Clinical trials: Percutaneous Coronary Revascularization
Myocardial Infarction, Acute Coronary Syndromes
Thrombectomy in ST Elevation Myocardial Infarction, an Individual Patient Meta-analysis
During primary percutaneous coronary intervention, distal embolization of thrombus and impaired microvascular perfusion has been associated with an increased mortality.
- Trial name
- NCT02552407
- Testing
- Manual Aspiration Thrombectomy
- Volunteers
- 18,000 people
- Sponsor
- Population Health Research Institute
Coronary Artery Disease, Stenosis Coronary
SPAGO: Sirolimus Paclitaxel Angiographic Gain Objective
The objective of the study is to compare angiographic outcomes of Selution sirolimus coated balloon (MedAlliance) versus SeQuent Please Neo paclitaxel coated balloon (Bbraun) for the treatment of de novo coronary artery lesions…
- Conditions
- Coronary Artery Disease, Stenosis Coronary, Coronary Artery Lesion, Percutaneous Coronary Intervention
- Trial name
- SPAGO (NCT06373601)
- Testing
- sirolimus-eluting balloon (Selution), paclitaxel-eluting balloon (SeQuent Please Neo)
- Where
- 10 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS
Coronary Artery Disease, Diabetes Mellitus, Type 2
Platelet Inhibition of Ticagrelor Versus Clopidogrel in Type 2 Diabetic Patients After Elective Percutaneous Coronary Intervention
This will be a single-center, randomized, open-label, active-controlled, parallel-group study to investigate the platelet inhibition of Ticagrelor versus Clopidogrel with acetylsalicylic acid (ASA) as background therapy in…
- Trial name
- PLATIDE-PCI (NCT02748330)
- Testing
- Ticagrelor, Clopidogrel, Aspirin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
ST Segment Elevation Myocardial Infarction, Primary Percutaneous Coronary Intervention
Prevention of Coronary Slow Flow or No-Reflow During PPCI in Patients With Acute STEMI
Primary percutaneous coronary intervention (PPCI) is the gold standard of treatment of ST segment elevation myocardial infarction (STEMI).Slow flow / no-reflow phenomenon following PPCI in STEMI patients has been a serious and…
- Trial name
- NOSLOWFLOW-Ⅰ (NCT03406819)
- Testing
- Nitroprusside Sodium, Tirofiban Hydrochloride, Heparinized saline
- Where
- 28 sites in China
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
PRU(Platelet Reactivity Unit), APT(Antiplatelet Therapy)
Platelet Reactivity (High On-Treatment Platelet Reactivity) as Guidance for APT (Antiplatelet Therapy) Adjustment After PCI (Percutaneous Coronary Intervention)
Since thrombus formation is a very complex procedure in vivo, platelet function testing methods in vitro might only reflect the degree of inhibition of platelet from a certain level, which do't reflect the functional status of…
- Conditions
- PRU(Platelet Reactivity Unit), APT(Antiplatelet Therapy), HOTPR(High on Treat Platelet Reactivity)
- Trial name
- NCT02101411
- Testing
- PRU(Platelet reactivity unit)
- Where
- Taiwan
- Volunteers
- 334 people
- Sponsor
- Taipei City Hospital
ST Elevation Myocardial Infarction, No-Reflow Phenomenon
Rivaroxaban for Slow Coronary Flow After PCI in STEMI
The goal of this clinical trial is to learn if drug Rivaroxaban works to improve slow flow in STEMI patients after PCI in adults. It will also learn about the safety of drug Rivaroxaban.
- Trial name
- NCT07195812
- Testing
- Dual Antiplatelet (DAPT) Therapy, Rivaroxaban
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ischemic Cardiomyopathy
RestoratIon of Myocardial Function by PeRcutaneous cOronary interVEntion in Patients With Ischemic CardioMyoPathy
To compare the effects of physiology- and imaging-guided PCI combined with optimal medical therapy (OMT) versus OMT alone on the recovery of left ventricular systolic function in patients with ischemic cardiomyopathy and…
- Trial name
- IMPROVE-ICMP (NCT06930092)
- Testing
- Physiology-and imaging-guided PCI, Optimal medical treatment
- Where
- South Korea
- Volunteers
- 158 people
- Sponsor
- Seoul National University Hospital
NSTEMI
The Problem of Incomplete Myocardial Revascularization in Percutaneous Coronary Intervention in Patients With NSTEMI
The study included all patients admitted to the intensive care unit of the district hospital and sent to the angiographic Department for diagnosis and performance of PCI with a diagnosis of NSTEMI, including myocardial infarction…
- Trial name
- CONTRAST (NCT04490928)
- Where
- Russia
- Volunteers
- 139 people
- Sponsor
- National Research Center for Preventive Medicine
Acute Myocardial Infarction, Percutaneous Coronary Intervention
CardiOvascular Risk and idEntificAtion of Potential High-risk Population in Acute Myocardial Infarction II (COREA-AMI II)
This study is intended to provide contemporary data on the residual cardiovascular risk in all consecutive patients with acute myocardial infarction, especially in patients who survived stably within one-year after percutaneous…
- Conditions
- Acute Myocardial Infarction, Percutaneous Coronary Intervention, Major Adverse Cardiovascular Events, Bleeding
- Trial name
- NCT02806102
- Testing
- Percutaneous coronary intervention, Dual-antiplatelet therapy
- Where
- 2 sites in South Korea
- Volunteers
- 13,000 people
- Sponsor
- Seoul St. Mary's Hospital
Acute Coronary Syndrome, Myocardial Infarction
Outcome of Longterm Antithrombotic Therapy in Acute Coronary Syndrome Patients
This observational study will based on the Register of Information and Knowledge About Swedish Heart Intensive Care Admissions (RIKS-HIA) and the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) which since 2009 are…
- Trial name
- NCT01623700
- Where
- Sweden
- Volunteers
- 78,000 people
- Sponsor
- Uppsala University
Angioplasty, Transluminal, Percutaneous Coronary
A Study Comparing the Efficacy and Safety of Abciximab, an Anti-Platelet Therapy, in Combination With Two Different Heparin Regimens in Patients Undergoing Percutaneous Coronary Intervention.
The purpose of this study is to compare the safety and effectiveness of abciximab, an anti-platelet therapy, versus placebo in patients undergoing percutaneous coronary intervention when administered in combination with two…
- Trial name
- NCT00269880
- Testing
- Heparin, Abciximab
- Volunteers
- 2,792 people
- Sponsor
- Centocor, Inc.
PCI
Prognostic Role of Lipoprotein(a) in Elective Percutaneous Coronary Revascularization
The study investigates the role of Lipoprotein(a) [Lp(a)] levels in predicting cardiovascular risk and adverse events in patients undergoing elective percutaneous coronary intervention (PCI).
- Trial name
- NCT07197242
- Volunteers
- 156 people
- Sponsor
- Assiut University
Coronary Artery Disease
The Percutaneous Coronary Intervention Registry in University Medical Center of Ho Chi Minh City
This is a hospital-based registry study that will be to describe clinical and paraclinical features, procedural-related characteristics, short and long-term outcomes, hospital costs of patients undergoing percutaneous coronary…
- Trial name
- UMC-PCI (NCT06071741)
- Testing
- Percutaneous Coronary Intervention
- Where
- Vietnam
- Volunteers
- 3,600 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques
Effectiveness of Interventional Therapy for Non-Flow-Limiting Vulnerable Plaques
The aim of this clinical trial is to explore the optimal preventative treatment strategy for non-flow-limiting vulnerable plaques.
- Conditions
- Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques, Thin-cap fIbroatheroma, Acute Coronary Syndromes (ACS)
- Trial name
- NCT06855537
- Testing
- PCI strategy, OMT strategy
- Where
- China
- Volunteers
- 2,190 people
- Sponsor
- Beijing Anzhen Hospital
Arterial Occlusive Diseases, Myocardial Ischemia
RESOLUTE Japan - The Clinical Evaluation of the MDT-4107 Drug-Eluting Coronary Stent
The objective of the study is to verify the safety and efficacy of the MDT-4107 Drug-Eluting Coronary Stent for the treatment of de novo lesions in native coronary arteries.
- Conditions
- Arterial Occlusive Diseases, Myocardial Ischemia, Cardiovascular Diseases, Coronary Artery Disease
- Trial name
- RJ (NCT00927940)
- Testing
- MDT-4107 Drug Eluting Stent
- Where
- 14 sites in Japan
- Volunteers
- 100 people
- Sponsor
- Medtronic Vascular
Acute Myocardial Infarction, Cardiovascular Diseases
Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE
The goal of this randomized, double-blind, placebo-controlled clinical trial is to investigate the immunological effects of influenza vaccination outside of the influenza season on arterial inflammation in patients with a recent…
- Conditions
- Acute Myocardial Infarction, Cardiovascular Diseases, Inflammatory Response
- Trial name
- ELIMINATE (NCT06336317)
- Testing
- Influenza vaccine
- Where
- 3 sites in Denmark, Sweden and 1 more
- Volunteers
- 90 people
- Sponsor
- Region Örebro County
Diabetes Mellitus, Coronary Artery Disease
Randomized Trial Comparing Two Sirolimus-Eluting Stents in Diabetes Mellitus
Randomized, controlled, blind, single-center and non-inferiority clinical trial to compare the target lesion failure (TLF) at 12 months in patients with diabetes mellitus who underwent percutaneous coronary intervention with an…
- Conditions
- Diabetes Mellitus, Coronary Artery Disease, Acute Coronary Syndrome
- Trial name
- INC-DM (NCT04660240)
- Testing
- Abluminus Sirolimus Eluting Stent System (ASES), Orsiro Sirolimus Eluting Coronary Stent System (OSES)
- Where
- Mexico
- Volunteers
- 860 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Coronary Heart Disease
Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart Disease
The purpose of this study is to compare the efficacy between two lipid lowering treatments, rosuvastatin (10-40 mg) and atorvastatin (20-80 mg) in reducing low-density lipoprotein cholesterol (LDL-C) levels after 16 weeks of…
- Trial name
- NCT00235950
- Testing
- Rosuvastatin or atorvastatin or simvastatin and clopidogrel
- Where
- 18 sites in Sweden
- Volunteers
- 255 people
- Sponsor
- AstraZeneca
ST Elevation Myocardial Infarction, Coronary Artery Disease
Distal Versus Conventional Transradial Artery Access for Coronary Catheterization in Patients With STEMI
Recently, a novel distal transradial, through anatomical snuffbox, approach has been proposed for undertaking percutaneous coronary angiography and interventions.
- Conditions
- ST Elevation Myocardial Infarction, Coronary Artery Disease, Distal Transradial Artery, Transradial Artery
- Trial name
- DR-STEMI (NCT05605288)
- Testing
- Coronary angiography +/- percutaneous coronary intervention
- Where
- 3 sites in Belgium, Greece and 1 more
- Volunteers
- 554 people
- Sponsor
- University Hospital of Patras
Myocardial Infarction
A Clinical Evaluation of Everolimus Eluting Coronary Stents in the Treatment of Patients With ST-segment Elevation Myocardial Infarction: EXAMINATION Study
This study is a prospective, randomized controlled, single blind, two-arm, multi center clinical evaluation. A total of 1500 patients will be enrolled in the study.
- Trial name
- NCT00828087
- Testing
- Everolimus Eluting Coronary Stent System, cobalt chromium balloon expandable stent ( non drug eluting stent Arm)
- Where
- 11 sites in Italy, Netherlands and 1 more
- Volunteers
- 1,504 people
- Sponsor
- Spanish Society of Cardiology