Clinical trials: Peri-implant Bone Loss
Tooth Loss
Clinical Assessment of Dental Implant
Primary Endpoints : The implant survival and success rate of V3 and C1 implants will be compared. Implant success rate will be evaluated by measuring the peri-implant bone remodeling from baseline to 1 year post insertion.
- Trial name
- H2015-1 (NCT02591706)
- Testing
- MIS Implants
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Liege
Tooth Loss, Bone Loss, Alveolar
Immediate Implant Outcomes With and Without Bone Augmentation
To evaluate immediate implant placement feasibility and esthetic outcomes in severely damaged sockets that received simultaneously bone reconstruction (cortical bone shield) and implant placement versus intact sockets that needed…
- Conditions
- Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
- Trial name
- NCT05157009
- Testing
- implant placement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Dental Implant, Soft Tissue
Effect of Bone-related and Soft-tissue-related Variables on the Marginal Bone Loss of Platform-matched and Platform Switched Dental Implants
In this clinical trial the effect of the implant-abutment morphology (platform-switched vs platform matched) will be assessed in both soft tissue (soft tissue thickness) and hard tissue (marginal bone loss) outcomes.
- Conditions
- Dental Implant, Soft Tissue, Partial-edentulism, Bone Loss
- Trial name
- NCT05670340
- Testing
- Switched Prosthetic Profile, Matched Prosthetic Profile
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement
Silicate β-TCP vs Extended Sticky Bone for Peri-Implant Jumping Gap in Guided Immediate Implants: RCT
This randomized clinical trial compares three peri-implant jumping gap management approaches following fully guided immediate implant placement in the maxillary esthetic zone.
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Guided Immediate Implant Placement, Bone Grafting, Customized Healing Abutment
- Trial name
- JUMP-ESTHETIC (NCT07700706)
- Testing
- No Grafting, Silicate-Added β-TCP Putty, Extended Sticky Bone
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Edentulism, Dental Implantation, Endosseous
Subcrestal vs Juxtacrestal PRAMA Implants With Variable Necks
The goal of this clinical trial is to understand how different implant neck designs and placement depths affect the surrounding bone and peri-implant tissue (the tissue around a dental implant) in adults who need implants in the…
- Conditions
- Edentulism, Dental Implantation, Endosseous, Marginal Bone Loss, Periimplant Bone Loss
- Trial name
- NCT07107464
- Testing
- Short Neck Implant - Crestal Placement, Standard Neck Implant - 1 mm Subcrestal Placement, Long Neck Implant - 2 mm Subcrestal Placement
- Where
- Cuba
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Dental Implant, Marginal Bone Loss
Manual or Digitally Guided Surgical Technique for Replacing Single Tooth Edentulism by Means of Sub-crestally Placed Implants. A 3-year Parallel Randomized Clinical Study on Marginal Bone Levels Stability
The aim of the present prospective study was to investigate after a 2-year of follow-up any influence of the surgical technique, manual or digitally guided, on peri-implant marginal bone levels stability in implants placed 1 mm…
- Conditions
- Dental Implant, Marginal Bone Loss, Peri Implant Health, Supral Tissue Height
- Trial name
- NCT06250621
- Testing
- Implant placement
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- ASST Santi Paolo e Carlo
Bone Loss, Implant Complication
The Effects of Dis/Reconnection of Implant Abutments on Peri-implant Bone Levels
The aim of this study was to evaluate the effects of definitive abutment connection at the time of implant placement on peri-implant bone levels and soft tissue changes in posterior maxilla and mandible regions.
- Conditions
- Bone Loss, Implant Complication, Gingival Recession
- Trial name
- NCT04043286
- Testing
- Definitive abutment
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Implant Site Reaction
Assessment of Heat Generation From Low Speed Drilling Without Irrigation
ASSESSMENT OF LOW SPEED DRILLING WITHOUT IRRIGATION VERSUS CONVENTIONAL DRILLING WITH IRRIGATION REGARDING HEAT GENERATION AND PERI-IMPLANT MARGINAL BONE LOSS
- Trial name
- NCT03743545
- Testing
- low speed drilling without irrigation
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Bone Loss, Patient Satisfaction
Effect of Implant Position on Clinical Outcomes
the study aims to investigate the clinical influence of different implant locations; lateral incisor, canine, and first premolar areas; supporting 2-implant retained mandibular over-dentures with locator attachment on prosthesis…
- Trial name
- NCT06166316
- Testing
- overdenture retained by locator attachments.
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periimplant Bone Loss, Marginal Periimplant Bone Level
Changes on the Interproximal Bone Level on Direct Prostheses or With Intermediate Abutments
Study Title: Changes on the Interproximal marginal bone level after CAD-CAM designed bridges directly placed on bone-level implants, or with intermediate abutments. A Randomized Clinical Trial.
- Conditions
- Periimplant Bone Loss, Marginal Periimplant Bone Level, Periimplantitis
- Trial name
- NCT04369170
- Testing
- prosthesis connected directly to the implants, Intermediate abutment
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- University of Santiago de Compostela
Edentulous Jaw, Bone Loss, Alveolar
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Platelet concentrates obtained from blood have been used as regenerative biomaterials in periodontal surgery. Along with the migration and proliferation of osteogenic cells, platelets accelerate bone regeneration by increasing…
- Conditions
- Edentulous Jaw, Bone Loss, Alveolar, Resorption, Bone
- Trial name
- NCT04851002
- Testing
- Application of concentrated growth factor with dental implants, Application of advanced platelet rich fibrin with dental implants, Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muhammet Atilgan
Peri-implant Marginal Bone Loss, Peri-implant Bone Level
Influence of the Design of the Transmucosal Abutment on the Periimplant Bone Level
The objective of this study is to evaluate the radiographic changes on the marginal peri-implant bone level on bone level implants with a narrower transmucosal abutment, in comparison to the conventional abutment, both of 3mm…
- Conditions
- Peri-implant Marginal Bone Loss, Peri-implant Bone Level, Transmucosal Abutment Design, Peri-implant Bone Loss
- Trial name
- NCT04385355
- Testing
- Conventional transmucosal abutment design, Narrow transmucosal abutment design
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Santiago de Compostela
Edentulous Alveolar Ridge
Evaluation of Marginal Bone Loss of Two Immediately Loaded Implants Retaining Mandibular Overdenture
It is a randomized control clinical trial in which maxillary and mandibular dentures will be constructed, two implants will be inserted in the inter foraminal region in the edentulous mandible and immediate loading will be done.
- Trial name
- NCT06150755
- Testing
- implant supported overdenture by ball, implant supported overdenture by bar
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periimplantitis, Marginal Bone Loss
A Study of the Crestal Bone Loss Around Bone Level Versus Tissue Level Implants in Non-compliant Patients With Healthy or Reduced Periodontium After 5-8 Years in Function
The goal is to evaluate, after 5 to 8 years, the marginal bone loss around tissue-level implants and bone-level implants in patients who have not followed the maintenance program.
- Trial name
- NCT04942808
- Testing
- Periapical radiographs
- Where
- Lebanon
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Tooth Loss, Surface Treatment
Effect of Different Loading Protocols on Photofunctionalized Implants in the Posterior Maxilla
This randomized clinical trial evaluates different loading protocols for UV-photofunctionalized dental implants in the posterior maxilla. Clinical and radiographic outcomes will be assessed during follow
- Conditions
- Tooth Loss, Surface Treatment, Immediate Dental Implant Loading, Implant Loading
- Trial name
- PHOTOLOAD (NCT07700914)
- Testing
- Immediate loading of UV-photofunctionalized dental implants, Early loading of UV-photofunctionalized dental implants, Conventional loading of UV-photofunctionalized dental implants
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Dental Implant Failed, Peri-Implantitis
20-year Implant Survival in Periodontally Healthy and Compromised Patients
The aim of this study will be to compare the long-term outcomes of sandblasted and acid-etched (SLA) implants in patients previously treated for periodontitis and in periodontally healthy patients (PHP) after a follow-up of at…
- Conditions
- Dental Implant Failed, Peri-Implantitis, Bone Loss
- Trial name
- NCT04983758
- Testing
- Oral Rehabilitation with dental implants
- Where
- Italy
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Alveolar Bone Loss, Dental Implant Failure Nos
Stability of the Marginal Bone Around Subcrestal Implants
The extent of marginal bone remodeling around the neck of dental implants has been used for many years as a criterion for defining their long-term success. Apico-coronal position represents a crucial factor in this field.
- Trial name
- NCT05494476
- Testing
- implant insertion
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Bone Loss
Milled in Versus Round Bar for Mini-implant Retained Mandibular Overdentures
purpose: The primary purpose of this retrospective radiographic study were conducted to compare between milled bar and round bar for mini implant retained overdentures (IODs) on peri-implant bone changes and posterior mandibular…
- Trial name
- NCT06185283
- Testing
- panoramic x-ray
- Volunteers
- 18 people
- Sponsor
- Mansoura University
Tooth Loss / Rehabilitation, Dental Implant
Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial
This study will compare the effect of standard-dose and micro-dose recombinant human bone morphogenetic protein-2 (rhBMP-2) with a placebo control on dental implant stability in the posterior mandible.
- Conditions
- Tooth Loss / Rehabilitation, Dental Implant, Osseo-Integrated Implants
- Trial name
- SMBMP (NCT07696299)
- Testing
- Standard-dose rhBMP-2, Micro-dose rhBMP-2, Sterile Normal Saline
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Baghdad