Clinical trials: Percutaneous Tumor Ablation
Hepatocellular Carcinoma (HCC)
Computer Guided Microwave Liver Ablation
The goal of this clinical trial is to learn if the intraoperative use of a computer guidance software can improve the success of liver tumor ablation in adults.
- Trial name
- MWA Sim (NCT07226869)
- Testing
- Computer-Assisted Microwave Liver Ablation
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- NE Scientific INC
Bone Cancer Metastatic
A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy
The objective of this study is to evaluate real-world outcomes (e.g., pain, patient reported outcomes, skeletal related events, healthcare utilization, etc.) in patients treated with both percutaneous ablation and palliative…
- Trial name
- TRIBUTE (NCT06859801)
- Testing
- Percutaneous Ablation, Radiation Therapy
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Society of Interventional Oncology
Cancer
Analysis of Percutaneous Ablations for Cancer Treatment
This is a study involving patients with cancer who are referred by their treating physician for percutaneous locoregional therapies.
- Trial name
- NCT01563679
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Emory University
Renal Cell Cancer
Percutaneous Tumor Ablation Vs Partial Nephrectomy for Small Renal Mass: the Impact of Histologic Variant and Tumor Size
The aim, of this study is to investigate recurrence rates in patients with T1 renal cell carcinoma (RCC) undergone partial nephrectomy (PN), radiofrequency ablation (RFA) or cryoablation (Cryo).
- Trial name
- CRYO-BO-2021 (NCT06829888)
- Volunteers
- 955 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hepatocellular Carcinoma
Neoadjuvant Atezo, Adjuvant Atezo + Beva Combined With RF Ablation of Small HCC: a Multicenter Randomized Phase II Trial
Following the results of study IMbrave150, the combination Atezolizumab + Bevacizumab is a promising treatment option for patients with HCC.
- Trial name
- AB-LATE02 (NCT04727307)
- Testing
- Atezolizumab (neoadjuvant), Percutaneous Radiofrequency, Bevacizumab (adjuvant)
- Where
- 19 sites in France
- Volunteers
- 202 people
- Sponsor
- University Hospital, Montpellier
Hepatocellular Carcinoma
A Study to Evaluate Autologous CIK Cells in Patients With Hepatocellular Carcinoma After TACE, PEIT or RFA
A Phase I/II, Open Label Study to Evaluate the Safety and Efficacy of Autologous Cytokine-Induced Killer (CIK) Cell for Patients with Hepatocellular Carcinoma (HCC) after Transarterial Chemoembolization (TACE), Percutaneous…
- Trial name
- NCT03124498
- Testing
- CIK Cell
- Volunteers
- 55 people
- Sponsor
- Chuan An Biotechnology Co., Ltd.
Unrecognized Condition
Air Dissection in Percutaneous Radiofrequency Ablation of T1a Renal Cell Carcinoma
The investigators aimed to evaluate the feasibility and safety of using ambient air to protect against thermal injury during RadioFrequency Ablation (RFA) for Renal Cell Carcinoma (RCC) based on data from cases at their institute.
- Trial name
- NCT03395379
- Testing
- RFA
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Metastatic Cancer, Pain
Radiofrequency Ablation in Treating Patients With Bone Metastases
RATIONALE: Radiofrequency ablation may be effective in decreasing pain from bone metastases. PURPOSE: Phase I/II trial to study the effectiveness of radiofrequency ablation in decreasing pain in patients who have bone metastases.
- Conditions
- Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- ACRIN-6661 (NCT00026247)
- Testing
- pain therapy, radiofrequency ablation
- Where
- 8 sites in United States
- Volunteers
- 66 people
- Sponsor
- American College of Radiology Imaging Network
Cancer
Safety And Accuracy Study Of The Actisight™ Needle Guidance System In Patients Undergoing CT-Guided Procedures
This will be a prospective, single-arm, single-center, open-label study to evaluate the preliminary safety and accuracy of the ActiSight™ Needle Guidance System in patients undergoing CT-guided percutaneous aspiration and RF…
- Trial name
- NCT01040884
- Testing
- ActiSight Needle Guidance System
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- ActiViews Ltd.
Hepatocellular Carcinoma
Neoadjuvant and Adjuvant Lenvatinib in HCC Patients Treated by Percutaneous Ablative
Percutaneous ablation (PA) is the only non-surgical curative treatment of hepatocellular carcinoma (HCC). Due to its excellent tolerance, particularly in patients with portal hypertension or bearing comorbidities, it now…
- Trial name
- LENVABLA (NCT05113186)
- Testing
- Lenvatinib Pill
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hepatocellular Carcinoma, Hepatitis C
HCV Related Hepatocellular Carcinoma Recurrence After Directly Acting Antivirals: A Randomized Controlled Trial
Data regarding hepatocellular carcinoma (HCC) recurrence after directly acting antivirals (DAAs) given for hepatitis C virus treatment are contradictory.
- Conditions
- Hepatocellular Carcinoma, Hepatitis C, Neoplasm Recurrence, Treatment Complication
- Trial name
- RCT (NCT04653818)
- Testing
- Velpatasvir/Sofosbuvir
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Alexandria University
Liver Tumors, HCC - Hepatocellular Carcinoma
Needle-based Percutaneous Ablation of Liver Tumors.
The goal of this clinical trial is to learn if INT001 can ablate liver tumors in adults in an outpatient setting. It will also help us learn about the safety of INT001. The main questions it aims to answer are: 1.
- Conditions
- Liver Tumors, HCC - Hepatocellular Carcinoma, Metastatic Liver Tumor
- Trial name
- NCT06689670
- Testing
- Needle based delivery of INT001 into liver tumors under real-time image guidance
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- inTumo Therapeutics, Inc.
HCC
Intraprocedural Assessment of Ablation Margins Using Computed Tomography Co-registration in Primary Liver Tumor Treatment With Percutaneous Ablation
A pre- and postablation scan will be made intraprocedurally to investigate the feasibility of intraprocedural ablation verification assessment using coregistration software
- Trial name
- IAMCOMPLETE (NCT04123340)
- Testing
- Additional intraprocedural pre-ablation CT-scan
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Leiden University Medical Center
Carcinoma, Hepatocellular
Comparison Between Radiofrequency Versus Ethanol Injection for the Treatment of Hepatocellular Carcinoma
Ethanol injection has been for many years the standard approach as percutaneous treatment of non-surgical early hepatocellular carcinoma in cirrhotic patients.
- Trial name
- NCT00355212
- Testing
- percutaneous ablation of hepatocellular carcinoma
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Hepatitis B, Hepatocellular Carcinoma
The Risk of Exacerbation of Chronic Hepatitis B After Percutaneous Radiofrequency Ablation of Hepatocellular Carcinoma
This study aim to find out the risk of exacerbation of chronic hepatitis B after percutaneous radiofrequency ablation (RFA) or hepatectomy for HCC, and it's effect to treatment outcome.
- Trial name
- HBV-HCC (NCT00720668)
- Testing
- radiofrequency ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Renal Cell Carcinoma
Comparison Between Partial Nephrectomy and Ablation for Renal Tumor
The therapeutic effectiveness of ultrasound guided cooled-probe microwave ablation and laparoscopic partial nephrectomy on T1a renal cell carcinoma is compared to find a better approach for renal tumor.
- Trial name
- NCT03094949
- Testing
- Partial Nephrectomy, microwave ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Breast Cancer
Percutaneous Cryoablation of Low-risk Early Breast Cancer
Expand the current evidence base regarding percutaneous cryoablation of early-stage, low-risk breast tumors, integrated into the standard therapeutic pathway with well-defined follow-up data, as well as data on quality of life.
- Trial name
- PRECICE (NCT06300125)
- Testing
- Cryoablation
- Where
- Italy
- Volunteers
- 234 people
- Sponsor
- European Institute of Oncology
Desmoid Tumor, Aggressive Fibromatoses
Patient-reported Outcomes Following Percutaneous Ablation of Desmoid Tumors
This study will evaluate patient-reported outcomes before and after percutaneous ablation of desmoid tumors. Adult participants undergoing ablation for desmoid tumor will complete surveys pre and post procedure to assess symptom…
- Trial name
- NCT07755176
- Testing
- Desmoid tumor ablation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Thyroid Nodule, Thyroid Goiter
Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System
The primary objective of this study is to reproduce in a multi-center study results obtained during the feasibility First-In-Human (FIH) study with Prof.
- Conditions
- Thyroid Nodule, Thyroid Goiter, Ablation
- Trial name
- PRECISE-BTN (NCT07287176)
- Testing
- nPulse Vybrance Percutaneous Electrode System
- Where
- 3 sites in United States
- Volunteers
- 103 people
- Sponsor
- Pulse Biosciences, Inc.
Liver Cancer
Radiofrequency Ablation in Treating Patients With Liver Cancer and Cirrhosis
RATIONALE: Radiofrequency ablation uses a high-frequency, electric current to kill tumor cells. CT-, MRI-, or ultrasound-guided radiofrequency ablation may be an effective treatment for liver cancer and cirrhosis.
- Trial name
- ACRIN-6673 (NCT00132041)
- Testing
- radiofrequency ablation
- Where
- 18 sites in United States
- Volunteers
- 51 people
- Sponsor
- American College of Radiology Imaging Network