Clinical trials: Perfusion
Controlled Hypotension for Nasal Surgeries
Effects of Different MAP Targets on Ocular Perfusion and Optic Nerve Microvasculature During Rhinoplasty
This randomized controlled trial aims to evaluate the effects of two different mean arterial pressure (MAP) targets during controlled hypotension on ocular perfusion and optic nerve head microvasculature in patients undergoing…
- Trial name
- NCT07832305
- Testing
- Lower MAP Target Strategy (50-60 mmHg), Higher MAP Target Strategy (60-70 mmHg)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hitit University
Organ Perfusion Determined by Using NIRS Post Transcatheter PDA Occlusion or Medical Closure of PDA
PDA Occlusion Using NIRS
Our study will be a prospective observational study of all patients in the Norton Children's Hospital NICU (Neonatal Intensive Care Unit) who undergo a transcatheter PDA occlusion or medical closure of PDA to compare the two…
- Trial name
- NCT06359522
- Testing
- NIRS monitor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Louisville
Aortocoronary Bypass
Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion
Linear flow during cardiopulmonary bypass (CPB) frequently induces renal damage. We will evaluate whether automatic intra-aortic balloon pump (IABP) induce pulsatile perfusion preserves renal function in patients undergoing…
- Trial name
- NCT00454428
- Testing
- pulsatile intra-aortic balloon pump
- Where
- Italy
- Sponsor
- University of Catanzaro
Stage I Renal Cell Cancer, Stage II Renal Cell Cancer
Perfusion Magnetic Resonance Imaging in Diagnosing Patients With Kidney Tumors
This pilot clinical trial studies perfusion magnetic resonance imaging in diagnosing patients with kidney tumors. Diagnostic procedures, such as perfusion magnetic resonance imaging, may help find and diagnose kidney tumors and…
- Conditions
- Stage I Renal Cell Cancer, Stage II Renal Cell Cancer, Stage III Renal Cell Cancer, Stage IV Renal Cell Cancer
- Trial name
- NCT02526511
- Testing
- Arterial Spin Labeling Magnetic Resonance Imaging, Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Rutgers, The State University of New Jersey
VLBW - Very Low Birth Weight Infant
Peripherel Perfusion Index to Predict Sepsis in Very Low Birth Weight Infants
To explore the predictive value of peripheral perfusion index in late onset sepsis of very low birth weight infants , obtain the threshold by observing the perfusion index of very low birth-weight infants within one month after…
- Trial name
- NCT05224921
- Testing
- Not applicable (cohort study)
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Children's Hospital of Fudan University
Heart Failure, Dilated Cardiomyopathy
Brain Function and Perfusion in Patients With Heart Failure
The investigators will evaluate the determinants of cerebral impairment in patients with non-ischemic heart failure compared to controls, and its relation to cognitive function.
- Conditions
- Heart Failure, Dilated Cardiomyopathy, Perfusion, Cognitive Impairment
- Trial name
- BRAIN-HF (NCT01756014)
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Stable Angina Pectoris, Coronary Artery Disease
Comprehensive Cardiac CT Versus Exercise Testing in Suspected Coronary Artery Disease (2)
Multi-center, randomized-controlled trial comparing a comprehensive cardiac CT protocol with standard stress testing in patients with stable chest pain complaints.
- Trial name
- CRESCENT2 (NCT02291484)
- Testing
- Cardiac CT scan
- Where
- 4 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Erasmus Medical Center
ST-Elevation Myocardial Infarction
Comparison of Intracoronary Versus Intravenous Abciximab in ST-segment Elevation Myocardial Infarction (CICERO)
The primary objective of this study is to investigate whether intracoronary bolus administration of abciximab is superior to intravenous bolus administration in improving myocardial perfusion in patients with ST-segment elevation…
- Trial name
- CICERO (NCT00927615)
- Testing
- abciximab
- Where
- Netherlands
- Volunteers
- 534 people
- Sponsor
- University Medical Center Groningen
Insemination, Artificial
Fallopian Tube Sperm Perfusion (FSP) Versus Intra-uterine Insemination (IUI) in Natural Cycle
The purpose of this study is to evaluate the efficacy of fallopian sperm perfusion (FSP) in comparison with standard intrauterine insemination (IUI) in natural cycle for couples with unexplained infertility or mild male factor.
- Trial name
- NCT00816387
- Testing
- Fallopian tube sperm perfusion, Intrauterine insemination using standard catheter
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- IRCCS Burlo Garofolo
Type 2 Diabetes Mellitus
Enhancement of Cerebral Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes
Our goal is to determine the acute effects of intranasal insulin on regional perfusion and cognition of older adults. We propose a pilot study to examine the effect of a single dose of intranasal insulin on regional…
- Trial name
- NCT01206322
- Testing
- Intranasal insulin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Coronary Artery Disease
Efficacy and Safety Study of Binodenoson in Assessing Cardiac Ischemia
Binodenoson (an experimental drug) and adenosine (an FDA-approved drug that is currently used by doctors) are used to increase blood flow to the heart just like when a person exercises on a treadmill.
- Trial name
- VISION-302 (NCT00944294)
- Testing
- binodenoson, adenosine
- Volunteers
- 419 people
- Sponsor
- Pfizer
Retinal Vein Occlusions
OCT in Retinal Vein Occlusions
Retinal blood vessel disease encompasses a wide variety of vision-threatening conditions. Of these conditions, retinal vein occlusions are the most common.
- Trial name
- NCT01992575
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Oregon Health and Science University
Endothelial Dysfunction, Hemolysis
CPB Prime Fluid Strategies to Preserve Mcirocirculatory Perfusion
Acute microcirculatory perfusion disturbances is common in critical illness and associated with higher morbidity and mortality. Recent findings by the investigators' group showed that microcirculatory perfusion is disturbed…
- Conditions
- Endothelial Dysfunction, Hemolysis, Fluid Overload
- Trial name
- PRIME (NCT05647057)
- Testing
- A: gelofusine + ringers, B: albumine + ringers, C: ringers + retrograde autologous priming
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Amsterdam UMC, location VUmc
Coronary Artery Disease
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
This a Phase 3, prospective, open-label, multicenter study of [15-O]-H2O injection for PET imaging of subjects with suspected CAD.
- Trial name
- NCT05134012
- Testing
- [O-15]-Water PET Myocardial Perfusion Imaging (MPI)
- Where
- 13 sites in United States, Canada and 4 more
- Volunteers
- 215 people
- Sponsor
- MedTrace Pharma A/S
Kidney Transplant Failure and Rejection
Using the Speckle Doppler to Quantify Blood Flow in Kidney and Pancreas Grafts
Kidney and Pancreas transplantation is considered the treatment of choice for many people with End Stage Renal Disease and Type 1 diabetes because quality of life and survival is often better after transplantation.
- Trial name
- NCT04202237
- Testing
- Speckle Doppler imaging, Blood sample
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Manchester University NHS Foundation Trust
Critical Limb Ischemia, Claudication, Intermittent
Pedal Acceleration Time (PAT) as a Measure of Foot Perfusion
To identify a correlation between Toe Brachial pressure Index (TBPI) and Acceleration time of the pedal vessels. The aim would then to use this data to design a clinical study assessing the relationship between PAT and wound…
- Trial name
- PAT (NCT06007469)
- Volunteers
- 50 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Heart Transplantation
Myocardial Perfusion Echocardiography to Detect Human Heart Transplant Rejection
The primary objective of this proposal is to show the efficacy of contrast enhanced ultrasonography in detecting heart transplant rejection in humans.
- Trial name
- NCT02300870
- Testing
- Optison
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Shock
BWH Critical Care Study of CareGuide for Evaluation of Emerging or Established Shock
This pilot study aims to examine the relationship between continuously measured CareGuide™ muscle oxygen saturation (SmO2), tissue pH and data provided from standard monitoring techniques during the care of subjects with…
- Trial name
- NCT03060369
- Testing
- CareGuide™ device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Myocardial Perfusion Imaging
Regadenoson vs Dipyridamole in Use as Pharmacological Stress Agent Before SPECT
Myocardial perfusion scintigraphy is to evaluate coronary perfusion as well as heart muscle function. This examination takes place in two stages, one imaging at rest and one after a cardiac stress caused.
- Trial name
- REDUCE (NCT03084562)
- Testing
- collect examination time, functional and clinical tolerability
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Technology
Evaluation of the IKORUS Technology in Patients Undergoing Major Abdominal Surgery
The goal of this observational substudy is to evaluate the feasibility, performance and behavior of the IKORUS (Advanced Perfusion Diagnostics, Villeurbanne, France), a new tissue perfusion device using urethral…
- Trial name
- NCT04187274
- Testing
- IKORUS technology
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Erasme University Hospital