Clinical trials: Peri-implant Bone Loss, open to volunteers
Tooth Loss, Alveolar Bone Loss
Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket Classes
Immediate implant placement into a fresh extraction socket shortens overall treatment time and reduces the number of surgical procedures, but the fit between the implant and the socket walls, and the resulting soft-tissue…
- Conditions
- Tooth Loss, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- IMPLA-CHA (NCT07801573)
- Testing
- Immediate implant placement with customized healing abutment
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Plovdiv Medical University
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Alveolar Bone Atrophy, Alveolar Bone Grafting
Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.
Maxillary posterior area is the most challenging site for dental implant placement. Indeed, complex remodeling processes, resulting in changes of the maxillary sinus and shape of the alveolar ridge will cause difficulties in…
- Conditions
- Alveolar Bone Atrophy, Alveolar Bone Grafting, Peri-Implant Health, Sinus Floor Augmentation
- Trial name
- NCT07526337
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Tooth Loss / Rehabilitation, Dental Implant
Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled Trial
This study will compare the effect of standard-dose and micro-dose recombinant human bone morphogenetic protein-2 (rhBMP-2) with a placebo control on dental implant stability in the posterior mandible.
- Conditions
- Tooth Loss / Rehabilitation, Dental Implant, Osseo-Integrated Implants
- Trial name
- SMBMP (NCT07696299)
- Testing
- Standard-dose rhBMP-2, Micro-dose rhBMP-2, Sterile Normal Saline
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- University of Baghdad
Marginal Bone Loss, One-piece Implants Versus Two-piece Implants During the Osseointegration Phase
Comparative Evaluation Between One-piece and Two-piece Implants Supporting Mandibular Screw-retained All-On-Four Full-arch Prosthesis on Peri-implant Bone Changes.
Evaluating the bone changing after receiving one-piece implants supported full arch prosthesis compared to the conventional two-piece implants.
- Trial name
- RCT (NCT06790524)
- Testing
- One-piece dental implants with MUA, Two-piece dental implants
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs
Peri-implant Tissues Changes for Different Abutment Shapes and Heights
The goal of this randomized clinical trial is to investigate the influence of supracrestal soft tissue on abutments of different heights (2-mm vs. 3-mm) and shapes (cylindrical abutment vs.
- Conditions
- Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- NCT07509281
- Testing
- Bone-Level Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Peri-implantitis, Peri-implant Bone Loss
Access to Probing and Peri-implant Diseases
This multicenter cross-sectional study aims to evaluate the association between access to peri-implant probing and radiographic peri-implant bone loss.
- Trial name
- NCT07557459
- Testing
- Peri-implant probing
- Where
- 9 sites in Spain
- Volunteers
- 281 people
- Sponsor
- Arrow Development
Bone Loss in Jaw
Mandibular Overdentures vs All-on-4 With PEEK
This study compares long-term peri-implant outcomes between two mandibular full-arch rehabilitation approaches-four-implant-retained overdentures and All-on-4 fixed prostheses-when both are fabricated with polyetheretherketone…
- Trial name
- NCT07137533
- Testing
- Mandibular Four-Implant-Retained Overdenture (PEEK Framework); Mandibular All-on-4 Fixed Prosthesis (PEEK Framework)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque
Impact of Abutment Screw Torque on Marginal Bone Loss
The objective of this clinical trial is to evaluate the impact of different torque values applied during transmucosal abutment placement in dental implants on marginal bone loss and peri-implant parameters, including the…
- Conditions
- Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque, PROMS According to the Abutment Torque, Marginal Bone Loss According to the Abutment Torque
- Trial name
- NCT07234552
- Testing
- Abutment torqued to 15 Ncm, Pilar torqued to 30 Ncm, 2 mm healing cap
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University
Medication Related Osteonecrosis of the Jaw
Comparing Implant Retention Versus Removal for MRONJ at Implant Sites
Medication-related osteonecrosis of the jaw (MRONJ) is a condition that can occur in patients who take medications such as antiresorptive drugs for osteoporosis and other bone-related systemic diseases.
- Trial name
- NCT07435259
- Testing
- Implant Retention Surgery, Implant Removal Sugery
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyunghee University Dental Hospital