose of this study is evaluate the safety and feasibility of mild therapeutic hypothermia (TH) during and 12 hours after primary percutaneous coronary intervention for acute myocardial infarction complicated with shock
- Trial name
- NCT00846222
- Testing
- Hypothermia
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Assaf-Harofeh Medical Center
Coronary Artery Disease, Left Main Coronary Artery Disease
IVUS VS CAG Guided PCI for Patients With LMB Lesion
To compare the 3 - year clinical follow - up results of patients with left main bifurcation lesions treated by intravascular ultrasound(IVUS) - guided and coronary angiography(CAG) - guided percutaneous coronary…
- Trial name
- Infinite (NCT04072003)
- Testing
- intravascular ultrasound (IVUS), coronary angiography
- Volunteers
- 616 people
- Sponsor
- Shanghai Zhongshan Hospital
Hypertension, Dyslipidemia
Evaluation of the Effectiveness and Safety of Rozetel Tablet in Patients After PCI: A Multi-Center Observational Study
The purpose of this study is to evaluate the effectiveness and safety of the investigational drug on blood pressure and LDL cholesterol control during the observation period in patients who have undergone percutaneous coronary…
- Trial name
- NCT07084246
- Where
- South Korea
- Volunteers
- 1,563 people
- Sponsor
- GC Biopharma Corp
Acute Myocardial Infarction, Phase I Cardiac Rehabilitation
The Impact of Phase I Cardiac Rehabilitation on the Prognosis of AMI Patients After PCI
Previous research has confirmed that patients undergoing percutaneous coronary intervention (PCI) can benefit from cardiac rehabilitation programs.
- Trial name
- AID (NCT06406218)
- Testing
- Phase I Cardiac Rehabilitation Exercise Training
- Where
- China
- Volunteers
- 1,100 people
- Sponsor
- Han Yaling, MD
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Sweden Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01667003
- Where
- 8 sites in Sweden
- Volunteers
- 406 people
- Sponsor
- Biotronik ApS
Ischemic Cardiomyopathy
Chronic, Low Dose Erythropoetin Beta in Ischemic Cardiomyopathy
The study is testing the hypothesis, that the application of low dose erythropoetin beta (35 I.E./kg BW/week) for 6 months following successful coronary revascularization by PCI improves left ventricular remodeling as assessed by…
- Trial name
- EPOHeart (NCT00568542)
- Testing
- erythropoetin beta
- Where
- 2 sites in Germany
- Volunteers
- 28 people
- Sponsor
- Charite University, Berlin, Germany
Coronary Artery Disease, Depression
The Recovery of Cardiovascular Patients With Depression
Cardiovascular disease increases the risk of depression and vice versa. Many cardiovascular patients are subjected to percutaneous coronary intervention (PCI).
- Conditions
- Coronary Artery Disease, Depression, Cardiovascular Diseases
- Trial name
- NCT03841474
- Testing
- Psychiatric treatment with sertraline, Psychiatric treatment with escitalopram
- Where
- Croatia
- Volunteers
- 150 people
- Sponsor
- Klinički Bolnički Centar Zagreb
ST-segment Elevation Myocardial Infarction (STEMI)
Thrombus Aspiration in STEMI Patients With High Thrombus Burden
This is a prospective, multicenter, open-label, randomized, controlled, parallel group study, in which ST-segment Elevation Myocardial Infarction (STEMI) patients with high thrombus burden(TIMI thrombus grade ≥3) are included.
- Trial name
- NCT04212494
- Testing
- Thrombus aspiration, PCI Alone
- Where
- 50 sites in China
- Volunteers
- 3,838 people
- Sponsor
- Guangdong Provincial People's Hospital
Acute Coronary Syndrome
Ticagrelor and Eptifibatide Bolus-Only Versus Ticagrelor and Eptifibatide Bolus Plus Abbreviated Infusion
This purpose of this study is to measure platelet response to ticagrelor and eptifibatide bolus-only compared with ticagrelor and eptifibatide bolus plus 2-hour infusion administrated after cardiac catheterization in patients…
- Trial name
- NCT01919723
- Testing
- Ticagrelor, Eptifibatide
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- University of Alabama at Birmingham
Insulin Resistance and PCI
Impact of Acute Insulin Resistance on Myocardial Blush in Non- Diabetic Patients Undergoing Primary Percutaneous Coronary Intervention
Full myocardial reperfusion with restoration of coronary microcirculatory function (CMF) is a therapeutic goal in ST-segment elevation myocardial infarction (STEMI).1 Despite the success of primary percutaneous coronary…
- Trial name
- NCT04651842
- Testing
- PCI
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Assiut University
Coronary Artery Disease
Ranolazine Loading to Prevent PCI-induced Myocardial Injury
It has previously been shown that pretreatment with ranolazine 1,000 mg twice daily for 7 days can significantly reduce procedural myocardial injury in elective percutaneous coronary intervention (PCI).
- Trial name
- TWILIGHT (NCT01491061)
- Testing
- Ranolazine
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Heart Failure, Myocardial Infarction
Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack
When a patient has a heart attack, a blockage occurs in a coronary artery that delivers oxygen to the heart muscle. The heart muscle may weaken, causing heart failure.
- Trial name
- RESUS-AMI (NCT01438086)
- Testing
- mecasermin, 0.9% sodium chloride injection
- Where
- 2 sites in Ireland, Netherlands
- Volunteers
- 47 people
- Sponsor
- University College Cork
Three Vessel Coronary Disease
Long-Term Outcomes in Patients With Three-Vessel Disease
The long-term outcome of coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), and medical therapy (MT) alone for triple-vessel disease (TVD) patients is controversial.
- Trial name
- NCT05007054
- Testing
- PCI or CABG
- Where
- China
- Volunteers
- 4,300 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Primary Percutaneous Coronary Intervention
Prognostic Value of the CALLY Index in Patients Undergoing Primary PCI
This study aims to evaluate the relationship between the admission CALLY index and short-term adverse outcomes in STEMI patients undergoing PPCI.
- Trial name
- NCT07203573
- Volunteers
- 140 people
- Sponsor
- Assiut University
Coronary Artery Disease
Tailoring P2Y12 Inhibiting Therapy in Patients Requiring Oral Anticoagulation After PCI
Clopidogrel is the P2Y12 inhibitor of choice in PCI patients requiring OAC. However, concerns have been raised based on the notion that a considerable number of patients may have inadequate response to clopidogrel.
- Trial name
- SWAP-AC-2 (NCT04483583)
- Testing
- Ticagrelor 60mg, Clopidogrel
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Florida
Ischemic Heart Disease, Stenotic Coronary Lesion
RESOLUTE China RCT
The primary objective of this study is to evaluate the in-stent late lumen loss (LLL) at 9 months, defined as the difference between the post-procedure minimal lumen diameter (MLD) and the follow-up angiography MLD, of the…
- Conditions
- Ischemic Heart Disease, Stenotic Coronary Lesion, Cardiovascular Diseases, Arteriosclerosis
- Trial name
- R-China RCT (NCT01334268)
- Testing
- Taxus Liberte Paclitaxel-Eluting Coronary Stent System, Resolute Zotarolimus-Eluting Coronary Stent System
- Where
- 4 sites in China
- Volunteers
- 400 people
- Sponsor
- Medtronic Vascular
Acute Myocardial Infarction, Congestive Heart Failure
Nicorandil Study to Reduce Cardiac Death After Percutaneous Coronary Intervention (PCI) in Hemodialysis Patients
Survival after invasive coronary revascularization is worse in patients with chronic kidney disease than in those without it. The investigators aimed to examine whether oral administration of nicorandil, a hybrid of nitrate and…
- Trial name
- NCT00848562
- Testing
- Nicorandil
- Where
- Japan
- Volunteers
- 129 people
- Sponsor
- Toujinkai Hospital
Coronary Artery Disease, Aortic Valve Stenosis
Revascularization in Patients Undergoing Transcatheter Aortic Valve Implantation
The aim of this study is to evaluate the effect of routine FFR-guided complete revascularization with PCI compared to conservative management in patients with concomitant coronary artery disease who are undergoing TAVI.
- Conditions
- Coronary Artery Disease, Aortic Valve Stenosis, TAVI, PCI
- Trial name
- NOTION-3 (NCT03058627)
- Testing
- PCI
- Where
- 12 sites in Denmark, Finland and 2 more
- Volunteers
- 454 people
- Sponsor
- Thomas Engstrom
Coronary Artery Lesion
ABSORB Bioresorbable Scaffold vs. Xience Metallic Stent for Prevention of Restenosis in Patients at High Risk of Restenosis
The primary objectives of this trial are: In patients at high-risk for restenosis, To assess non-inferiority of the everolimus-eluting bioresorbable scaffold (BRS) to the everolimus eluting cobalt chromium metallic stent (EES) in…
- Trial name
- Compare Absorb (NCT02486068)
- Testing
- ABSORB scaffold, Xience
- Where
- 44 sites in Belgium, Czechia and 7 more
- Volunteers
- 1,670 people
- Sponsor
- European Cardiovascular Research Center
Acute Myocardial Infarction
Correlation of Blood Serum Renalase and Microcirculation Obstruction in Patients with Acute Myocardial Infarction After Primary Percutaneous Coronary Intervention
This research will explore the association between blood serum renalase and microcirculation obstruction in patients with acute myocardial infarction (AMI) after primary percutaneous coronary intervention (PCI).
- Trial name
- NCT06669520
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University